A cadimium-resistant strain isolated from Anyang stream, Azomonas agilis PY101 exhibited strong resistance to 1000 ppm of cadmium ion (Cd^2+). A agilis PY101 also exhibited resistance to various antibiotics, such as amoxicillin, amplicilin, bacitracin, cefazolin, erythromycin, penicilin, tetracycline, and vancomycin. In the presence of Cd^2+, the growth of A. aglis PY101 started after an extended lag phase and produced a green-fluorescent pigment induced by cadmium. The dramatic decrease (approximately 400ppm) of concentration of cd^2+ in the culture medium during the growth phase of A. agilis PY101 was confirmed by the inductively coupled plasma-atomic emission spectrophotometer. Transmission electron microscopic analysis revealed that A. agilis PY 101 actively accumulated Cd^2+ in the cytoplasm.