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- The Revision of Lichen Flora Around Maxwell Bay, King George Island, Maritime Antarctic
- Jae Eun So , Josef P. Halda , Soon Gyu Hong , Jae&# , Ji Hee Kim
- J. Microbiol. 2023;61(2):159-173. Published online February 27, 2023
- DOI: https://doi.org/10.1007/s12275-023-00015-x
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Abstract
- Since the floristic study of lichens at the Barton and Weaver Peninsulas of King George Island in 2006, there have been intense investigations of the lichen flora of the two peninsulas as well as that of Fildes Peninsula and Ardley Island in Maxwell Bay, King George Island, South Shetland Islands, maritime Antarctic. In this study, a total of 104 species belonging to 53 genera, are identified from investigations of lichens that were collected in austral summer seasons from 2008 to 2016. Phenotypic and molecular analyses were incorporated for taxonomic identification. In particular, 31 species are found to be endemic to the Antarctic and 22 species are newly recorded to the Maxwell Bay region. Lepra dactylina, Stereocaulon caespitosum, and Wahlenbergiella striatula are newly recorded in the Antarctic, and the previously reported taxon Cladonia furcata is excluded from the formerly recorded list due to misidentification. We also provide ecological and geographical information about lichen associations and habitat preferences.
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- Lichens of Larsemann Hills and adjacent oases in the area of Prydz Bay (Princess Elizabeth Land and MacRobertson Land, Antarctica)
Mikhail Andreev (Mихаил АНДРЕЕВ)
Polar Science.2023; 38: 101009. CrossRef
- Lichens of Larsemann Hills and adjacent oases in the area of Prydz Bay (Princess Elizabeth Land and MacRobertson Land, Antarctica)
- Latent Kaposi’s sarcoma-associated herpesvirus infection in bladder cancer cells promotes drug resistance by reducing reactive oxygen species
- Suhyuk Lee , Jaehyuk Jang , Hyungtaek Jeon , Jisu Lee , Seung-Min Yoo , Jinsung Park , Myung-Shin Lee
- J. Microbiol. 2016;54(11):782-788. Published online October 29, 2016
- DOI: https://doi.org/10.1007/s12275-016-6388-x
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- 7 Crossref
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Abstract
- Kaposi’s sarcoma-associated herpesvirus (KSHV) is the major etiologic agent of Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman’s disease. Recent studies have indicated that KSHV can be detected at high frequency in patient-derived bladder cancer tissue and might be associated with the pathogenesis of bladder cancer. Bladder cancer is the second most common cancer of the genitourinary tract, and it has a high rate of recurrence. Because drug resistance is closely related to chemotherapy failure and cancer recurrence, we investigated whether KSHV infection is associated with drug resistance of bladder cancer cells. Some KSHV-infected bladder cancer cell lines showed resistance to an anti-cancer drug, cisplatin, possibly as a result of downregulation of reactive oxygen species. Additionally, drug resistance acquired from KSHV infection could partly be overcome by HDAC1 inhibitors. Taken together, the data suggest the possible role of KSHV in chemo-resistant bladder cancer, and indicate the therapeutic potential of HDAC1 inhibitors in drug-resistant bladder cancers associated with KSHV infection.
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Citations
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Development of KSHV vaccine platforms and chimeric MHV68-K-K8.1 glycoprotein for evaluating the
in vivo
immunogenicity and efficacy of KSHV vaccine candidates
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