Bacterial cells respond to changes in the environment by
adjusting their physiological reactions. In cascades of cellular
responses to stresses of various origins, rapid modulation
of RNA function is known to be an effective biochemical
adaptation. Among many factors affecting RNA function,
RNase III, a member of the phylogenetically highly conserved
endoribonuclease III family, plays a key role in posttranscriptional
regulatory pathways in Escherichia coli. In
this review, we provide an overview of the factors affecting
RNase III activity in E. coli.
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