Research Support, Non-U.S. Gov't
- Note] Inhibition of quorum sensing in Pseudomonas aeruginosa by two herbal essential oils from Apiaceae family
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Ehsan Sepahi , Saeed Tarighi , Farajollah Shahriari Ahmadi , Abdolreza Bagheri
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J. Microbiol. 2015;53(2):176-180. Published online January 5, 2015
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DOI: https://doi.org/10.1007/s12275-015-4203-8
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Abstract
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Ferula (Ferula asafoetida L.) and Dorema (Dorema aucheri
Bioss.) both from Apiaceae family were tested for their antiquorum
sensing (QS) activity against Pseudomonas aeruginosa.
Both essential oils exhibited anti-QS activity at 25 μg/ml
of concenteration. At this concenteration Ferula fully abolished
and Dorema reduced the violacein production by C.
violaceum. Pyocyanin, pyoverdine, elastase and biofilm production
were decreased in Ferula oil treatments. Dorema
oil reduced pyoverdine and elastase production, while pyocyanin
and biofilm production were not affacted. Expresion
analysis of QS-dependent genes confirmed our phenotypic
data. Our data introduced native Dorema and Ferula plants
as novel QS and virulence inhibitors.
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Citations
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