Journal of Microbiology

Journal Article

Predicting quorum sensing peptides using stacked generalization ensemble with gradient boosting based feature selection: Muthusaravanan Sivaramakrishnan , Rahul Suresh , Kannapiran Ponraj; J. Microbiol. 2022;60(7):756-765. Published online June 22, 2022; DOI: https://doi.org/10.1007/s12275-022-2044-9

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Bacteria exist in natural environments for most of their life as complex, heterogeneous, and multicellular aggregates. Under these circumstances, critical cell functions are controlled by several signaling molecules known as quorum sensing (QS) molecules. In Gram-positive bacteria, peptides are deployed as QS molecules. The development of antibodies against such QS molecules has been identified as a promising therapeutic intervention for bacterial control. Hence, the identification of QS peptides has received considerable attention. Availability of a fast and reliable predictive model to effectively identify QS peptides can help the existing high throughput experiments. In this study, a stacked generalization ensemble model with Gradient Boosting Machine (GBM)-based feature selection, namely EnsembleQS was developed to predict QS peptides with high accuracy. On selected GBM features (791D), the EnsembleQS outperformed finely tuned baseline classifiers and demonstrated robust performance, indicating the superiority of the model. The accuracy of EnsembleQS is 4% higher than those resulting from ensemble model on hybrid dataset. When evaluating an independent data set of 40 QS peptides, the EnsembleQS model showed an accuracy of 93.4% with Matthew’s Correlation Coefficient (MCC) and area under the ROC curve (AUC) values 􀁇􀁇of 0.91 and 0.951, respectively. These
results
suggest that EnsembleQS will be a useful computational framework for predicting QS peptides and will efficiently support proteomics research. The source code and all datasets used in this study are publicly available at https:// github.com/proteinexplorers/EnsembleQS.

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IQSPred-PLM: An Interpretable Quorum Sensing Peptides Prediction Model Based on Protein Language Model
Yusen Su, Qingyang Guo, Taigang Liu
Interdisciplinary Sciences: Computational Life Sciences.2025;[Epub] CrossRef
Kernelized Fuzzy System for Predicting Therapeutic Peptides via Deep Stacked Encoder
Xiaoyi Guo, Yijie Ding, Quan Zou
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Rahul Suresh, Hardik Bishnoi, Artem V. Kuklin, Atharva Parikh, Maxim Molokeev, R. Harinarayanan, Sarvesh Gharat, P. Hiba
Frontiers in Physics.2024;[Epub] CrossRef
DeepQSP: Identification of Quorum Sensing Peptides Through Neural Network Model
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PSRQSP: An effective approach for the interpretable prediction of quorum sensing peptide using propensity score representation learning
Phasit Charoenkwan, Pramote Chumnanpuen, Nalini Schaduangrat, Changmin Oh, Balachandran Manavalan, Watshara Shoombuatong
Computers in Biology and Medicine.2023; 158: 106784. CrossRef

Research Support, Non-U.S. Gov'ts

Providencia Isolates Carrying blaPER-1 and blaVIM-2 Genes: Biofilm-Forming Capacity and Biofilm Inhibitory Concentrations for Carbapenem Antibiotics: Jungmin Kim , Shukho Kim , Hee Woo Lee , Sung Min Kim , Sung Yong Seol; J. Microbiol. 2011;49(3):512-515. Published online June 30, 2011; DOI: https://doi.org/10.1007/s12275-011-1221-z

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Abstract PDF: Multidrug-resistant clinical isolates of Providencia carrying blaPER-1 and blaVIM-2 were evaluated for the abilities to form biofilm and high biofilm forming capacity was demonstrated in them. Minimum biofilm inhibitory concentrations (MBICs), minimum biofilm eradication concentrations (MBECs), and minimum inhibitory concentrations (MICs) for imipenem and meropenem were also determined. In all tested strains, the MBICs were higher than the MICs for both drugs. Interestingly, the MBICs and the MBEC50 for meropenem were lower than those for imipenem in the isolates producing high amounts of biofilm, suggesting that meropenem is superior to imipenem in the growth inhibition and eradication of biofilm forming Providencia strains.

Acinetobacter baumannii Biofilms: Variations Among Strains and Correlations with Other Cell Properties: Christin N. McQueary , Luis A. Actis; J. Microbiol. 2011;49(2):243-250. Published online May 3, 2011; DOI: https://doi.org/10.1007/s12275-011-0343-7

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Abstract PDF: Acinetobacter baumannii is an opportunistic pathogen that causes serious infections in humans by colonizing and persisting on surfaces normally found in hospital settings. The capacity of this pathogen to persist in these settings could be due to its ability to form biofilms on inanimate surfaces. This report shows that although the ATCC 19606T type strain and 8 different clinical isolates form biofilms, there are significant variations in the cell density and microscopic structures of these cell aggregates, with 3 of the isolates forming pellicles floating on the surface of stagnant broth cultures. PCR indicated that, like ATCC 19606T, all 8 clinical isolates harbor all the genetic components of the CsuA/BABCDE chaperone-usher pili assembly system, which is needed for biofilm formation on plastic. Pili detection in cells of all strains examined supports the presence and function of a pilus assembly system. However, only one of them produced the putative ATCC 19606T CsuA/B pilin subunit protein. Hydrophobicity tests and motility assays also showed significant variations among all tested strains and did not result in direct correlations between the biofilm phenotype and cell properties that could affect biofilm formation on abiotic surfaces. This lack of correlation among these 3 phenotypes may reflect some of the variations already reported with this pathogen, which may pose a challenge in the treatment of the infections this pathogen causes in humans using biofilm formation on abiotic surfaces as a target.

Inhibitory Effect of Lactobacillus reuteri on Periodontopathic and Cariogenic Bacteria: Mi-Sun Kang , Jong-Suk Oh , Hyun-Chul Lee , Hoi-Soon Lim , Seok-Woo Lee , Kyu-Ho Yang , Nam-Ki Choi , Seon-Mi Kim; J. Microbiol. 2011;49(2):193-199. Published online May 3, 2011; DOI: https://doi.org/10.1007/s12275-011-0252-9

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Abstract PDF

The interaction between Lactobacillus reuteri, a probiotic bacterium, and oral pathogenic bacteria have not been studied adequately. This study examined the effects of L. reuteri on the proliferation of periodontopathic bacteria including Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Porphyromonas gingivalis, and Tannerella forsythia, and on the formation of Streptococcus mutans biofilms. Human-derived L. reuteri strains (KCTC 3594 and KCTC 3678) and rat-derived L. reuteri KCTC 3679 were used. All strains exhibited significant inhibitory effects on the growth of periodontopathic bacteria and the formation of S. mutans biofilms. These antibacterial activities of L. reuteri were attributed to the production of organic acids, hydrogen peroxide, and a bacteriocin-like compound. Reuterin, an antimicrobial factor, was produced only by L. reuteri KCTC 3594. In addition, L. reuteri inhibited the production of methyl mercaptan by F. nucleatum and P. gingivalis. Overall, these results suggest that L. reuteri may be useful as a probiotic agent for improving oral health.

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Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study
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Journal of Korean Society of Dental Hygiene.2025; 25(2): 101. CrossRef
Effect of Lactobacillus reuteri probiotic on gingival index and Interleukin-1β levels of children with thalassemia experiencing gingivitis
Indira Betari Sumendap, Heriandi Sutadi, Eva Fauziah, Pustika Amalia Wahidiyat
Journal of Indian Society of Pedodontics and Preventive Dentistry.2025; 43(2): 231. CrossRef
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Charlene Enhui Goh, Rohan Williams, Nitasha Gupta, Francis Ho, Intekhab Islam, Clement Wei Ming Lai, Kai Soo Tan, Catherine Hsu Ling Hong
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Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis
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Probiotics-embedded polymer films for oral health: Development, characterization, and therapeutic potential
Charlotte Eckermann, Christof Johannes Klein, Florian Schäfer, Marc Thiel, Agnes-Valencia Weiss, Christian Motz, Karen Lienkamp, Matthias Hannig, Marc Schneider
Colloids and Surfaces B: Biointerfaces.2025; 255: 114886. CrossRef
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Su-yeong Choi, Jang-Sub Lee, Suk-Jin Ha
KSBB Journal.2025; 40(2): 126. CrossRef
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Mao-Cheng Sun, Yu-Xin Chen, Xiu-Juan Fan, Ying-Di Wang, Tiehua Zhang, Changhui Zhao
Food Bioscience.2025; 63: 105744. CrossRef
Limosilactobacillus reuteri and Its Probiotic Potential against Cariogenic Bacteria
Brianda Karina Félix-Sicairos, Rita Elizabeth Martinez-Martinez, Saray Aranda-Romo, Roberto Gonzalez-Amaro, Mariana Salgado-Bustamante, Norma Verónica Zavala-Alonso, Ángel Gabriel Alpuche-Solís
Microbiology Research.2024; 15(3): 1178. CrossRef
Lactobacillus fermentum attenuates the alveolar bone loss in ligature‐induced periodontitis in mice
Yuni Lee, Bo Hyun Jung, Ki‐Yeon Yoo, Hye Ji Lim, Kum‐Joo Shin, Jae‐Kwan Lee
Oral Diseases.2024; 30(5): 3328. CrossRef
The Effects of Electrolytic Technology Toothbrush Application on the Clinical Parameters and Bacteria Associated with Periodontal Disease in Dogs
Nemanja Zdravković, Nemanja Stanisavljević, Milka Malešević, Goran Vukotić, Tatjana Stevanović, Ivan Bošnjak, Milan Ninković
Animals.2024; 14(21): 3067. CrossRef
Ribosomally synthesized bacteriocins of lactic acid bacteria: Simplicity yet having wide potentials – A review
Ghoson Mosbah Daba, Waill Ahmed Elkhateeb
International Journal of Biological Macromolecules.2024; 256: 128325. CrossRef
Bacterial protein acetylation: mechanisms, functions, and methods for study
Jocelin Rizo, Sergio Encarnación-Guevara
Frontiers in Cellular and Infection Microbiology.2024;[Epub] CrossRef
Preventive effect of Lacticaseibacillus paracasei LMT18-32 on Porphyromonas gingivalis induced periodontitis
Woo Jin Choi, Seung Kee Cho, Hye Jin Dong, Tai Hoon Kim, Jaejoon Soon, Hyo Jin Lee, Kwang Ho Yoon, Seongsung Kwak, Jiae Yun
Food Science and Biotechnology.2024; 33(9): 2161. CrossRef
The Impact of Lactobacillus reuteri on Oral and Systemic Health: A Comprehensive Review of Recent Research
Zihui Liu, Qing Cao, Wenqing Wang, Bowen Wang, Yilun Yang, Cory J. Xian, Tiejun Li, Yuankun Zhai
Microorganisms.2024; 13(1): 45. CrossRef
Corrected and Republished from: “Understanding Lactobacillus paracasei and Streptococcus oralis Biofilm Interactions through Agent-Based Modeling”
Linda Archambault, Sherli Koshy-Chenthittayil, Angela Thompson, Anna Dongari-Bagtzoglou, Reinhard Laubenbacher, Pedro Mendes, Craig D. Ellermeier
mSphere.2023;[Epub] CrossRef
Overview of oral health status and associated risk factors in maritime settings: An updated systematic review
Tuan P. A. Nguyen, Sanju Gautam, Sweta Mahato, Olaf Chresten Jensen, Arezoo Haghighian-Roudsari, Fereshteh Baygi, Tanay Chaubal
PLOS ONE.2023; 18(10): e0293118. CrossRef
In Vitro Characterization of Limosilactobacillus reuteri Lac Ib01 (OL468126.1) Isolated from Traditional Sheep Dry Sausage and Evaluation of the Activity of Arthrospira platensis or Phycocyanin on Its Growth-Promoting Ability
Ibtissem Chakroun, Najla Haddaji, Kais Fedhila, Makaoui Maatallah, Ridha Mzoughi, Yassine Chaabouni, Youssef Krichen, Amina Bakhrouf
Fermentation.2023; 9(3): 248. CrossRef
Microencapsulation of Probiotic Streptococcus salivarius LAB813
Priyadarshani Choudhary, Heinz-Bernhard Kraatz, Céline M. Lévesque, Siew-Ging Gong
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Formulation of chewing gum containing Lactobacillus brevis NB10
Nhu Thi Quynh Thai, Huy Nguyen Manh, Thanh Van Tran, Anh Tuan Le
MedPharmRes.2023; 7(2): 13. CrossRef
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P. R. Vanitha, Rakesh Somashekaraiah, S. Divyashree, Indranil Pan, M. Y. Sreenivasa
Frontiers in Microbiology.2023;[Epub] CrossRef
In Vitro Preventive Effect and Mechanism of Action of Weissella cibaria CMU against Streptococcus mutans Biofilm Formation and Periodontal Pathogens
Mi-Sun Kang, Geun-Yeong Park, A-Reum Lee
Microorganisms.2023; 11(4): 962. CrossRef
Screening of heat-killed lactic acid bacteria based on inhibitory activity against oral bacteria and effects of oral administration of heat-killed Ligilactobacillus salivarius CP3365 on periodontal health in healthy pa
Shinji Sakata, Yukiko Sakamaki, Masahiro Yuki, Tsutomu Sugaya, Tatsuhiko Hirota
Journal of Oral Microbiology.2023;[Epub] CrossRef
Growth Conditions Influence Lactobacillus Cell-Free Supernatant Impact on Viability, Biofilm Formation, and Co-Aggregation of the Oral Periodontopathogens Fusobacterium nucleatum and Porphyromonas gingivalis
Paola Zanetta, Diletta Francesca Squarzanti, Alessia di Coste, Angela Amoruso, Marco Pane, Barbara Azzimonti
Biomedicines.2023; 11(3): 859. CrossRef
Mecanismos de acción de los probióticos en la inhibición de microorganismos cariogénicos
Yari Lizbeth Pablo López, Rafael Torres-Rosas, Liliana Argueta-Figueroa
Revista Médica Clínica Las Condes.2023; 34(3): 216. CrossRef
Nutritional factors influencing microbiota-mediated colonization resistance of the oral cavity: A literature review
Nuraly S. Akimbekov, Ilya Digel, Adil Y. Yerezhepov, Raiymbek S. Shardarbek, Xia Wu, Jian Zha
Frontiers in Nutrition.2022;[Epub] CrossRef
Leuconostoc mesenteroides LVBH107 Antibacterial Activity against Porphyromonas gingivalis and Anti-Inflammatory Activity against P. gingivalis Lipopolysaccharide-Stimulated RAW 264.7 Cells
Chang Luan, Jiaqing Yan, Ning Jiang, Chuang Zhang, Xu Geng, Zhengqiang Li, Chen Li
Nutrients.2022; 14(13): 2584. CrossRef
Lactobacillus reuteri AN417 cell-free culture supernatant as a novel antibacterial agent targeting oral pathogenic bacteria
Kyung Mi Yang, Ji-Sun Kim, Hye-Sung Kim, Young-Youn Kim, Jeong-Kyu Oh, Hye-Won Jung, Doo-Sang Park, Kwang-Hak Bae
Scientific Reports.2021;[Epub] CrossRef
Effectiveness of probiotic lozenges and Chlorhexidine mouthwash on plaque index, salivary pH, and Streptococcus mutans count among school children in Makkah, Saudi Arabia
Sara Matuq Badri, Emtenan Hesham Felemban, Ghaida Kamel Alnajjar, Fadwa Monawar Alotaibi, Shorooq Talin Aljahdali, Yahia Ahmed Maher, Adel Fathi
The Saudi Dental Journal.2021; 33(7): 635. CrossRef
Isolation, Characterization and Biosafety Evaluation of Lactobacillus Fermentum OK with Potential Oral Probiotic Properties
Soyon Mann, Myeong Soo Park, Tony V. Johnston, Geun Eog Ji, Keum Taek Hwang, Seockmo Ku
Probiotics and Antimicrobial Proteins.2021; 13(5): 1363. CrossRef
An approach to extend the shelf life of ribbonfish fillet using lactic acid bacteria cell-free culture supernatant
Du-Min Jo, Seul-Ki Park, Fazlurrahman Khan, Min-Gyun Kang, Jae-Hwa Lee, Young-Mog Kim
Food Control.2021; 123: 107731. CrossRef
Understanding Lactobacillus paracasei and Streptococcus oralis Biofilm Interactions through Agent-Based Modeling
Linda Archambault, Sherli Koshy-Chenthittayil, Angela Thompson, Anna Dongari-Bagtzoglou, Reinhard Laubenbacher, Pedro Mendes, Craig D. Ellermeier
mSphere.2021;[Epub] CrossRef
Antimicrobial and Antibiofilm Activities of Weissella cibaria against Pathogens of Upper Respiratory Tract Infections
Ji-Eun Yeu, Hyeon-Gyu Lee, Geun-Yeong Park, Jisun Lee, Mi-Sun Kang
Microorganisms.2021; 9(6): 1181. CrossRef
Effects of a derivative of reutericin 6 and gassericin A on the biofilm of Streptococcus mutans in vitro and caries prevention in vivo
Jingheng Liang, Dongsheng Liang, Yuee Liang, Jianing He, Shiya Zuo, Wanghong Zhao
Odontology.2021; 109(1): 53. CrossRef
Targeting biofilms in medical devices using probiotic cells: a systematic review
Fábio M. Carvalho, Rita Teixeira-Santos, Filipe J. M. Mergulhão, Luciana C. Gomes
AIMS Materials Science.2021; 8(4): 501. CrossRef
Acetylation of glucosyltransferases regulates Streptococcus mutans biofilm formation and virulence
Qizhao Ma, Yangyang Pan, Yang Chen, Shuxing Yu, Jun Huang, Yaqi Liu, Tao Gong, Jing Zou, Yuqing Li, Anders P. Hakansson
PLOS Pathogens.2021; 17(12): e1010134. CrossRef
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Yvonne Jockel-Schneider, Ulrich Schlagenhauf, Juliane Rehder
ZWR - Das Deutsche Zahnärzteblatt.2021; 130(05): 224. CrossRef
Orally Administered Probiotics Decrease Aggregatibacter actinomycetemcomitans but Not Other Periodontal Pathogenic Bacteria Counts in the Oral Cavity: A Systematic Review and Meta-Analysis
Thanyaporn Sang-Ngoen, László Márk Czumbel, Wuttapon Sadaeng, Alexandra Mikó, Dávid István Németh, Péter Mátrai, Péter Hegyi, Barbara Tóth, Dezső Csupor, István Kiss, Andrea Szabó, Gábor Gerber, Gábor Varga, Beáta Kerémi
Frontiers in Pharmacology.2021;[Epub] CrossRef
BiG-MAP: an Automated Pipeline To Profile Metabolic Gene Cluster Abundance and Expression in Microbiomes
Victória Pascal Andreu, Hannah E. Augustijn, Koen van den Berg, Justin J. J. van der Hooft, Michael A. Fischbach, Marnix H. Medema, Elizabeth Anne Shank
mSystems.2021;[Epub] CrossRef
Synergistic antibacterial effects of reuterin and catechin against Streptococcus mutans
Guofang Zhang, Ying Tan, Tianshu Yu, Sitong Wang, Libo Liu, Chun Li
LWT.2021; 139: 110527. CrossRef
Probiotic therapy for periodontal and peri-implant health – silver bullet or sham?
E. Ng, J.R.H. Tay, M.M.A. Ong, N. Bostanci, G.N. Belibasakis, C.J. Seneviratne
Beneficial Microbes.2021; 12(3): 215. CrossRef
Application of bacteriocins in food preservation and infectious disease treatment for humans and livestock: a review
Zhang Jin Ng, Mazni Abu Zarin, Chee Keong Lee, Joo Shun Tan
RSC Advances.2020; 10(64): 38937. CrossRef
Probiotic Effects on Multispecies Biofilm Composition, Architecture, and Caries Activity In Vitro
Zhihui Chen, Sebastian Schlafer, Gerd Göstemeyer, Falk Schwendicke
Microorganisms.2020; 8(9): 1272. CrossRef
Interaction between Lactobacillus reuteri and periodontopathogenic bacteria using in vitro and in vivo (G. mellonella) approaches
Thaís Aguiar Santos, Liliana Scorzoni, Raquel Correia, Juliana Campos Junqueira, Ana Lia Anbinder
Pathogens and Disease.2020;[Epub] CrossRef
Lactobacillus Plantarum 108 Inhibits Streptococcus mutans and Candida albicans Mixed-Species Biofilm Formation
Neha Srivastava, Kassapa Ellepola, Nityasri Venkiteswaran, Louis Yi Ann Chai, Tomoko Ohshima, Chaminda Jayampath Seneviratne
Antibiotics.2020; 9(8): 478. CrossRef
In vitro inhibitory effect of two commercial probiotics on chromogenic actinomycetes
E. Gobbi, M. A. De Francesco, G. Piccinelli, A. Caruso, E. Bardellini, A. Majorana
European Archives of Paediatric Dentistry.2020; 21(6): 673. CrossRef
Potential probiotic of Lactobacillus strains isolated from the intestinal tracts of pigs and feces of dogs with antibacterial activity against multidrug-resistant pathogenic bacteria
Chuen-Fu Lin, Meng-Yi Lin, Chao-Nan Lin, Ming-Tang Chiou, Jia-Wen Chen, Kai-Chieh Yang, Ming-Cheng Wu
Archives of Microbiology.2020; 202(7): 1849. CrossRef
Heat‐killed Lactobacillus reuteri and cell‐free culture supernatant have similar effects to viable probiotics during interaction with Porphyromonas gingivalis
Barbara M. C. Geraldo, Marianna N. Batalha, Noala V. M. Milhan, Rodnei D. Rossoni, Liliana Scorzoni, Ana Lia Anbinder
Journal of Periodontal Research.2020; 55(2): 215. CrossRef
Consumption of Lactobacillus reuteri‐containing lozenges improves periodontal health in navy sailors at sea: A randomized controlled trial
Ulrich Schlagenhauf, Juliane Rehder, Götz Gelbrich, Yvonne Jockel‐Schneider
Journal of Periodontology.2020; 91(10): 1328. CrossRef
Environment-Specific Probiotic Supernatants Modify the Metabolic Activity and Survival of Streptococcus mutans in vitro
Haiyue Yu, Petra Ganas, Falk Schwendicke
Frontiers in Microbiology.2020;[Epub] CrossRef
Isolation of Lactic acid bacteria showing antagonistic activity against Streptococcus mutans
Hanh Thi Hong Nguyen, Anh Tuan Le
MedPharmRes.2020; 4(2): 23. CrossRef
Rational design of peptides with enhanced antimicrobial and anti‐biofilm activities against cariogenic bacterium Streptococcus mutans
Dongsheng Liang, Huanying Li, Xiaohu Xu, Jingheng Liang, Xingzhu Dai, Wanghong Zhao
Chemical Biology & Drug Design.2019; 94(4): 1768. CrossRef
Characterization of Antibacterial Cell-Free Supernatant from Oral Care Probiotic Weissella cibaria, CMU
Hae-Soon Lim, Ji-Eun Yeu, Sang-Phil Hong, Mi-Sun Kang
Molecules.2018; 23(8): 1984. CrossRef
Dental biofilm: ecological interactions in health and disease
P. D. Marsh, Egija Zaura
Journal of Clinical Periodontology.2017;[Epub] CrossRef
Probiotic Lactobacillus reuteri has antifungal effects on oral Candida species in vitro
Mette Rose Jørgensen, Camilla Kragelund, Peter Østrup Jensen, Mette Kirstine Keller, Svante Twetman
Journal of Oral Microbiology.2017; 9(1): 1274582. CrossRef
Live and heat-killed Lactobacillus spp. interfere with Streptococcus mutans and Streptococcus oralis during biofilm development on titanium surface
E. Ciandrini, R. Campana, W. Baffone
Archives of Oral Biology.2017; 78: 48. CrossRef
Lactobacillus caviae sp. nov., an obligately heterofermentative bacterium isolated from the oral cavity of a guinea pig (Cavia aperea f. porcellus)
Jiri Killer, Radko Pechar, Pavel Švec, Hana Salmonová, Roman Švejstil, Martina Geigerová, Vojtěch Rada, Eva Vlková, Chahrazed Mekadim
International Journal of Systematic and Evolutionary Microbiology.2017; 67(8): 2903. CrossRef
Mechanisms and therapeutic effectiveness of lactobacilli
Alessandro Di Cerbo, Beniamino Palmieri, Maria Aponte, Julio Cesar Morales-Medina, Tommaso Iannitti
Journal of Clinical Pathology.2016; 69(3): 187. CrossRef
Clinical efficacy of probiotics as an adjunctive therapy to non‐surgical periodontal treatment of chronic periodontitis: a systematic review and meta‐analysis
Rodrigo Martin‐Cabezas, Jean‐Luc Davideau, Henri Tenenbaum, Olivier Huck
Journal of Clinical Periodontology.2016; 43(6): 520. CrossRef
Comparative Study on the Characteristics of Weissella cibaria CMU and Probiotic Strains for Oral Care
Hye-Jin Jang, Mi-Sun Kang, Sung-Hun Yi, Ji-Young Hong, Sang-Pil Hong
Molecules.2016; 21(12): 1752. CrossRef
Antimicrobial Effect of Lactobacillus reuteri on Cariogenic Bacteria Streptococcus gordonii, Streptococcus mutans, and Periodontal Diseases Actinomyces naeslundii and Tannerella forsythia
Magda Lorena Baca-Castañón, Myriam Angélica De la Garza-Ramos, Andrea Guadalupe Alcázar-Pizaña, Yohann Grondin, Anahí Coronado-Mendoza, Rosa Isela Sánchez-Najera, Eloy Cárdenas-Estrada, Carlos Eduardo Medina-De la Garza, Erandi Escamilla-García
Probiotics and Antimicrobial Proteins.2015; 7(1): 1. CrossRef
A study on β-defensin-2 and histatin-5 as a diagnostic marker of early childhood caries progression
Anna Jurczak, Dorota Kościelniak, Monika Papież, Palina Vyhouskaya, Wirginia Krzyściak
Biological Research.2015;[Epub] CrossRef
Lactobacillus brevis CD2 inhibits Prevotella melaninogenica biofilm
C Vuotto, F Barbanti, P Mastrantonio, G Donelli
Oral Diseases.2014; 20(7): 668. CrossRef
The virulence of Streptococcus mutans and the ability to form biofilms
W. Krzyściak, A. Jurczak, D. Kościelniak, B. Bystrowska, A. Skalniak
European Journal of Clinical Microbiology & Infectious Diseases.2014; 33(4): 499. CrossRef
Effect of Oral Administration Involving a Probiotic Strain of Lactobacillus reuteri on Pro-Inflammatory Cytokine Response in Patients with Chronic Periodontitis
Anna K. Szkaradkiewicz, Janina Stopa, Tomasz M. Karpiński
Archivum Immunologiae et Therapiae Experimentalis.2014; 62(6): 495. CrossRef
Dual Effects of Lactobacilli as a Cholesterol Assimilator and an Inhibitor of Gastrointestinal Pathogenic Bacteria
Amir Emami, Abdollah Bazargani
International Journal of Enteric Pathogens.2014;[Epub] CrossRef
16S rRNA PCR-Denaturing Gradient Gel Electrophoresis of Oral Lactobacillus casei Group and Their Phenotypic Appearances
S. Piwat, R. Teanpaisan
ISRN Microbiology.2013; 2013: 1. CrossRef
Incidence of Bacteriocins Produced by Food-Related Lactic Acid Bacteria Active towards Oral Pathogens
Georgia Zoumpopoulou, Eudoxie Pepelassi, William Papaioannou, Marina Georgalaki, Petros Maragkoudakis, Petros Tarantilis, Moschos Polissiou, Effie Tsakalidou, Konstantinos Papadimitriou
International Journal of Molecular Sciences.2013; 14(3): 4640. CrossRef
The pathogenicity of the Streptococcus genus
W. Krzyściak, K. K. Pluskwa, A. Jurczak, D. Kościelniak
European Journal of Clinical Microbiology & Infectious Diseases.2013; 32(11): 1361. CrossRef
Effect of Lactobacillus reuteri on the proliferation of Propionibacterium acnes and Staphylococcus epidermidis
Mi-Sun Kang, Jong-Suk Oh, Seok-Woo Lee, Hoi-Soon Lim, Nam-Ki Choi, Seon-Mi Kim
The Journal of Microbiology.2012; 50(1): 137. CrossRef
Anaerobic and microaerophilic pathogens in the biofilm formation on voice prostheses: A pilot study
Kristina Bertl, Beata Zatorska, Matthias Leonhard, Michael Matejka, Berit Schneider‐Stickler
The Laryngoscope.2012; 122(5): 1035. CrossRef
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Anita Khanafari, Sepideh Hosseini Porgham
Jundishapur Journal of Microbiology.2012; 5(4): 590. CrossRef

Journal Article

Screening-Level Assays for Potentially Human-Infectious Environmental Legionella spp.: Helen Y. Buse , Abby Brehm , Jorge W. Santo Domingo , Nicholas J. Ashbolt; J. Microbiol. 2011;49(2):200-207. Published online May 3, 2011; DOI: https://doi.org/10.1007/s12275-011-0233-z

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In spite of the fact that various Legionella species are isolated from nonclinical water settings, there is no standard method to determine whether environmental legionellae may be infectious to humans. Here we provide a screening-level approach based on an in vivo murine (A/J mouse) model and three in vitro proliferation assays using Acanthamoeba polyphaga, and THP-1 human and J774 murine macrophage cell lines to identify potentially human-infectious legionellae. As an initial demonstration the infectivity potential of three clinical (Legionella pneumophila, L. longbeacheae, and L. micdadei) and three environmental (L. dumoffii, L. maceachernii, and L. sainthelensi) legionellae were evaluated. A/J mice were intranasally infected and by 6 h post infection (p.i.), there were significant bacterial titers in the lungs. L. pneumophila, L. dumoffii, and L. micdadei densities were higher than L. longbeacheae, L. maceacherni, and L. sainthelensi at 24 h p.i. However, only L. pneumophila and L. micdadei persisted in the lungs after 48 h, indicating that the other isolates were rapidly cleared. Results from the in vitro assays showed that only L. pneumophila significantly multiplied within A. polyphaga, THP-1 and J774 cells after 72 h, but lysis of any of the in vitro hosts also flagged the strains for potential concern (e.g. L. dumoffii and L. micdadei). The results demonstrate the value of using multiple approaches to assess the potential level of pathogenicity of Legionella strains isolated from different environmental matrices.

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Lei Xu, Austin Sigler, Anna Chernatynskaya, Lindsey Rasmussen, Jingrang Lu, Endalkachew Sahle-Demessie, David Westenberg, Hu Yang, Honglan Shi
Analytical and Bioanalytical Chemistry.2024; 416(2): 419. CrossRef
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Applied and Environmental Microbiology.2018;[Epub] CrossRef
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Michael R. Grossi, Rafik Dey, Nicholas J. Ashbolt
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Severe Community Acquired Pneumonia Due to Legionella maceachernii Infection
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Applied and Environmental Microbiology.2013; 79(8): 2713. CrossRef

Research Support, Non-U.S. Gov't

Antibacterial Characteristics of Curcuma xanthorrhiza Extract on Streptococcus mutans Biofilm: Jung-Eun Kim , Hee-Eun Kim , Jae-Kwan Hwang , Ho-Jeong Lee , Ho-Keun Kwon , Baek-Il Kim; J. Microbiol. 2008;46(2):228-232. Published online June 11, 2008; DOI: https://doi.org/10.1007/s12275-007-0167-7

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This study evaluated the antibacterial effects of a natural Curcuma xanthorrhiza extract (Xan) on a Streptococcus mutans biofilm by examining the bactericidal activity, inhibition of acidogenesis and morphological alteration. Xan was obtained from the roots of a medicinal plant in Indonesia, which has shown selective <br><br>antibacterial effects on planktonic S. mutans. S. mutans biofilms were formed on slide glass over a 72 h period and treated with the following compounds for 5, 30, and 60 min: saline, 1% DMSO, 2 mg/ml chlorhexidine (CHX), and 0.1 mg/ml Xan. The Xan group exposed for 5 and 30 min showed significantly fewer colony forming units (CFU, 57.6 and 97.3%, respectively) than those exposed to 1% DMSO, the negative control group (P<0.05). These CFU were similar in number to those slides exposed to CHX, the positive control group. Xan showed similar bactericidal effect to that of CHX but the dose of Xan was one twentieth that of CHX. In addition, the biofilms treated with Xan and CHX maintained a neutral pH for 4 h, which indicates that Xan and CHX inhibit acid production. Scanning electron microscopy showed morphological changes in the cell wall and membrane of the Xan-treated biofilms; an uneven surface and a deformation in contour. Overall, natural Xan has strong bactericidal activity, inhibitory effects on acidogenesis, and alters the microstructure of S. mutans biofilm. In conclusion, Xan has potential in anti-S. mutans therapy for the prevention of dental caries.

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In vitro activities of Acacia nilotica (L.) Delile bark fractions against Oral Bacteria, Glucosyltransferase and as antioxidant
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Journal of Microbiology.2019; 57(5): 405. CrossRef
Galla chinensisextracts and calcium induce remineralization and antibacterial effects of enamel in aStreptococcus mutansbiofilm model
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Journal of Korean Academy of Oral Health.2018; 42(3): 90. CrossRef
Tooth enamel surface micro-hardness with dual species Streptococcus biofilm after exposure to Java turmeric (Curcuma xanthorrhiza Roxb.) extract
F R G Isjwara, S N Hasanah, Sri Utami, D F Suniarti
Journal of Physics: Conference Series.2017; 884: 012012. CrossRef
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International Journal of Clinical Pediatric Dentistry.2017; 10(2): 152. CrossRef
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Photodiagnosis and Photodynamic Therapy.2017; 20: 116. CrossRef
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Lamprini Karygianni, Ali Al-Ahmad, Aikaterini Argyropoulou, Elmar Hellwig, Annette C. Anderson, Alexios L. Skaltsounis
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Natural Product Communications.2011;[Epub] CrossRef
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Journal of Applied Microbiology.2010; 109(6): 2151. CrossRef
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The Journal of Microbiology.2008; 46(6): 744. CrossRef

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