Indole is an organic compound that is widespread in microbial
communities inhabiting diverse habitats, like the soil
environment and human intestines. Measurement of indole
production is a traditional method for the identification of
microbial species. Escherichia coli can produce millimolar
concentrations of indole in the stationary growth phase under
nutrient-rich conditions. Indole has received considerable
attention because of its remarkable effects on various
biological functions of the microbial communities, for example,
biofilm formation, motility, virulence, plasmid stability,
and antibiotic resistance. Indole may function as an
intercellular signaling molecule, like a quorum-sensing signal.
Nevertheless, a receptor system for indole and the function
of this compound in coordinated behavior of a microbial population
(which are requirements for a true signaling molecule)
have not yet been confirmed. Recent findings suggest
that a long-known quorum-sensing regulator, E. coli’s SdiA,
cannot recognize indole and that this compound may simply
cause membrane disruption and energy reduction, which
can lead to various changes in bacterial physiology including
unstable folding of a quorum-sensing regulator. Indole
appears to be responsible for acquisition of antibiotic resistance
via the formation of persister cells and activation of an
exporter. This review highlights and summarizes the current
knowledge about indole as a multitrophic molecule among
bacteria, together with recently identified new avenues of
research.
Citations
Citations to this article as recorded by
Integrative multi-omics analysis uncovers tumor-immune-gut axis influencing immunotherapy outcomes in ovarian cancer Spencer R. Rosario, Mark D. Long, Shanmuga Chilakapati, Eduardo Cortes Gomez, Sebastiano Battaglia, Prashant K. Singh, Jianmin Wang, Katy Wang, Kristopher Attwood, Suzanne M. Hess, AJ Robert McGray, Kunle Odunsi, Brahm H. Segal, Gyorgy Paragh, Song Liu, J Nature Communications.2024;[Epub] CrossRef
Integration of metagenome and metabolome analysis reveals the correlation of gut microbiota, oxidative stress, and inflammation in Coilia nasus under air exposure stress and salinity mitigation Yuqian Liu, Jun Gao, Zhijuan Nie, Jiayu Wang, Yi Sun, Gangchun Xu Comparative Biochemistry and Physiology Part D: Genomics and Proteomics.2024; 49: 101175. CrossRef
Auxin-mediated regulation of susceptibility to toxic metabolites, c-di-GMP levels, and phage infection in the rhizobacterium
Serratia plymuthica
Miriam Rico-Jiménez, Zulema Udaondo, Tino Krell, Miguel A. Matilla, Gilles P. van Wezel mSystems.2024;[Epub] CrossRef
Indole May Help the Horizontal Transmission of Antibiotic Resistance Genes in E. coli Under Subinhibitory Concentrations of Cefotaxime Stress Weiqi Dong, Panpan Du, Ruisen Huang, Shuoyan Lv, Hong Chen, Songlei Guan, Sushil Nagar Cellular Microbiology.2024;[Epub] CrossRef
Exogenous indole modulates several CpxRA-mediated virulence-related parameters of Edwardsiella piscicida in vitro Yin Gou, Qingjian Fang, Hanjie Gu, Aijun Tian, Jun Li, Yan Wang, Yonghua Hu Marine Life Science & Technology.2024; 6(4): 665. CrossRef
A UHPLC-QE-MS-based metabolomics approach for the evaluation of fermented lipase by an engineered
Escherichia coli
Jun Zhang, Ying Zhang, Wen Luo, Zhiyuan Wang, Pengmei Lv, Zhongming Wang Preparative Biochemistry & Biotechnology.2024; : 1. CrossRef
Multi-wavelength Fluorescence Monitoring of Faecal Contamination in Waters: A Laboratory-based Quantification Kane L. Offenbaume, Edoardo Bertone, Dechao Chen, Qin Li, Helen Stratton, Rodney A. Stewart Environmental Processes.2024;[Epub] CrossRef
Indole signaling enhances biofilm formation and quorum sensing in sequencing biofilm batch reactors Weize Wu, Jiawei Jing, Zhuo Chen, Xinyu Guo, Yuanyuan Qu Journal of Environmental Chemical Engineering.2024; 12(3): 112494. CrossRef
Unraveling the Dynamics of Host–Microbiota Indole Metabolism: An Investigation of Indole, Indolin-2-one, Isatin, and 3-Hydroxyindolin-2-one Arnas Kunevičius, Mikas Sadauskas, Julija Raudytė, Rolandas Meškys, Aurelijus Burokas Molecules.2024; 29(5): 993. CrossRef
Filters of automobile air conditioning systems as in-car source of exposure to infections and toxic moulds Małgorzata Gołofit-Szymczak, Angelina Wójcik-Fatla, Agata Stobnicka-Kupiec, Rafał L. Górny Environmental Science and Pollution Research.2023; 30(49): 108188. CrossRef
Efflux pumps and microbial biofilm formation Mahdyeh Neghabi Hajiagha, Hossein Samadi Kafil Infection, Genetics and Evolution.2023; 112: 105459. CrossRef
Indole inhibited the expression of csrA gene in Escherichia coli Jing Zheng, Guocai Zuo, Zhiguo Zhou, Zhenxia Shi, Huiying Guo, Zemin Sun, Yongjun Feng The Journal of General and Applied Microbiology.2023; 69(5): 239. CrossRef
The Synthesis and Biological Evaluation of 2-(1H-Indol-3-yl)quinazolin-4(3H)-One Derivatives Elena Y. Mendogralo, Larisa Y. Nesterova, Ekaterina R. Nasibullina, Roman O. Shcherbakov, Alexander G. Tkachenko, Roman Y. Sidorov, Maxim A. Sukonnikov, Dmitry A. Skvortsov, Maxim G. Uchuskin Molecules.2023; 28(14): 5348. CrossRef
The determination of the biological function of bacterial pink pigment and Fusarium chlamydosporum on alfalfa (Medicago sativa L.) Rong Huang, Hong Zhang, Haiyan Chen, Linxin He, Xiaoni Liu, Zhenfen Zhang Frontiers in Microbiology.2023;[Epub] CrossRef
Quorum sensing architecture network in Escherichia coli virulence and pathogenesis Celia Mayer, Anabela Borges, Saskia-Camille Flament-Simon, Manuel Simões FEMS Microbiology Reviews.2023;[Epub] CrossRef
Stable isotope-assisted metabolite profiling reveals new insights into L-tryptophan chemotrophic metabolism of Rubrivivax benzoatilyticus Shabbir Ahmad, Mujahid Mohammed, Lakshmi Prasuna Mekala, Rai Anusha, Chintalapati Sasikala, Chintalapati Venkata Ramana World Journal of Microbiology and Biotechnology.2023;[Epub] CrossRef
The recognition, control, and stress tolerance of bacterial persister cells Yoshimitsu Masuda Nippon Shokuhin Kagaku Kogaku Kaishi.2023; 70(8): 311. CrossRef
Pseudomonas aeruginosa Resists Phage Infection via Eavesdropping on Indole Signaling Guanhua Xuan, Qin Dou, Jiuna Kong, Hong Lin, Jingxue Wang, Ayush Kumar Microbiology Spectrum.2023;[Epub] CrossRef
A response regulator controls Acinetobacter baumannii virulence by acting as an indole receptor Binbin Cui, Quan Guo, Xia Li, Shihao Song, Mingfang Wang, Gerun Wang, Aixin Yan, Jianuan Zhou, Yinyue Deng, Marenda Wilson-Pham PNAS Nexus.2023;[Epub] CrossRef
Characterization of the IAA-Producing and -Degrading Pseudomonas Strains Regulating Growth of the Common Duckweed (Lemna minor L.) Tatjana Popržen, Ivan Nikolić, Dijana Krstić-Milošević, Branka Uzelac, Milana Trifunović-Momčilov, Marija Marković, Olga Radulović International Journal of Molecular Sciences.2023; 24(24): 17207. CrossRef
Metagenomic analysis reveals indole signaling effect on microbial community in sequencing batch reactors: Quorum sensing inhibition and antibiotic resistance enrichment Dai Chunxiao, Fang Ma, Weize Wu, Shuzhen Li, Jing Yang, Zhuo Chen, Shengyang Lian, Yuanyuan Qu Environmental Research.2023; 229: 115897. CrossRef
Proteomic analysis reveals the adaptation of Vibrio splendidus to an iron deprivation condition Huirong Yang, Huimin Song, Jinxia Zhang, Weisheng Li, Qingxi Han, Weiwei Zhang Applied Microbiology and Biotechnology.2023; 107(7-8): 2533. CrossRef
Bacterial quorum sensing orchestrates longitudinal interactions to shape microbiota assembly Ying Su, Ming-ying Xu, Ying Cui, Run-zhi Chen, Li-xiang Xie, Jing-xiang Zhang, Yong-qiu Chen, Tao Ding Microbiome.2023;[Epub] CrossRef
Synthetic bacterial therapies for intestinal diseases based on quorum-sensing circuits Zhuoce Dang, Mengxue Gao, Lina Wang, Jiahao Wu, Yufei Guo, Zhixin Zhu, He Huang, Guangbo Kang Biotechnology Advances.2023; 65: 108142. CrossRef
Production of indole and hydrogen sulfide by the oxygen-tolerant mutant strain Clostridium sp. Aeroto-AUH-JLC108 contributes to form a hypoxic microenvironment Yu-Xia Liu, Shi-Juan Dou, Meng Li, Xiu-Ling Wang Archives of Microbiology.2022;[Epub] CrossRef
Contribution of quorum sensing to virulence and antibiotic resistance in zoonotic bacteria Qingying Fan, Jing Zuo, Haikun Wang, Daniel Grenier, Li Yi, Yang Wang Biotechnology Advances.2022; 59: 107965. CrossRef
Quorum Sensing Orchestrates Antibiotic Drug Resistance, Biofilm Formation, and Motility in Escherichia coli and Quorum Quenching Activities of Plant-derived Natural Products: A Review Kevin Smith Puno Cabuhat, Llewelyn Sotto Moron-Espiritu Journal of Pure and Applied Microbiology.2022; 16(3): 1538. CrossRef
Bacterial survivors: evaluating the mechanisms of antibiotic persistence
Xiaoyi Shi, Ashraf Zarkan
Microbiology
.2022;[Epub] CrossRef
Characteristics of Bacterial Persister and Its Control Yoshimitsu MASUDA KAGAKU TO SEIBUTSU.2022; 60(5): 232. CrossRef
Quorum Sensing: A New Perspective to Reveal the Interaction Between Gut Microbiota and Host Lei Yang, Tian-jie Yuan, Yue Wan, Wen-wen Li, Chen Liu, Shu Jiang, Jin-ao Duan Future Microbiology.2022; 17(4): 293. CrossRef
Targeted and non-targeted analysis of young-of-year smallmouth bass using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry Paige Teehan, Megan K. Schall, Vicki S. Blazer, Frank L. Dorman Science of The Total Environment.2022; 806: 150378. CrossRef
Ribosome Hibernation: Molecular Strategy of Bacterial Survival (Review) E. A. Khaova, N. M. Kashevarova, A. G. Tkachenko Applied Biochemistry and Microbiology.2022; 58(3): 213. CrossRef
Indigo dyeing from Isatis tinctoria L.: From medieval to modern use Julia Mocquard, Anne-Cécile Le Lamer, Paul-Louis Fabre, Céline Mathieu, Clément Chastrette, Adrien Vitrai, Virginie Vandenbossche Dyes and Pigments.2022; 207: 110675. CrossRef
Gut Microbiota-Derived Indole-3-Carboxylate Influences Mucosal Integrity and Immunity Through the Activation of the Aryl Hydrocarbon Receptors and Nutrient Transporters in Broiler Chickens Challenged With Eimeria maxima Inkyung Park, Hyoyoun Nam, Doyun Goo, Samiru S. Wickramasuriya, Noah Zimmerman, Alexandra H. Smith, Thomas G. Rehberger, Hyun S. Lillehoj Frontiers in Immunology.2022;[Epub] CrossRef
Investigation of indole biodegradation by Cupriavidus sp. strain IDO with emphases on downstream biotransformation and indigo production Chunxiao Dai, Fang Ma, Qiao Ma, Jing Yang, Yan Li, Bingyu Yang, Yuanyuan Qu Environmental Science and Pollution Research.2022; 29(6): 8369. CrossRef
Production of Indole and Indole-Related Compounds by the Intestinal Microbiota and Consequences for the Host: The Good, the Bad, and the Ugly Naouel Tennoune, Mireille Andriamihaja, François Blachier Microorganisms.2022; 10(5): 930. CrossRef
Multidrug-Resistant Biofilm, Quorum Sensing, Quorum Quenching, and Antibacterial Activities of Indole Derivatives as Potential Eradication Approaches Ayodele T. Odularu, Anthony J. Afolayan, Alexander P. Sadimenko, Peter A. Ajibade, Johannes Z. Mbese, Maria Bayliak BioMed Research International.2022; 2022: 1. CrossRef
Indole Facilitates Antimicrobial Uptake in Bacteria Tong Wu, Michael J. Wilhelm, Yujie Li, Jianqiang Ma, Hai-Lung Dai ACS Infectious Diseases.2022; 8(6): 1124. CrossRef
Mechanisms of Inhibition of Quorum Sensing as an Alternative for the Control of E. coli and Salmonella Esmeralda Escobar-Muciño, Margarita M. P. Arenas-Hernández, M. Lorena Luna-Guevara Microorganisms.2022; 10(5): 884. CrossRef
Role of alarmone (p)ppGpp in the regulation of indole formation depending on glucose content in Escherichia coli N. M. Kashevarova, A. V. Akhova, E. A. Khaova, A. G. Tkachenko Acta Biomedica Scientifica.2022; 7(3): 162. CrossRef
Bacterial Long-Range Warfare: Aerial Killing of Legionella pneumophila by Pseudomonas fluorescens Marie-Hélène Corre, Anne Mercier, Mathilde Bouteiller, Alix Khalil, Christophe Ginevra, Ségolène Depayras, Charly Dupont, Meg Rouxel, Mathias Gallique, Laettitia Grac, Sophie Jarraud, David Giron, Annabelle Merieau, Jean-Marc Berjeaud, Julien Verdon, Joan Microbiology Spectrum.2021;[Epub] CrossRef
Anti-biofilm ability of garlic extract on Pantoea agglomerans and application to biosand filter Seul Jin, Ji Hun Park, Woong-Suk Yang, Jae-Yong Lee, Cher-Won Hwang Desalination and Water Treatment.2021; 228: 84. CrossRef
A high‐throughput genetically directed protein crosslinking analysis reveals the physiological relevance of the ATP synthase ‘inserted’ state Yang Liu, Jiayu Yu, Mengyuan Wang, Qingfang Zeng, Xinmiao Fu, Zengyi Chang The FEBS Journal.2021; 288(9): 2989. CrossRef
The Microbiota and the Gut–Brain Axis in Controlling Food Intake and Energy Homeostasis Marina Romaní-Pérez, Clara Bullich-Vilarrubias, Inmaculada López-Almela, Rebeca Liébana-García, Marta Olivares, Yolanda Sanz International Journal of Molecular Sciences.2021; 22(11): 5830. CrossRef
The Effects of Indole on Intracellular Polyamine Content and Antibiotic Susceptibility of Escherichia coli L. Y. Nesterova, A. V. Akhova, A. G. Tkachenko Moscow University Biological Sciences Bulletin.2021; 76(4): 196. CrossRef
Potential of Herbaspirillum and Azospirillum Consortium to Promote Growth of Perennial Ryegrass under Water Deficit Sandra Cortés-Patiño, Christian Vargas, Fagua Álvarez-Flórez, Ruth Bonilla, German Estrada-Bonilla Microorganisms.2021; 9(1): 91. CrossRef
New Insights Into Gut-Bacteria-Derived Indole and Its Derivatives in Intestinal and Liver Diseases Xiaojing Li, Binbin Zhang, Yiyang Hu, Yu Zhao Frontiers in Pharmacology.2021;[Epub] CrossRef
The cytidine repressor regulates the survival of Pantoea agglomerans YS19 under oxidative stress and sulfur starvation conditions Jiajia Yu, Mengqi Jia, Yongjun Feng The Journal of General and Applied Microbiology.2021; 67(2): 59. CrossRef
The classification of bacterial survival strategies in the presence of antimicrobials Igor V. Chebotar’, Marina A. Emelyanova, Julia A. Bocharova, Nikolay A. Mayansky, Elena E. Kopantseva, Vladimir M. Mikhailovich Microbial Pathogenesis.2021; 155: 104901. CrossRef
Role of Toxin-Antitoxin-Regulated Persister Population and Indole in Bacterial Heat Tolerance Yoshimitsu Masuda, Erika Sakamoto, Ken-ichi Honjoh, Takahisa Miyamoto, Danilo Ercolini Applied and Environmental Microbiology.2020;[Epub] CrossRef
Bioconversion of Biologically Active Indole Derivatives with Indole-3-Acetic Acid-Degrading Enzymes from Caballeronia glathei DSM50014 Mikas Sadauskas, Roberta Statkevičiūtė, Justas Vaitekūnas, Rolandas Meškys Biomolecules.2020; 10(4): 663. CrossRef
Antibiofilm and Antivirulence Properties of Indoles Against Serratia marcescens Sivasamy Sethupathy, Ezhaveni Sathiyamoorthi, Yong-Guy Kim, Jin-Hyung Lee, Jintae Lee Frontiers in Microbiology.2020;[Epub] CrossRef
Local and Universal Action: The Paradoxes of Indole Signalling in Bacteria Ashraf Zarkan, Junyan Liu, Marta Matuszewska, Hannah Gaimster, David K. Summers Trends in Microbiology.2020; 28(7): 566. CrossRef
Experimental investigation into indole production using passaging of E. coli and B. subtilis along with unstructured modeling and parameter estimation using dynamic optimization: An integrated framework Ranjana Singh, Surbhi Sharma, Venkatesh V. Kareenhalli, Lopamudra Giri, Kishalay Mitra Biochemical Engineering Journal.2020; 163: 107743. CrossRef
Genome Insights of the Plant-Growth Promoting Bacterium Cronobacter muytjensii JZ38 With Volatile-Mediated Antagonistic Activity Against Phytophthora infestans Abdul Aziz Eida, Salim Bougouffa, Floriane L’Haridon, Intikhab Alam, Laure Weisskopf, Vladimir B. Bajic, Maged M. Saad, Heribert Hirt Frontiers in Microbiology.2020;[Epub] CrossRef
Rich Repertoire of Quorum Sensing Protein Coding Sequences in CPR and DPANN Associated with Interspecies and Interkingdom Communication Charles Bernard, Romain Lannes, Yanyan Li, Éric Bapteste, Philippe Lopez, Robert G. Beiko mSystems.2020;[Epub] CrossRef
Modified QuEChERS extraction for the analysis of young-of-year smallmouth bass using GC × GC-TOFMS Paige Teehan, Megan K. Schall, Vicki S. Blazer, Beate Gruber, Frank L. Dorman Analytical Methods.2020; 12(29): 3697. CrossRef
Indole Pulse Signalling Regulates the Cytoplasmic pH of E. coli in a Memory-Like Manner Ashraf Zarkan, Santiago Caño-Muñiz, Jinbo Zhu, Kareem Al Nahas, Jehangir Cama, Ulrich F. Keyser, David K. Summers Scientific Reports.2019;[Epub] CrossRef
Indole Inhibits ToxR Regulon Expression in
Vibrio cholerae
Mondraya F. Howard, X. Renee Bina, James E. Bina, Shelley M. Payne Infection and Immunity.2019;[Epub] CrossRef
Surface-enhanced Raman scattering (SERS) imaging of bioactive metabolites in mixed bacterial populations Sarah De Marchi, Gustavo Bodelón, Lorena Vázquez-Iglesias, Luis M. Liz-Marzán, Jorge Pérez-Juste, Isabel Pastoriza-Santos Applied Materials Today.2019; 14: 207. CrossRef
Differential Susceptibility of Catheter Biomaterials to Biofilm-Associated Infections and Their Remedy by Drug-Encapsulated Eudragit RL100 Nanoparticles Vivek Kumar Pandey, Kumar Rohit Srivastava, Gufran Ajmal, Vijay Kumar Thakur, Vijai Kumar Gupta, Siddh Nath Upadhyay, Pradeep Kumar Mishra International Journal of Molecular Sciences.2019; 20(20): 5110. CrossRef
Profiles of volatile indole emitted by Escherichia coli based on CDI-MS Qiaoshi Zhong, Feng Cheng, Juchao Liang, Xiaozhong Wang, Yanhui Chen, Xueyao Fang, Longhua Hu, Yaping Hang Scientific Reports.2019;[Epub] CrossRef
Can Herbivore-Induced Volatiles Protect Plants by Increasing the Herbivores’ Susceptibility to Natural Pathogens? Laila Gasmi, María Martínez-Solís, Ada Frattini, Meng Ye, María Carmen Collado, Ted C. J. Turlings, Matthias Erb, Salvador Herrero, Alfons J. M. Stams Applied and Environmental Microbiology.2019;[Epub] CrossRef
Indigoid dyes by group E monooxygenases: mechanism and biocatalysis Thomas Heine, Carolin Großmann, Sarah Hofmann, Dirk Tischler Biological Chemistry.2019; 400(7): 939. CrossRef
Efficient colonization of the endophytes Herbaspirillum huttiense RCA24 and Enterobacter cloacae RCA25 influences the physiological parameters of Oryza sativa L. cv. Baldo rice Anna Andreozzi, Pilar Prieto, Jesús Mercado‐Blanco, Stefano Monaco, Elisa Zampieri, Silvia Romano, Gianpiero Valè, Roberto Defez, Carmen Bianco Environmental Microbiology.2019; 21(9): 3489. CrossRef
Reprioritization of biofilm metabolism is associated with nutrient adaptation and long-term survival of Haemophilus influenzae Alistair Harrison, Rachael L. Hardison, Rachel M. Wallace, James Fitch, Derek R. Heimlich, Meghan O’ Bryan, Laura Dubois, Lisa St. John-Williams, Robert P. Sebra, Peter White, M. Arthur Moseley, J. Will Thompson, Sheryl S. Justice, Kevin M. Mason npj Biofilms and Microbiomes.2019;[Epub] CrossRef
Necrobiome framework for bridging decomposition ecology of autotrophically and heterotrophically derived organic matter M. Eric Benbow, Philip S. Barton, Michael D. Ulyshen, James C. Beasley, Travis L. DeVault, Michael S. Strickland, Jeffery K. Tomberlin, Heather R. Jordan, Jennifer L. Pechal Ecological Monographs.2019;[Epub] CrossRef
Biodegradation characteristics and genomic functional analysis of indole‐degrading bacterial strain Acinetobacter sp. JW Xuwang Zhang, Jiawei Jing, Lizhi Zhang, Zhaojian Song, Hao Zhou, Minghuo Wu, Yuanyuan Qu, Lifen Liu Journal of Chemical Technology & Biotechnology.2019; 94(4): 1114. CrossRef
Synthesis of 1H-3-{4-[(3-Dimethylaminopropyl)aminomethyl]phenyl}-2-phenylindole and Evaluation of Its Antiprotozoal Activity Jean Guillon, Clotilde Boudot, Anita Cohen, Solène Savrimoutou, Sandra Rubio, Vittoria Milano, Mathieu Marchivie, Nadine Azas, Catherine Mullié, Pascal Sonnet, Bertrand Courtioux Molbank.2019; 2019(2): M1060. CrossRef
Enantioselective α-Aminophosphonate Functionalization of Indole Ring through an Organocatalyzed Friedel–Crafts Reaction Aitor Maestro, Edorta Martinez de Marigorta, Francisco Palacios, Javier Vicario The Journal of Organic Chemistry.2019; 84(2): 1094. CrossRef
Pantoea agglomeransYS19 poly(A) polymerase I gene possesses the indole-sensing sequence in the promoter region Jing Zheng, Qi Liu, Yifan Xia, Lijuan Bai, Yongjun Feng FEMS Microbiology Letters.2019;[Epub] CrossRef
Phylogenetically diverse endophytic bacteria from desert plants induce transcriptional changes of tissue-specific ion transporters and salinity stress in Arabidopsis thaliana Abdul Aziz Eida, Hanin S. Alzubaidy, Axel de Zélicourt, Lukáš Synek, Wiam Alsharif, Feras F. Lafi, Heribert Hirt, Maged M. Saad Plant Science.2019; 280: 228. CrossRef
The Two-Component System ZraPSR Is a Novel ESR that Contributes to Intrinsic Antibiotic Tolerance in Escherichia coli Kévin Rome, Céline Borde, Raleb Taher, Julien Cayron, Christian Lesterlin, Erwan Gueguen, Eve De Rosny, Agnès Rodrigue Journal of Molecular Biology.2018; 430(24): 4971. CrossRef
N-dodecanoyl-homoserine lactone influences the levels of thiol and proteins related to oxidation-reduction process in Salmonella Felipe Alves de Almeida, Deisy Guimarães Carneiro, Tiago Antônio de Oliveira Mendes, Edvaldo Barros, Uelinton Manoel Pinto, Leandro Licursi de Oliveira, Maria Cristina Dantas Vanetti, Luis Caetano Martha Antunes PLOS ONE.2018; 13(10): e0204673. CrossRef
Regulation of Escherichia coli Biofilm Formation (Review) J. A. Markova, E. V. Anganova, A. L. Turskaya, V. A. Bybin, E. D. Savilov Applied Biochemistry and Microbiology.2018; 54(1): 1. CrossRef
Formate Promotes
Shigella
Intercellular Spread and Virulence Gene Expression
Benjamin J. Koestler, Carolyn R. Fisher, Shelley M. Payne, Bonnie Bassler mBio.2018;[Epub] CrossRef
Gut microbiota and transportation stress response affected by tryptophan supplementation in broiler chickens Alhassan U. Bello, Zulkifli Idrus, Goh Yong Meng, Elmutaz Atta Awad, Abdoreza Soleimani Farjam Italian Journal of Animal Science.2018; 17(1): 107. CrossRef
Indole-Induced Activities of β-Lactamase and Efflux Pump Confer Ampicillin Resistance in Pseudomonas putida KT2440 Jisun Kim, Bora Shin, Chulwoo Park, Woojun Park Frontiers in Microbiology.2017;[Epub] CrossRef
Electrochemical reverse engineering: A systems-level tool to probe the redox-based molecular communication of biology Jinyang Li, Yi Liu, Eunkyoung Kim, John C. March, William E. Bentley, Gregory F. Payne Free Radical Biology and Medicine.2017; 105: 110. CrossRef
Assessments of iodoindoles and abamectin as inducers of methuosis in pinewood nematode, Bursaphelenchus xylophilus
Satish Kumar Rajasekharan, Jin-Hyung Lee, Vinothkannan Ravichandran, Jintae Lee Scientific Reports.2017;[Epub] CrossRef
Expanding the Chemical Repertoire of the Endophyte Streptomyces albospinus RLe7 Reveals Amphotericin B as an Inducer of a Fungal Phenotype Fernanda Oliveira Chagas, Andrés Mauricio Caraballo-Rodríguez, Pieter C. Dorrestein, Mônica Tallarico Pupo Journal of Natural Products.2017; 80(5): 1302. CrossRef
Lateral gene transfer of p‐cresol‐ and indole‐producing enzymes from environmental bacteria to Mastigamoeba balamuthi Eva Nývltová, Robert Šut'ák, Vojtěch Žárský, Karel Harant, Ivan Hrdý, Jan Tachezy Environmental Microbiology.2017; 19(3): 1091. CrossRef
Indole at low concentration helps exponentially growing Escherichia coli survive at high temperature Junyan Liu, David Summers, Finbarr Hayes PLOS ONE.2017; 12(12): e0188853. CrossRef
Antibiofilm agents: A new perspective for antimicrobial strategy Xi-Hui Li, Joon-Hee Lee Journal of Microbiology.2017; 55(10): 753. CrossRef
Metabonomics of ageing – Towards understanding metabolism of a long and healthy life Francois-Pierre J. Martin, Ivan Montoliu, Martin Kussmann Mechanisms of Ageing and Development.2017; 165: 171. CrossRef
An indole‐deficient Escherichia coli strain improves screening of cytochromes P450 for biotechnological applications Simone Brixius‐Anderko, Frank Hannemann, Michael Ringle, Yogan Khatri, Rita Bernhardt Biotechnology and Applied Biochemistry.2017; 64(3): 315. CrossRef
Disarming the enemy: targeting bacterial toxins with small molecules Daniel Walker, Alejandro Huerta-Uribe, Andrew J. Roe Emerging Topics in Life Sciences.2017; 1(1): 31. CrossRef
Mechanisms of bacterial persistence during stress and antibiotic exposure Alexander Harms, Etienne Maisonneuve, Kenn Gerdes Science.2016;[Epub] CrossRef
Cascade Reactions of Nitrones and Allenes for the Synthesis of Indole Derivatives Laura L. Anderson, Michelle A. Kroc, Tyler W. Reidl, Jongwoo Son The Journal of Organic Chemistry.2016; 81(20): 9521. CrossRef
Intrinsic relative nucleophilicity of indoles Eduardo Chamorro, Mario Duque-Noreña, Mar Ríos-Gutiérrez, Luis R. Domingo, Patricia Pérez Theoretical Chemistry Accounts.2016;[Epub] CrossRef
Gut Bacteria and Hydrogen Sulfide: The New Old Players in Circulatory System Homeostasis Lenka Tomasova, Piotr Konopelski, Marcin Ufnal Molecules.2016; 21(11): 1558. CrossRef
Products of gut-microbial tryptophan metabolism inhibit the steroid hormone-synthesizing cytochrome P450 11A1 A. Mosa, A. Gerber, J. Neunzig, Rita Bernhardt Endocrine.2016; 53(2): 610. CrossRef
Biofilm dispersion in Pseudomonas aeruginosa Soo-Kyoung Kim, Joon-Hee Lee Journal of Microbiology.2016; 54(2): 71. CrossRef
Xenobiotic Receptor-Mediated Regulation of Intestinal Barrier Function and Innate Immunity Harmit S. Ranhotra, Kyle L. Flannigan, Martina Brave, Subhajit Mukherjee, Dana J. Lukin, Simon A. Hirota, Sridhar Mani Nuclear Receptor Research.2016;[Epub] CrossRef
Is Fluorescence Valid to Monitor Removal of Protein Bound Uremic Solutes in Dialysis? Jürgen Arund, Merike Luman, Fredrik Uhlin, Risto Tanner, Ivo Fridolin, Sabato D'Auria PLOS ONE.2016; 11(5): e0156541. CrossRef