Journal of Microbiology

Reviews

Prions in Microbes: The Least in the Most: Moonil Son , Sia Han , Seyeon Lee; J. Microbiol. 2023;61(10):881-889. Published online September 5, 2023; DOI: https://doi.org/10.1007/s12275-023-00070-4

68 View
0 Download
1 Web of Science
1 Crossref

Prions are infectious proteins that mostly replicate in self-propagating amyloid conformations (filamentous protein polymers) and consist of structurally altered normal soluble proteins. Prions can arise spontaneously in the cell without any clear reason and are generally considered fatal disease-causing agents that are only present in mammals. However, after the seminal discovery of two prions, [PSI+] and [URE3], in the eukaryotic model microorganism Saccharomyces cerevisiae, at least ten more prions have been discovered, and their biological and pathological effects on the host, molecular structure, and the relationship between prions and cellular components have been studied. In a filamentous fungus model, Podospora anserina, a vegetative incomparability-related [Het-s] prion that directly triggers cell death during anastomosis (hyphal fusion) was discovered. These prions in eukaryotic microbes have extended our understanding to overcome most fatal human prion/amyloid diseases. A prokaryotic microorganism (Clostridium botulinum) was reported to have a prion analog. The transcriptional regulators of C. botulinum-Rho can be converted into the self-replicating prion form ([RHO-X-C+]), which may affect global transcription. Here, we outline the major issues with prions in microbes and the lessons learned from the relatively uncovered microbial prion world.

Citations

Citations to this article as recorded by

A Story Between s and S: [Het-s] Prion of the Fungus Podospora anserina
Moonil Son
Mycobiology.2024; 52(2): 85. CrossRef

The osmotic stress response operon betIBA is under the functional regulation of BetI and the quorum-sensing regulator AnoR in Acinetobacter nosocomialis: Bindu Subhadra , Surya Surendran , Bo Ra Lim , Jong Sung Yim , Dong Ho Kim , Kyungho Woo , Hwa-Jung Kim , Man Hwan Oh , Chul Hee Choi; J. Microbiol. 2020;58(6):519-529. Published online May 27, 2020; DOI: https://doi.org/10.1007/s12275-020-0186-1

51 View
0 Download
11 Web of Science
9 Crossref

Abstract

Adaptation to changing environmental conditions is crucial for the survival of microorganisms. Bacteria have evolved various mechanisms to cope with osmotic stress. Here, we report the identification and functional characterization of the osmotic stress response operon, betIBA, in Acinetobacter nosocomialis. The betIBA operon encodes enzymes that are important for the conversion of choline to the osmoprotectant, glycine betaine. The betIBA operon is polycistronic and is under the regulation of the first gene, betI, of the same operon. A bioinformatics analysis revealed the presence of a BetI-binding motif upstream of the betIBA operon, and electrophoretic mobility shift assays confirmed the specific binding of BetI. An mRNA expression analysis revealed that expression of betI, betB, and betA genes is elevated in a betIeletion mutant compared with the wild type, confirming that the autorepressor BetI represses the betIBA operon in A. nosocomialis. We further found that the betIBA operon is under the transcriptional control of the quorum-sensing (QS) regulator, AnoR in, A. nosocomialis. A subsequent analysis of the impact of BetI on expression of the QS genes, anoR and anoI, demonstrated that BetI acts as a repressor of anoR and anoI. In addition, it was noticed that the osmotic stress response regulator, OmpR might play an important role in controlling the expression of betIBA operon in A. nosocomialis. Collectively, these data demonstrate that QS and osmotic stress-response systems are correlated in A. nosocomialis and that the expression of genes in both systems is finely tuned by various feedback loops depending on osmolarity conditions.

Citations

Citations to this article as recorded by

Metabolome analysis revealed the critical role of betaine for arsenobetaine biosynthesis in the marine medaka (Oryzias melastigma)
Qianyu Zhao, Qiao-Guo Tan, Wen-Xiong Wang, Peng Zhang, Zijun Ye, Liping Huang, Wei Zhang
Environmental Pollution.2024; 359: 124612. CrossRef
The atypical organization of the luxI/R family genes in AHL-driven quorum-sensing circuits
Yuyuan Cai, Xuehong Zhang, Michael J. Federle
Journal of Bacteriology.2024;[Epub] CrossRef
The Transcriptomic Response of Cells of the Thermophilic Bacterium Geobacillus icigianus to Terahertz Irradiation
Sergey Peltek, Svetlana Bannikova, Tamara M. Khlebodarova, Yulia Uvarova, Aleksey M. Mukhin, Gennady Vasiliev, Mikhail Scheglov, Aleksandra Shipova, Asya Vasilieva, Dmitry Oshchepkov, Alla Bryanskaya, Vasily Popik
International Journal of Molecular Sciences.2024; 25(22): 12059. CrossRef
Mycobacterium smegmatis MraZ Regulates Multiple Genes within and Outside of the dcw Operon during Hypoxia
Ismail Mohamed Suleiman, Huang Yu, Junqi Xu, Junfeng Zhen, Hongxiang Xu, Abulimiti Abudukadier, Amina Rafique Hafiza, Jianping Xie
ACS Infectious Diseases.2024; 10(12): 4301. CrossRef
Online Omics Platform Expedites Industrial Application of Halomonas bluephagenesis TD1.0
Helen Park, Matthew Faulkner, Helen S Toogood, Guo-Qiang Chen, Nigel Scrutton
Bioinformatics and Biology Insights.2023;[Epub] CrossRef
The Effect of Proline on the Freeze-Drying Survival Rate of Bifidobacterium longum CCFM 1029 and Its Inherent Mechanism
Shumao Cui, Wenrui Zhou, Xin Tang, Qiuxiang Zhang, Bo Yang, Jianxin Zhao, Bingyong Mao, Hao Zhang
International Journal of Molecular Sciences.2022; 23(21): 13500. CrossRef
Regulator of RNase E activity modulates the pathogenicity of Salmonella Typhimurium
Jaejin Lee, Eunkyoung Shin, Ji-Hyun Yeom, Jaeyoung Park, Sunwoo Kim, Minho Lee, Kangseok Lee
Microbial Pathogenesis.2022; 165: 105460. CrossRef
The Flagellar Transcriptional Regulator FtcR Controls Brucella melitensis 16M Biofilm Formation via a betI-Mediated Pathway in Response to Hyperosmotic Stress
Jia Guo, Xingmei Deng, Yu Zhang, Shengnan Song, Tianyi Zhao, Dexin Zhu, Shuzhu Cao, Peter Ivanovic Baryshnikov, Gang Cao, Hugh T. Blair, Chuangfu Chen, Xinli Gu, Liangbo Liu, Hui Zhang
International Journal of Molecular Sciences.2022; 23(17): 9905. CrossRef
Stressed out: Bacterial response to high salinity using compatible solute biosynthesis and uptake systems, lessons from Vibrionaceae
Gwendolyn J. Gregory, E. Fidelma Boyd
Computational and Structural Biotechnology Journal.2021; 19: 1014. CrossRef

Journal Article

Gallibacterium elongation factor-Tu possesses amyloid-like protein characteristics, participates in cell adhesion, and is present in biofilms: Jaqueline López-Ochoa , J. Fernando Montes-García , Candelario Vázquez , Patricia Sánchez-Alonso , Victor M. Pérez-Márquez , Patrick J. Blackall , Sergio Vaca , Erasmo Negrete-Abascal; J. Microbiol. 2017;55(9):745-752. Published online September 2, 2017; DOI: https://doi.org/10.1007/s12275-017-7077-0

54 View
0 Download
26 Crossref

Abstract

Gallibacterium, which is a bacterial pathogen in chickens, can form biofilms. Amyloid proteins present in biofilms bind Congo red dye. The aim of this study was to characterize the cell-surface amyloid-like protein expressed in biofilms formed by Gallibacterium strains and determine the relationship between this protein and curli, which is an amyloid protein that is commonly expressed by members of the Enterobacteriaceae family. The presence of amyloid-like proteins in outer membrane protein samples from three strains of G. anatis and one strain of Gallibacterium genomospecies 2 was evaluated. A protein identified as elongation factor-Tu (EF-Tu) by mass spectrometric analysis and in silico analysis was obtained from the G. anatis strain F149T. This protein bound Congo red dye, cross-reacted with anti-curli polyclonal serum, exhibited polymerizing properties and was present in biofilms. This protein also reacted with pooled serum from chickens that were experimentally infected with G. anatis, indicating the in vivo immunogenicity of this protein. The recombinant EF-Tu purified protein, which was prepared from G. anatis 12656-12, polymerizes under in vitro conditions, forms filaments and interacts with fibronectin and fibrinogen, all of which suggest that this protein functions as an adhesin. In summary, EF-Tu from G. anatis presents amyloid characteristics, is present in biofilms and could be relevant for the pathogenesis of G. anatis.

Citations

Citations to this article as recorded by

Isolation and characterization of a Mannheimia haemolytica secreted serine protease that degrades sheep and bovine fibrinogen
Verónica Rosales-Islas, Gerardo Antonio Ramírez-Paz-y-Puente, Fernando Montes-García, Candelario Vázquez-Cruz, Patricia Sánchez-Alonso, Edgar Zenteno, Erasmo Negrete-Abascal
Microbial Pathogenesis.2024; 192: 106706. CrossRef
Epinephrine and norepinephrine regulate the expression of virulence factors in Gallibacterium anatis
Pablo A. Rea Hernández, Gerardo A. Ramírez-Paz-y-Puente, Fernando Montes-García, Candelario Vázquez-Cruz, Patricia Sanchez-Alonso, Maria Elena Cobos-Justo, Edgar Zenteno, Erasmo Negrete-Abascal
Microbial Pathogenesis.2024; 196: 106987. CrossRef
The Description and Analysis of the Complete Genome of Dermacoccus barathri FBCC-B549 Strain
Yeha Kim, Hyaekang Kim, Jina Kim, Ji-Hye Han, Eu Jin Chung, Seung Won Nam, Miyoung Shin, Woori Kwak
Microorganisms.2024; 12(6): 1227. CrossRef
Utilization of non-pathogenic bacteria to obtain optimum biofilm production for beneficial applications
Sonali Rana, Lata Sheo Bachan Upadhyay
Brazilian Journal of Microbiology.2023; 54(3): 1875. CrossRef
Gallibacterium anatis infection in poultry: a comprehensive review
Wafaa A. Abd El-Ghany, Abdelazeem M. Algammal, Helal F. Hetta, Ahmed R. Elbestawy
Tropical Animal Health and Production.2023;[Epub] CrossRef
Cyclic di‐GMP signaling—Where did you come from and where will you go?
Ute Römling
Molecular Microbiology.2023; 120(4): 564. CrossRef
Testosterone and estradiol modify the expression of adhesins and biofilm formation in Actinobacillus seminis
Gerardo Antonio Ramírez-Paz-y-Puente, Carlos I Chávez-Flores, J Fernando Montes-García, Patricia G Sanchez-Alonso, Maria Elena Cobos-Justo, Candelario Vázquez-Cruz, Edgar Zenteno, Erasmo Negrete-Abascal
FEMS Microbiology Letters.2023;[Epub] CrossRef
A Maverick-like cluster in the genome of a pathogenic, moderately virulent strain of Gallibacterium anatis, ESV200, a transient biofilm producer
Patricia Sanchez-Alonso, Elena Cobos-Justo, Miguel Angel Avalos-Rangel, Lucía López-Reyes, Gloria Luz Paniagua-Contreras, Felipe Vaca-Paniagua, Estela Anastacio-Marcelino, Ana Jaqueline López-Ochoa, Victor M. Pérez Marquez, Erasmo Negrete-Abascal, Candela
Frontiers in Microbiology.2023;[Epub] CrossRef
Mannheimia haemolytica OmpH binds fibrinogen and fibronectin and participates in biofilm formation
Cecilia Figueroa-Valenzuela, J. Fernando Montes-García, Candelario Vazquez-Cruz, Edgar Zenteno, Mohamed Alí Pereyra, Erasmo Negrete-Abascal
Microbial Pathogenesis.2022; 172: 105788. CrossRef
Probiotic Gastrointestinal Transit and Colonization After Oral Administration: A Long Journey
Shengyi Han, Yanmeng Lu, Jiaojiao Xie, Yiqiu Fei, Guiwen Zheng, Ziyuan Wang, Jie Liu, Longxian Lv, Zongxin Ling, Björn Berglund, Mingfei Yao, Lanjuan Li
Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef
Two Decades of Studying Functional Amyloids in Microorganisms
Shon A. Levkovich, Ehud Gazit, Dana Laor Bar-Yosef
Trends in Microbiology.2021; 29(3): 251. CrossRef
Quantitative proteomic analysis of marine biofilms formed by filamentous cyanobacterium
M.J. Romeu, D. Domínguez-Pérez, D. Almeida, J. Morais, M.J. Araújo, H. Osório, A. Campos, V. Vasconcelos, F.J. Mergulhão
Environmental Research.2021; 201: 111566. CrossRef
Identification of amyloidogenic proteins in the microbiomes of a rat Parkinson's disease model and wild‐type rats
Line Friis Bakmann Christensen, Saeid Hadi Alijanvand, Michał Burdukiewicz, Florian‐Alexander Herbst, Henrik Kjeldal, Morten Simonsen Dueholm, Daniel E. Otzen
Protein Science.2021; 30(9): 1854. CrossRef
Searching for Biological Function of the Mysterious PA2504 Protein from Pseudomonas aeruginosa
Joanna Drabinska, Kamil Steczkiewicz, Martyna Kujawa, Elżbieta Kraszewska
International Journal of Molecular Sciences.2021; 22(18): 9833. CrossRef
Amyloidogenic Peptides in Human Neuro-Degenerative Diseases and in Microorganisms: A Sorrow Shared Is a Sorrow Halved?
Kristina Endres
Molecules.2020; 25(4): 925. CrossRef
Etiology, epidemiology, pathology, and advances in diagnosis, vaccine development, and treatment ofGallibacterium anatisinfection in poultry: a review
Dharanesha Narasinakuppe Krishnegowda, Kuldeep Dhama, Asok Kumar Mariappan, Palanivelu Munuswamy, Mohd. Iqbal Yatoo, Ruchi Tiwari, Kumaragurubaran Karthik, Prakash Bhatt, Maddula Ramakoti Reddy
Veterinary Quarterly.2020; 40(1): 16. CrossRef
Respiratory and Reproductive Impairment of Commercial Layer Chickens After Experimental Infection with Gallibacterium anatis Biovar haemolytica
Ahmed R. Elbestawy, Hoda A. Abd-Ellatieff, Hany F. Ellakany, Hatem S. Abd El-Hamid, Abdelrahman A. Abou Rawash, Ahmed R. Gado, Ayman H. Abd El-Aziz, Amal A. M. Eid, Nahed A. El-Shall
Avian Diseases.2020;[Epub] CrossRef
Characterization of Actinobacillus seminis biofilm formation
J. Fernando Montes García, Lourdes Rojas, Edgar Zenteno, Candelario Vazquez Cruz, Erasmo Negrete Abascal
Antonie van Leeuwenhoek.2020; 113(9): 1371. CrossRef
Biological Functions of Prokaryotic Amyloids in Interspecies Interactions: Facts and Assumptions
Anastasiia O. Kosolapova, Kirill S. Antonets, Mikhail V. Belousov, Anton A. Nizhnikov
International Journal of Molecular Sciences.2020; 21(19): 7240. CrossRef
Properties of a modified quaternary ammonium silane formulation as a potential root canal irrigant in endodontics
Umer Daood, Abhishek Parolia, Jukka Matinlinna, Cynthia Yiu, Hany Mohamed Aly Ahmed, Amr Fawzy
Dental Materials.2020; 36(12): e386. CrossRef
Actinobacillus seminis GroEL-homologous protein agglutinates sheep erythrocytes
Juan Fernando Montes-García, Willy Angel Delgado-Tapia, Candelario Vazquez-Cruz, Sergio Vaca, Ariadnna Cruz-Córdova, Erasmo Negrete-Abascal
Antonie van Leeuwenhoek.2019; 112(11): 1655. CrossRef
The Diverse Functional Roles of Elongation Factor Tu (EF-Tu) in Microbial Pathogenesis
Kate L. Harvey, Veronica M. Jarocki, Ian G. Charles, Steven P. Djordjevic
Frontiers in Microbiology.2019;[Epub] CrossRef
Raman Spectroscopic Characterization of Endodontic Biofilm Matrices
Tatiana Ramirez-Mora, Claudia Dávila-Pérez, Fernando Torres-Méndez, Grettel Valle-Bourrouet
Journal of Spectroscopy.2019; 2019: 1. CrossRef
Functional Amyloid and Other Protein Fibers in the Biofilm Matrix
Elliot Erskine, Cait E. MacPhee, Nicola R. Stanley-Wall
Journal of Molecular Biology.2018; 430(20): 3642. CrossRef
Identification of two adhesins of Actinobacillus seminis
J. Fernando Montes-García, Delil A. Chincoya Martinez, Sergio Vaca Pacheco, Candelario Vázquez Cruz, Patricia Sanchez Alonso, Juan Xicohtencatl Cortes, Hector Trujillo-Ruiz, Erasmo Negrete-Abascal
Small Ruminant Research.2018; 167: 100. CrossRef
Mannheimia haemolytica OmpP2-like is an amyloid-like protein, forms filaments, takes part in cell adhesion and is part of biofilms
J. F. Montes García, Sergio Vaca, Norma L. Delgado, Alina Uribe-García, Candelario Vázquez, P. Sánchez Alonso, J. Xicohtencatl Cortes, A. Cruz Cordoba, E. Negrete Abascal
Antonie van Leeuwenhoek.2018; 111(12): 2311. CrossRef

Research Support, Non-U.S. Gov't

Effect of Mycelial Extract of Clavicorona pyxidata on the Production of Amyloid β-Peptide and the Inhibition of Endogenous β-Secretase Activity in vitro: Tae-Hee Lee , Young-Il Park , Yeong-Hwan Han; J. Microbiol. 2006;44(6):665-670.; DOI: https://doi.org/2459 [pii]

36 View
0 Download

Abstract: Amyloid β-peptide (Aβ), which is a product of the proteolytic effect of β-secretase (BACE) on an amyloid precursor protein, is closely associated with Alzheimer’s disease (AD) pathogenesis. There is sufficient evidence to suggest that a BACE inhibitor may reduce Aβ levels, thus decreasing the risk of AD. In a previous study, an extract of Clavicorona pyxidata DGUM 29005 mycelia was found to inhibit the production of a soluble β-amyloid precursor protein (sβAPP), Aβ, and BACE in neuronal cell lines. We sought to determine whether this mycelial extract exerts the same effect in human rhabdomyosarcoma A-204 and rat pheochromocytoma PC-12 cells. We found that the production of Aβ decreased in a dose-dependent manner in the presence of the mycelial extract and that the concentration of Aβ never exceeded 50 μg/ml. The presence of sAPP was detected in every culture medium to which the mycelial extract had been added and its concentration remained the same, regardless of the concentration of the extract used. Endogenous β-secretase <br>activity in A-204 and PC-12 cellular homogenates also decreased in the presence of this extract. These cells, in culture, were not susceptible to the cytotoxic activity of the mycelial extract.

Phylogenetic Relationships of the Aphyllophorales Inferred from Sequence Analysis of Nuclear Small Subunit Ribosomal DNA: Seon Young Kim , Hack Sung Jung; J. Microbiol. 2000;38(3):122-131.

41 View
0 Download

Abstract: Phylogenetic classification of the Aphyllophorales was conducted based on the analysis of nuclear small subunit ribosomal RNA gene (nuc SSU rDNA) sequences. Based on phylogenetic groupings and taxonomic characters, 16 families were recognized and discussed. Although many of the characters had more or less homoplasies, microscopic characters such as the mitic system and clamp, spore amyloidity and rot type appeared to be important in the classification of the Aphyllophorales. Phylogenetically significant families were newly defined to improve the classification of the order Aphyllophorales.

First
Prev
Page of 1
Next
Last

Search