Journal of Microbiology

Review

Fecal Microbiota Transplantation: Indications, Methods, and Challenges.: Jee Young Lee, Yehwon Kim, Jiyoun Kim, Jiyeun Kate Kim; J. Microbiol. 2024;62(12):1057-1074. Published online November 18, 2024; DOI: https://doi.org/10.1007/s12275-024-00184-3

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Over the past two decades, as the importance of gut microbiota to human health has become widely known, attempts have been made to treat diseases by correcting dysbiosis of gut microbiota through fecal microbiota transplantation (FMT). Apart from current knowledge of gut microbiota, FMT to treat disease has a long history, from the treatment of food poisoning in the fourth century to the treatment of Clostridioides difficile infections in the twentieth century. In 2013, FMT was recognized as a standard treatment for recurrent C. difficile because it consistently showed high efficacy. Though recurrent C. difficile is the only disease internationally recognized for FMT efficacy, FMT has been tested for other diseases and shown some promising preliminary results. Different FMT methods have been developed using various formulations and administration routes. Despite advances in FMT, some issues remain to be resolved, such as donor screening, manufacturing protocols, and unknown components in the fecal microbiota. In this review, we discuss the mechanisms, clinical indications, methods, and challenges of current FMT. We also discuss the development of alternative therapies to overcome the challenges of FMT.

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Transplantation of Fecal Flora from Patients with Atherosclerosis to Mice Can Increase Serum Low-Density Lipoprotein Cholesterol and Affect Intestinal Flora and Its Metabolites
Liang Feng, Jianting Feng, Li He, Fu Chen, Xin Feng, Suwen Wang
Applied Microbiology.2025; 5(1): 29. CrossRef

Journal Articles

Transcription Factors Tec1 and Tec2 Play Key Roles in the Hyphal Growth and Virulence of Mucor lusitanicus Through Increased Mitochondrial Oxidative Metabolism: Viridiana Alejandre-Castañeda , J. Alberto Patiño-Medina , Marco I. Valle-Maldonado , Alexis García , Rafael Ortiz-Alvarado , León F. Ruíz-Herrera , Karla Viridiana Castro-Cerritos , Joel Ramírez-Emiliano , Martha I. Ramírez-Díaz , Victoriano Garre , Soo Chan Lee , Víctor Meza-Carmen; J. Microbiol. 2023;61(12):1043-1062. Published online December 19, 2023; DOI: https://doi.org/10.1007/s12275-023-00096-8

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Abstract

Mucormycosis is a lethal and difficult-to-treat fungal infection caused by fungi of the order Mucorales. Mucor lusitanicus, a member of Mucorales, is commonly used as a model to understand disease pathogenesis. However, transcriptional control of hyphal growth and virulence in Mucorales is poorly understood. This study aimed to investigate the role of Tec proteins, which belong to the TEA/ATTS transcription factor family, in the hyphal development and virulence of M. lusitanicus. Unlike in the genome of Ascomycetes and Basidiomycetes, which have a single Tec homologue, in the genome of Mucorales, two Tec homologues, Tec1 and Tec2, were found, except in that of Phycomyces blakesleeanus, with only one Tec homologue. tec1 and tec2 overexpression in M. lusitanicus increased mycelial growth, mitochondrial content and activity, expression of the rhizoferrin synthetase-encoding gene rfs, and virulence in nematodes and wax moth larvae but decreased cAMP levels and protein kinase A (PKA) activity. Furthermore, tec1- and tec2-overexpressing strains required adequate mitochondrial metabolism to promote the virulent phenotype. The heterotrimeric G beta subunit 1-encoding gene deletant strain (Δgpb1) increased cAMP-PKA activity, downregulation of both tec genes, decreased both virulence and hyphal development, but tec1 and tec2 overexpression restored these defects. Overexpression of allele-mutated variants of Tec1(S332A) and Tec2(S168A) in the putative phosphorylation sites for PKA increased both virulence and hyphal growth of Δgpb1. These findings suggest that Tec homologues promote mycelial development and virulence by enhancing mitochondrial metabolism and rhizoferrin accumulation, providing new information for the rational control of the virulent phenotype of M. lusitanicus.

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A one-pot five component reaction for the synthesis of tetrazol-benzofuran hybrids and their inhibitory activity against Mucor lusitanicus
Cesia M. Aguilar-Morales, Viridiana Alejandre-Castañeda, Claudia Contreras-Celedón, Martha Isela Ramírez-Díaz, Alejandro Islas-Jácome, Victor Meza-Carmen, Luis Chacón-García, Carlos J. Cortés-García
Organic & Biomolecular Chemistry.2024; 22(35): 7240. CrossRef
Functional characterization of two survival factor 1 genes in Mucor lusitanicus
Olivér Jáger, Csilla Szebenyi, Tammam Khaliefeh Siliman Abu Saleem, Anna Molnár, Vanda Kovács, Karina Kiss, Mónika Homa, Bernadett Vágó, Sándor Kiss-Vetráb, Mónika Varga, Rita Sinka, Csaba Vágvölgyi, Gábor Nagy, Tamás Papp, Renato Kovacs
Microbiology Spectrum.2024;[Epub] CrossRef

The Regulation of Phosphorus Release by Penicillium chrysogenum in Different Phosphate via the TCA Cycle and Mycelial Morphology: Liyan Wang , Da Tian , Xiaoru Zhang , Mingxue Han , Xiaohui Cheng , Xinxin Ye , Chaochun Zhang , Hongjian Gao , Zhen Li; J. Microbiol. 2023;61(8):765-775. Published online September 4, 2023; DOI: https://doi.org/10.1007/s12275-023-00072-2

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Abstract: Phosphate-solubilizing fungi (PSF) efficiently dissolve insoluble phosphates through the production of organic acids. This study investigates the mechanisms of organic acid secretion by PSF, specifically Penicillium chrysogenum, under tricalcium phosphate ( Ca3(PO4)2, Ca–P) and ferric phosphate ( FePO4, Fe–P) conditions. Penicillium chrysogenum exhibited higher phosphorus (P) release efficiency from Ca-P (693.6 mg/L) than from Fe–P (162.6 mg/L). However, Fe–P significantly enhanced oxalic acid (1193.7 mg/L) and citric acid (227.7 mg/L) production by Penicillium chrysogenum compared with Ca–P (905.7 and 3.5 mg/L, respectively). The presence of Fe–P upregulated the expression of genes and activity of enzymes related to the tricarboxylic acid cycle, including pyruvate dehydrogenase and citrate synthase. Additionally, Fe–P upregulated the expression of chitinase and endoglucanase genes, inducing a transformation of Penicillium chrysogenum mycelial morphology from pellet to filamentous. The filamentous morphology exhibited higher efficiency in oxalic acid secretion and P release from Fe–P and Ca–P. Compared with pellet morphology, filamentous morphology enhanced P release capacity by > 40% and > 18% in Ca–P and Fe–P, respectively. This study explored the strategies employed by PSF to improve the dissolution of different insoluble phosphates.

Description of Fervidibacillus gen. nov. with Two Species, Fervidibacillus albus sp. nov., and Fervidibacillus halotolerans sp. nov., Isolated from Tidal Flat Sediments and Emendation of Misclassificed Taxa in the Genus Caldibacillus: Sung&# , Mi&# , Hyun&# , Kae Kyoung Kwon; J. Microbiol. 2023;61(2):175-187. Published online February 17, 2023; DOI: https://doi.org/10.1007/s12275-023-00022-y

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Abstract

Two Gram-stain-positive, motile, endospore-forming, facultatively anaerobic strains, designated MEBiC13591T and MEBiC13594T, were isolated from tidal flat sediment of the Incheon City on the west coast of Korea. Growth of both novel strains was observed at pH 5–9 (optimum, pH 7–7.5), and in 0–8% NaCl (optimum, 2% for MEBiC13591T and 3% for MEBiC13594T). Strains MEBiC13591T and MEBiC13594T grew optimally at 50 °C, (37.5–56.1 °C) and 44 °C (20.7–50.7 °C), respectively. The main cellular fatty acids of strain MEBiC13591T were iso-C15: 0, anteiso-C15: 0, iso-C16: 0, iso-C17: 0 and anteiso-C17: 0, while those for strain MEBiC13594T were C14: 0, iso-C14: 0, iso-C15: 0, anteiso-C15: 0 and C16: 0. In both taxa, the major isoprenoid was MK-7. The genomic DNA G + C contents were 34.1 and 37.0 mol% for MEBiC13591T and MEBiC13594T, respectively. A 16S rRNA gene sequence analysis revealed that the novel strains showed high similarity with members of the genera Aeribacillus (95.0%) and Caldibacillus (93.5–94.5%); however, showed lower than 90% with Caldibacillus debilis TfT. Phylogenetic and Phylogenomic analysis revealed that two novel strains comprised distinct phyletic line with members formerly assigned to Caldibacillus. Based on genomic indices, such as AAI and ANI, members formerly affiliated with Caldibacillus and Bacillus as well as the novel strains should be classified into five independent genera. Based on the phenotypic, genomic and biochemical data, strains MEBiC13591T and MEBiC13594T represent two novel species in the novel genus, for which the names Fervidibacillus albus gen. nov., sp. nov. ( MEBiC13591T [= KCCM 43317T = KCTC 43181T = JCM 33662T = MCCC 1K04565T]), and Fervidibacillus halotolerans sp. nov. ( MEBiC13594T [= KCTC 43182T = JCM 34001T]) are proposed. Three additional genera Caldifermentibacillus, Palidibacillus, and Perspicuibacillus are also proposed by reclassification of the several species with valid names that formerly affiliated with the genera Caldibacillus.

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An update on novel taxa and revised taxonomic status of bacteria isolated from domestic companion and agricultural animals described in 2023
Sara D. Lawhon, Claire R. Burbick, Trinity Krueger, Elena Ruiz-Reyes, Erik Munson, Romney M. Humphries
Journal of Clinical Microbiology.2024;[Epub] CrossRef
Congregibacter variabilis sp. nov. and Congregibacter brevis sp. nov. Within the OM60/NOR5 Clade, Isolated from Seawater, and Emended Description of the Genus Congregibacter
Hyeonsu Tak, Miri S. Park, Hyerim Cho, Yeonjung Lim, Jang-Cheon Cho
Journal of Microbiology.2024; 62(9): 739. CrossRef
Validation List no. 213. Valid publication of new names and new combinations effectively published outside the IJSEM
Aharon Oren, Markus Göker
International Journal of Systematic and Evolutionary Microbiology .2023;[Epub] CrossRef

Predicting quorum sensing peptides using stacked generalization ensemble with gradient boosting based feature selection: Muthusaravanan Sivaramakrishnan , Rahul Suresh , Kannapiran Ponraj; J. Microbiol. 2022;60(7):756-765. Published online June 22, 2022; DOI: https://doi.org/10.1007/s12275-022-2044-9

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Abstract

Bacteria exist in natural environments for most of their life as complex, heterogeneous, and multicellular aggregates. Under these circumstances, critical cell functions are controlled by several signaling molecules known as quorum sensing (QS) molecules. In Gram-positive bacteria, peptides are deployed as QS molecules. The development of antibodies against such QS molecules has been identified as a promising therapeutic intervention for bacterial control. Hence, the identification of QS peptides has received considerable attention. Availability of a fast and reliable predictive model to effectively identify QS peptides can help the existing high throughput experiments. In this study, a stacked generalization ensemble model with Gradient Boosting Machine (GBM)-based feature selection, namely EnsembleQS was developed to predict QS peptides with high accuracy. On selected GBM features (791D), the EnsembleQS outperformed finely tuned baseline classifiers and demonstrated robust performance, indicating the superiority of the model. The accuracy of EnsembleQS is 4% higher than those resulting from ensemble model on hybrid dataset. When evaluating an independent data set of 40 QS peptides, the EnsembleQS model showed an accuracy of 93.4% with Matthew’s Correlation Coefficient (MCC) and area under the ROC curve (AUC) values 􀁇􀁇of 0.91 and 0.951, respectively. These
results
suggest that EnsembleQS will be a useful computational framework for predicting QS peptides and will efficiently support proteomics research. The source code and all datasets used in this study are publicly available at https:// github.com/proteinexplorers/EnsembleQS.

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Revolutionizing physics: a comprehensive survey of machine learning applications
Rahul Suresh, Hardik Bishnoi, Artem V. Kuklin, Atharva Parikh, Maxim Molokeev, R. Harinarayanan, Sarvesh Gharat, P. Hiba
Frontiers in Physics.2024;[Epub] CrossRef
DeepQSP: Identification of Quorum Sensing Peptides Through Neural Network Model
Md. Ashikur Rahman, Md. Mamun Ali, Kawsar Ahmed, Imran Mahmud, Francis M. Bui, Li Chen, Santosh Kumar, Mohammad Ali Moni
Results in Engineering.2024; 24: 102878. CrossRef
Computational tools for exploring peptide-membrane interactions in gram-positive bacteria
Shreya Kumar, Rex Devasahayam Arokia Balaya, Saptami Kanekar, Rajesh Raju, Thottethodi Subrahmanya Keshava Prasad, Richard K. Kandasamy
Computational and Structural Biotechnology Journal.2023; 21: 1995. CrossRef
DeepTPpred: A Deep Learning Approach With Matrix Factorization for Predicting Therapeutic Peptides by Integrating Length Information
Zhen Cui, Si-Guo Wang, Ying He, Zhan-Heng Chen, Qin-Hu Zhang
IEEE Journal of Biomedical and Health Informatics.2023; 27(9): 4611. CrossRef
PSRQSP: An effective approach for the interpretable prediction of quorum sensing peptide using propensity score representation learning
Phasit Charoenkwan, Pramote Chumnanpuen, Nalini Schaduangrat, Changmin Oh, Balachandran Manavalan, Watshara Shoombuatong
Computers in Biology and Medicine.2023; 158: 106784. CrossRef

Review

COVID-19 vaccine development based on recombinant viral and bacterial vector systems: combinatorial effect of adaptive and trained immunity: Mi-Hyun Lee , Bum-Joon Kim; J. Microbiol. 2022;60(3):321-334. Published online February 14, 2022; DOI: https://doi.org/10.1007/s12275-022-1621-2

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Abstract

Severe acute respiratory syndrome coronavirus 2 virus (SARSCoV- 2) infection, which causes coronavirus disease 2019 (COVID-19), has led to many cases and deaths worldwide. Therefore, a number of vaccine candidates have been developed to control the COVID-19 pandemic. Of these, to date, 21 vaccines have received emergency approval for human use in at least one country. However, the recent global emergence of SARS-CoV-2 variants has compromised the efficacy of the currently available vaccines. To protect against these variants, the use of vaccines that modulate T cell-mediated immune responses or innate immune cell memory function, termed trained immunity, is needed. The major advantage of a vaccine that uses bacteria or viral systems for the delivery of COVID-19 antigens is the ability to induce both T cell-mediated and humoral immune responses. In addition, such vaccine systems can also exert off-target effects via the vector itself, mediated partly through trained immunity; compared to other vaccine platforms, suggesting that this approach can provide better protection against even vaccine escape variants. This review presents the current status of the development of COVID-19 vaccines based on recombinant viral and bacterial delivery systems. We also discuss the current status of the use of licensed live vaccines for other infections, including BCG, oral polio and MMR vaccines, to prevent COVID-19 infections.

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Real-time infectious disease endurance indicator system for scientific decisions using machine learning and rapid data processing
Shivendra Dubey, Dinesh Kumar Verma, Mahesh Kumar
PeerJ Computer Science.2024; 10: e2062. CrossRef
What is the role of microbial biotechnology and genetic engineering in medicine?
Fernando Santos‐Beneit
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Previous BCG vaccination is associated with less severe clinical progression of COVID-19
Susan Martins Pereira, Florisneide Rodrigues Barreto, Ramon Andrade de Souza, Carlos Antonio de Souza Teles Santos, Marcos Pereira, Enny Santos da Paixão, Carla Cristina Oliveira de Jesus Lima, Marcio Santos da Natividade, Ana Angélica Bulcão Portela Lind
BMC Medicine.2023;[Epub] CrossRef
COVID-19 Incidence Proportion as a Function of Regional Testing Strategy, Vaccination Coverage, and Vaccine Type
Areg A. Totolian, Viacheslav S. Smirnov, Alexei A. Krasnov, Edward S. Ramsay, Vladimir G. Dedkov, Anna Y. Popova
Viruses.2023; 15(11): 2181. CrossRef
The Cellular and Epigenetic Aspects of Trained Immunity and Prospects for Creation of Universal Vaccines on the Eve of More Frequent Pandemics
I. V. Alekseenko, R. G. Vasilov, L. G. Kondratyeva, S. V. Kostrov, I. P. Chernov, E. D. Sverdlov
Russian Journal of Genetics.2023; 59(9): 851. CrossRef
Coronavirus XBB.1.5 as an Indicator of the Long-Term Continuation of the Covid-19 pandemic. What Next for Vaccination?
E. P. Kharchenko
Epidemiology and Vaccinal Prevention.2023; 22(2): 12. CrossRef
Extracellular Vesicle-Based SARS-CoV-2 Vaccine
Yasunari Matsuzaka, Ryu Yashiro
Vaccines.2023; 11(3): 539. CrossRef
Distinctive Combinations of RBD Mutations Contribute to Antibody Evasion in the Case of the SARS-CoV-2 Beta Variant
Tae-Hun Kim, Sojung Bae, Sunggeun Goo, Jinjong Myoung
Journal of Microbiology and Biotechnology.2023; 33(12): 1587. CrossRef
Leishmania tarentolae: a vaccine platform to target dendritic cells and a surrogate pathogen for next generation vaccine research in leishmaniases and viral infections
Claudio Bandi, Jairo Alfonso Mendoza-Roldan, Domenico Otranto, Alessandro Alvaro, Viviane Noll Louzada-Flores, Massimo Pajoro, Ilaria Varotto-Boccazzi, Matteo Brilli, Alessandro Manenti, Emanuele Montomoli, Gianvincenzo Zuccotti, Sara Epis
Parasites & Vectors.2023;[Epub] CrossRef
Cellular and Epigenetic Aspects of Trained Immunity and Prospects for Creation of Universal Vaccines in the Face of Increasingly Frequent Pandemics
I. V. Alekseenko, R. G. Vasilov, L. G. Kondratyeva, S. V. Kostrov, I. P. Chernov, E. D. Sverdlov
Генетика.2023; 59(9): 981. CrossRef
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Journal of Microbiology.2022; 60(3): 235. CrossRef

Journal Articles

Effects of rehydration on physiological and transcriptional responses of a water-stressed rhizobium: Jie Zhu , Xin Jiang , Dawei Guan , Yaowei Kang , Li Li , Fengming Cao , Baisuo Zhao , Mingchao Ma , Ji Zhao , Jun Li; J. Microbiol. 2022;60(1):31-46. Published online November 26, 2021; DOI: https://doi.org/10.1007/s12275-022-1325-7

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Abstract

As a microsymbiont of soybean, Bradyrhizobium japonicum plays an important role in symbiotic nitrogen fixation and sustainable agriculture. However, the survival of B. japonicum cells under water-deplete (e.g., drought) and water-replete (e.g., flood) conditions is a major concern affecting their nitrogen-fixing ability by establishing the symbiotic relationship with the host. In this study, we isolated a water stress tolerant rhizobium from soybean root nodules and tested its survival under water-deplete conditions. The rhizobium was identified as Bradyrhizobium japonicum and named strain 5038. Interestingly, both plate counting and live/dead fluorescence staining assays indicate that a number of viable but non-culturable cells exist in the culture medium upon the rehydration process which could cause dilution stress. Bradyrhizobium japonicum 5038 cells increased production of exopolysaccharide (EPS) and trehalose when dehydrated, suggesting that protective responses were stimulated. As expected, cells reduced their production upon the subsequent rehydration. To examine differential gene expression of B. japonicum 5038 when exposed to water-deplete and subsequent waterreplete conditions, whole-genome transcriptional analysis was performed under 10% relative humidity (RH), and subsequent 100% RH, respectively. A total of 462 differentially expressed genes (DEGs, > 2.0-fold) were identified under the 10% RH condition, while 3,776 genes showed differential expression during the subsequent rehydration (100% RH) process. Genes involved in signal transduction, inorganic ion transport, energy production and metabolisms of carbohydrates, amino acids, and lipids were far more up-regulated than downregulated in the 10% RH condition. Notably, trehalose biosynthetic genes (otsAB, treS, and treYZ), genes ligD, oprB, and a sigma factor rpoH were significantly induced by 10% RH. Under the subsequent 100% RH condition, genes involved in transcription, translation, cell membrane regulation, replication and repair, and protein processing were highly up-regulated. Interestingly, most of 10%-RH inducible genes displayed rehydration-repressed, except three genes encoding heat shock (Hsp20) proteins. Therefore, this study provides molecular evidence for the switch of gene expression of B. japonicum cells when encountered the opposite water availability from water-deplete to water-replete conditions.

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Challenges to rhizobial adaptability in a changing climate: Genetic engineering solutions for stress tolerance
Yunjia Zhang, Yee-Shan Ku, Tsz-Yan Cheung, Sau-Shan Cheng, Dawei Xin, Kewin Gombeau, Yizhi Cai, Hon-Ming Lam, Ting-Fung Chan
Microbiological Research.2024; 288: 127886. CrossRef
Plant–Soil Microbial Interaction: Differential Adaptations of Beneficial vs. Pathogenic Bacterial and Fungal Communities to Climate-Induced Drought
Nataliya Loiko, M. Nazrul Islam
Agronomy.2024; 14(9): 1949. CrossRef
Bacteria undergo significant shifts while archaea maintain stability in Pocillopora damicornis under sustained heat stress
Huimin Ju, Jian Zhang, Yiyang Zou, Feiyang Xie, Xiaoyu Tang, Si Zhang, Jie Li
Environmental Research.2024; 250: 118469. CrossRef
Effect of Nitrogen Application and Cutting Frequency on the Yield and Forage Quality of Alfalfa in Seasonal Cultivation
Kun Zhang, Chenyuan Zhai, Yonglong Li, Yan Li, Hui Qu, Yixin Shen
Agriculture.2023; 13(5): 1063. CrossRef
Profound Change in Soil Microbial Assembly Process and Co-occurrence Pattern in Co-inoculation of Bradyrhizobium japonicum 5038 and Bacillus aryabhattai MB35-5 on Soybean
Yubin Zhao, Dawei Guan, Xu Liu, Gui-Feng Gao, Fangang Meng, Bingqiang Liu, Pengfei Xing, Xin Jiang, Mingchao Ma, Fengming Cao, Li Li, Jun Li
Frontiers in Microbiology.2022;[Epub] CrossRef

Structure of bacterial and eukaryote communities reflect in situ controls on community assembly in a high-alpine lake: Eli Michael S. Gendron , John L. Darcy , Katherinia Hell , Steven K. Schmidt; J. Microbiol. 2019;57(10):852-864. Published online August 3, 2019; DOI: https://doi.org/10.1007/s12275-019-8668-8

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Abstract

Recent work suggests that microbial community composition in high-elevation lakes is significantly influenced by microbes entering from upstream terrestrial and aquatic habitats. To test this idea, we conducted 18S and 16S rDNA surveys of microbial communities in a high-alpine lake in the Colorado Rocky Mountains. We compared the microbial community of the lake to water entering the lake and to uphill soils that drain into the lake. Utilizing hydrological and abiotic data, we identified potential factors controlling microbial diversity and community composition. Results show a diverse community entering the lake at the inlet with a strong resemblance to uphill terrestrial and aquatic communities. In contrast, the lake communities (water column and outlet) showed significantly lower diversity and were significantly different from the inlet communities. Assumptions of neutral community assembly poorly predicted community differences between the inlet and lake, whereas “variable selection” and “dispersal limitation” were predicted to dominate. Similarly, the lake communities were correlated with discharge rate, indicating that longer hydraulic residence times limit dispersal, allowing selective pressures within the lake to structure communities. Sulfate and inorganic nitrogen and phosphorus concentrations correlated with community composition, indicating “bottom up” controls on lake community assembly. Furthermore, bacterial community composition was correlated with both zooplankton density and eukaryotic community composition, indicating biotic controls such as “top-down” interactions also contribute to community assembly in the lake. Taken together, these community analyses suggest that deterministic biotic and abiotic selection within the lake coupled with dispersal limitation structures the microbial communities in Green Lake 4.

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Unraveling the distribution pattern and driving forces of soil microorganisms under geographic barriers
Gu Rao, Wen-Long Song, Shu-Zhen Yan, Shuang-Lin Chen, John R. Spear
Applied and Environmental Microbiology.2024;[Epub] CrossRef
The nature of microbial diversity and assembly in the Nebraska Sandhills depends on organismal identity and habitat type
Kaitlin Gattoni, Eli M. S. Gendron, J. Parr McQueen, Kirsten Powers, Thomas O. Powers, Mary J. Harner, Jessica R. Corman, Dorota L. Porazinska
Community Ecology.2024;[Epub] CrossRef
Lakes-scale pattern of eukaryotic phytoplankton diversity and assembly process shaped by electrical conductivity in central Qinghai-Tibet Plateau
Huan Zhu, Xiong Xiong, Benwen Liu, Guoxiang Liu
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Free-Living and Particle-Associated Microbial Communities of Lake Baikal Differ by Season and Nutrient Intake
Maria Bashenkhaeva, Yelena Yeletskaya, Irina Tomberg, Artyom Marchenkov, Lubov Titova, Yuri Galachyants
Diversity.2023; 15(4): 572. CrossRef
Conservation tillage and moderate nitrogen application changed the composition, assembly pattern and interaction network of abundant and rare microbial community on straw surface
Houping Zhang, Yuanpeng Zhu, Chaoyang Yu, Yuze Li, Mei Long, Wei Li, Yuncheng Liao, Weiyan Wang, Xiaoxia Wen
Applied Soil Ecology.2023; 191: 105060. CrossRef
Sediment sulfate content determines assembly processes and network stability of bacteria communities of coastal land-based shrimp aquaculture ponds
Lianzuan Wu, Ping Yang, Linhai Zhang, Liangjuan Luo, Yan Hong, Wanyi Zhu, Lidi Zheng, Guanghui Zhao, Chuan Tong, Josep Peñuelas
Aquaculture.2023; 563: 738953. CrossRef
Microbial predators form a new supergroup of eukaryotes
Denis V. Tikhonenkov, Kirill V. Mikhailov, Ryan M. R. Gawryluk, Artem O. Belyaev, Varsha Mathur, Sergey A. Karpov, Dmitry G. Zagumyonnyi, Anastasia S. Borodina, Kristina I. Prokina, Alexander P. Mylnikov, Vladimir V. Aleoshin, Patrick J. Keeling
Nature.2022; 612(7941): 714. CrossRef
Crossing Treeline: Bacterioplankton Communities of Alpine and Subalpine Rocky Mountain Lakes
Kim Vincent, Hannah Holland-Moritz, Adam J. Solon, Eli M. S. Gendron, Steven K. Schmidt
Frontiers in Microbiology.2022;[Epub] CrossRef
Community Assembly and Co-occurrence Patterns Underlying the Core and Satellite Bacterial Sub-communities in the Tibetan Lakes
Qi Yan, Jianming Deng, Feng Wang, Yongqin Liu, Keshao Liu
Frontiers in Microbiology.2021;[Epub] CrossRef
Microbial community and abiotic effects on aquatic bacterial communities in north temperate lakes
Javad Sadeghi, Subba Rao Chaganti, Abdolrazagh Hashemi Shahraki, Daniel D. Heath
Science of The Total Environment.2021; 781: 146771. CrossRef
Evidence for phosphorus limitation in high-elevation unvegetated soils, Niwot Ridge, Colorado
Clifton P. Bueno de Mesquita, Laurel M. Brigham, Pacifica Sommers, Dorota L. Porazinska, Emily C. Farrer, John L. Darcy, Katharine N. Suding, Steven K. Schmidt
Biogeochemistry.2020; 147(1): 1. CrossRef

Co-occurrence patterns between phytoplankton and bacterioplankton across the pelagic zone of Lake Baikal during spring: Ivan S. Mikhailov , Yuri S. Bukin , Yulia R. Zakharova , Marina V. Usoltseva , Yuri P. Galachyants , Maria V. Sakirko , Vadim V. Blinov , Yelena V. Likhoshway; J. Microbiol. 2019;57(4):252-262. Published online March 30, 2019; DOI: https://doi.org/10.1007/s12275-019-8531-y

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Abstract

Phytoplankton and bacterioplankton play a key role in carbon cycling of aquatic ecosystems. In this study, we found that co-occurrence patterns between different types of phytoplankton, bacterioplankton, and environmental parameters in Lake Baikal during spring were different over the course of three consecutive years. The composition of phytoplankton and bacterial communities was investigated using microscopy and 16S rRNA gene pyrosequencing, respectively. Non-metric multidimensional scaling (NMDS) revealed a relationship between the structure of phytoplankton and bacterial communities and temperature, location, and sampling year. Associations of bacteria with diatoms, green microalgae, chrysophyte, and cryptophyte were identified using microscopy. Cluster analysis revealed similar correlation patterns between phytoplankton abundance, number of attached bacteria, ratio of bacteria per phytoplankton cell and environmental parameters. Positive and negative correlations between different species of phytoplankton, heterotrophic bacteria and environmental parameters may indicate mutualistic or competitive relationships between microorganisms and their preferences to the environment.

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Genomic Insights into the Bactericidal and Fungicidal Potential of Bacillus mycoides b12.3 Isolated in the Soil of Olkhon Island in Lake Baikal, Russia
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Review

REVIEW] H5 influenza, a global update: Rhodri Harfoot , Richard J. Webby; J. Microbiol. 2017;55(3):196-203. Published online February 28, 2017; DOI: https://doi.org/10.1007/s12275-017-7062-7

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Abstract

H5 influenza viruses have caused much alarm globally due to their high pathogenic potential. As yet we have not seen sustained spread of the virus amongst humans despite a high prevalence of the virus in avian populations. Nevertheless, isolated human cases of infection have demonstrated high mortality and there are substantial efforts being taken to monitor the evolution of the virus and to undertake preparedness activities. Here we review and discuss the evolution of the A/goose/Guangdong/1/96 (H5N1) virus with emphasis on recent events.

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Revista Argentina de Microbiología.2024;[Epub] CrossRef
Simultaneous Differential Detection of H5, H7, H9 and Nine NA Subtypes of Avian Influenza Viruses via a GeXP Assay
Sisi Luo, Zhixun Xie, Meng Li, Dan Li, Minxiu Zhang, Zhihua Ruan, Liji Xie, Sheng Wang, Qing Fan, Yanfang Zhang, Jiaoling Huang, Tingting Zeng
Microorganisms.2024; 12(1): 143. CrossRef
Multivalent next generation influenza virus vaccines protect against seasonal and pre-pandemic viruses
Naoko Uno, Ted M. Ross
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Recent Occurrence, Diversity, and Candidate Vaccine Virus Selection for Pandemic H5N1: Alert Is in the Air
Yordanka Medina-Armenteros, Daniela Cajado-Carvalho, Ricardo das Neves Oliveira, Milena Apetito Akamatsu, Paulo Lee Ho
Vaccines.2024; 12(9): 1044. CrossRef
Pigs are highly susceptible to but do not transmit mink-derived highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b
Taeyong Kwon, Jessie D. Trujillo, Mariano Carossino, Eu Lim Lyoo, Chester D. McDowell, Konner Cool, Franco S. Matias-Ferreyra, Trushar Jeevan, Igor Morozov, Natasha N. Gaudreault, Udeni B.R. Balasuriya, Richard J. Webby, Nikolaus Osterrieder, Juergen A. R
Emerging Microbes & Infections.2024;[Epub] CrossRef
Transmission dynamics of highly pathogenic avian influenza virus at the wildlife-poultry-environmental interface: A case study
Jolene A. Giacinti, Madeline Jarvis-Cross, Hannah Lewis, Jennifer F. Provencher, Yohannes Berhane, Kevin Kuchinski, Claire M. Jardine, Anthony Signore, Sarah C. Mansour, Denby E. Sadler, Brian Stevens, Natalie A. Prystajecky, Sailendra N. Sarma, Davor Ojk
One Health.2024; 19: 100932. CrossRef
On-Site and Visual Detection of the H5 Subtype Avian Influenza Virus Based on RT-RPA and CRISPR/Cas12a
Xu Zhou, Siwen Wang, Yue Ma, Yongping Jiang, Yanbing Li, Jianzhong Shi, Guohua Deng, Guobin Tian, Huihui Kong, Xiurong Wang
Viruses.2024; 16(5): 753. CrossRef
First Case of Highly Pathogenic Avian Influenza H5N1 in Montenegro
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Acta Veterinaria.2024; 74(1): 145. CrossRef
Self-Assembling Nanoparticle Hemagglutinin Influenza Vaccines Induce High Antibody Response
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International Journal of Molecular Sciences.2024; 25(13): 7259. CrossRef
Highly pathogenic avian influenza A (H5N1) in marine mammals and seabirds in Peru
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Nature Communications.2023;[Epub] CrossRef
Global review of the H5N8 avian influenza virus subtype
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Development and Validation of Competitive ELISA for Detection of H5 Hemagglutinin Antibodies
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Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China
Pengfei Cui, Jianzhong Shi, Congcong Wang, Yuancheng Zhang, Xin Xing, Huihui Kong, Cheng Yan, Xianying Zeng, Liling Liu, Guobin Tian, Chengjun Li, Guohua Deng, Hualan Chen
Emerging Microbes & Infections.2022; 11(1): 1693. CrossRef
Improved Subtyping of Avian Influenza Viruses Using an RT-qPCR-Based Low Density Array: ‘Riems Influenza a Typing Array’, Version 2 (RITA-2)
Kareem E. Hassan, Ann Kathrin Ahrens, Ahmed Ali, Magdy F. El-Kady, Hafez M. Hafez, Thomas C. Mettenleiter, Martin Beer, Timm Harder
Viruses.2022; 14(2): 415. CrossRef
Genetic evolution of hemagglutinin and neuraminidase genes of H5N1 highly pathogenic avian influenza viruses in Thailand
Pirom Noisumdaeng, Juthamas Phadungsombat, Sasrinakarn Weerated, Witthawat Wiriyarat, Pilaipan Puthavathana
PeerJ.2022; 10: e14419. CrossRef
H5N1 infection impairs the alveolar epithelial barrier through intercellular junction proteins via Itch-mediated proteasomal degradation
Tao Ruan, Yuling Sun, Jingting Zhang, Jing Sun, Wei Liu, Richard A. Prinz, Daxin Peng, Xiufan Liu, Xiulong Xu
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Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China
Pengfei Cui, Xianying Zeng, Xuyong Li, Yanbing Li, Jianzhong Shi, Conghui Zhao, Zhiyuan Qu, Yanwen Wang, Jing Guo, Wenli Gu, Qi Ma, Yuancheng Zhang, Weipeng Lin, Minghui Li, Jingman Tian, Dongxue Wang, Xin Xing, Yanjing Liu, Shuxin Pan, Yaping Zhang, Hong
Science China Life Sciences.2022; 65(4): 795. CrossRef
A broad spectrum HVT-H5 avian influenza vector vaccine which induces a rapid onset of immunity
Sylvia Reemers, Iwan Verstegen, Stephanie Basten, Willem Hubers, Saskia van de Zande
Vaccine.2021; 39(7): 1072. CrossRef
The genetics of highly pathogenic avian influenza viruses of subtype H5 in Germany, 2006–2020
Jacqueline King, Timm Harder, Franz J. Conraths, Martin Beer, Anne Pohlmann
Transboundary and Emerging Diseases.2021; 68(3): 1136. CrossRef
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Development and biochemical characterization of the monoclonal antibodies for specific detection of the emerging H5N8 and H5Nx avian influenza virus hemagglutinins
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Wild bird trade at live poultry markets potentiates risks of avian influenza virus introduction in Iran
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Nature Communications.2021;[Epub] CrossRef
Outbreak Severity of Highly Pathogenic Avian Influenza A(H5N8) Viruses Is Inversely Correlated to Polymerase Complex Activity and Interferon Induction
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Journal of Virology.2020;[Epub] CrossRef
Certainty of success: three critical parameters in coronavirus vaccine development
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Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses
Paul F. Horwood, Thomas Fabrizio, Srey Viseth Horm, Artem Metlin, Sopheaktra Ros, Songha Tok, Trushar Jeevan, Patrick Seiler, Phalla Y, Sareth Rith, Annika Suttie, Philippe Buchy, Erik A. Karlsson, Richard Webby, Philippe Dussart
Emerging Microbes & Infections.2020; 9(1): 1702. CrossRef
Effects and safety of Tanreqing injection on viral pneumonia: Retraction
Yue Qiu, Xue Pan, Lin Su, Hui Lui, Ya-Dong Li
Medicine.2020; 99(37): e22022. CrossRef
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Edris Shirvani, Berin P. Varghese, Anandan Paldurai, Siba K. Samal
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Anna Stachyra, Anna Góra-Sochacka, Jan P Radomski, Agnieszka Sirko
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Su He Wang, Douglas Smith, Zhengyi Cao, Jesse Chen, Hugo Acosta, Jessica A. Chichester, Vidadi Yusibov, Stephen J. Streatfield, Ali Fattom, James R. Baker
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Research Support, Non-U.S. Gov't

Structural insight for substrate tolerance to 2-deoxyribose-5-phosphate aldolase from the pathogen Streptococcus suis: Thinh-Phat Cao , Joong-Su Kim , Mi-Hee Woo , Jin Myung Choi , Youngsoo Jun , Kun Ho Lee , Sung Haeng Lee; J. Microbiol. 2016;54(4):311-321. Published online April 1, 2016; DOI: https://doi.org/10.1007/s12275-016-6029-4

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Abstract

2-deoxyribose-5-phosphate aldolase (DERA) is a class I aldolase that catalyzes aldol condensation of two aldehydes in the active site, which is particularly germane in drug manufacture. Structural and biochemical studies have shown that the active site of DERA is typically loosely packed and displays broader substrate specificity despite sharing conserved folding architecture with other aldolases. The most distinctive structural feature of DERA compared to other aldolases is short and flexible C-terminal region. This region is also responsible for substrate recognition. Therefore, substrate tolerance may be related to the C-terminal structural features of DERA. Here, we determined the crystal structures of full length and C-terminal truncated DERA from Streptococcus suis (SsDERA). In common, both contained the typical (α/β)8 TIM-barrel fold of class I aldolases. Surprisingly, C-terminal truncation
result
ing in missing the last α9 and β8 secondary elements, allowed DERA to maintain activity comparable to the fulllength enzyme. Specifically, Arg186 and Ser205 residues at the C-terminus appeared mutually supplemental or less indispensible for substrate phosphate moiety recognition. Our results suggest that DERA might adopt a shorter C-terminal region than conventional aldolases during evolution pathway, resulting in a broader range of substrate tolerance through active site flexibility.

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Review

Replicating poxviruses for human cancer therapy: Manbok Kim; J. Microbiol. 2015;53(4):209-218. Published online April 8, 2015; DOI: https://doi.org/10.1007/s12275-015-5041-4

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Abstract

Naturally occurring oncolytic viruses are live, replicationproficient viruses that specifically infect human cancer cells while sparing normal cell counterparts. Since the eradication of smallpox in the 1970s with the aid of vaccinia viruses, the vaccinia viruses and other genera of poxviruses have shown various degrees of safety and efficacy in pre-clinical or clinical application for human anti-cancer therapeutics. Furthermore, we have recently discovered that cellular tumor suppressor genes are important in determining poxviral oncolytic tropism. Since carcinogenesis is a multi-step process involving accumulation of both oncogene and tumor suppressor gene abnormalities, it is interesting that poxvirus can exploit abnormal cellular tumor suppressor signaling for its oncolytic specificity and efficacy. Many tumor suppressor genes such as p53, ATM, and RB are known to play important roles in genomic fidelity/maintenance. Thus, tumor suppressor gene abnormality could affect host genomic integrity and likely disrupt intact antiviral networks due to accumulation of genetic defects, which would in turn result in oncolytic virus susceptibility. This review outlines the characteristics of oncolytic poxvirus strains, including vaccinia, myxoma, and squirrelpox virus, recent progress in elucidating the molecular connection between oncogene/tumor suppressor gene abnormalities and poxviral oncolytic tropism, and the associated preclinical/clinical implications. I would also like to propose future directions in the utility of poxviruses for oncolytic virotherapy.

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Variations of SSU rDNA Group I Introns in Different Isolates of Cordyceps militaris and the Loss of an Intron during Cross-Mating: Tiantian Lian , Tao Yang , Junde Sun , Suping Guo , Huaijun Yang , Caihong Dong; J. Microbiol. 2014;52(8):659-666. Published online July 4, 2014; DOI: https://doi.org/10.1007/s12275-014-3681-4

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Abstract

Cordyceps militaris, the type species of genus Cordyceps, is one of the most popular mushrooms and a nutraceutical in eastern Asia. It is considered a model organism for the study of Cordyceps species because it can complete its life cycle when cultured in vitro. In the present study, the occurrence and sequence variation of SSU rDNA group I introns, Cmi.S943 and Cmi.S1199, among different isolates of C. militaris were analyzed. Based on the secondary structure predictions, the Cmi.S943 intron has been placed in subgroup IC1, and the Cmi.S1199 intron has been placed in subgroup IE. No significant similarity between Cmi.S943 and Cmi.S1199 suggested different origins. Three genotypes, based on the frequency and distribution of introns, were described to discriminate the 57 surveyed C. militaris strains. It was found that the genotype was related to the stroma characteristics. The stromata of all of the genotype II strains, which possessed only Cmi.S943, could produce perithecium. In contrast, the stromata of all genotype III strains, which had both Cmi.S943 and Cmi.S1199, could not produce perithecium. Cmi.S1199 showed the lowest level of intra-specific variation among the tested strains. Group I introns can be lost during strain cross-mating. Therefore, we presumed that during cross-mating and recombination, intron loss could be driven by positive Darwinian selection due to the energetic cost of transcribing long introns.

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Gohteikhimyces, a novel hyphomycete genus from submerged wood, based on three collections in Taiwan
Jie-Hao Ou, Sung-Yuan Hsieh, Chang-Hsin Kuo
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Entomopathogenicity of Ascomycete Fungus Cordyceps militaris on the Cotton Bollworm, Helicoverpa zea (Boddie) (Lepidoptera: Noctuidae)
James P. Glover, Marissa I. Nufer, Omaththage P. Perera, Maribel Portilla, Justin George
Journal of Fungi.2023; 9(6): 614. CrossRef
Comparison of mitochondrial genomes provides insights into intron dynamics and evolution in the caterpillar fungus Cordyceps militaris
Yongjie Zhang, Shu Zhang, Guozhen Zhang, Xingzhong Liu, Chengshu Wang, Jianping Xu
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Rhf1 gene is involved in the fruiting body production of Cordyceps militaris fungus
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NOTE] Is The Biotransformation of Chlorinated Dibenzo-p-dioxins by Sphingomonas wittichii RW1 Governed by Thermodynamic Factors?: In-Hyun Nam , Hyo-Bong Hong , Stefan Schmidt; J. Microbiol. 2014;52(9):801-804. Published online February 17, 2014; DOI: https://doi.org/10.1007/s12275-014-3424-6

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Abstract

Density functional theory (DFT) calculations were used to explore the relationship between the biotransformation of dibenzo-p-dioxin and selected chlorinated derivatives by resting cells of Sphingomonas wittichii RW1 and measuring the thermodynamic properties of the biotransformation substrates. Sphingomonas wittichii RW1 can aerobically catabolize dibenzo-p-dioxin as well as 2,7-dichloro-, 1,2,3-trichloro-, 1,2,3,4-tetrachloro-, and 1,2,3,4,7,8-hexachlorodibenzo-pdioxin; however, neither the 2,3,7-trichloro- nor the 1,2,3,7,8-pentachlorodibenzo-p-dioxin was transformed to its corresponding metabolic intermediate. The experimental biotransformation rates established were apparently governed by the selected thermodynamic properties of the substrates tested.

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Burning question: Rethinking organohalide degradation strategy for bioremediation applications
Qihong Lu, Qi Liang, Shanquan Wang
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Development of a two-stage washing and biodegradation system to remediate octachlorinated dibenzo-p-dioxin-contaminated soils
J. L. Lin, C. D. Dong, C. W. Chen, S. H. Chen, T. E. Hsieh, C. M. Kao
International Journal of Environmental Science and Technology.2017; 14(9): 1919. CrossRef
Aerobic bacterial catabolism of persistent organic pollutants — potential impact of biotic and abiotic interaction
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Bacterial Diversity and Composition of an Alkaline Uranium Mine Tailings-Water Interface: Nurul H. Khan , Viorica F. Bondici , Prabhakara G. Medihala , John R. Lawrence , Gideon M. Wolfaardt , Jeff Warner , Darren R. Korber; J. Microbiol. 2013;51(5):558-569. Published online September 14, 2013; DOI: https://doi.org/10.1007/s12275-013-3075-z

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Abstract

The microbial diversity and biogeochemical potential associated with a northern Saskatchewan uranium mine watertailings interface was examined using culture-dependent and -independent techniques. Morphologically-distinct colonies from uranium mine water-tailings and a reference lake (MC) obtained using selective and non-selective media were selected for 16S rRNA gene sequencing and identification, revealing that culturable organisms from the uranium tailings interface were dominated by Firmicutes and Betaproteobacteria; whereas, MC organisms mainly consisted of Bacteroidetes and Gammaproteobacteria. Ion Torrent (IT) 16S rRNA metagenomic analysis carried out on extracted DNA from tailings and MC interfaces demonstrated the dominance of Firmicutes in both of the systems. Overall, the tailings-water interface environment harbored a distinct bacterial community relative to the MC, reflective of the ambient conditions (i.e., total dissolved solids, pH, salinity, conductivity, heavy metals) dominating the uranium tailings system. Significant correlations among the physicochemical data and the major bacterial groups present in the tailings and MC were also observed. Presence of sulfate reducing bacteria demonstrated by culture-dependent analyses and the dominance of Desulfosporosinus spp. indicated by Ion Torrent analyses within the tailings-water interface suggests the existence of anaerobic microenvironments along with the potential for reductive metabolic processes.

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The remediation of uranium-contaminated groundwater via bioreduction coupled to biomineralization with different pH and electron donors
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Uday Kumar Banala, Nilamadhab Prasad Indradyumna Das, Subba Rao Toleti
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Jared Robertson, M. Jim Hendry, T. Kotzer, Kebbi A. Hughes
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Genhe He, Xiaodong Wang, Xu Liu, Xiaoyu Xiao, Shoucheng Huang, Jichun Wu
Russian Journal of Ecology.2018; 49(6): 524. CrossRef
Biogeochemical Importance of the Bacterial Community in Uranium Waste Deposited at Key Lake, Northern Saskatchewan
Viorica F. Bondici, George D. W. Swerhone, James J. Dynes, John R. Lawrence, Gideon M. Wolfaardt, Jeff Warner, Darren R. Korber
Geomicrobiology Journal.2016; 33(9): 807. CrossRef
Biogeochemical activity of microbial biofilms in the water column overlying uranium mine tailings
V.F. Bondici, N.H. Khan, G.D.W. Swerhone, J.J. Dynes, J.R. Lawrence, E. Yergeau, G.M. Wolfaardt, J. Warner, D.R. Korber
Journal of Applied Microbiology.2014; 117(4): 1079. CrossRef

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