The human gastrointestinal tract is colonized by multitudes
of microorganisms that exert beneficial effects on human
health. Mounting evidence suggests that intestinal microbiota
contributes to host resistance against enteropathogenic
bacterial infection. However, molecular details that account
for such an important role has just begun to be understood.
The commensal microbes in the intestine regulate gut homeostasis
through activating the development of host innate
immunity and producing molecules with antimicrobial activities
that directly inhibit propagation of pathogenic bacteria.
Understanding the protective roles of gut microbiota
will provide a better insight into the molecular basis that underlies
complicated interaction among host-pathogen-symbiont.
In this review, we highlighted recent findings that help
us broaden our knowledge of the intestinal ecosystem and
thereby come up with a better strategy for combating enteropathogenic
infection.
Citations
Citations to this article as recorded by
Probiotics for inflammatory bowel disease: Is there sufficient evidence? Yueying Ma, Dandan Yang, Jin Huang, Kunli Liu, Huirong Liu, Huangan Wu, Chunhui Bao Open Life Sciences.2024;[Epub] CrossRef
Human milk oligosaccharides combine with
Bifidobacterium longum
to form the “golden shield” of the infant intestine: metabolic strategies, health effects, and mechanisms of action
Shuo Yang, Junwu Cai, Qian Su, Qiaohui Li, Xiangchen Meng Gut Microbes.2024;[Epub] CrossRef
Effects of Interactions between Feeding Patterns and the Gut Microbiota on Pig Reproductive Performance Mingyu Wang, Jiaqi Yue, Guangquan Lv, Yaxin Wang, Ao Guo, Zhe Liu, Taiyong Yu, Gongshe Yang Animals.2024; 14(18): 2714. CrossRef
Effects of Clostridium butyricum on Growth Performance, Intestinal Health, and Disease Resistance of Hybrid Grouper (Epinephelus fuscoguttatus
♀
× E. lanceolatus
♂
) Fed with C Ling Pan, Weikang Li, Ruitao Xie, Hongyu Liu, Beiping Tan, Xiaohui Dong, Qihui Yang, Shuyan Chi, Shuang Zhang, Erchao Li Aquaculture Nutrition.2023; 2023: 1. CrossRef
The resistome and microbiome of wastewater treatment plant workers – The AWARE study Fanny Berglund, Daloha Rodríguez-Molina, Gratiela Gradisteanu Pircalabioru, Hetty Blaak, Mariana-Carmen Chifiriuc, Ilda Czobor Barbu, Carl-Fredrik Flach, Irina Gheorghe-Barbu, Luminița Măruțescu, Marcela Popa, Ana Maria de Roda Husman, Laura Wengenroth, H Environment International.2023; 180: 108242. CrossRef
Developmental changes of nutrient digestion in young lambs are influenced by weaning and associated with intestinal microbiota Chong Li, Guoxiu Wang, Qian Zhang, Yongliang Huang, Fadi Li, Weimin Wang Animal Biotechnology.2023; 34(4): 1362. CrossRef
Glycolysis characteristics of intracellular polysaccharides from Agaricus bitorquis (Quél.) sacc. Chaidam and its effects on intestinal flora from different altitudes of mice in vitro fermentation Shicheng Hu, Ke Gao, Yingchun Jiao, Zhenzhen Yuan Food Research International.2023; 173: 113382. CrossRef
The role of γδ T cells in the interaction between commensal and pathogenic bacteria in the intestinal mucosa Xiaoxiao Wu, Bing Gu, Huan Yang International Reviews of Immunology.2023; 42(6): 379. CrossRef
Mass Spectrometric Analysis of Bioactive Conditioned Media of Bacteria Isolated From Reptilian Gut Ruqaiyyah Siddiqui, Noor Akbar, Nelson Cruz Soares, Hamza Mohammad Al-Hroub, Mohammad Harb Semreen, Sutherland K Maciver, Naveed Ahmed Khan Future Science OA.2023;[Epub] CrossRef
Alteration of the Gut Microbiota in Missed Abortion Yi Chen, Xianqian Chen, Pingyu Chen, Xiuxia Chen, Lin Pan, Lihong Han, Tang Zhu Indian Journal of Microbiology.2023; 63(1): 106. CrossRef
Early Weaning Stress Induces Intestinal Microbiota Disturbance, Mucosal Barrier Dysfunction and Inflammation Response Activation in Pigeon Squabs Qianqian Xu, Huafeng Jian, Wenyan Zhao, Jiankui Li, Xiaoting Zou, Xinyang Dong Frontiers in Microbiology.2022;[Epub] CrossRef
Gut barrier disruption and chronic disease Jan Martel, Shih-Hsin Chang, Yun-Fei Ko, Tsong-Long Hwang, John D. Young, David M. Ojcius Trends in Endocrinology & Metabolism.2022; 33(4): 247. CrossRef
Modulation of Intestinal Barrier, Inflammatory Response, and Gut Microbiota by Pediococcus pentosaceus zy-B Alleviates Vibrio parahaemolyticus Infection in C57BL/6J Mice Rundong Wang, Yijia Deng, Yuhao Zhang, Xuepeng Li, Lijun Sun, Qi Deng, Ying Liu, Ravi Gooneratne, Jianrong Li Journal of Agricultural and Food Chemistry.2022; 70(6): 1865. CrossRef
Cholangiocyte derived carcinomas and local microbiota Ariel A. Arteta, Martha Milanes‐Yearsley, Nora Cardona‐Castro Journal of Hepato-Biliary-Pancreatic Sciences.2022; 29(10): 1084. CrossRef
Progress and prospects of the healthy human gut virome Stephen R Stockdale, Colin Hill Current Opinion in Virology.2021; 51: 164. CrossRef
The Role of Gut Barrier Dysfunction and Microbiome Dysbiosis in Colorectal Cancer Development Flavia Genua, Vedhika Raghunathan, Mazda Jenab, William M. Gallagher, David J. Hughes Frontiers in Oncology.2021;[Epub] CrossRef
An Escherichia coli strain with extra catalase activity protects against murine colitis by scavenging hydrogen peroxide and regulating regulatory t cell/interleukin-17 pathways Da Hye Kim, Jihye Park, Soochan Kim, Mi Young Yoon, Hyun Woo Ma, I.Seul Park, Mijeong Son, Ji Hyung Kim, Tae Il Kim, Won Ho Kim, Sang Sun Yoon, Seung Won Kim, Jae Hee Cheon Free Radical Biology and Medicine.2021; 174: 110. CrossRef
Description of Ornithinimicrobium ciconiae sp. nov., and Ornithinimicrobium avium sp. nov., isolated from the faeces of the endangered and near-threatened birds So-Yeon Lee, Hojun Sung, Pil Soo Kim, Hyun Sik Kim, Jae-Yun Lee, June-Young Lee, Yun-Seok Jeong, Euon Jung Tak, Jeong Eun Han, Dong-Wook Hyun, Jin-Woo Bae Journal of Microbiology.2021; 59(11): 978. CrossRef
Stimulation of Toll-Like Receptor 3 Diminishes Intracellular Growth of Salmonella Typhimurium by Enhancing Autophagy in Murine Macrophages Hyo-Ji Lee, Sun-Hye Lee, Ji-Hui Jeon, Hyo-Jung Kim, Eui-Kwon Jeong, Min-Jeong Kim, Young Mee Jung, Yu-Jin Jung Metabolites.2021; 11(9): 602. CrossRef
Infection prevention and control research priorities: what do we need to combat healthcare-associated infections and antimicrobial resistance? Results of a narrative literature review and survey analysis Yohann Lacotte, Christine Årdal, Marie-Cécile Ploy Antimicrobial Resistance & Infection Control.2020;[Epub] CrossRef
Microbiota–host interactions shape ageing dynamics Miriam Popkes, Dario Riccardo Valenzano Philosophical Transactions of the Royal Society B: Biological Sciences.2020; 375(1808): 20190596. CrossRef
Gut Microbiota: From the Forgotten Organ to a Potential Key Player in the Pathology of Alzheimer’s Disease Dong-Oh Seo, David M Holtzman, Michal Masternak The Journals of Gerontology: Series A.2020; 75(7): 1232. CrossRef
Interactions Between Rumen Microbes, VFAs, and Host Genes Regulate Nutrient Absorption and Epithelial Barrier Function During Cold Season Nutritional Stress in Tibetan Sheep Xiu Liu, Yuzhu Sha, Renqing Dingkao, Wei Zhang, Weibing Lv, Hong Wei, Hao Shi, Jiang Hu, Jiqing Wang, Shaobin Li, Zhiyun Hao, Yuzhu Luo Frontiers in Microbiology.2020;[Epub] CrossRef
Dual functional roles of the MyD88 signaling in colorectal cancer development Lu Wang, Kewei Yu, Xiang Zhang, Shuwen Yu Biomedicine & Pharmacotherapy.2018; 107: 177. CrossRef
Early-life sickness may predispose Siberian hamsters to behavioral changes following alterations of the gut microbiome in adulthood Kristyn E. Sylvia, Jessica E. Deyoe, Gregory E. Demas Brain, Behavior, and Immunity.2018; 73: 571. CrossRef
Effect of Early Weaning on the Intestinal Microbiota and Expression of Genes Related to Barrier Function in Lambs Chong Li, Weimin Wang, Ting Liu, Qian Zhang, Guoxiu Wang, Fadi Li, Fei Li, Xiangpeng Yue, Tingfu Li Frontiers in Microbiology.2018;[Epub] CrossRef
Guanosine tetra- and pentaphosphate increase antibiotic tolerance by reducing reactive oxygen species production in Vibrio cholerae Hwa Young Kim, Junhyeok Go, Kang-Mu Lee, Young Taek Oh, Sang Sun Yoon Journal of Biological Chemistry.2018; 293(15): 5679. CrossRef
A single gene of a commensal microbe affects host susceptibility to enteric infection Mi Young Yoon, Kyung Bae Min, Kang-Mu Lee, Yujin Yoon, Yaeseul Kim, Young Taek Oh, Keehoon Lee, Jongsik Chun, Byung-Yong Kim, Seok-Hwan Yoon, Insuk Lee, Chan Yeong Kim, Sang Sun Yoon Nature Communications.2016;[Epub] CrossRef
Antimicrobial Activity of Acidified Sodium Chlorite and Cell Free Culture Supernatent of Lactic Acid Bacteria against <i>Salmonella</i> Typhimurium Sangeeta Singh, Ajit Singh Yadav, Priyanka Bharti Journal of Biosciences and Medicines.2015; 03(11): 128. CrossRef
(p)ppGpp, a Small Nucleotide Regulator, Directs the Metabolic Fate of Glucose in Vibrio cholerae Young Taek Oh, Kang-Mu Lee, Wasimul Bari, David M. Raskin, Sang Sun Yoon Journal of Biological Chemistry.2015; 290(21): 13178. CrossRef