MSK
Search
- Page Path
- HOME > Search
Review
- The “Cins” of Our Fathers: Rejuvenated Interest in Colicins to Combat Drug Resistance
- Sumudu Upatissa , Robert J. Mitchell
- J. Microbiol. 2023;61(2):145-158. Published online February 8, 2023
- DOI: https://doi.org/10.1007/s12275-023-00023-x
- 73 View
- 0 Download
- 4 Web of Science
- 4 Crossref
-
Abstract
- With the growing threat of antibiotic resistance, researchers around the globe are seeking alternatives to stem bacterial pathogenesis. One such alternative is bacteriocins, proteins produced by bacterial species to inhibit the growth and viability of related bacterial species. With their diverse mechanisms, which include pore formation and nuclease activities, and narrow spectrum of activities, which limit their impact to only certain bacterial species, unlike many chemical antibiotics, bacteriocins offer intriguing possibilities to selectively control individual bacterial populations. Within this review, therefore, we highlight current research exploring the application of colicins and microcins, a subset of bacteriocins, with an emphasis on their activities against drug-resistant pathogens, both in in vitro and in vivo settings.
-
Citations
Citations to this article as recorded by
- Isolation, Genomics-Based and Biochemical Characterization of Bacteriocinogenic Bacteria and Their Bacteriocins, Sourced from the Gastrointestinal Tract of Meat-Producing Pigs
Ester Sevillano, Irene Lafuente, Nuria Peña, Luis M. Cintas, Estefanía Muñoz-Atienza, Pablo E. Hernández, Juan Borrero
International Journal of Molecular Sciences.2024; 25(22): 12210. CrossRef - Intelligent Biological Networks: Improving Anti-Microbial Resistance Resilience through Nutritional Interventions to Understand Protozoal Gut Infections
Avinash V. Karpe, David J. Beale, Cuong D. Tran
Microorganisms.2023; 11(7): 1800. CrossRef - Pairing Colicins B and E5 with Bdellovibrio bacteriovorus To Eradicate Carbapenem- and Colistin-Resistant Strains of Escherichia coli
Sumudu Upatissa, Wonsik Mun, Robert J. Mitchell, Minsu Kim
Microbiology Spectrum.2023;[Epub] CrossRef - Bacteriocin-Producing Escherichia coli Q5 and C41 with Potential Probiotic Properties: In Silico, In Vitro, and In Vivo Studies
Veronika S. Mihailovskaya, Dmitry A. Sutormin, Marina O. Karipova, Anna B. Trofimova, Victor A. Mamontov, Konstantin Severinov, Marina V. Kuznetsova
International Journal of Molecular Sciences.2023; 24(16): 12636. CrossRef
- Isolation, Genomics-Based and Biochemical Characterization of Bacteriocinogenic Bacteria and Their Bacteriocins, Sourced from the Gastrointestinal Tract of Meat-Producing Pigs
First
Prev
TOP
