Journal of Microbiology

Research Article

LasB activation in Pseudomonas aeruginosa: Quorum sensing-mediated release of an auto-activation inhibitor: Cheol Seung Lee, Xi-Hui Li, Chae-Ran Jeon, Joon-Hee Lee; J. Microbiol. 2025;63(2):e2411005. Published online February 27, 2025; DOI: https://doi.org/10.71150/jm.2411005

499 View
21 Download

Abstract PDF: Pseudomonas aeruginosa secretes three major proteases: elastase B (LasB), protease IV (PIV), and elastase A (LasA), which play crucial roles in infection and pathogenesis. These proteases are activated sequentially from LasB in a proteolytic cascade, and LasB was previously thought to undergo auto-activation. However, our previous study suggested that LasB cannot auto-activate independently but requires additional quorum sensing (QS)-dependent factors for activation, as LasB remained inactive in QS-deficient P. aeruginosa (QS^-) even under artificial overexpression. In this study, we provide evidence for the existence of a LasB inhibitor in QS^- mutants: inactive LasB overexpressed in QS^- strains was in its processed form and could be reactivated upon purification; when full-length LasB was overexpressed in Escherichia coli, a heterologous bacterium lacking both LasB activators and inhibitors, the protein underwent normal processing and activation; and purified active LasB was significantly inhibited by culture supernatant (CS) from QS^- strains but not by CS from QS⁺ strains. These findings demonstrate that a LasB inhibitor exists in QS^- strains, and in its absence, LasB can undergo auto-activation without requiring an activator. Based on these results, we propose an updated hypothesis: the QS-dependent LasB activator functions by removing the LasB inhibitor rather than acting directly on LasB itself, thus preventing premature LasB activation until QS response is initiated.

Journal Articles

Mutational analysis on stable expression and LasB inhibition of LasB propeptide in Pseudomonas aeruginosa: Youngsun Shin , Xi-Hui Li , Cheol Seung Lee , Joon-Hee Lee; J. Microbiol. 2022;60(7):727-734. Published online May 25, 2022; DOI: https://doi.org/10.1007/s12275-022-1671-5

45 View
0 Download

Abstract: Three major proteases, elastase B (LasB), protease IV (PIV), and elastase A (LasA) expressed in Pseudomonas aeruginosa play important roles in infections and pathogeneses. These are activated by a proteolytic cascade initiated by the activation of LasB. In this study, we investigated whether LasB could be inhibited using its propeptide (LasBpp). Although LasA and PIV were inhibited by their propeptides, LasB was not inhibited by purified LasBpp because LasB degraded LasBpp. To address this problem, mutant LasBpp variants were constructed to obtain a mutant LasBpp resistant to LasB degradation. A C-terminal deletion series of LasBpp was tested in vivo, and two positive candidates, T2 and T2-1, were selected. However, both caused growth retardation and were unstably expressed in vivo. Since deleting the C-terminal end of LasBpp significantly affected its stable expression, substitution mutations were introduced at the two amino acids near the truncation site of T2-1. The resulting mutants, LasBppE172D, LasBppG173A, and LasBppE172DG173A, significantly diminished LasB activity when overexpressed in vivo and were stably expressed in MW1, a quorum sensing mutant that does not produce LasB. In vitro analysis showed that purified LasBppE172DG173A inhibited LasB activity to a small extent. Summarizing, Cterminal modification of LasBpp profoundly affected the stable expression of LasBpp, and little enhanced the ability of LasBpp to resist degradation by LasB.

Characterization of components of a reducing system for SoxR in the cytoplasmic membrane of Escherichia coli: Kang-Lok Lee , Kyung-Chang Lee , Joon-Hee Lee , Jung-Hye Roe; J. Microbiol. 2022;60(4):387-394. Published online March 28, 2022; DOI: https://doi.org/10.1007/s12275-022-1667-1

64 View
0 Download
3 Web of Science
3 Crossref

Abstract

A reducing system of SoxR, a regulator of redox-active molecules, was identified as rsxABCDGE gene products and RseC in Escherichia coli through genetic studies. We found that ApbE was an additional component of the reducer system. Bacterial two hybrid analysis revealed that these proteins indeed had multiple interactions among themselves. RseC and RsxB formed the core of the complex, interacting with more than five other components. RsxC, the only cytoplasmic component of the system, interacted with SoxR. It might be linked with the rest of the complex via RsxB. Membrane fractions containing the wild type complex but not the mutant complex reduced purified SoxR using NADH as an electron source. These results suggest that Rsx genes, RseC, and ApbE can form a complex using NAD(P)H to reduce SoxR.

Citations

Citations to this article as recorded by

AcrAB-TolC efflux pump overexpression and tet(A) gene mutation increase tigecycline resistance in Klebsiella pneumoniae
Zhaoxin Xia, Jing zhou, Nana Gao, Ge Li, Runde Liu, Guoping Lu, Jilu Shen
World Journal of Microbiology and Biotechnology.2024;[Epub] CrossRef
The Na+-translocating NADH:quinone oxidoreductase (Na+-NQR): Physiological role, structure and function of a redox-driven, molecular machine
Julia Steuber, Günter Fritz
Biochimica et Biophysica Acta (BBA) - Bioenergetics.2024; 1865(4): 149485. CrossRef
Functional analysis of bacterial genes accidentally packaged in rhizospheric phageome of the wild plant species Abutilon fruticosum
Ruba Abdulrahman Ashy
Saudi Journal of Biological Sciences.2023; 30(10): 103789. CrossRef

Antibiofilm effect of biofilm-dispersing agents on clinical isolates of Pseudomonas aeruginosa with various biofilm structures: Soo-Kyoung Kim , Xi-Hui Li , Hyeon-Ji Hwang , Joon-Hee Lee; J. Microbiol. 2018;56(12):902-909. Published online October 25, 2018; DOI: https://doi.org/10.1007/s12275-018-8336-4

57 View
0 Download
6 Crossref

Abstract

Pseudomonas aeruginosa, an opportunistic human pathogen, causes many biofilm-mediated chronic infections. In this study, biofilm structures of various clinical strains of P. aeruginosa isolated from hospitalized patients were examined and their influence on the biofilm-dispersing effects of chemicals was investigated. The clinical isolates formed structurally distinct biofilms that could be classified into three different groups: 1) mushroom-like, 2) thin flat, and 3) thick flat structures. A dispersion of these differently structured biofilms was induced using two biofilm-dispersing agents, anthranilate and sodium nitroprusside (SNP). Although both SNP and anthranilate could disperse all types of biofilms, the thick flat biofilms were dispersed less efficiently than the biofilms of other structures. This suggests that biofilm-dispersing agents have higher potency on the biofilms of porous structures than on densely packed biofilms.

Citations

Citations to this article as recorded by

New insights into antimicrobial and antibiofilm effects of edible mushrooms
Ashaimaa Y. Moussa, Shaimaa Fayez, Hang Xiao, Baojun Xu
Food Research International.2022; 162: 111982. CrossRef
Modified poly(L-lysine)-based structures as novel antimicrobials for diabetic foot infections, an in-vitro study
Alicia Grace, Robert Murphy, Aoife Dillon, Diarmuid Smith, Sally-Ann Cryan, Andreas Heise, Deirdre Fitzgerald-Hughes
HRB Open Research.2022; 5: 4. CrossRef
Anthranilate Acts as a Signal to Modulate Biofilm Formation, Virulence, and Antibiotic Tolerance of Pseudomonas aeruginosa and Surrounding Bacteria
Hyeon-Ji Hwang, Xi-Hui Li, Soo-Kyoung Kim, Joon-Hee Lee, Cezar M. Khursigara
Microbiology Spectrum.2022;[Epub] CrossRef
Early plaque formation on PTFE membranes with expanded or dense surface structures applied in the oral cavity of human volunteers
Alberto Turri, Emina Čirgić, Furqan A. Shah, Maria Hoffman, Omar Omar, Christer Dahlin, Margarita Trobos
Clinical and Experimental Dental Research.2021; 7(2): 137. CrossRef
Antipathogenic Compounds That Are Effective at Very Low Concentrations and Have Both Antibiofilm and Antivirulence Effects against Pseudomonas aeruginosa
Hyeon-Ji Hwang, Heejeong Choi, Sojeong Hong, Hyung Ryong Moon, Joon-Hee Lee, Amanda G. Oglesby
Microbiology Spectrum.2021;[Epub] CrossRef
Thermoregulation of Pseudomonas aeruginosa Biofilm Formation
Suran Kim, Xi-Hui Li, Hyeon-Ji Hwang, Joon-Hee Lee, Danilo Ercolini
Applied and Environmental Microbiology.2020;[Epub] CrossRef

Reviews

[Minireview] Antibiofilm agents: A new perspective for antimicrobial strategy: Xi-Hui Li , Joon-Hee Lee; J. Microbiol. 2017;55(10):753-766. Published online September 28, 2017; DOI: https://doi.org/10.1007/s12275-017-7274-x

55 View
0 Download
118 Crossref

Abstract

Biofilms are complex microbial architectures that attach to surfaces and encase microorganisms in a matrix composed of self-produced hydrated extracellular polymeric substances (EPSs). In biofilms, microorganisms become much more resistant to antimicrobial treatments, harsh environmental conditions, and host immunity. Biofilm formation by microbial pathogens greatly enhances survival in hosts and causes chronic infections that result in persistent inflammation and tissue damages. Currently, it is believed over 80% of chronic infectious diseases are mediated by biofilms, and it is known that conventional antibiotic medications are inadequate at eradicating these biofilm-mediated infections. This situation demands new strategies for biofilm-associated infections, and currently, researchers focus on the development of antibiofilm agents that are specific to biofilms, but are nontoxic, because it is believed that this prevents the development of drug resistance. Here, we review the most promising antibiofilm agents undergoing intensive research and development.

Citations

Citations to this article as recorded by

Quinic acid enhances kanamycin efficacy against methicillin-resistant Staphylococcus aureus biofilms
Borel Ndezo Bisso, Humera Jahan, Jean Paul Dzoyem, M. Iqbal Choudhary
Microbial Pathogenesis.2025; 198: 107145. CrossRef
Customized Lanthanide Nanobiohybrids for Noninvasive Precise Phototheranostics of Pulmonary Biofilm Infection
Zhuo Li, Shan Lu, Wenzhen Liu, Zhuo Chen, Yunmei Huang, Xingjun Li, Jiacheng Gong, Xueyuan Chen
ACS Nano.2024; 18(18): 11837. CrossRef
Investigation of Pseudomonas aeruginosa bacteria in a number of Baghdad schools and extent of their resistance to disinfectants and sterilizers
Shaimaa Hadi Al-Dulaimi, Miyada Kh Hassan
Arab Gulf Journal of Scientific Research.2024; 42(4): 1805. CrossRef
Role of small molecules and nanoparticles in effective inhibition of microbial biofilms: A ray of hope in combating microbial resistance
Rohith Gattu, Sanjay S. Ramesh, Suhas Ramesh
Microbial Pathogenesis.2024; 188: 106543. CrossRef
Synthesis, Structural Characterization, and Biological Activities of 1,3,4‐ Thiadiazole Derivatives Containing Sulfonylpiperazine Structures
You‐hua Liu, Fa‐li Wang, Xiao‐li Ren, Chang‐kun Li, Lin‐hong Jin, Xia Zhou
Chemistry & Biodiversity.2024;[Epub] CrossRef
Electrochemical biosensors on microfluidic chips as promising tools to study microbial biofilms: a review
Adei Abouhagger, Raimonda Celiešiūtė-Germanienė, Neringa Bakute, Arunas Stirke, Wanessa C. M. A. Melo
Frontiers in Cellular and Infection Microbiology.2024;[Epub] CrossRef
Revolution of artificial intelligence in antimicrobial, anti-biofilm, and anti-inflammatory techniques: Smart photo-sonodynamic appliance in the internet of dental things (IoDT)
Maryam Pourhajibagher, Rashin Bahrami, Abbas Bahador
Medical Hypotheses.2024; 184: 111270. CrossRef
Phage-Derived Endolysins Against Resistant Staphylococcus spp.: A Review of Features, Antibacterial Activities, and Recent Applications
Mina Golban, Javad Charostad, Hossein Kazemian, Hamid Heidari
Infectious Diseases and Therapy.2024;[Epub] CrossRef
Medical Scope of Biofilm and Quorum Sensing during Biofilm Formation: Systematic Review
Mulat Erkihun, Zelalem Asmare, Kirubel Endalamew, Birhanu Getie, Teklehaimanot Kiros, Ayenew Berhan
Bacteria.2024; 3(3): 118. CrossRef
A Gas Therapy Strategy for Intestinal Flora Regulation and Colitis Treatment by Nanogel‐Based Multistage NO Delivery Microcapsules
Ya‐Jun Fu, Xing Zhao, Li‐Ya Wang, Kai Li, Niu Jiang, Shu‐Ting Zhang, Rao‐Kaijuan Wang, Yi‐Fan Zhao, Wei Yang
Advanced Materials.2024;[Epub] CrossRef
Controlling Staphylococcus aureus biofilm on food contact surfaces: the efficacy of Oliveria decumbens essential oil and its implications on biofilm-related genes
Mahshad Javid Moghadam, Siavash Maktabi, Mehdi Zarei, Pezhman Mahmoodi
Journal of Applied Microbiology.2024;[Epub] CrossRef
Isolation of 2,2′-azoxybisbenzyl alcohol from Agaricus subrutilescens and its inhibitory activity against bacterial biofilm formation
Jewel C De Padua, Tomoya Tanaka, Kotomi Ueno, Thomas Edison E dela Cruz, Atsushi Ishihara
Bioscience, Biotechnology, and Biochemistry.2024; 88(9): 983. CrossRef
Control of Staphylococcus epidermidis biofilm by surfactins of an endophytic bacterium Bacillus sp. 15 F
Marwa Jardak, Raphaël Lami, Oumaima Saadaoui, Hajer Jlidi, Didier Stien, Sami Aifa, Sami Mnif
Enzyme and Microbial Technology.2024; 180: 110477. CrossRef
A concise review of the effect of efflux pump on biofilm intensity in bacteria with a special view to Mycobacterium
Marjan Darbani Fouladi, Saeid Besharati, Parissa Farnia, Adnan Khosravi
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine.2024; 3(1): 1. CrossRef
Translating bacteriophage-derived depolymerases into antibacterial therapeutics: Challenges and prospects
Honglan Wang, Yannan Liu, Changqing Bai, Sharon Shui Yee Leung
Acta Pharmaceutica Sinica B.2024; 14(1): 155. CrossRef
Modulation of proteins by rare earth elements as a biotechnological tool
Azam Bakhti, Zahra Shokouhi, Fatemeh Mohammadipanah
International Journal of Biological Macromolecules.2024; 258: 129072. CrossRef
Antibiofilm Strategies in Neonatal and Pediatric Infections
Chrysoula Kosmeri, Vasileios Giapros, Anastasios Serbis, Foteini Balomenou, Maria Baltogianni
Antibiotics.2024; 13(6): 509. CrossRef
In vitro anti-bactrical activity and its preliminary mechanism of action of the non-medicinal parts of Sanguisorba officinalis L. against Helicobacter pylori infection
Pengting Chen, Meiyun Chen, Chang Peng, Jiahui Yan, Xue Shen, Weijia Zhang, Yuemei Yuan, Guoxing Gan, Xiaojun Luo, Weixing Zhu, Meicun Yao
Journal of Ethnopharmacology.2024; 318: 116981. CrossRef
Delving into the Mechanisms of Sponge-Associated Enterobacter against Staphylococcal Biofilms
Anna Luiza Bauer Canellas, Bruno Francesco Rodrigues de Oliveira, Suzanne de Oliveira Nunes, Camila Adão Malafaia, Ana Claudia F. Amaral, Daniel Luiz Reis Simas, Ivana Correa Ramos Leal, Marinella Silva Laport
Molecules.2023; 28(12): 4843. CrossRef
A new approach to overcoming antibiotic-resistant bacteria: Traditional Chinese medicine therapy based on the gut microbiota
Peng Xue, Rui Sang, Nan Li, Siyuan Du, Xiuwen Kong, Mingliang Tai, Zhihao Jiang, Ying Chen
Frontiers in Cellular and Infection Microbiology.2023;[Epub] CrossRef
Molybdenum oxide nanotube caps decorated with ultrafine Ag nanoparticles: Synthesis and antimicrobial activity
Shabnam Yavari, Kayode Olaifa, Darya Shafiee, Reza Rasuli, Mehdi Shafiee
International Journal of Pharmaceutics.2023; 647: 123528. CrossRef
Bacterial biofilm inhibitors: An overview
Vipin Chandra Kalia, Sanjay K.S. Patel, Jung-Kul Lee
Ecotoxicology and Environmental Safety.2023; 264: 115389. CrossRef
Better together– Salmonella biofilm-associated antibiotic resistance
Adrianna Aleksandrowicz, Ewa Carolak, Agata Dutkiewicz, Aleksandra Błachut, Wiktoria Waszczuk, Krzysztof Grzymajlo
Gut Microbes.2023;[Epub] CrossRef
Natural Medicine a Promising Candidate in Combating Microbial Biofilm
Athar Shamim, Asgar Ali, Zeenat Iqbal, Mohd Aamir Mirza, Mohd Aqil, S. M. Kawish, Ayesha Siddiqui, Vijay Kumar, Punnoth Poonkuzhi Naseef, Abdulkhaliq Ali F. Alshadidi, Mohamed Saheer Kuruniyan
Antibiotics.2023; 12(2): 299. CrossRef
Antibiotic Resistance and Biofilm Infections in the NICUs and Methods to Combat It
Maria Baltogianni, Vasileios Giapros, Chrysoula Kosmeri
Antibiotics.2023; 12(2): 352. CrossRef
In vitro activity of sanitizers against mono- and polymicrobial biofilms of C. parapsilosis and S. aureus
Vitor de Paula Castro, Danilo Yamamoto Thomaz, Kayro de Lima Vieira, Leonardo Guedes Lopes, Flavia Rossi, Gilda M. B. Del Negro, Gil Benard, Regina Helena Pires, Andreas H. Groll
Antimicrobial Agents and Chemotherapy.2023;[Epub] CrossRef
Inhibition of bacterial biofilms by the snake venom proteome
Neyaz A. Khan, Fernanda G. Amorim, John P. Dunbar, Dayle Leonard, Damien Redureau, Loïc Quinton, Michel M. Dugon, Aoife Boyd
Biotechnology Reports.2023; 39: e00810. CrossRef
Compounds That Have an Anti-Biofilm Effect against Common Bacteria at Very Low Concentrations and Their Antibiotic Combination Effect
Hyeon-Ji Hwang, Dan-dan Li, Jieun Lee, Min Kyung Kang, Hyung Ryong Moon, Joon-Hee Lee
Antibiotics.2023; 12(5): 853. CrossRef
Biofilm-Producing Ability of Staphylococcus aureus Obtained from Surfaces and Milk of Mastitic Cows
Mária Vargová, František Zigo, Jana Výrostková, Zuzana Farkašová, Ibrahim F. Rehan
Veterinary Sciences.2023; 10(6): 386. CrossRef
Utilization of Existing Human Kinase Inhibitors as Scaffolds in the Development of New Antimicrobials
Monika I. Konaklieva, Balbina J. Plotkin
Antibiotics.2023; 12(9): 1418. CrossRef
Synergistic action of phages and lytic proteins with antibiotics: a combination strategy to target bacteria and biofilms
Han Lu, Zong Li, Amro Elbaz, Shou-Qing Ni
BMC Microbiology.2023;[Epub] CrossRef
Consolidated knowledge-guided computational pipeline for therapeutic intervention against bacterial biofilms - a review
Reetika Debroy, Sudha Ramaiah
Biofouling.2023; 39(9-10): 928. CrossRef
Molecular identification of a novel antimicrobial peptide in giant Triton snail Charonia tritonis: mRNA profiles for tissues and its potential antibacterial activity
Xitong Cen, Bing Liu, Gege Zhang, Huiru Liu, Gaoyou Yao, Maoxian He, Wenguang Liu
Fish & Shellfish Immunology.2023; 136: 108734. CrossRef
Effect of a Depolymerase Encoded by Phage168 on a Carbapenem-Resistant Klebsiella pneumoniae and Its Biofilm
Xu Sun, Bingchun Pu, Jinhong Qin, Jun Xiang
Pathogens.2023; 12(12): 1396. CrossRef
In Vitro Antibiofilm Activity of Resveratrol against Aeromonas hydrophila
Ting Qin, Kai Chen, Bingwen Xi, Liangkun Pan, Jun Xie, Liushen Lu, Kai Liu
Antibiotics.2023; 12(4): 686. CrossRef
Sodium Octanoate–Functionalized Chitosan Coating Reduces Dry Rot Caused by Fusarium Sambucinum (AUC-TZ-1) in Potato Minitubers in Storage
Rafael Jiménez-Mejía, Mariana Corona-Márquez, Jessica G. Zepeda-García, Cristina Rodríguez-Cárdenas, Gustavo Santoyo, Luzmaría R. Morales-Cedeño, Ricardo I. Medina-Estrada, Mónica G. Sánchez-Ceja, Pedro D. Loeza-Lara
Potato Research.2023; 66(4): 1059. CrossRef
Combined antimicrobial effect of phage-derived endolysin and depolymerase against biofilm-forming Salmonella Typhimurium
Junhwan Kim, Jun Wang, Juhee Ahn
Biofouling.2023; 39(7): 763. CrossRef
Influences of flavonoids from Sedum aizoon L. on biofilm formation of Pseudomonas fragi
Haoxia Wang, Qingqing Ge, Xingfeng Shao, Yingying Wei, Xin Zhang, Hongfei Wang, Feng Xu
Applied Microbiology and Biotechnology.2023; 107(11): 3687. CrossRef
Antibacterial and antibiofilm potential of Lacticaseibacillus rhamnosus YT and its cell-surface extract
Chengran Guan, Wenjuan Zhang, Jianbo Su, Feng Li, Dawei Chen, Xia Chen, Yujun Huang, Ruixia Gu, Chenchen Zhang
BMC Microbiology.2023;[Epub] CrossRef
From Antibacterial to Antibiofilm Targeting: An Emerging Paradigm Shift in the Development of Quaternary Ammonium Compounds (QACs)
Evgeniya A. Saverina, Nikita A. Frolov, Olga A. Kamanina, Vyacheslav A. Arlyapov, Anatoly N. Vereshchagin, Valentine P. Ananikov
ACS Infectious Diseases.2023; 9(3): 394. CrossRef
Acinetobacter baumannii biofilm and its potential therapeutic targets
Eman Abdelbaset Mohamed, Marwa M. Raafat, Reham Samir Mohamed, Amal Emad Eldin Ali
Future Journal of Pharmaceutical Sciences.2023;[Epub] CrossRef
Control of pathogenic bacteria using marine actinobacterial extract with antiquorum sensing and antibiofilm activity
Marco Wijaya, Dea Delicia, Diana Elizabeth Waturangi
BMC Research Notes.2023;[Epub] CrossRef
Synthetic non-toxic anti-biofilm agents as a strategy in combating bacterial resistance
Rasha Mohamed Hassan, Mohamed Samir Abd El-Maksoud, Iman Ahmed Youssef Ghannam, Aida Abdel- Sattar El-Azzouny, Mohamed Nabil Aboul-Enein
European Journal of Medicinal Chemistry.2023; 262: 115867. CrossRef
Isolation and characterization of SGF3, a novel Microviridae phage infecting Shigella flexneri
Han Lu, Wenbin Xiong, Zong Li, Peihan Yan, Ruyin Liu, Xinchun Liu
Molecular Genetics and Genomics.2022; 297(4): 935. CrossRef
Phytocompound Mediated Blockage of Quorum Sensing Cascade in ESKAPE Pathogens
Sreejita Ghosh, Dibyajit Lahiri, Moupriya Nag, Ankita Dey, Soumya Pandit, Tanmay Sarkar, Siddhartha Pati, Zulhisyam Abdul Kari, Ahmad Razali Ishak, Hisham Atan Edinur, Rina Rani Ray
Antibiotics.2022; 11(1): 61. CrossRef
Enhanced sunlight-absorption of Fe2O3 covered by PANI for the photodegradation of organic pollutants and antimicrobial inactivation
Faisal Mukhtar, Tauseef Munawar, Muhammad Shahid Nadeem, Shoukat Alim Khan, Muammer Koc, Sana Batool, Murtaza Hasan, Faisal Iqbal
Advanced Powder Technology.2022; 33(8): 103708. CrossRef
Borrelia burgdorferi Co-Localizing with Amyloid Markers in Alzheimer’s Disease Brain Tissues
Alireza G. Senejani, Jasmin Maghsoudlou, Dina El-Zohiry, Gauri Gaur, Keith Wawrzeniak, Cristina Caravaglia, Vishwa A. Khatri, Alan MacDonald, Eva Sapi
Journal of Alzheimer's Disease.2022; 85(2): 889. CrossRef
Advanced Strategies of Enzyme Activity Regulation for Biomedical Applications
Zihan Chen, Yu Zhao, Yang Liu
ChemBioChem.2022;[Epub] CrossRef
Mode of action of elasnin as biofilm formation eradicator of methicillin-resistant Staphylococcus aureus
Lexin Long, Jordy Evan Sulaiman, Yao Xiao, Aifang Cheng, Ruojun Wang, Jessie James Malit, Wai Chuen Wong, Wenchao Liu, Yong-Xin Li, Feng Chen, Henry Lam, Pei-Yuan Qian
Frontiers in Microbiology.2022;[Epub] CrossRef
In silico disrupting quorum sensing of porphyromonas gingivalis via essential oils and coumarin derivatives
Al-Madhagi Haitham Ahmed, Tahan Zaher Samman
Annals of Proteomics and Bioinformatics.2022; 6(1): 001. CrossRef
Nitric oxide-releasing L-Tryptophan and L-Phenylalanine based Poly(ester urea)s electrospun composite mats as antibacterial and antibiofilm dressing for wound healing
Mengna Li, Weiwang Qiu, Qian Wang, Na Li, Xueli Wang, Jianyong Yu, Xiaoran Li, Faxue Li, Dequn Wu
Composites Part B: Engineering.2022; 229: 109484. CrossRef
Nitric Oxide-Releasing Tryptophan-Based Poly(ester urea)s Electrospun Composite Nanofiber Mats with Antibacterial and Antibiofilm Activities for Infected Wound Healing
Mengna Li, Weiwang Qiu, Qian Wang, Na Li, Lu Liu, Xueli Wang, Jianyong Yu, Xiaoran Li, Faxue Li, Dequn Wu
ACS Applied Materials & Interfaces.2022; 14(14): 15911. CrossRef
Recent Strategies to Combat Biofilms Using Antimicrobial Agents and Therapeutic Approaches
Looniva Shrestha, Hai-Ming Fan, Hui-Ren Tao, Jian-Dong Huang
Pathogens.2022; 11(3): 292. CrossRef
Activity of Antibiotics and Potential Antibiofilm Agents against Biofilm-Producing Mycobacterium avium-intracellulare Complex Causing Chronic Pulmonary Infections
Elena Portell-Buj, Cecibel González-Criollo, Alexandre López-Gavín, Mariana Fernández-Pittol, Maria Antònia Busquets, Joan Estelrich, Montserrat Garrigó, Marc Rubio, Griselda Tudó, Julian Gonzalez-Martin
Antibiotics.2022; 11(5): 589. CrossRef
Supermagnetic halloysite nanotubes surface-tuned with aminosilane for protease immobilization and applied for eradication of bacterial biofilm
Min Kim, Min Kyoung Shin, Jung-Suk Sung, Avinash A. Kadam
Applied Surface Science.2022; 593: 153469. CrossRef
Biofilms as a microbial hazard in the food industry: A scoping review
Manjeet Sharan, Deepthi Vijay, Pankaj Dhaka, Jasbir Singh Bedi, Jatinder Paul Singh Gill
Journal of Applied Microbiology.2022; 133(4): 2210. CrossRef
Enhanced inactivation of Salmonella enterica Enteritidis biofilms on the stainless steel surface by proteinase K in the combination with chlorine
Min-Jeong Kim, Joo-Sung Kim
Food Control.2022; 132: 108519. CrossRef
Phylogenetic identification of fungi isolated from strawberry and papaya fruits and their susceptibility to fatty acids
Leticia Robles-Yerena, Johan Rodríguez-Mendoza, Gustavo Santoyo, Xavier Iván Ochoa-Alvarado, Ricardo Ivan Medina-Estrada, Rafael Jiménez-Mejía, Pedro Damián Loeza-Lara
Canadian Journal of Plant Pathology.2022; 44(6): 828. CrossRef
New insights into the inhibitory roles and mechanisms of D-amino acids in bacterial biofilms in medicine, industry, and agriculture
Saeed Niazi Vahdati, Hossein Behboudi, Sepideh Aliniaye Navasatli, Sara Tavakoli, Maliheh Safavi
Microbiological Research.2022; 263: 127107. CrossRef
Synergistic combination of malic acid with sodium hypochlorite impairs biofilm of Cronobacter sakazakii
Rajni Chauhan, Savita Kumari, Gunjan Goel, Wamik Azmi
LWT.2022; 155: 112902. CrossRef
Marine natural products and their synthetic analogs as promising antibiofilm agents for antibiotics discovery and development
Yueting Deng, Yang Liu, Juan Li, Xiao Wang, Shan He, Xiaojun Yan, Yutong Shi, Weiyan Zhang, Lijian Ding
European Journal of Medicinal Chemistry.2022; 239: 114513. CrossRef
Antimicrobial activities of 1-phenyl-3-methyl-4-trichloroacetyl-pyrazolone: Experimental, DFT studies, and molecular docking investigation
Ededet A. Eno, Justina I. Mbonu, Hitler Louis, Faith S. Patrick-Inezi, Terkumbur E. Gber, Tomsmith O. Unimuke, Emmanuel E.D. Okon, Innocent Benjamin, Offiong E. Offiong
Journal of the Indian Chemical Society.2022; 99(7): 100524. CrossRef
Antibiofilm Effects of Bacteriocin BMP32r on Listeria monocytogenes
Zhu Qiao, Leshan Zhang, Xin Wang, Bianfang Liu, Yuanyuan Shan, Yanglei Yi, Yuan Zhou, Xin Lü
Probiotics and Antimicrobial Proteins.2022; 14(6): 1067. CrossRef
NO donors and NO delivery methods for controlling biofilms in chronic lung infections
Yu-Ming Cai, Ying-Dan Zhang, Liang Yang
Applied Microbiology and Biotechnology.2021; 105(10): 3931. CrossRef
Enzyme Therapy: Current Challenges and Future Perspectives
Miguel de la Fuente, Laura Lombardero, Alfonso Gómez-González, Cristina Solari, Iñigo Angulo-Barturen, Arantxa Acera, Elena Vecino, Egoitz Astigarraga, Gabriel Barreda-Gómez
International Journal of Molecular Sciences.2021; 22(17): 9181. CrossRef
Antibiofilm Activity of Gallium(III) Complexed Anionic Polymers in Combination with Antibiotics
Jielin Ma, Shuai Hou, Mary B. Chan‐Park, Hongwei Duan
Macromolecular Rapid Communications.2021;[Epub] CrossRef
Pseudomonas aeruginosa Biofilm Formation and Its Control
Aishwarya Vetrivel, Monica Ramasamy, Preethi Vetrivel, Santhi Natchimuthu, Shobana Arunachalam, Gon-Sup Kim, Rajeswari Murugesan
Biologics.2021; 1(3): 312. CrossRef
Dynamic Constitutional Frameworks as Antibacterial and Antibiofilm Agents
Andrei Diaconu, Tom Coenye, Mihail Barboiu, Stéphane P. Vincent
Angewandte Chemie International Edition.2021; 60(41): 22505. CrossRef
Identification of Bioactive Compounds and Evaluation of the Antimicrobial and Anti-biofilm Effect of Psammocinia sp. and Hyattella sp. Sponges from the Persian Gulf
Homa Hamayeli, Mehdi Hassanshahian, Majid Askari Hesni
Thalassas: An International Journal of Marine Sciences.2021; 37(1): 357. CrossRef
Antibacterial peptides from seafood: A promising weapon to combat bacterial hazards in food
Jinrong Tong, Zhaohuan Zhang, Qian Wu, Zhenhua Huang, Pradeep K. Malakar, Liangbiao Chen, Haiquan Liu, Yingjie Pan, Yong Zhao
Food Control.2021; 125: 108004. CrossRef
Discovery of Polyvalent Myovirus (vB_STM-2) Phage as a Natural Antimicrobial System to Lysis and Biofilm Removal of Salmonella Typhimurium Isolates from Various Food Sources
Iman M. A. Abdelhadi, Ahmed R. Sofy, Ahmed A. Hmed, Ehab E. Refaey, Hany E. Soweha, Mohamed A. Abbas
Sustainability.2021; 13(21): 11602. CrossRef
Phytochemical Composition, Antibacterial, and Antibiofilm Activity of Malva sylvestris Against Human Pathogenic Bacteria
Mahmoud Fathi, Maryam Ghane, Leila Pishkar
Jundishapur Journal of Natural Pharmaceutical Products.2021;[Epub] CrossRef
Bacteriophage-Derived Depolymerases against Bacterial Biofilm
Gracja Topka-Bielecka, Aleksandra Dydecka, Agnieszka Necel, Sylwia Bloch, Bożena Nejman-Faleńczyk, Grzegorz Węgrzyn, Alicja Węgrzyn
Antibiotics.2021; 10(2): 175. CrossRef
Inhibitory Effects of Cinnamaldehyde Derivatives on Biofilm Formation and Virulence Factors in Vibrio Species
Olajide Sunday Faleye, Ezhaveni Sathiyamoorthi, Jin-Hyung Lee, Jintae Lee
Pharmaceutics.2021; 13(12): 2176. CrossRef
In Vitro Effect of Copper (I) Complex [Cu(NN1)2](ClO4) on Vibrio harveyi BB170 Biofilm Formation
Sarita Soto-Aguilera, Brenda Modak, Maialen Aldabaldetrecu, Carla P. Lozano, Juan Guerrero, Claudia Lefimil, Mick Parra
Microorganisms.2021; 9(11): 2273. CrossRef
Dynamic Constitutional Frameworks as Antibacterial and Antibiofilm Agents
Andrei Diaconu, Tom Coenye, Mihail Barboiu, Stéphane P. Vincent
Angewandte Chemie.2021; 133(41): 22679. CrossRef
Antibacterial, anti-biofilm and anti-quorum sensing activities of Artemisia dracunculus essential oil (EO): a study against Salmonella enterica serovar Typhimurium and Staphylococcus aureus
Shima Mohammadi Pelarti, Leila Karimi Zarehshuran, Laleh Babaeekhou, Maryam Ghane
Archives of Microbiology.2021; 203(4): 1529. CrossRef
Bacterial Biofilm Destruction: A Focused Review On The Recent Use of Phage-Based Strategies With Other Antibiofilm Agents
Stephen Amankwah, Kedir Abdusemed, Tesfaye Kassa
Nanotechnology, Science and Applications.2021; Volume 14: 161. CrossRef
The Chemistry of Antibiofilm Phytocompounds
Dibyajit Lahiri, Moupriya Nag, Sayantani Garai, Rina Rani Ray
Mini-Reviews in Medicinal Chemistry.2021; 21(9): 1034. CrossRef
Synergistic Activity of Equol and Meropenem against Carbapenem-Resistant Escherichia coli
Hye-Rim Kim, Yong-Bin Eom
Antibiotics.2021; 10(2): 161. CrossRef
Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies
Muzamil Ahmad Rather, Kuldeep Gupta, Manabendra Mandal
Brazilian Journal of Microbiology.2021; 52(4): 1701. CrossRef
Synthesis and antimicrobial evaluation of a pyrazoline-pyridine silver(I) complex: DNA-interaction and anti-biofilm activity
Dimitris Matiadis, Maria Karagiaouri, Barbara Mavroidi, Katarzyna E. Nowak, Georgios Katsipis, Maria Pelecanou, Anastasia Pantazaki, Marina Sagnou
BioMetals.2021; 34(1): 67. CrossRef
Multi-purpose Disinfecting Solutions only Partially Inhibit the Development of Ocular Microbes Biofilms in Contact Lens Storage Cases
Fabiano B.M. de Araújo, Vinicius C. Morais, Bianca T.M. de Oliveira, Kaíque Y.G. de Lima, Victor T. Gomes, Ian P.G. do Amaral, Ulrich Vasconcelos
Middle East African Journal of Ophthalmology.2021; 28(2): 116. CrossRef
Activity of Liquid and Volatile Fractions of Essential Oils against Biofilm Formed by Selected Reference Strains on Polystyrene and Hydroxyapatite Surfaces
Ruth Dudek-Wicher, Justyna Paleczny, Beata Kowalska-Krochmal, Patrycja Szymczyk-Ziółkowska, Natalia Pachura, Antoni Szumny, Malwina Brożyna
Pathogens.2021; 10(5): 515. CrossRef
Antibacterial and antibiofilm activities of diphyllin against fish pathogens
Suman Thamburaj, Elangomathavan Ramaraj, Sivasamy Sethupathy, Chakkaravarthi Kamalanathan, Atchudan Raji, Satish Kumar Rajasekharan
Microbial Pathogenesis.2020; 145: 104232. CrossRef
The Role of Bacterial Biofilm in Antibiotic Resistance and Food Contamination
Gedif Meseret Abebe
International Journal of Microbiology.2020; 2020: 1. CrossRef
The use of papain for the removal of biofilms formed by pathogenic Staphylococcus aureus and Campylobacter jejuni
Ye Ji Song, Hwan Hee Yu, Yeon Jin Kim, Na-Kyoung Lee, Hyun-Dong Paik
LWT.2020; 127: 109383. CrossRef
Biofilm inhibition and mode of action of epigallocatechin gallate against Vibrio mimicus
Rui Li, Jieyuan Lu, Hebo Duan, Jun Yang, Changbo Tang
Food Control.2020; 113: 107148. CrossRef
Structural approaches to pathway-specific antimicrobial agents
Michael E. Johnson, Leslie W.-M. Fung
Translational Research.2020; 220: 114. CrossRef
Study on the effects of different dimerization positions on biological activity of partial d-Amino acid substitution analogues of Anoplin
Chao Zhong, Sanhu Gou, Tianqi Liu, Yuewen Zhu, Ningyi Zhu, Hui Liu, Yun Zhang, Junqiu Xie, Xiaomin Guo, Jingman Ni
Microbial Pathogenesis.2020; 139: 103871. CrossRef
Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance
Stella Cascioferro, Barbara Parrino, Daniela Carbone, Domenico Schillaci, Elisa Giovannetti, Girolamo Cirrincione, Patrizia Diana
Journal of Medicinal Chemistry.2020; 63(15): 7923. CrossRef
Alterocin, an Antibiofilm Protein Secreted by Pseudoalteromonas sp. Strain 3J6
Albane Jouault, Angélique Gobet, Marjolaine Simon, Emilie Portier, Morgan Perennou, Erwan Corre, Fanny Gaillard, David Vallenet, Gurvan Michel, Yannick Fleury, Alexis Bazire, Alain Dufour, Andrew J. McBain
Applied and Environmental Microbiology.2020;[Epub] CrossRef
Thermoregulation of Pseudomonas aeruginosa Biofilm Formation
Suran Kim, Xi-Hui Li, Hyeon-Ji Hwang, Joon-Hee Lee, Danilo Ercolini
Applied and Environmental Microbiology.2020;[Epub] CrossRef
Scientific evidence in antimicrobial photodynamic therapy: An alternative approach for reducing cariogenic bacteria
Ana Catarina Martins Reis, Wanessa Fernandes Matias Regis, Lidiany Karla Azevedo Rodrigues
Photodiagnosis and Photodynamic Therapy.2019; 26: 179. CrossRef
Triterpene Derivatives as Relevant Scaffold for New Antibiofilm Drugs
Gloria Narjara Santos da Silva, Muriel Primon-Barros, Alexandre José Macedo, Simone Cristina Baggio Gnoatto
Biomolecules.2019; 9(2): 58. CrossRef
Characterization and Genome Analysis of Staphylococcus aureus Podovirus CSA13 and Its Anti-Biofilm Capacity
Yoyeon Cha, Jihwan Chun, Bokyung Son, Sangryeol Ryu
Viruses.2019; 11(1): 54. CrossRef
Effective removal of staphylococcal biofilms on various food contact surfaces by Staphylococcus aureus phage endolysin LysCSA13
Yoyeon Cha, Bokyung Son, Sangryeol Ryu
Food Microbiology.2019; 84: 103245. CrossRef
Bacteria‐Targeted Supramolecular Photosensitizer Delivery Vehicles for Photodynamic Ablation Against Biofilms
Yifan Gao, Jing Wang, Dengfeng Hu, Yongyan Deng, Tingting Chen, Qiao Jin, Jian Ji
Macromolecular Rapid Communications.2019;[Epub] CrossRef
The Varied Role of Efflux Pumps of the MFS Family in the Interplay of Bacteria with Animal and Plant Cells
Martina Pasqua, Milena Grossi, Alessandro Zennaro, Giulia Fanelli, Gioacchino Micheli, Frederic Barras, Bianca Colonna, Gianni Prosseda
Microorganisms.2019; 7(9): 285. CrossRef
Developing natural products as potential anti-biofilm agents
Lan Lu, Wei Hu, Zeru Tian, Dandan Yuan, Guojuan Yi, Yangyang Zhou, Qiang Cheng, Jie Zhu, Mingxing Li
Chinese Medicine.2019;[Epub] CrossRef
A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes
Maria Grazia Cusimano, Angelo Spinello, Giampaolo Barone, Domenico Schillaci, Stella Cascioferro, Alessandra Magistrato, Barbara Parrino, Vincenzo Arizza, Maria Vitale
Marine Drugs.2019; 17(3): 159. CrossRef
A Consideration of Antibacterial Agent Efficacies in the Treatment and Prevention of Formation of Staphylococcus aureus Biofilm
Zahra Sedarat, Andrew W. Taylor-Robinson
Journal of Microbiology and Infectious Diseases.2019; : 167. CrossRef
Biofilm Disruption Utilizing α/β Chimeric Polypeptide Molecular Brushes
Si Zhang, Xi-Mian Xiao, Fan Qi, Peng-Cheng Ma, Wei-Wei Zhang, Cheng-Zhi Dai, Dan-Feng Zhang, Run-Hui Liu
Chinese Journal of Polymer Science.2019; 37(11): 1105. CrossRef
Perspectives towards antibiotic resistance: from molecules to population
Joon-Hee Lee
Journal of Microbiology.2019; 57(3): 181. CrossRef
Nanoantibiotics: A Novel Rational Approach to Antibiotic Resistant Infections
Ayse Basak Engin, Atilla Engin
Current Drug Metabolism.2019; 20(9): 720. CrossRef
Targeting the Pseudomonas quinolone signal quorum sensing system for the discovery of novel anti-infective pathoblockers
Christian Schütz, Martin Empting
Beilstein Journal of Organic Chemistry.2018; 14: 2627. CrossRef
Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa
Donghoon Kang, Natalia V. Kirienko
Journal of Microbiology.2018; 56(7): 449. CrossRef
Intrapulmonary percussive ventilation improves lung function in cystic fibrosis patients chronically colonized with Pseudomonas aeruginosa: a pilot cross-over study
Jozef Dingemans, Hanneke Eyns, Julie Willekens, Pieter Monsieurs, Rob Van Houdt, Pierre Cornelis, Anne Malfroot, Aurélie Crabbé
European Journal of Clinical Microbiology & Infectious Diseases.2018; 37(6): 1143. CrossRef
Dysbiosis, small intestinal bacterial overgrowth and biofilms in autism and chronic illness
Anju Usman Singh
AIMS Molecular Science.2018; 5(2): 160. CrossRef
Antibiofilm effect of biofilm-dispersing agents on clinical isolates of Pseudomonas aeruginosa with various biofilm structures
Soo-Kyoung Kim, Xi-Hui Li, Hyeon-Ji Hwang, Joon-Hee Lee
Journal of Microbiology.2018; 56(12): 902. CrossRef
Control of Biofilm Formation in Healthcare: Recent Advances Exploiting Quorum-Sensing Interference Strategies and Multidrug Efflux Pump Inhibitors
Bindu Subhadra, Dong Ho Kim, Kyungho Woo, Surya Surendran, Chul Hee Choi
Materials.2018; 11(9): 1676. CrossRef
Printing of Patterned, Engineered E. coli Biofilms with a Low-Cost 3D Printer
Dominik T. Schmieden, Samantha J. Basalo Vázquez, Héctor Sangüesa, Marit van der Does, Timon Idema, Anne S. Meyer
ACS Synthetic Biology.2018; 7(5): 1328. CrossRef
Thinking Outside the Box—Novel Antibacterials To Tackle the Resistance Crisis
Markus Lakemeyer, Weining Zhao, Franziska A. Mandl, Peter Hammann, Stephan A. Sieber
Angewandte Chemie International Edition.2018; 57(44): 14440. CrossRef
Über bisherige Denkweisen hinaus – neue Wirkstoffe zur Überwindung der Antibiotika‐Krise
Markus Lakemeyer, Weining Zhao, Franziska A. Mandl, Peter Hammann, Stephan A. Sieber
Angewandte Chemie.2018; 130(44): 14642. CrossRef
Diabetic foot infection: A critical complication
Jennifer J Hurlow, Gavin J Humphreys, Frank L Bowling, Andrew J McBain
International Wound Journal.2018; 15(5): 814. CrossRef
Bacterial Biofilm Inhibition in the Development of Effective Anti-Virulence Strategy
Barbara Parrino, Patrizia Diana, Girolamo Cirrincione, Stella Cascioferro
The Open Medicinal Chemistry Journal.2018; 12(1): 84. CrossRef
Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization
Carolina Pasero, Ilaria D’Agostino, Filomena De Luca, Claudio Zamperini, Davide Deodato, Giuseppina I. Truglio, Filomena Sannio, Rosita Del Prete, Teresa Ferraro, Daniela Visaggio, Arianna Mancini, Mario B. Guglielmi, Paolo Visca, Jean-Denis Docquier, Mau
Journal of Medicinal Chemistry.2018; 61(20): 9162. CrossRef
Potent effects of amino acid scanned antimicrobial peptide Feleucin-K3 analogs against both multidrug-resistant strains and biofilms of Pseudomonas aeruginosa
Junqiu Xie, Yao Li, Jing Li, Zhibin Yan, Dan Wang, Xiaomin Guo, Jianfeng Zhang, Bangzhi Zhang, Lingyun Mou, Wenle Yang, Xianxing Jiang
Amino Acids.2018; 50(10): 1471. CrossRef

MINIREVIEW] Biofilm dispersion in Pseudomonas aeruginosa: Soo-Kyoung Kim , Joon-Hee Lee; J. Microbiol. 2016;54(2):71-85. Published online February 2, 2016; DOI: https://doi.org/10.1007/s12275-016-5528-7

54 View
0 Download
85 Crossref

Abstract

In recent decades, many researchers have written numerous articles about microbial biofilms. Biofilm is a complex community of microorganisms and an example of bacterial group behavior. Biofilm is usually considered a sessile mode of life derived from the attached growth of microbes to surfaces, and most biofilms are embedded in self-produced extracellular matrix composed of extracellular polymeric substances (EPSs), such as polysaccharides, extracellular DNAs (eDNA), and proteins. Dispersal, a mode of biofilm detachment indicates active mechanisms that cause individual cells to separate from the biofilm and return to planktonic life. Since biofilm cells are cemented and surrounded by EPSs, dispersal is not simple to do and many researchers are now paying more attention to this active detachment process. Unlike other modes of biofilm detachment such as erosion or sloughing, which are generally considered passive processes, dispersal occurs as a result of complex spatial differentiation and molecular events in biofilm cells in response to various environmental cues, and there are many biological reasons that force bacterial cells to disperse from the biofilms. In this review, we mainly focus on the spatial differentiation of biofilm that is a prerequisite for dispersal, as well as environmental cues and molecular events related to the biofilm dispersal. More specifically, we discuss the dispersal-related phenomena and mechanisms observed in Pseudomonas aeruginosa, an important opportunistic human pathogen and representative model organism for biofilm study.

Citations

Citations to this article as recorded by

Accumulated temperature dictates the regional structural variation of prokaryotic periphyton at soil-water interface in paddy fields
Pengfei Sun, Kunkun Fan, Yuji Jiang, Haiyan Chu, Yin Chen, Yonghong Wu
Water Research.2024; 265: 122259. CrossRef
Imbalanced intracellular nutrient stoichiometries drive the regional structural variation of microeukaryotic communities in paddy fields
Pengfei Sun, Eleonora Silvano, Yin Chen, Yonghong Wu
ISME Communications.2024;[Epub] CrossRef
New Alpiniamide‐Type Polyketide with Antibiofilm Activities from the Marine‐Derived Streptomyces sp. ZS‐A65
Fanqi Pu, Jiebin Fang, Wenshuo Li, Bin Zhang, Xinyi Hong, Lei Xu, Xihui Li, Yongjun Jiang
Chemistry & Biodiversity.2024;[Epub] CrossRef
In vitro inhibition of Pseudomonas aeruginosa PAO1 biofilm formation by DZ2002 through regulation of extracellular DNA and alginate production
Jiaze Dai, Wenying Luo, Fei Hu, Si Li
Frontiers in Cellular and Infection Microbiology.2024;[Epub] CrossRef
A bacterial sense of touch: T4P retraction motor as a means of surface sensing by Pseudomonas aeruginosa PA14
C. J. Geiger, G. C. L. Wong, G. A. O'Toole, Michael Y. Galperin
Journal of Bacteriology.2024;[Epub] CrossRef
Micro-biophysical interactions at bacterium-mineral interfaces determine potassium dissolution
Miao Han, Xiaoyan Zhu, Chujin Ruan, Hanqing Wu, Guowei Chen, Kun Zhu, Ying Liu, Gang Wang
Environmental Technology & Innovation.2024; 33: 103524. CrossRef
Decoding the influence of low temperature on biofilm development: The hidden roles of c-di-GMP
Yu-Ting Lin, Yong-Chao Wang, Yi-Mei Xue, Zhen Tong, Guan-Yu Jiang, Xu-Rui Hu, John C. Crittenden, Can Wang
Science of The Total Environment.2024; 927: 172376. CrossRef
Screening and functional characterization of isocitrate lyase AceA in the biofilm formation of Vibrio alginolyticus
Weibo Shi, Ya Li, Weiwei Zhang, Jennifer F. Biddle
Applied and Environmental Microbiology.2024;[Epub] CrossRef
Acinetobacter baumannii as an oro-dental pathogen: a red alert!!
A. S. Smiline GIRIJA
Journal of Applied Oral Science.2024;[Epub] CrossRef
Vitamin D and vitamin K1 as novel inhibitors of biofilm in Gram-negative bacteria
Lekaa L. Lutfi, Mona I. Shaaban, Soha Lotfy Elshaer
BMC Microbiology.2024;[Epub] CrossRef
The effect of antibacterial peptide ε-Polylysine against Pseudomonas aeruginosa biofilm in marine environment
Siwei Wu, Quantong Jiang, Dongzhu Lu, Xiaofan Zhai, Jizhou Duan, Baorong Hou
npj Materials Degradation.2024;[Epub] CrossRef
Determination of biofilm formation, antibiotic susceptibility profiles and quorum sensing mediated virulence factors in ceftazidime resistant Pseudomonas aeruginosa
Ceren Başkan, Tuba Yıldırım, Melek Bilgin, Hülya Sivas
Biologia.2023; 78(10): 2881. CrossRef
Pharmacological Characters and Toxicity Evaluation of Coumarin Derivative LP4C as Lead Compound against Biofilm Formation of Pseudomonas aeruginosa
Moxi Yu, Jiajia Xin, Yongsheng Liu, Yamiao Chen, Hui Zhao, Yaoyao Li, Yachen Hou, Min Jia, Bin Wang, Mingkai Li
Molecules.2023; 28(7): 3138. CrossRef
Overview of the effects and mechanisms of NO and its donors on biofilms
Yanan Tian, Xiaojing Tian, Teng Li, Wenhang Wang
Critical Reviews in Food Science and Nutrition.2023; : 1. CrossRef
Respiratory culture organism isolation and test characteristics in children with tracheostomies with and without acute respiratory infection
Rebecca Steuart, Guillermo B. Ale, Abigail Woolums, Nicole Xia, Dan Benscoter, Christopher J. Russell, Samir S. Shah, Joanna Thomson
Pediatric Pulmonology.2023; 58(5): 1481. CrossRef
Exopolysaccharide produced by Lactiplantibacillus plantarum Y12 exhibits inhibitory effect on the Shigella flexneri genes expression related to biofilm formation
Yinglong Song, Mengying Sun, Guangqing Mu, Yanfeng Tuo
International Journal of Biological Macromolecules.2023; 253: 127048. CrossRef
Migration of rare and abundant species, assembly mechanisms, and ecological networks of microbiomes in drinking water treatment plants: Effects of different treatment processes
Wenjun Sun, Zibo Jing
Journal of Hazardous Materials.2023; 457: 131726. CrossRef
Antimicrobial Activity of Identified Ubiquitin-40S Ribosomal Protein S27a (RPS27A), Ubiquitin-like Protein Fubi, and Ribosomal Protein (S30FAU) in the Starry Flounder (Platichthys stellatus)
Ha-Jeong Son, Gyoungsik Kang, Won-Sik Woo, Kyung-Ho Kim, Min-Young Sohn, Jong-Won Park, Dain Lee, Chan-Il Park
Fishes.2023; 8(4): 187. CrossRef
Microbiological patterns of bacterial infections in tracheostomized children: Reducing uncertainty in continuous care
Miguel García‐Boyano, Francisco José Climent Alcalá, Aroa Rodríguez Alonso, Marta García Fernández de Villalta, Oihane Zubiaur Alonso, Ignacio Rabanal Retolaza, Inmaculada Quiles Melero, Cristina Calvo, Luis Escosa García
Pediatric Pulmonology.2023; 58(12): 3507. CrossRef
Compounds That Have an Anti-Biofilm Effect against Common Bacteria at Very Low Concentrations and Their Antibiotic Combination Effect
Hyeon-Ji Hwang, Dan-dan Li, Jieun Lee, Min Kyung Kang, Hyung Ryong Moon, Joon-Hee Lee
Antibiotics.2023; 12(5): 853. CrossRef
Research Progress of Staphylococcus aureus Biofilm
良薛
Advances in Clinical Medicine.2023; 13(05): 7729. CrossRef
Inhibitory effect of resveratrol on swimming motility and adhesion ability against Salmonella enterica serovar Typhimurium infection
Fei Lou, Kunli Wang, Yunfeng Hou, Xiaolei Shang, Fayin Tang
Microbial Pathogenesis.2023; 184: 106323. CrossRef
An unanticipated discovery of novel naphthalimidopropanediols as potential broad-spectrum antibacterial members
Peng-Li Zhang, Mouna Hind Laiche, Yan-Liang Li, Wei-Wei Gao, Jian-Mei Lin, Cheng-He Zhou
European Journal of Medicinal Chemistry.2022; 241: 114657. CrossRef
Treatment of Pseudomonas aeruginosa infectious biofilms: Challenges and strategies
Rui Yin, Juanli Cheng, Jingyao Wang, Panxin Li, Jinshui Lin
Frontiers in Microbiology.2022;[Epub] CrossRef
In vitro virulence activity of Pseudomonas aeruginosa, enhanced by either Acinetobacter baumannii or Enterococcus faecium through the polymicrobial interactions
Ghazale Laliany, Saeid Amel Jamehdar, Ali Makhdoumi
Archives of Microbiology.2022;[Epub] CrossRef
In vitro visualization and quantitative characterization of Pseudomonas aeruginosa biofilm growth dynamics on polyether ether ketone
Carole S. L. Spake, Ellis M. Berns, Lori Sahakian, Adrian Turcu, Ahsia Clayton, Jillian Glasser, Caitlin Barrett, Douglas Barber, Valentin Antoci, Christopher T. Born, Dioscaris R. Garcia
Journal of Orthopaedic Research.2022; 40(10): 2448. CrossRef
Infecciones en úlceras de pie diabético: diagnóstico, microbiológico y tratamiento
Lucila Gómez, Carlos Tejeda Perez, Cesar Palacio Peñaloza, Angie Tavera Medina, Nayarith Maldonado Ramírez, Alfonso Bettin Martínez, Carlos Beltrán Sanchez
Revista Ciencias Biomédicas.2022; 11(1): 50. CrossRef
Geographic imprint and ecological functions of the abiotic component of periphytic biofilms
Pengfei Sun, Yingyao Liu, Rui Sun, Yonghong Wu, Jan Dolfing
iMeta.2022;[Epub] CrossRef
The Chemical Structure Properties and Promoting Biofilm Activity of Exopolysaccharide Produced by Shigella flexneri
Yinglong Song, Fenglian Ma, Mengying Sun, Guangqing Mu, Yanfeng Tuo
Frontiers in Microbiology.2022;[Epub] CrossRef
Synthesis and Biological Evaluation of 3-(Pyridine-3-yl)-2-Oxazolidinone Derivatives as Antibacterial Agents
Bo Jin, Tong Wang, Jia-yi Chen, Xiao-qing Liu, Yi-xin Zhang, Xiu-ying Zhang, Zun-lai Sheng, Hong-Liang Yang
Frontiers in Chemistry.2022;[Epub] CrossRef
Involvement of the Actinobacillus pleuropneumoniae ompW Gene in Confrontation of Environmental Pressure
Xiabing Chen, Zhiyong Shao, Lijun Wu, Bin He, Wenhai Yang, Jie Chen, Erguang Jin, Qi Huang, Liancheng Lei, Jiajia Xu, Haotian Li, Hui Zhang, Yun Wan, Wu Liu, Rui Zhou
Frontiers in Veterinary Science.2022;[Epub] CrossRef
Potential spoilage of extended shelf-life (ESL) milk by Bacillus subtilis and Bacillus velezensis
James A. Elegbeleye, Elna M. Buys
LWT.2022; 153: 112487. CrossRef
Periphytic biofilms function as a double‐edged sword influencing nitrogen cycling in paddy fields
Pengfei Sun, Yin Chen, Junzhuo Liu, Ying Xu, Lei Zhou, Yonghong Wu
Environmental Microbiology.2022; 24(12): 6279. CrossRef
Anthranilate Acts as a Signal to Modulate Biofilm Formation, Virulence, and Antibiotic Tolerance of Pseudomonas aeruginosa and Surrounding Bacteria
Hyeon-Ji Hwang, Xi-Hui Li, Soo-Kyoung Kim, Joon-Hee Lee, Cezar M. Khursigara
Microbiology Spectrum.2022;[Epub] CrossRef
Coexistence of antibiotic resistance genes, fecal bacteria, and potential pathogens in anthropogenically impacted water
Xiang-Long Zhao, Zhao Qi, Hao Huang, Jian Tu, Xiang-Jun Song, Ke-Zong Qi, Ying Shao
Environmental Science and Pollution Research.2022; 29(31): 46977. CrossRef
Pharmaceutical strategies for the treatment of bacterial biofilms in chronic wounds
Karan Razdan, Jorge Garcia-Lara, V.R. Sinha, Kamalinder K. Singh
Drug Discovery Today.2022; 27(8): 2137. CrossRef
Biofilm Maintenance as an Active Process: Evidence that Biofilms Work Hard to Stay Put
Stefan Katharios-Lanwermeyer, G. A. O’Toole, Michael Y. Galperin
Journal of Bacteriology.2022;[Epub] CrossRef
Prevention and Eradication of Biofilm by Dendrimers: A Possibility Still Little Explored
Silvana Alfei, Debora Caviglia
Pharmaceutics.2022; 14(10): 2016. CrossRef
Periphytic biofilms accumulate manganese, intercepting its emigration from paddy soil
Pengfei Sun, Mengning Gao, Rui Sun, Yonghong Wu, Jan Dolfing
Journal of Hazardous Materials.2021; 411: 125172. CrossRef
Transcriptome Analysis of Pseudomonas aeruginosa Biofilm Following the Exposure to Malaysian Stingless Bee Honey
Nesrin Seder, Mohd Hilmi Abu Bakar, Walid Salem Abu Rayyan
Advances and Applications in Bioinformatics and Chemistry.2021; Volume 14: 1. CrossRef
Antipathogenic Compounds That Are Effective at Very Low Concentrations and Have Both Antibiofilm and Antivirulence Effects against Pseudomonas aeruginosa
Hyeon-Ji Hwang, Heejeong Choi, Sojeong Hong, Hyung Ryong Moon, Joon-Hee Lee, Amanda G. Oglesby
Microbiology Spectrum.2021;[Epub] CrossRef
Agent Based Models of Polymicrobial Biofilms and the Microbiome—A Review
Sherli Koshy-Chenthittayil, Linda Archambault, Dhananjai Senthilkumar, Reinhard Laubenbacher, Pedro Mendes, Anna Dongari-Bagtzoglou
Microorganisms.2021; 9(2): 417. CrossRef
Microbial biofilm ecology, in silico study of quorum sensing receptor-ligand interactions and biofilm mediated bioremediation
Biji Balan, Amit S. Dhaulaniya, Diksha A. Varma, Kushneet K. Sodhi, Mohit Kumar, Manisha Tiwari, Dileep Kumar Singh
Archives of Microbiology.2021; 203(1): 13. CrossRef
Characterization of Binary Biofilms of Listeria monocytogenes and Lactobacillus and Their Response to Chlorine Treatment
Magdalena A. Olszewska, Francisco Diez-Gonzalez
Frontiers in Microbiology.2021;[Epub] CrossRef
Relevance of Biofilm Models in Periodontal Research: From Static to Dynamic Systems
María Carmen Sánchez, Andrea Alonso-Español, Honorato Ribeiro-Vidal, Bettina Alonso, David Herrera, Mariano Sanz
Microorganisms.2021; 9(2): 428. CrossRef
Comparison of techniques for counting prokaryotes in marine planktonic and biofilm samples
Vanessa Ochi Agostini, Letícia Terres Rodrigues, Alexandre José Macedo, Erik Muxagata
Scientia Marina.2021; 85(3): 211. CrossRef
Real-time monitoring ofPseudomonas aeruginosabiofilm growth dynamics and persister cells’ eradication
Miglė Žiemytė, Miguel Carda-Diéguez, Juan C. Rodríguez-Díaz, Maria P. Ventero, Alex Mira, María D. Ferrer
Emerging Microbes & Infections.2021; 10(1): 2062. CrossRef
The serine protease HtrA plays a key role in heat-induced dispersal of pneumococcal biofilms
Yashuan Chao, Caroline Bergenfelz, Renhua Sun, Xiao Han, Adnane Achour, Anders P. Hakansson
Scientific Reports.2020;[Epub] CrossRef
Further understanding of Pseudomonas aeruginosa’s ability to horizontally acquire virulence: possible intervention strategies
James Redfern, Mark C. Enright
Expert Review of Anti-infective Therapy.2020; 18(6): 539. CrossRef
Coordinated regulation of anthranilate metabolism and bacterial virulence by the GntR family regulator MpaR in Pseudomonas aeruginosa
Tietao Wang, Yihang Qi, Zhihan Wang, Jingru Zhao, Linxuan Ji, Jun Li, Zhao Cai, Liang Yang, Min Wu, Haihua Liang
Molecular Microbiology.2020; 114(5): 857. CrossRef
Biofilm and Quorum sensing mediated pathogenicity in Pseudomonas aeruginosa
Kathirvel Brindhadevi, Felix LewisOscar, Eleftherios Mylonakis, Sabarathinam Shanmugam, Tikendra Nath Verma, Arivalagan Pugazhendhi
Process Biochemistry.2020; 96: 49. CrossRef
Thermoregulation of Pseudomonas aeruginosa Biofilm Formation
Suran Kim, Xi-Hui Li, Hyeon-Ji Hwang, Joon-Hee Lee, Danilo Ercolini
Applied and Environmental Microbiology.2020;[Epub] CrossRef
Inhibitors of Antibiotic Resistance Mechanisms: Clinical Applications and Future Perspectives
Barbara Parrino, Daniela Carbone, Girolamo Cirrincione, Patrizia Diana, Stella Cascioferro
Future Medicinal Chemistry.2020; 12(5): 357. CrossRef
Microbial Biosurfactants in Cosmetic and Personal Skincare Pharmaceutical Formulations
Simms A. Adu, Patrick J. Naughton, Roger Marchant, Ibrahim M. Banat
Pharmaceutics.2020; 12(11): 1099. CrossRef
Novel eradication methods for Staphylococcus aureus biofilm in poultry farms and abattoirs using disinfectants loaded onto silver and copper nanoparticles
Mona M. Elsayed, Fatma A. Elgohary, Amira I. Zakaria, Rasha M. Elkenany, Ayman Y. EL-Khateeb
Environmental Science and Pollution Research.2020; 27(24): 30716. CrossRef
Oxidative stress under low oxygen conditions triggers hyperflagellation and motility in the Antarctic bacterium Pseudomonas extremaustralis
Esmeralda C. Solar Venero, Martiniano M. Ricardi, María Gomez-Lozano, Søren Molin, Paula M. Tribelli, Nancy I. López
Extremophiles.2019; 23(5): 587. CrossRef
Synthesis and characterization of chitosan oligosaccharide-capped gold nanoparticles as an effective antibiofilm drug against the Pseudomonas aeruginosa PAO1
Fazlurrahman Khan, Jang-Won Lee, Panchanathan Manivasagan, Dung Thuy Nguyen Pham, Junghwan Oh, Young-Mog Kim
Microbial Pathogenesis.2019; 135: 103623. CrossRef
Physico-chemical characterization of caesium and strontium using fluorescent intensity of bacteria in a microfluidic platform
Changhyun Roh, Thi Toan Nguyen, Jae-Jin Shim, Chankyu Kang
Royal Society Open Science.2019; 6(5): 182069. CrossRef
Perspectives towards antibiotic resistance: from molecules to population
Joon-Hee Lee
Journal of Microbiology.2019; 57(3): 181. CrossRef
Theaflavin-3,3′-Digallate Suppresses Biofilm Formation, Acid Production, and Acid Tolerance in Streptococcus mutans by Targeting Virulence Factors
Sa Wang, Yuan Wang, Ying Wang, Zhuhui Duan, Zongxin Ling, Wenzhi Wu, Suman Tong, Huiming Wang, Shuli Deng
Frontiers in Microbiology.2019;[Epub] CrossRef
Rhamnolipid-involved antibiotics combinations improve the eradication of Helicobacter pylori biofilm in vitro: A comparison with conventional triple therapy
Xiaonan Chen, Pengyu Li, Yuanna Shen, Yiqing Zou, Gang Yuan, Haiyan Hu
Microbial Pathogenesis.2019; 131: 112. CrossRef
Biofilm Disruption Utilizing α/β Chimeric Polypeptide Molecular Brushes
Si Zhang, Xi-Mian Xiao, Fan Qi, Peng-Cheng Ma, Wei-Wei Zhang, Cheng-Zhi Dai, Dan-Feng Zhang, Run-Hui Liu
Chinese Journal of Polymer Science.2019; 37(11): 1105. CrossRef
Circular pellicles formed by Pseudomonas alkylphenolica KL28 are a sophisticated architecture principally designed by matrix substance
Myeong Mi Song, Yaligara Veeranagouda, Munkhtsatsral Ganzorig, Kyoung Lee
Journal of Microbiology.2018; 56(11): 790. CrossRef
Recent perspectives on the molecular basis of biofilm formation by Pseudomonas aeruginosa and approaches for treatment and biofilm dispersal
Sinosh Skariyachan, Vaishnavi Sneha Sridhar, Swathi Packirisamy, Supreetha Toplar Kumargowda, Sneha Basavaraj Challapilli
Folia Microbiologica.2018; 63(4): 413. CrossRef
Pseudomonas aeruginosaBiofilms: Host Response and Clinical Implications in Lung Infections
Nicholas M. Maurice, Brahmchetna Bedi, Ruxana T. Sadikot
American Journal of Respiratory Cell and Molecular Biology.2018; 58(4): 428. CrossRef
Antibiofilm effect of biofilm-dispersing agents on clinical isolates of Pseudomonas aeruginosa with various biofilm structures
Soo-Kyoung Kim, Xi-Hui Li, Hyeon-Ji Hwang, Joon-Hee Lee
Journal of Microbiology.2018; 56(12): 902. CrossRef
Molecules and Mechanisms Underlying the Antimicrobial Activity of Escapin, anl-Amino Acid Oxidase from the Ink of Sea Hares
Charles D. Derby, Eric S. Gilbert, Phang C. Tai
The Biological Bulletin.2018; 235(1): 52. CrossRef
PAMDB: a comprehensive Pseudomonas aeruginosa metabolome database
Weiliang Huang, Luke K Brewer, Jace W Jones, Angela T Nguyen, Ana Marcu, David S Wishart, Amanda G Oglesby-Sherrouse, Maureen A Kane, Angela Wilks
Nucleic Acids Research.2018; 46(D1): D575. CrossRef
Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa
Donghoon Kang, Natalia V. Kirienko
Journal of Microbiology.2018; 56(7): 449. CrossRef
Sensitizing bacterial cells to antibiotics by shape recovery triggered biofilm dispersion
Sang Won Lee, Huan Gu, James Bryan Kilberg, Dacheng Ren
Acta Biomaterialia.2018; 81: 93. CrossRef
Controlling of microbial biofilms formation: Anti- and probiofilm agents
V. K. Plakunov, S. V. Mart’yanov, N. A. Teteneva, M. V. Zhurina
Microbiology.2017; 86(4): 423. CrossRef
Effect of bacterial components of mixed culture supernatants of planktonic and biofilm Pseudomonas aeruginosa with commensal Escherichia coli on the neutrophil response in vitro
Irina L Maslennikova, Marina V Kuznetsova, Irina V Nekrasova, Sergei V Shirshev
Pathogens and Disease.2017;[Epub] CrossRef
Mutation of the cyclic di-GMP phosphodiesterase gene in Burkholderia lata SK875 attenuates virulence and enhances biofilm formation
Hae-In Jung, Yun-Jung Kim, Yun-Jung Lee, Hee-Soo Lee, Jung-Kee Lee, Soo-Ki Kim
Journal of Microbiology.2017; 55(10): 800. CrossRef
Relative susceptibility of airway organisms to antimicrobial effects of nitric oxide
Alan D. Workman, Ryan M. Carey, Michael A. Kohanski, David W. Kennedy, James N. Palmer, Nithin D. Adappa, Noam A. Cohen
International Forum of Allergy & Rhinology.2017; 7(8): 770. CrossRef
Mechanisms and Regulation of Extracellular DNA Release and Its Biological Roles in Microbial Communities
Alejandra L. Ibáñez de Aldecoa, Olga Zafra, José E. González-Pastor
Frontiers in Microbiology.2017;[Epub] CrossRef
Biofilm dispersal: multiple elaborate strategies for dissemination of bacteria with unique properties
Cyril Guilhen, Christiane Forestier, Damien Balestrino
Molecular Microbiology.2017; 105(2): 188. CrossRef
Phage “delay” towards enhancing bacterial escape from biofilms: a more comprehensive way of viewing resistance to bacteriophages
Stephen T. Abedon
AIMS Microbiology.2017; 3(2): 186. CrossRef
Antibiofilm agents: A new perspective for antimicrobial strategy
Xi-Hui Li, Joon-Hee Lee
Journal of Microbiology.2017; 55(10): 753. CrossRef
The Social Life of Aeromonas through Biofilm and Quorum Sensing Systems
Emilie Talagrand-Reboul, Estelle Jumas-Bilak, Brigitte Lamy
Frontiers in Microbiology.2017;[Epub] CrossRef
Synthetic biology engineering of biofilms as nanomaterials factories
Peter Q. Nguyen
Biochemical Society Transactions.2017; 45(3): 585. CrossRef
Anti-biofilm effects of anthranilate on a broad range of bacteria
Xi-Hui Li, Soo-Kyoung Kim, Joon-Hee Lee
Scientific Reports.2017;[Epub] CrossRef
Rhamnolipids Mediate an Interspecies Biofilm Dispersal Signaling Pathway
Arunima Bhattacharjee, Tyler D. Nusca, Allon I. Hochbaum
ACS Chemical Biology.2016; 11(11): 3068. CrossRef
Human upper airway epithelium produces nitric oxide in response to Staphylococcus epidermidis
Ryan M. Carey, Bei Chen, Nithin D. Adappa, James N. Palmer, David W. Kennedy, Robert J. Lee, Noam A. Cohen
International Forum of Allergy & Rhinology.2016; 6(12): 1238. CrossRef
N‐acetylcysteine eradicates Pseudomonas aeruginosa biofilms in bone cement
Mehmet Emin Onger, Hasan Gocer, Dilek Emir, Suleyman Kaplan
Scanning.2016; 38(6): 766. CrossRef
Plasticity of Candida albicans Biofilms
David R. Soll, Karla J. Daniels
Microbiology and Molecular Biology Reviews.2016; 80(3): 565. CrossRef

Editorial

EDITORIAL] Perspectives towards antibiotic resistance: from molecules to population: Joon-Hee Lee; J. Microbiol. 2019;57(3):181-184.; DOI: https://doi.org/10.1007/s12275-019-0718-8

58 View
0 Download
27 Web of Science
29 Crossref

Abstract

For a long time, antibiotics have been ‘magical weapons’ to combat pathogenic microbes. The success of antibiotics is now greatly threatened by resistance to antibiotics and many scientists have already talked about the coming of the postantibiotic era. This special issue is prepared to understand recent research findings and new concepts about antibiotic resistance. Above all, this special issue explores mechanisms for the generation, selection, and spread of antibiotic resistance, and gives insight into what to target to prevent the development of antibiotic resistance. Just as antibiotics came from the concept of “magic bullet”, a breakthrough will come from a new concept based on a profound understanding of antibiotic resistance.

Citations

Citations to this article as recorded by

Photosensitizer associated with efflux pump inhibitors as a strategy for photodynamic therapy against bacterial resistance
Ieda Vieira da Cunha, Douglas Davison da Silva Oliveira, Gabriel Guimarães Calefi, Nagela Bernadelli Sousa Silva, Carlos Henrique Gomes Martins, Celso de Oliveira Rezende Júnior, Tayana Mazin Tsubone
European Journal of Medicinal Chemistry.2025; 284: 117197. CrossRef
Escherichia coli: Research Progress on Drug Resistance Mechanisms and Emerging Treatment Strategies
利君秦
Advances in Clinical Medicine.2025; 15(03): 240. CrossRef
Mode of Action of Biogenic Silver, Zinc, Copper, Titanium and Cobalt Nanoparticles Against Antibiotics Resistant Pathogens
Muhammad Summer, Shaukat Ali, Hafiz Muhammad Tahir, Rimsha Abaidullah, Umaima Fiaz, Shumaila Mumtaz, Hashim Fiaz, Ali Hassan, Tafail Akbar Mughal, Muhammad Adeel Farooq
Journal of Inorganic and Organometallic Polymers and Materials.2024; 34(4): 1417. CrossRef
When the solution becomes the problem: a review on antimicrobial resistance in dairy cattle
Ana José Pires, Gonçalo Pereira, David Fangueiro, Ricardo Bexiga, Manuela Oliveira
Future Microbiology.2024; 19(10): 903. CrossRef
Mechanism of antibacterial resistance, strategies and next-generation antimicrobials to contain antimicrobial resistance: a review
Wubetu Yihunie Belay, Melese Getachew, Bantayehu Addis Tegegne, Zigale Hibstu Teffera, Abebe Dagne, Tirsit Ketsela Zeleke, Rahel Belete Abebe, Abebaw Abie Gedif, Abebe Fenta, Getasew Yirdaw, Adane Tilahun, Yibeltal Aschale
Frontiers in Pharmacology.2024;[Epub] CrossRef
How Restrictive Legislation Influences Antimicrobial Susceptibility in Selected Bacterial Isolates from the Canine Vagina
Anna Sophia Leps, Babette Klein, Marianne Schneider, Sandra Goericke-Pesch
Antibiotics.2024; 13(10): 946. CrossRef
Escherichia coli resistance mechanism AcrAB-TolC efflux pump interactions with commonly used antibiotics: a molecular dynamics study
Brooke L. Smith, Sandun Fernando, Maria D. King
Scientific Reports.2024;[Epub] CrossRef
Enhancing antimicrobial resistance detection with MetaGeneMiner: Targeted gene extraction from metagenomes
Chang Liu, Zizhen Tang, Linzhu Li, Yan Kang, Yue Teng, Yan Yu
Chinese Medical Journal.2024; 137(17): 2092. CrossRef
Escherichia coli as a sentinel in the assessment of antimicrobial resistance in the tilapia production chain: from production environment to the final product
Sthéfany Da Cunha Dias, Letícia Roberta Martins Costa, Ana Beatriz Garcez Buiatte, Marcus Vinícius Coutinho Cossi, Luís Augusto Nero, Ricardo Seiti Yamatogi, Luciano dos Santos Bersot, Juliano Gonçalves Pereira
Frontiers in Antibiotics.2024;[Epub] CrossRef
Challenges and Emerging Molecular Approaches in Combating Antimicrobial Resistance
Gene Philip Levee Ynion, Christian Jay Rosal, Arvin Zulueta, Angelo Ordanel, Christopher Marlowe Caipang
Journal of Bacteriology and Virology.2024; 54(1): 12. CrossRef
Efficacy of a Novel Antibacterial Agent Exeporfinium Chloride, (XF-73), Against Antibiotic-Resistant Bacteria in Mouse Superficial Skin Infection Models
Chenrui Zhang, Jinping Li, Rong Lu, Song Wang, Zheng Fu, Zhi Yao
Infection and Drug Resistance.2023; Volume 16: 4867. CrossRef
Antimicrobial Resistance: A Growing Serious Threat for Global Public Health
Md. Abdus Salam, Md. Yusuf Al-Amin, Moushumi Tabassoom Salam, Jogendra Singh Pawar, Naseem Akhter, Ali A. Rabaan, Mohammed A. A. Alqumber
Healthcare.2023; 11(13): 1946. CrossRef
Eco-friendly fabricated multibioactive Ca(II)-antibiotic coordination framework coating on zinc towards improved bone tissue regeneration
Juliana Mota, Catarina Bravo, Catarina Santos, Paula C. Alves, Patrícia Rijo, Alexandra M. Antunes, Liliana Grenho, M. Helena Fernandes, Marta M. Alves, Vânia André
Colloids and Surfaces B: Biointerfaces.2023; 221: 113008. CrossRef
Characteristics and Ecological Risk Analysis of Antibiotic Pollution in Typical Lake
雨波刘
Advances in Environmental Protection.2023; 13(01): 88. CrossRef
Epigenetic-Based Regulation of Transcriptome in Escherichia coli Adaptive Antibiotic Resistance
Patrizia D’Aquila, Francesco De Rango, Ersilia Paparazzo, Giuseppe Passarino, Dina Bellizzi, Christine Josenhans
Microbiology Spectrum.2023;[Epub] CrossRef
Compounds That Have an Anti-Biofilm Effect against Common Bacteria at Very Low Concentrations and Their Antibiotic Combination Effect
Hyeon-Ji Hwang, Dan-dan Li, Jieun Lee, Min Kyung Kang, Hyung Ryong Moon, Joon-Hee Lee
Antibiotics.2023; 12(5): 853. CrossRef
Antibiotic resistance of Escherichia coli isolates obtained from burn patients
Iman ALSARHAN, Sedat ÇAM
Gümüşhane Üniversitesi Fen Bilimleri Enstitüsü Dergisi.2023;[Epub] CrossRef
Molecular cloning and functional research in drug-resistance of transposase gene in Burkholderia pseudomallei
Xiu Hao, Hou Jie, Quan Yunfan, Fu Tingting, Dong Sufang, Chen Chuizhe, Sun Qinhui
African Journal of Microbiology Research.2023; 17(3): 68. CrossRef
Antimicrobial Susceptibility of Bacteria Isolated from Freshwater Mussels in the Wildcat Creek Watershed, Indiana, United States
John E. Ekakoro, Lynn F. Guptill, G. Kenitra Hendrix, Lauren Dorsey, Audrey Ruple
Antibiotics.2023; 12(4): 728. CrossRef
The Assessment of Antimicrobial and Anti-Biofilm Activity of Essential Oils against Staphylococcus aureus Strains
Caglar Ersanli, Athina Tzora, Ioannis Skoufos, Konstantina Fotou, Eleni Maloupa, Katerina Grigoriadou, Chrysoula (Chrysa) Voidarou, Dimitrios I. Zeugolis
Antibiotics.2023; 12(2): 384. CrossRef
Quercetin: Synergistic Interaction with Antibiotics against Colistin-Resistant Acinetobacter baumannii
Elif Odabaş Köse, Özlem Koyuncu Özyurt, Süreyya Bilmen, Hakan Er, Cansu Kilit, Esra Aydemir
Antibiotics.2023; 12(4): 739. CrossRef
An Outer Membrane Protein YiaD Contributes to Adaptive Resistance of Meropenem in Acinetobacter baumannii
Lei Han, Yiyuan Gao, Yuqing Liu, Siyu Yao, Shuyan Zhong, Sirui Zhang, Jingdan Wang, Peng Mi, Yurong Wen, Zhenlin Ouyang, Jing Zhang, Mona Mohamed Al-Shamiri, Pu Li, Shaoshan Han, Amanda G. Oglesby
Microbiology Spectrum.2022;[Epub] CrossRef
Knowledge, Attitudes and Practices Related to Medication, Antibiotics, and Vaccination among Public Service Population: National Survey Conducted in France
Virginie-Eve Lvovschi, Florence Carrouel, Benjamin du Sartz de Vigneulles, Michel Lamure, Geneviève Motyka, Laurie Fraticelli, Claude Dussart
International Journal of Environmental Research and Public Health.2022; 19(21): 14044. CrossRef
Multiplex SERS-based lateral flow assay for one-step simultaneous detection of neomycin and lincomycin in milk
Qiaoqiao Shi, Chunxu Tao, Dezhao Kong
European Food Research and Technology.2022; 248(8): 2157. CrossRef
A new antibacterial nano-system based on hematoporphyrin-carboxymethyl chitosan conjugate for enhanced photostability and photodynamic activity
Ting Zhou, Yihua Yin, Weiquan Cai, Haibo Wang, Lihong Fan, Guanghua He, Jingli Zhang, Mengqing Jiang, Jinsheng Liu
Carbohydrate Polymers.2021; 269: 118242. CrossRef
A novel smaller β‐defensin‐derived peptide is active against multidrug‐resistant bacterial strains
Roberta Colicchio, Ersilia Nigro, Irene Colavita, Chiara Pagliuca, Salvatore Di Maro, Stefano Tomassi, Elena Scaglione, Fortunata Carbone, Maria Vincenza Carriero, Giuseppe Matarese, Aurora Daniele, Sandro Cosconati, Antonello Pessi, Francesco Salvatore,
The FASEB Journal.2021;[Epub] CrossRef
Rediscovery of antimicrobial peptides as therapeutic agents
Minkyung Ryu, Jaeyeong Park, Ji-Hyun Yeom, Minju Joo, Kangseok Lee
Journal of Microbiology.2021; 59(2): 113. CrossRef
Leveraging metal oxide nanoparticles for bacteria tracing and eradicating
En Ren, Chang Zhang, Dengfeng Li, Xin Pang, Gang Liu
VIEW.2020;[Epub] CrossRef
Antimicrobial Resistance in Bacteria: Mechanisms, Evolution, and Persistence
Eirini Christaki, Markella Marcou, Andreas Tofarides
Journal of Molecular Evolution.2020; 88(1): 26. CrossRef

Regulation of the sufABCDSE Operon by Fur: Joon-Hee Lee , Won-Sik Yeo , Jung-Hye Roe; J. Microbiol. 2003;41(2):109-114.

40 View
0 Download

Abstract: A promoter that is inducible by paraquat and menadione, the superoxide generators, independently of soxRS has been found in front of the sufABCDSE operon in Escherichia coli. Based on the observation that SufA is a holomog of IscA that functions in the assembly of iron sulfur cluster and the sufA promoter (sufAp) contains a putative Fur-binding consensus, we investigated whether this gene is regulated by Fur, a ferric uptake regulator. When examined in several sufAp-lacZ chromosomal fusion strains, sufAp was induced by EDTA, an iron chelator and a well-known Fur-inducer. The basal level of sufA expression increased dramatically in fur mutant, suggesting repression of sufAp by Fur. The derepression in fur mutant and EDTA-induction of sufA expression required nucleotides up to -61, where a putative Fur box is located. Purified Fur protein bound to the DNA fragment containing the putative Fur box between -35 and -10 promoter elements. The regulation by Fur and menadione induction of sufAp acted independently. The rpoS mutation increased sufA induction by menadione, suggesting that the stationary sigma factor RpoS acts negatively on sufA induction.

First
Prev
Page of 1
Next
Last

Search