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MINIREVIEW]Phytochemicals for the treatment of COVID-19
Erica Españo , Jiyeon Kim , Kiho Lee , Jeong-Ki Kim
J. Microbiol. 2021;59(11):959-977.   Published online November 1, 2021
DOI: https://doi.org/10.1007/s12275-021-1467-z
  • 49 View
  • 0 Download
  • 18 Web of Science
  • 18 Crossref
AbstractAbstract
The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle.

Citations

Citations to this article as recorded by  
  • Role of dietary supplements in the continuous battle against COVID‐19
    Rahela Zaman, Vignesh Ravichandran, Chung Keat Tan
    Phytotherapy Research.2024; 38(2): 1071.     CrossRef
  • The Potential of Anti-coronavirus Plant Secondary Metabolites in COVID-19 Drug Discovery as an Alternative to Repurposed Drugs: A Review
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  • In Silico Screening of Some Active Phytochemicals to Identify Promising Inhibitors Against SARS-CoV-2 Targets
    V. Alagarsamy, V. Raja Solomon, S. Murugesan, P. Shyam Sundar, MD. Muzaffar-Ur-Rehman, A. Chandu, A. Dharshini Aishwarya, B. Narendhar, M.T. Sulthana, V. Ravikumar
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    Natural Resources for Human Health.2023; 4(1): 51.     CrossRef
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    Inflammopharmacology.2023; 31(2): 573.     CrossRef
  • Curcumin-Based Nanomedicines in the Treatment of Inflammatory and Immunomodulated Diseases: An Evidence-Based Comprehensive Review
    Lucas Fornari Laurindo, Gabriel Magno de Carvalho, Bárbara de Oliveira Zanuso, Maria Eduardo Figueira, Rosa Direito, Ricardo de Alvares Goulart, Daiene Santos Buglio, Sandra Maria Barbalho
    Pharmaceutics.2023; 15(1): 229.     CrossRef
  • Changes in phytochemical compositions and antioxidant activity of Schisandra sphenathera fruit during ripening
    Bohan Ma, Xinghua Zhao, Bin Dai, Mengge Zhao, Xingbin Yang, Langjun Cui, Hongjun Shao
    Industrial Crops and Products.2023; 199: 116773.     CrossRef
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    Luxita Sharma, Dhananjay Sharma
    Nutrition & Food Science.2023; 53(4): 659.     CrossRef
  • Current Update of Phytotherapeutic Agents in the Treatment of COVID-19: In-Silico Based Virtual Screening Approach for the Development of Antiviral Drug
    Veena Ramesh, Seema A. Kulkarni, Palaniyandi Velusamy, Velmurugan Devadasan, Panneer Devaraju, Kandathil Narayanan Rajnish, Thirumurthy Madhavan, Periasamy Anbu, Palaniappan Ramasamy, Rajamanikandan Sundarraj
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  • Effective food hygiene principles and dietary intakes to reinforce the immune system for prevention of COVID-19: a systematic review
    Jalaledin Mirzay-Razaz, Majid Hassanghomi, Marjan Ajami, Glareh Koochakpoor, Firoozeh Hosseini-Esfahani, Parvin Mirmiran
    BMC Nutrition.2022;[Epub]     CrossRef
  • Beneficial effect of polyphenols in COVID‐19 and the ectopic F1FO‐ATP synthase: Is there a link?
    Isabella Panfoli, Alfonso Esposito
    Journal of Cellular Biochemistry.2022; 123(8): 1281.     CrossRef
  • In vitro inhibition of SARS-CoV-2 Infection by dry algae powders
    Daniel Garcia-Ruiz, Erendira Villalobos-Sánchez, David Alam-Escamilla, Darwin Elizondo-Quiroga
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  • Schizophyllum commune Reduces Expression of the SARS-CoV-2 Receptors ACE2 and TMPRSS2
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    Shiv Kumar Prajapati, Akanksha Malaiya, Gaurav Mishra, Dolly Jain, Payal Kesharwani, Nishi Mody, Amirhossein Ahmadi, Rishi Paliwal, Ankit Jain
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  • Computational screening for investigating the synergistic regulatory potential of drugs and phytochemicals in combination with 2-deoxy-D-glucose against SARS-CoV-2
    Anshika Gupta, Shweta Singh Chauhan, Anamika Singh Gaur, Ramakrishnan Parthasarathi
    Structural Chemistry.2022; 33(6): 2179.     CrossRef
  • BOTANICALS AS PROSPECTIVE AGENTS AGAINST SARS-COV-2 VIRUS
    V. DUSHENKOV, A. DUSHENKOV
    AVICENNA BULLETIN.2022; 24(1): 113.     CrossRef
Journal Article
Optimization of bacterial sporulation using economic nutrient for self-healing concrete
Youngung Ryu , Ki-Eun Lee , In-Tae Cha , Woojun Park
J. Microbiol. 2020;58(4):288-296.   Published online February 27, 2020
DOI: https://doi.org/10.1007/s12275-020-9580-y
  • 48 View
  • 0 Download
  • 17 Web of Science
  • 19 Crossref
AbstractAbstract
The use of heat- and alkali-resistant bacteria is essential for the biological repair of damaged concrete. Lysinibacillus boronitolerans YS11 was isolated from the rhizosphere of Miscanthus sacchariflorus. The increased pH in the urea-minus condition during the growth of the YS11 strain promoted calcium carbonate (CaCO3) formation. To identify the optimum medium that promoted the growth of the YS11 strain, a Plackett- Burman design was conducted for the screening process. Consequently, malt powder, rice bran, (NH4)2SO4, and corn syrup were chosen to enhance YS11 growth. The optimization of these four useful factors was carried out using a central composite design. To obtain higher survivability in mortar, the sporulation process is essential, and additional factors such as Mn2+, Fe2+, and Ca2+ were found to contribute to sporulation. A mixture of L. boronitolerans YS11 spore powder, cement, paste, sand, yeast extract, calcium lactate, and water showed a healing effect on a 0.3 mm mortar crack in 7 days. Furthermore, calcium carbonate precipitation was observed over the crack surface. Thus, we confirmed that mortar treated with YS11 spore powder was effective in healing micro-cracks in concrete.

Citations

Citations to this article as recorded by  
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