Skip Navigation
Skip to contents

Journal of Microbiology : Journal of Microbiology

OPEN ACCESS
SEARCH
Search

Search

Page Path
HOME > Search
1 "flavonol glycoside"
Filter
Filter
Article category
Keywords
Publication year
Research Support, Non-U.S. Gov't
Antiviral Effect of Flavonol Glycosides Isolated from the Leaf of Zanthoxylum piperitum on Influenza Virus
Song-Yi Ha , Hana Youn , Chang-Seon Song , Se Chan Kang , Jong Jin Bae , Hee Tae Kim , Kwang Min Lee , Tae Hoon Eom , In Su Kim , Jong Hwan Kwak
J. Microbiol. 2014;52(4):340-344.   Published online March 29, 2014
DOI: https://doi.org/10.1007/s12275-014-4073-5
  • 52 View
  • 0 Download
  • 27 Crossref
AbstractAbstract
The ethanol extract of Zanthoxylum piperitum (L.) DC. showed in vitro antiviral activity against influenza A virus. Three flavonol glycosides were isolated from the EtOAc fraction of Z. piperitum leaf by means of activity-guided chromatographic separation. Structures of isolated compounds were identified as quercetin 3-O-β-D-galactopyranoside (1), quercetin 3-O-α-L-rhamnopyranoside (2), kaempferol 3-O-α-L-rhamnopyranoside (3) by comparing their spectral data with literature values. The anti-influenza viral activity of isolates was evaluated using a plaque reduction assay against influenza A/NWS/33 (H1N1) virus. The compounds also were subjected to neuraminidase inhibition assay in influenza A/NWS/33 virus. Compounds 1-3 exhibited antiviral activity against an influenza A virus in vitro, and inhibited the neuraminidase activity at relatively high concentrations.

Citations

Citations to this article as recorded by  
  • A mini review on the prospects of Fagara zanthoxyloides extract based composites: a remedy for COVID-19 and associated replica?
    Abiodun Oladipo, Onome Ejeromedoghene, Ademola Adebayo, Olakunle Ogunyemi, George Egejuru
    Physical Sciences Reviews.2024; 9(2): 1065.     CrossRef
  • Determination of Biologically Active Compounds and Antioxidant Capacity In Vitro in Fruit of Small Cranberries (Vaccinium oxycoccos L.) Growing in Natural Habitats in Lithuania
    Mindaugas Liaudanskas, Rima Šedbarė, Valdimaras Janulis
    Antioxidants.2024; 13(9): 1045.     CrossRef
  • Preclinical evaluation of Zanthoxylum piperitum Benn., traditional muscle pain remedy, for joint inflammation
    Seung-Won Yun, Young-Jin Seo, Jeong Eun Kwon, Dae Won Park, Yeong-Geun Lee, Tae Hwan Choe, Seul-Ki Kim, Hak Sung Lee, Hyunggun Kim, Se Chan Kang
    Journal of Ethnopharmacology.2022; 286: 114921.     CrossRef
  • Hydroxy-β-sanshool isolated from Zanthoxylum piperitum (Japanese pepper) shortens the period of the circadian clock
    Tatsunosuke Tomita, Yasuhiro Kawano, Masahiro Kassai, Hiroyuki Onda, Yoshihiro Nakajima, Koyomi Miyazaki
    Food & Function.2022; 13(18): 9407.     CrossRef
  • Multifaceted antiviral therapeutic potential of dietary flavonoids: Emerging trends and future perspectives
    Varruchi Sharma, Nirmala Sehrawat, Ajay Sharma, Mukesh Yadav, Pawan Verma, Anil K. Sharma
    Biotechnology and Applied Biochemistry.2022; 69(5): 2028.     CrossRef
  • An Update on Promising Agents against COVID-19: Secondary Metabolites and Mechanistic Aspects
    Maryam Jamshidnia, Robert D.E. Sewell, Mahmoud Rafieian-Kopaei
    Current Pharmaceutical Design.2022; 28(29): 2415.     CrossRef
  • Novel Anti-Hepatitis B Virus Activity of Euphorbia schimperi and Its Quercetin and Kaempferol Derivatives
    Mohammad K. Parvez, Sarfaraz Ahmed, Mohammed S. Al-Dosari, Mazin A. S. Abdelwahid, Ahmed H. Arbab, Adnan J. Al-Rehaily, Mai M. Al-Oqail
    ACS Omega.2021; 6(43): 29100.     CrossRef
  • Zanthoxylum Species: A Comprehensive Review of Traditional Uses, Phytochemistry, Pharmacological and Nutraceutical Applications
    Innocent Uzochukwu Okagu, Joseph Chinedu Ndefo, Emmanuel Chigozie Aham, Chibuike C. Udenigwe
    Molecules.2021; 26(13): 4023.     CrossRef
  • Zanthoxylum Species: A Review of Traditional Uses, Phytochemistry and Pharmacology in Relation to Cancer, Infectious Diseases and Sickle Cell Anemia
    Innocent Uzochukwu Okagu, Joseph Chinedum Ndefo, Emmanuel Chigozie Aham, Chibuike. C. Udenigwe
    Frontiers in Pharmacology.2021;[Epub]     CrossRef
  • Evaluation of the Effectiveness and Safety of Zanthoxylum piperitum Leaf Extract against Mild Degenerative Osteoarthritis of Knee: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
    Ji-Hong Jeong, Soo-Hwan Lee, Hong-Ryoul Yoon, Soon-Joong Kim
    Journal of Korean Medicine Rehabilitation.2021; 31(4): 167.     CrossRef
  • Flavonoids as Promising Antiviral Agents against SARS-CoV-2 Infection: A Mechanistic Review
    Mohammad Amin Khazeei Tabari, Amin Iranpanah, Roodabeh Bahramsoltani, Roja Rahimi
    Molecules.2021; 26(13): 3900.     CrossRef
  • Identification of anti‐TMV active flavonoid glycosides and their mode of action on virus particles from Clematis lasiandra Maxim
    Yantao Li, Shengwei Ye, Zilong Hu, Nan Hao, Xin Bo, Huaguang Liang, Xiangrong Tian
    Pest Management Science.2021; 77(11): 5268.     CrossRef
  • Elucidation of Japanese pepper (Zanthoxylum piperitum De Candolle) domestication using RAD-Seq
    Maddumage Dona Ginushika Priyadarsh Premarathne, Nami Fukutome, Kazuaki Yamasaki, Fumiyo Hayakawa, Atsushi J. Nagano, Hisataka Mizuno, Nobuo Ibaragi, Yukio Nagano
    Scientific Reports.2021;[Epub]     CrossRef
  • Phytochemicals as Potential Curative Agents against Viral Infection: A Review
    Abhijeet Kumar, Anil Kumar Singh, Garima Tripathi
    Current Organic Chemistry.2020; 24(20): 2356.     CrossRef
  • Theacrine and strictinin, two major ingredients for the anti-influenza activity of Yunnan Kucha tea
    Pei-Rong Lin, Ping-Chung Kuo, Yue-Chiun Li, Cian-Fen Jhuo, Wei-Li Hsu, Jason T.C. Tzen
    Journal of Ethnopharmacology.2020; 262: 113190.     CrossRef
  • Investigation of Brassica juncea, Forsythia suspensa, and Inula britannica: phytochemical properties, antiviral effects, and safety
    Won-Young Bae, Hyeong-Yeop Kim, Kyoung-Sook Choi, Kyung Hoon Chang, Young-Ho Hong, Jongsu Eun, Na-Kyoung Lee, Hyun-Dong Paik
    BMC Complementary and Alternative Medicine.2019;[Epub]     CrossRef
  • Combating influenza: natural products as neuraminidase inhibitors
    Nisha Singh, Nawed Anjum, Ramesh Chandra
    Phytochemistry Reviews.2019; 18(1): 69.     CrossRef
  • Isobutylhydroxyamides from Sichuan Pepper and Their Protective Activity on PC12 Cells Damaged by Corticosterone
    Jiahuan Chen, Tao Zhang, Qiubo Zhang, Yang Liu, Lingyu Li, Jinguang Si, Zhongmei Zou, Huiming Hua
    Journal of Agricultural and Food Chemistry.2018; 66(13): 3408.     CrossRef
  • The Cranberry Extract Oximacro® Exerts in vitro Virucidal Activity Against Influenza Virus by Interfering With Hemagglutinin
    Anna Luganini, Maria E. Terlizzi, Gianluca Catucci, Gianfranco Gilardi, Massimo E. Maffei, Giorgio Gribaudo
    Frontiers in Microbiology.2018;[Epub]     CrossRef
  • Herbal Medicines with Antiviral Activity Against the Influenza Virus, a Systematic Review
    Ju-Young Lee, Michael Edward C. Abundo, Chang-Won Lee
    The American Journal of Chinese Medicine.2018; 46(08): 1663.     CrossRef
  • Flavonoids: promising natural compounds against viral infections
    Hovakim Zakaryan, Erik Arabyan, Adrian Oo, Keivan Zandi
    Archives of Virology.2017; 162(9): 2539.     CrossRef
  • Effects of high temperature steam treatment on microbial and phytochemical contents, antioxidant activities, chemical stability, and shelf life of oral liquid prepared from the leaves ofZanthoxylum bungeanumMaxim
    Yawei Zhang, Fengyuan He, Dengwu Li, Dongmei Wang
    Journal of Food Processing and Preservation.2017; 41(5): e13180.     CrossRef
  • Evaluation of Antiviral Activity of Zanthoxylum Species Against Picornaviruses
    Hwa-Jung Choi
    Osong Public Health and Research Perspectives.2016; 7(6): 400.     CrossRef
  • Application of the Extract of Zanthoxylum piperitum DC to Manufacturing Eco-friendly Antimicrobial Interior Fabric Blind Materials
    Li Rui Xie, Do Youn Jun, Ju Eun Park, Gi Hyun Kwon, Bonggeun Cho, Hyun Woo Park, Chang Woo Lee, Chang Young Kim, Hyo-Il Jung, Young Ho Kim
    Journal of Life Science.2016; 26(8): 936.     CrossRef
  • Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells
    Reo Nozaki, Toru Kono, Hiroki Bochimoto, Tsuyoshi Watanabe, Kaori Oketani, Yuichi Sakamaki, Naoto Okubo, Koji Nakagawa, Hiroshi Takeda
    Oncotarget.2016; 7(43): 70437.     CrossRef
  • Apigenin inhibits African swine fever virus infection in vitro
    Astghik Hakobyan, Erik Arabyan, Aida Avetisyan, Liana Abroyan, Lina Hakobyan, Hovakim Zakaryan
    Archives of Virology.2016; 161(12): 3445.     CrossRef
  • Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry
    Wenjiao Wu, Richan Li, Xianglian Li, Jian He, Shibo Jiang, Shuwen Liu, Jie Yang
    Viruses.2015; 8(1): 6.     CrossRef

Journal of Microbiology : Journal of Microbiology
TOP