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The crosstalk between bacteria and host autophagy: host defense or bacteria offense
Lin Zheng , Fang Wei , Guolin Li
J. Microbiol. 2022;60(5):451-460.   Published online April 29, 2022
DOI: https://doi.org/10.1007/s12275-022-2009-z
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AbstractAbstract
Xenophagy is a specific selective autophagy for the elimination of intracellular bacteria. Current evidence suggests that the processes for host autophagy system to recognize and eliminate invading bacteria are complex, and vary according to different pathogens. Although both ubiquitin-dependent and ubiquitin-independent autophagy exist in host to defense invading bacteria, successful pathogens have evolved diverse strategies to escape from or paralyze host autophagy system. In this review, we discuss the mechanisms of host autophagy system to recognize and eliminate intracellular pathogens and the mechanisms of different pathogens to escape from or paralyze host autophagy system, with a particular focus on the most extensively studied bacteria.

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  • Xenophagy as a Strategy for Mycobacterium leprae Elimination during Type 1 or Type 2 Leprosy Reactions: A Systematic Review
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    Pathogens.2023; 12(12): 1455.     CrossRef
  • Brucella BtpB Manipulates Apoptosis and Autophagic Flux in RAW264.7 Cells
    Junmei Li, Lin Qi, Ziyang Diao, Mengyu Zhang, Bin Li, Yunyi Zhai, Mingyue Hao, Dong Zhou, Wei Liu, Yaping Jin, Aihua Wang
    International Journal of Molecular Sciences.2022; 23(22): 14439.     CrossRef

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