Journal of Microbiology

Review

[MINIREVIEW]Gain and loss of antibiotic resistant genes in multidrug resistant bacteria: One Health perspective: Misung Kim , Jaeeun Park , Mingyeong Kang , Jihye Yang , Woojun Park; J. Microbiol. 2021;59(6):535-545. Published online April 20, 2021; DOI: https://doi.org/10.1007/s12275-021-1085-9

50 View
0 Download
32 Web of Science
31 Crossref

The emergence of multidrug resistance (MDR) has become a global health threat due to the increasing unnecessary use of antibiotics. Multidrug resistant bacteria occur mainly by accumulating resistance genes on mobile genetic elements (MGEs), made possible by horizontal gene transfer (HGT). Humans and animal guts along with natural and engineered environments such as wastewater treatment plants and manured soils have proven to be the major reservoirs and hotspots of spreading antibiotic resistance genes (ARGs). As those environments support the dissemination of MGEs through the complex interactions that take place at the human-animalenvironment interfaces, a growing One Health challenge is for multiple sectors to communicate and work together to prevent the emergence and spread of MDR bacteria. However, maintenance of ARGs in a bacterial chromosome and/or plasmids in the environments might place energy burdens on bacterial fitness in the absence of antibiotics, and those unnecessary ARGs could eventually be lost. This review highlights and summarizes the current investigations into the gain and loss of ARG genes in MDR bacteria among human-animal- environment interfaces. We also suggest alternative treatments such as combinatory therapies or sequential use of different classes of antibiotics/adjuvants, treatment with enzymeinhibitors, and phage therapy with antibiotics to solve the MDR problem from the perspective of One Health issues.

Citations

Citations to this article as recorded by

Removing high strength lincomycin in pharmaceutical wastewater by a bacteria microalgae consortium co-immobilized filter
Yonghong Li, Lifei Feng, Guanghua Li, Jian Wang, Keke Li
Bioresource Technology.2025; 415: 131704. CrossRef
Investigation of the antimicrobial susceptibility patterns of marine cyanobacteria in Bohai Bay: Cyanobacteria may be important hosts of antibiotic resistance genes in marine environment
Rui Xin, Ying Zhang, Kai Zhang, Yichen Yang, Yongzheng Ma, Zhiguang Niu
Science of The Total Environment.2024; 909: 168516. CrossRef
Hospital and municipal wastewater as a source of carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa in the environment: a review
Magdalena Męcik, Kornelia Stefaniak, Monika Harnisz, Ewa Korzeniewska
Environmental Science and Pollution Research.2024; 31(36): 48813. CrossRef
Unexpected vulnerability of Enterococcus faecium to polymyxin B under anaerobic condition
Yongjun Son, Bitnara Kim, Pureun Kim, Jihyeon Min, Yerim Park, Jihye Yang, Wonjae Kim, Masanori Toyofuku, Woojun Park
Gut Microbes.2024;[Epub] CrossRef
Antimicrobial Resistance in the Context of Animal Production and Meat Products in Poland—A Critical Review and Future Perspective
Patryk Wiśniewski, Miłosz Trymers, Wioleta Chajęcka-Wierzchowska, Katarzyna Tkacz, Anna Zadernowska, Monika Modzelewska-Kapituła
Pathogens.2024; 13(12): 1123. CrossRef
Resistome Diversity in Escherichia coli Isolates of Global Wastewaters
Pavithra Anantharaman Sudhakari, Bhaskar Chandra Mohan Ramisetty
Microbial Drug Resistance.2024; 30(1): 37. CrossRef
Transfer dynamics of antimicrobial resistance among gram-negative bacteria
Bangjuan Wang, Muhammad Haris Raza Farhan, Linlin Yuan, Yuxin Sui, Jinhua Chu, Xiaohan Yang, Yuxin Li, Lingli Huang, Guyue Cheng
Science of The Total Environment.2024; 954: 176347. CrossRef
Pedobacter faecalis sp. nov., isolated from the faeces of eland, Taurotragus oryx
Yerim Park, Jihyeon Min, Bitnara Kim, Woojun Park
International Journal of Systematic and Evolutionary Microbiology .2024;[Epub] CrossRef
Co-selection mechanism for bacterial resistance to major chemical pollutants in the environment
Meixia Huo, Xiangyue Xu, Kun Mi, Wenjin Ma, Qin Zhou, Xudong Lin, Guyue Cheng, Lingli Huang
Science of The Total Environment.2024; 912: 169223. CrossRef
Repeated Exposure of Vancomycin to Vancomycin-Susceptible Staphylococcus aureus (VSSA) Parent Emerged VISA and VRSA Strains with Enhanced Virulence Potentials
An Nguyen, J. Jean Sophy Roy, Ji-Hoon Kim, Kyung-Hee Yun, Wonsik Lee, Kyeong Kyu Kim, Truc Kim, Akhilesh Kumar Chaurasia
Journal of Microbiology.2024; 62(7): 535. CrossRef
Human Disturbance Increases Health Risks to Golden Snub-Nosed Monkeys and the Transfer Risk of Pathogenic Antibiotic-Resistant Bacteria from Golden Snub-Nosed Monkeys to Humans
Shuzhen Zou, Tingting Yuan, Tan Lu, Jiayu Yan, Di Kang, Dayong Li
Animals.2023; 13(19): 3083. CrossRef
Longitudinal study of the short- and long-term effects of hospitalisation and oral trimethoprim-sulfadiazine administration on the equine faecal microbiome and resistome
Mathijs J. P. Theelen, Roosmarijn E. C. Luiken, Jaap A. Wagenaar, Marianne M. Sloet van Oldruitenborgh-Oosterbaan, John W. A. Rossen, Femke J. W. C. Schaafstra, David A. van Doorn, Aldert L. Zomer
Microbiome.2023;[Epub] CrossRef
Genomic evidences of gulls as reservoirs of critical priority CTX-M-producing Escherichia coli in Corcovado Gulf, Patagonia
Danny Fuentes-Castillo, Daniela Castro-Tardón, Fernanda Esposito, Ingrith Neves, Larissa Rodrigues, Herrison Fontana, Bruna Fuga, José L. Catão-Dias, Nilton Lincopan
Science of The Total Environment.2023; 874: 162564. CrossRef
Poultry manure-derived microorganisms as a reservoir and source of antibiotic resistance genes transferred to soil autochthonous microorganisms
Magdalena Męcik, Martyna Buta-Hubeny, Łukasz Paukszto, Mateusz Maździarz, Izabela Wolak, Monika Harnisz, Ewa Korzeniewska
Journal of Environmental Management.2023; 348: 119303. CrossRef
Fabrication of Co-Assembly from Berberine and Tannic Acid for Multidrug-Resistant Bacteria Infection Treatment
Tingting Zheng, Huan Chen, Chenyang Wu, Jinrui Wang, Mengyao Cui, Hanyi Ye, Yifan Feng, Ying Li, Zhengqi Dong
Pharmaceutics.2023; 15(7): 1782. CrossRef
Grazing disturbance increased the mobility, pathogenicity and host microbial species of antibiotic resistance genes, and multidrug resistance genes posed the highest risk in the habitats of wild animals
Shuzhen Zou, Tan Lu, Cailiang Huang, Jie Wang, Dayong Li
Frontiers in Environmental Science.2023;[Epub] CrossRef
Application of electrochemical oxidation for the enhancement of antibiotic resistant bacteria removal in stormwater bioretention cells
XiaoJun Zuo, SongHu Zhang, FanXin Kong, QiangQiang Xu
Science of The Total Environment.2023; 861: 160477. CrossRef
Blue Light Sensing BlsA-Mediated Modulation of Meropenem Resistance and Biofilm Formation in Acinetobacter baumannii
Jihye Yang, Sohyeon Yun, Woojun Park, Mark J. Mandel
mSystems.2023;[Epub] CrossRef
AamA-mediated epigenetic control of genome-wide gene expression and phenotypic traits in Acinetobacter baumannii ATCC 17978
Jihye Yang, Yongjun Son, Mingyeong Kang, Woojun Park
Microbial Genomics .2023;[Epub] CrossRef
Response behavior of antibiotic resistance genes and human pathogens to slope gradient and position: An environmental risk analysis in sloping cultivated land
Kailin Xu, Xuna Liu, Lina Pang, Yao Yue, Efthalia Chatzisymeon, Ping Yang
Science of The Total Environment.2023; 905: 166994. CrossRef
The β-Lactamase Activity at the Community Level Confers β-Lactam Resistance to Bloom-Forming Microcystis aeruginosa Cells
Yerim Park, Wonjae Kim, Minkyung Kim, Woojun Park
Journal of Microbiology.2023; 61(9): 807. CrossRef
Bactericidal activity of silver nanoparticles in drug-resistant bacteria
C. Chapa González, L. I. González García, L. G. Burciaga Jurado, A. Carrillo Castillo
Brazilian Journal of Microbiology.2023; 54(2): 691. CrossRef
Computational modelling of epithelial cell monolayers during infection with Listeria monocytogenes
Raul Aparicio-Yuste, Francisco Serrano-Alcalde, Marie Muenkel, Jose Manuel Garcia-Aznar, Effie E. Bastounis, Maria Jose Gomez-Benito
Computer Methods in Applied Mechanics and Engineering.2022; 401: 115477. CrossRef
Gold nanoparticle-DNA aptamer-assisted delivery of antimicrobial peptide effectively inhibits Acinetobacter baumannii infection in mice
Jaeyeong Park, Eunkyoung Shin, Ji-Hyun Yeom, Younkyung Choi, Minju Joo, Minho Lee, Je Hyeong Kim, Jeehyeon Bae, Kangseok Lee
Journal of Microbiology.2022; 60(1): 128. CrossRef
Antibiotic resistome in a large urban-lake drinking water source in middle China: Dissemination mechanisms and risk assessment
Maozhen Han, Lu Zhang, Na Zhang, Yujie Mao, Zhangjie Peng, Binbin Huang, Yan Zhang, Zhi Wang
Journal of Hazardous Materials.2022; 424: 127745. CrossRef
Occurrence of antibiotic resistance genes and multidrug-resistant bacteria during wastewater treatment processes
Mingyeong Kang, Jihye Yang, Suhyun Kim, Jaeeun Park, Misung Kim, Woojun Park
Science of The Total Environment.2022; 811: 152331. CrossRef
Occurrence and spread of antibiotic-resistant bacteria on animal farms and in their vicinity in Poland and Ukraine—review
Karolina Jeżak, Anna Kozajda
Environmental Science and Pollution Research.2022; 29(7): 9533. CrossRef
Application of Electrochemical Oxidation for the Enhancement of Antibiotic Resistant Bacteria Removal in Stormwater Bioretention Cells
XiaoJun Zuo, SongHu Zhang, FanXin Kong, QiangQiang Xu
SSRN Electronic Journal .2022;[Epub] CrossRef
Exploration of the presence and abundance of multidrug resistance efflux genes in oil and gas environments
Damon C. Brown, Naomi Aggarwal, Raymond J. Turner
Microbiology .2022;[Epub] CrossRef
Small Things Matter: The 11.6-kDa TraB Protein is Crucial for Antibiotic Resistance Transfer Among Enterococci
Tamara M.I. Berger, Claudia Michaelis, Ines Probst, Theo Sagmeister, Lukas Petrowitsch, Sandra Puchner, Tea Pavkov-Keller, Bernd Gesslbauer, Elisabeth Grohmann, Walter Keller
Frontiers in Molecular Biosciences.2022;[Epub] CrossRef
The microbiome and its association with antibiotic resistance genes in the hadal biosphere at the Yap Trench
Hualong Su, Chengcheng Wu, Peiyun Han, Zixuan Liu, Mincong Liang, Zheng Zhang, Zhike Wang, Guangyu Guo, Xinyi He, Jianhu Pang, Cheng Wang, Shaoping Weng, Jianguo He
Journal of Hazardous Materials.2022; 439: 129543. CrossRef

Journal Article

The effects of deletion of cellobiohydrolase genes on carbon source-dependent growth and enzymatic lignocellulose hydrolysis in Trichoderma reesei: Meibin Ren , Yifan Wang , Guoxin Liu , Bin Zuo , Yuancheng Zhang , Yunhe Wang , Weifeng Liu , Xiangmei Liu , Yaohua Zhong; J. Microbiol. 2020;58(8):687-695. Published online June 10, 2020; DOI: https://doi.org/10.1007/s12275-020-9630-5

55 View
0 Download
8 Web of Science
8 Crossref

Abstract

The saprophytic fungus Trichoderma reesei has long been used as a model to study microbial degradation of lignocellulosic biomass. The major cellulolytic enzymes of T. reesei are the cellobiohydrolases CBH1 and CBH2, which constitute more than 70% of total proteins secreted by the fungus. However, their physiological functions and effects on enzymatic hydrolysis of cellulose substrates are not sufficiently elucidated. Here, the cellobiohydrolase-encoding genes cbh1 and cbh2 were deleted, individually or combinatively, by using an auxotrophic marker-recycling technique in T. reesei. When cultured on media with different soluble carbon sources, all three deletion strains (Δcbh1, Δcbh2, and Δcbh1Δcbh2) exhibited no dramatic variation in morphological phenotypes, but their growth rates increased apparently when cultured on soluble cellulase-inducing carbon sources. In addition, Δcbh1 showed dramatically reduced growth and Δcbh1Δcbh2 could hardly grew on microcrystalline cellulose (MCC), whereas all strains grew equally on sodium carboxymethyl cellulose (CMC-Na), suggesting that the influence of the CBHs on growth was carbon source-dependent. Moreover, five representative cellulose substrates were used to analyse the influence of the absence of CBHs on saccharification efficiency. CBH1 deficiency significantly affected the enzymatic hydrolysis rates of various cellulose substrates, where acid pre-treated corn stover (PCS) was influenced the least. CBH2 deficiency reduced the hydrolysis of MCC, PCS, and acid pre-treated and delignified corncob but improved the hydrolysis ability of filter paper. These results demonstrate the specific contributions of CBHs to the hydrolysis of different types of biomass, which could facilitate the development of tailor-made strains with highly efficient hydrolysis enzymes for certain biomass types in the biofuel industry.

Citations

Citations to this article as recorded by

An efficient CRISPR/Cas9 genome editing system based on a multiple sgRNA processing platform in Trichoderma reesei for strain improvement and enzyme production
Jiaxin Zhang, Kehang Li, Yu Sun, Cheng Yao, Weifeng Liu, Hong Liu, Yaohua Zhong
Biotechnology for Biofuels and Bioproducts.2024;[Epub] CrossRef
Transcriptome-wide analysis of a superior xylan degrading isolate Penicillium oxalicum 5–18 revealed active lignocellulosic degrading genes
Shuang Hu, Pei Han, Bao-Teng Wang, Long Jin, Hong-Hua Ruan, Feng-Jie Jin
Archives of Microbiology.2024;[Epub] CrossRef
Engineering the secretome of Aspergillus niger for cellooligosaccharides production from plant biomass
Fernanda Lopes de Figueiredo, Fabiano Jares Contesini, César Rafael Fanchini Terrasan, Jaqueline Aline Gerhardt, Ana Beatriz Corrêa, Everton Paschoal Antoniel, Natália Sayuri Wassano, Lucas Levassor, Sarita Cândida Rabelo, Telma Teixeira Franco, Uffe Hasb
Microbial Cell Factories.2024;[Epub] CrossRef
Constitutive overexpression of cellobiohydrolase 2 in Trichoderma reesei reveals its ability to initiate cellulose degradation
Yubo Wang, Meibin Ren, Yifan Wang, Lu Wang, Hong Liu, Mei Shi, Yaohua Zhong
Engineering Microbiology.2023; 3(1): 100059. CrossRef
Inducer-free recombinant protein production in Trichoderma reesei: secretory production of endogenous enzymes and heterologous nanobodies using glucose as the sole carbon source
Toshiharu Arai, Mayumi Wada, Hiroki Nishiguchi, Yasushi Takimura, Jun Ishii
Microbial Cell Factories.2023;[Epub] CrossRef
The Influence of Trctf1 Gene Knockout by CRISPR–Cas9 on Cellulase Synthesis by Trichoderma reesei with Various Soluble Inducers
Yudian Chen, Yushan Gao, Zancheng Wang, Nian Peng, Xiaoqin Ran, Tingting Chen, Lulu Liu, Yonghao Li
Fermentation.2023; 9(8): 746. CrossRef
The effect of cellobiohydrolase 1 gene knockout for composition and hydrolytic activity of the enzyme complex secreted by filamentous fungus Penicillium verruculosum
Valeriy Yu. Kislitsin, Andrey M. Chulkin, Ivan N. Zorov, Yuri А. Denisenko, Arkadiy P. Sinitsyn, Alexandra M. Rozhkova
Bioresource Technology Reports.2022; 18: 101023. CrossRef
Deciphering the efficient cellulose degradation by the thermophilic fungus Myceliophthora thermophila focused on the synergistic action of glycoside hydrolases and lytic polysaccharide monooxygenases
Xing Qin, Jiahuan Zou, Kun Yang, Jinyang Li, Xiaolu Wang, Tao Tu, Yuan Wang, Bin Yao, Huoqing Huang, Huiying Luo
Bioresource Technology.2022; 364: 128027. CrossRef

Research Support, Non-U.S. Gov't

Genetic Characterization of the Escherichia coli O66 Antigen and Functional Identification of its wzy Gene: Jiansong Cheng , Bin Liu , David A. Bastin , Weiqing Han , Lei Wang , Lu Feng; J. Microbiol. 2007;45(1):69-74.; DOI: https://doi.org/2488 [pii]

40 View
0 Download

Abstract: Escherichia coli is a clonal species, and occurs as both commensal and pathogenic strains, which are normally classified on the basis of their O, H, and K antigens. The O-antigen (O-specific polysaccharide), which consists of a series of oligosaccharide (O-unit) repeats, contributes major antigenic variability to the cell surface. The O-antigen gene cluster of E. coli O66 was sequenced in this study. The genes putatively responsible for the biosynthesis of dTDP-6-deoxy-L-talose and GDP-mannose, as well as those responsible for the transfer of sugars and for O-unit processing were identified based on their homology. The function of the wzy gene was confirmed by the results of a mutation test. Genes specific for E. coli O66 were identified via PCR screening against representatives of 186 E. coli and Shigella O type strains. The comparison of intergenic sequences located between galF and the O-antigen gene cluster in a range of E. coli and Shigella showed that this region may perform an important function in the homologous recombination of the O-antigen gene clusters.

First
Prev
Page of 1
Next
Last

Search