MSK
Search
- Page Path
- HOME > Search
Research Support, Non-U.S. Gov't
- Phospholipase A2 Inhibitors in Bacterial Culture Broth Enhance Pathogenicity of a Fungus Nomuraea rileyi
- Jung-A Park , Yonggyun Kim
- J. Microbiol. 2012;50(4):644-651. Published online July 21, 2012
- DOI: https://doi.org/10.1007/s12275-012-2108-3
- 58 View
- 0 Download
- 12 Crossref
-
Abstract
- An entomopathogenic fungus, Nomuraea rileyi, was isolated and its identity was confirmed by its internal transcribed spacer DNA sequence. The isolated N. rileyi exhibited a specific pathogenicity to lepidopteran species. This study was focused on enhancing the fungal pathogenicity by using immunosuppressive agents. In response to infection of N. rileyi, Spodoptera exigua larvae significantly induced catalytic activity of phospholipase A2 (PLA2) in three immune-associated tissues, namely hemocytes, fat body, and hemolymph plasma. Furthermore, the infected S. exigua larvae induced transcription of several antimicrobial peptide (AMP) genes. Two entomopathogenic bacteria, Xenorhabdus nematophila (Xn) and Photorhabdus temperata subsp. temperata (Ptt), possessed specific PLA2-inhibitory activities and their culture broths significantly inhibited the enzyme activities in hemocytes, fat body, and plasma of S. exigua. In addition, the bacterial metabolites inhibited transcription of AMP genes in S. exigua that would normally respond to the immune challenge by N. rileyi. The immunosuppressive effect of Xn or Ptt bacterial broth resulted in significant enhancement of the fungal pathogenicity against late instar larvae of S. exigua and Plutella xylostella. The effect of such a mixture was confirmed by field assay against two lepidopteran species. These results suggest that the bacterial and fungal mixture can be applied to develop a novel biopesticide to control lepidopteran species.
-
Citations
Citations to this article as recorded by
- The role of BmsPLA2‐4 in tissue defense against pathogens in silkworm, Bombyx mori
Jiangtao Xiong, Zunmei Hu, Gemin Wang, Chunyang Wang, Ping Chen
Insect Science.2025;[Epub] CrossRef - The role and mechanism of BmsPLA2-1-1 in the IMD pathway in silkworm, Bomybx mori
Wei He, Tian Li, Benhua Xiong, Lunfu Shen, Ping Chen
International Journal of Biological Macromolecules.2024; 283: 137297. CrossRef - A secreted phospholipase A2 (BmsPLA2) regulates melanization of immunity through BmDDC in the silkworm Bombyx mori
Tian Li, Gemin Wang, Wei He, Guiqin Li, Chunyang Wang, Jiamei Zhao, Pan Chen, Meiwei Guo, Ping Chen
Insect Science.2023; 30(6): 1579. CrossRef - The Entomopathogenic Nematodes H. bacteriophora and S. carpocapsae Inhibit the Activation of proPO System of the Nipa Palm Hispid Octodonta nipae (Coleoptera: Chrysomelidae)
Nafiu Sanda, Bofeng Hou, Youming Hou
Life.2022; 12(7): 1019. CrossRef - Toll signal pathway activating eicosanoid biosynthesis shares its conserved upstream recognition components in a lepidopteran Spodoptera exigua upon infection by Metarhizium rileyi, an entomopathogenic fungus
Miltan Chandra Roy, Yonggyun Kim
Journal of Invertebrate Pathology.2022; 188: 107707. CrossRef - Thromboxane Mobilizes Insect Blood Cells to Infection Foci
Miltan Chandra Roy, Kiwoong Nam, Jaesu Kim, David Stanley, Yonggyun Kim
Frontiers in Immunology.2021;[Epub] CrossRef - Repat33 Acts as a Downstream Component of Eicosanoid Signaling Pathway Mediating Immune Responses of Spodoptera exigua, a Lepidopteran Insect
Md Tafim Hossain Hrithik, Mohammad Vatanparast, Shabbir Ahmed, Yonggyun Kim
Insects.2021; 12(5): 449. CrossRef - A prophylactic role of a secretory PLA2 of Spodoptera exigua against entomopathogens
Mohammad Vatanparast, Shabbir Ahmed, Seyedeh Minoo Sajjadian, Yonggyun Kim
Developmental & Comparative Immunology.2019; 95: 108. CrossRef - Role of Endosymbionts in Insect–Parasitic Nematode Interactions
Ioannis Eleftherianos, Shruti Yadav, Eric Kenney, Dustin Cooper, Yaprak Ozakman, Jelena Patrnogic
Trends in Parasitology.2018; 34(5): 430. CrossRef - Brevibacillus laterosporus pathogenesis and local immune response regulation in the house fly midgut
Maria Elena Mura, Luca Ruiu
Journal of Invertebrate Pathology.2017; 145: 55. CrossRef - Metarhizium(Nomuraea)rileyias biological control agent
Edegar Fronza, Alexandre Specht, Horacio Heinzen, Neiva Monteiro de Barros
Biocontrol Science and Technology.2017; 27(11): 1243. CrossRef - Characteristics and Virulence Assay of Entomopathogenic Fungus Nomuraea rileyi for the Microbial Control of Spodoptera exigua (Lepidoptera: Noctuidae)
Won Woo Lee, Tae Young Shin, Seung Hyun Ko, Jae Bang Choi, Sung Min Bae, Soo Dong Woo
The Korean Journal of Microbiology.2012; 48(4): 284. CrossRef
- The role of BmsPLA2‐4 in tissue defense against pathogens in silkworm, Bombyx mori
First
Prev
TOP
