Research Support, Non-U.S. Gov't
- Isolation and Identification of Lipopeptide Antibiotics from Paenibacillus elgii B69 with Inhibitory Activity Against Methicillin-Resistant Staphylococcus aureus
-
Rui Ding , Xue-Chang Wu , Chao-Dong Qian , Yi Teng , Ou Li , Zha-Jun Zhan , Yu-Hua Zhao
-
J. Microbiol. 2011;49(6):942-949. Published online December 28, 2011
-
DOI: https://doi.org/10.1007/s12275-011-1153-7
-
-
52
View
-
0
Download
-
39
Crossref
-
Abstract
-
Two lipopeptide antibiotics, pelgipeptins C and D, were isolated from Paenibacillus elgii B69 strain. The molecular masses of the two compounds were both determined to be 1,086 Da. Mass-spectrometry, amino acid analysis and NMR spectroscopy indicated that pelgipeptin C was the same compound as BMY-28160, while pelgipeptin D was identified as a new antibiotic of the polypeptin family. These two peptides were active against all the tested microorganisms, including antibiotic-resistant pathogenic bacterial strains such as methicillin-resistant Staphylococcus aureus (MRSA). Time-kill assays demonstrated that pelgipeptin D exhibited rapid and effective bactericidal action against MRSA at 4×MIC. Based on acute toxicity test, the intraperitoneal LD50 value of pelgipeptin D was slightly higher than that of the structurally related antimicrobial agent polymyxin B. Pelgipeptins are highly potent antibacterial and antifungal agents, particularly against MRSA, and warrant further investigation as possible therapeutic agents for bacteria infections resistant to currently available antibiotics.
-
Citations
Citations to this article as recorded by

- Correlation between sporogenesis and lipopeptide production in Paenibacillus elgii
Rosiane Andrade da Costa, Isadora Emanoela Pereira Costa Andrade, Thiago Fellipe de Araújo, Débora Luiza Albano Fulgêncio, Marise Leite Mendonça, Gabriel Iudy Yamaguchi Rocha, Raiana Moreira dos Santos, Cristine Chaves Barreto
Letters in Applied Microbiology.2024;[Epub] CrossRef -
The structure of lipopeptides impacts their antiviral activity and mode of action against SARS-CoV-2
in vitro
Alexis C. R. Hoste, Willy Smeralda, Aurélien Cugnet, Yves Brostaux, Magali Deleu, Mutien Garigliany, Philippe Jacques, Christopher A. Elkins
Applied and Environmental Microbiology.2024;[Epub] CrossRef - Effects of polypeptidin feeding on growth and intestinal flora of Apostichopus japonicus
Xiaolan Huang, Rubiao Xie, Ange Zou, Shuqing Zhang, Xiaohui Xu, Guohua Sun, Jianmin Yang
Aquaculture Reports.2024; 38: 102284. CrossRef - Lipopeptides development in cosmetics and pharmaceutical applications: A comprehensive review
Melania Pilz, Philipp Cavelius, Farah Qoura, Dania Awad, Thomas Brück
Biotechnology Advances.2023; 67: 108210. CrossRef - Secretome of Paenibacillus sp. S-12 provides an insight about its survival and possible pathogenicity
Kiran Kumari, Parva Kumar Sharma, Ying Ma, Rajnish Prakash Singh
Folia Microbiologica.2023; 68(4): 559. CrossRef - Co-occurrence of linear and cyclic pelgipeptins in broth cultures of Paenibacillus elgii AC13
Thiago Fellipe de Araújo, Daniel Barros Ortega, Rosiane Andrade da Costa, Isadora Emanoela Pereira Costa Andrade, Débora Luiza Albano Fulgêncio, Marise Leite Mendonça, Flávio Silva Costa, Michel Lopes Leite, Marcelo Henrique Soller Ramada, Cristine Chaves
Brazilian Journal of Microbiology.2021; 52(4): 1825. CrossRef - Screening and Characterization of Two Extracellular Polysaccharide-Producing Bacteria from the Biocrust of the Mu Us Desert
Zhanfang Xue, Shuting Zhao, Nomin Bold, Jianguo Zhang, Zhimin Hu, Xiaofeng Hu, Ying Gao, Shaolin Chen, Yahong Wei
Molecules.2021; 26(18): 5521. CrossRef - In vitro antifungal activity of pelgipeptins against human pathogenic fungi and Candida albicans biofilms
Débora Luíza Albano Fulgêncio, Rosiane Andrade da Costa, Fernanda Guilhelmelli, Calliandra Maria de Souza Silva, Daniel Barros Ortega, Thiago Fellipe de Araujo, Philippe Spezia Silva, Ildinete Silva-Pereira, Patrícia Albuquerque, Cristine Chaves Barreto
AIMS Microbiology.2021; 7(1): 28. CrossRef - Biological Control of Tomato Bacterial Wilt, Kimchi Cabbage Soft Rot, and Red Pepper Bacterial Leaf Spot Using Paenibacillus elgii JCK-5075
Khanh Duy Le, Jueun Kim, Nan Hee Yu, Bora Kim, Chul Won Lee, Jin-Cheol Kim
Frontiers in Plant Science.2020;[Epub] CrossRef - Structure and antifungal activity of pelgipeptins from Paenibacillus elgii against phytopathogenic fungi
Jueun Kim, Khanh Duy Le, Nan Hee Yu, Jae Il Kim, Jin-Cheol Kim, Chul Won Lee
Pesticide Biochemistry and Physiology.2020; 163: 154. CrossRef - Strategies for recombinant production of antimicrobial peptides with pharmacological potential
Kamila Botelho Sampaio de Oliveira, Michel Lopes Leite, Gisele Regina Rodrigues, Harry Morales Duque, Rosiane Andrade da Costa, Victor Albuquerque Cunha, Lorena Sousa de Loiola Costa, Nicolau Brito da Cunha, Octavio Luiz Franco, Simoni Campos Dias
Expert Review of Clinical Pharmacology.2020; 13(4): 367. CrossRef - A broad-spectrum antibiotic adjuvant reverses multidrug-resistant Gram-negative pathogens
Meirong Song, Yuan Liu, Xiaoyong Huang, Shuangyang Ding, Yang Wang, Jianzhong Shen, Kui Zhu
Nature Microbiology.2020; 5(8): 1040. CrossRef - Antifungal activity of various chitinolytic bacteria against Colletotrichum in pepper
Muhammad Anees, Muhammad Abid, Shafiq ur Rehman, Nadeem Ahmed, Muhammad Ashraf, Lixin Zhang, Kil Yong Kim
Plant Protection Science.2019; 55(2): 109. CrossRef - Checkerboard testing method indicates synergic effect of pelgipeptins against multidrug resistant Klebsiella pneumoniae
Rosiane A. Costa, Daniel B. Ortega, Débora L.A. Fulgêncio, Flávio S. Costa, Thiago F. Araújo, Cristine C. Barreto
Biotechnology Research and Innovation.2019; 3(1): 187. CrossRef - Biocontrol of Botrytis cinerea by chitin-based cultures of Paenibacillus elgii HOA73
Young Cheol Kim, Jin Young Hur, Seur Kee Park
European Journal of Plant Pathology.2019; 155(1): 253. CrossRef - Bacillus and Paenibacillus secreted polyketides and peptides involved in controlling human and plant pathogens
Snizhana Olishevska, Arvin Nickzad, Eric Déziel
Applied Microbiology and Biotechnology.2019; 103(3): 1189. CrossRef - Bacillaceae -derived peptide antibiotics since 2000
Pengchao Zhao, Yun Xue, Weina Gao, Jinghua Li, Xiangyang Zu, Dongliao Fu, Xuefei Bai, Yanjun Zuo, Zhigang Hu, Fengshou Zhang
Peptides.2018; 101: 10. CrossRef - Isolation and structural elucidation of pelgipeptin E, a novel pore-forming pelgipeptin analog from Paenibacillus elgii with low hemolytic activity
Jueun Kim, Pyoung Il Kim, Ki Moon Bong, Jae Il Kim, Song Yub Shin, Jaekyeong Song, Hye Jung Min, Chul Won Lee
The Journal of Antibiotics.2018; 71(12): 1008. CrossRef -
First Insights into the Draft Genome Sequence of the Endophyte
Paenibacillus amylolyticus
Strain GM1FR, Isolated from
Festuca rubra
L
Anja Poehlein, Jacqueline Hollensteiner, Sandra Granzow, Bernd Wemheuer, Stefan Vidal, Franziska Wemheuer
Genome Announcements.2018;[Epub] CrossRef - The first total synthesis and solution structure of a polypeptin, PE2, a cyclic lipopeptide with broad spectrum antibiotic activity
Simon J. Mountford, Biswaranjan Mohanty, Kade D. Roberts, Heidi H. Yu, Martin J. Scanlon, Roger L. Nation, Tony Velkov, Jian Li, Philp E. Thompson
Organic & Biomolecular Chemistry.2017; 15(34): 7173. CrossRef - New Paenibacillus strain produces a family of linear and cyclic antimicrobial lipopeptides: cyclization is not essential for their antimicrobial activity
En Huang, Xu Yang, Liwen Zhang, Sun Hee Moon, Ahmed E. Yousef
FEMS Microbiology Letters.2017;[Epub] CrossRef -
Gentamicin‐gold nanoparticles conjugate: a contrast agent for X‐ray imaging of infectious foci due to
Staphylococcus aureus
Azam Ahangari, Mojtaba Salouti, Faranak Saghatchi
IET Nanobiotechnology.2016; 10(4): 190. CrossRef - Lipopeptides from Bacillus and Paenibacillus spp.: A Gold Mine of Antibiotic Candidates
Stephen A. Cochrane, John C. Vederas
Medicinal Research Reviews.2016; 36(1): 4. CrossRef - Identification and classification of known and putative antimicrobial compounds produced by a wide variety of Bacillales species
Xin Zhao, Oscar P. Kuipers
BMC Genomics.2016;[Epub] CrossRef - Newly Isolated Paenibacillus tyrfis sp. nov., from Malaysian Tropical Peat Swamp Soil with Broad Spectrum Antimicrobial Activity
Yoong-Kit Aw, Kuan-Shion Ong, Learn-Han Lee, Yuen-Lin Cheow, Catherine M. Yule, Sui-Mae Lee
Frontiers in Microbiology.2016;[Epub] CrossRef - Lipopeptide surfactants: Production, recovery and pore forming capacity
Mnif Inès, Ghribi Dhouha
Peptides.2015; 71: 100. CrossRef - Potential therapeutic applications of microbial surface-active compounds
Letizia Fracchia, Jareer J. Banat, Massimo Cavallo, Chiara Ceresa, Ibrahim M. Banat
AIMS Bioengineering.2015; 2(3): 144. CrossRef - Inhibitory effect of SeO2 on cell growth of methicillin-resistant Staphylococcus aureus
Yeong-Hwan Han
The Korean Journal of Microbiology.2015; 51(4): 444. CrossRef - Genome mining: Prediction of lipopeptides and polyketides from Bacillus and related Firmicutes
Gajender Aleti, Angela Sessitsch, Günter Brader
Computational and Structural Biotechnology Journal.2015; 13: 192. CrossRef - Characterization of Novel Fusaricidins Produced by Paenibacillus polymyxa-M1 Using MALDI-TOF Mass Spectrometry
Joachim Vater, Ben Niu, Kristin Dietel, Rainer Borriss
Journal of the American Society for Mass Spectrometry.2015; 26(9): 1548. CrossRef - Genomic comparison of sporeforming bacilli isolated from milk
Andrea I Moreno Switt, Alexis D Andrus, Matthew L Ranieri, Renato H Orsi, Reid Ivy, Henk C den Bakker, Nicole H Martin, Martin Wiedmann, Kathryn J Boor
BMC Genomics.2014;[Epub] CrossRef - Characterization of antifungal activity of Paenibacillus ehimensis KWN38 against soilborne phytopathogenic fungi belonging to various taxonomic groups
Kyaw Wai Naing, Muhammad Anees, Sang Jun Kim, Yi Nam, Young Cheol Kim, Kil Yong Kim
Annals of Microbiology.2014; 64(1): 55. CrossRef - Low-Molecular-Weight Metabolites Secreted by Paenibacillus larvae as Potential Virulence Factors of American Foulbrood
Hedwig-Annabell Schild, Sebastian W. Fuchs, Helge B. Bode, Bernd Grünewald, H. L. Drake
Applied and Environmental Microbiology.2014; 80(8): 2484. CrossRef - A Novel Depsipeptide Produced by Paenibacillus alvei 32 Isolated from a Cystic fibrosis Patient
Romain Chevrot, Sandrine Didelot, Larissa Van den Bossche, Fatoumata Tambadou, Thibault Caradec, Pierre Marchand, Esther Izquierdo, Valérie Sopéna, Jocelyne Caillon, Cyrille Barthélémy, Ann Van Schepdael, Jos Hoogmartens, Eric Rosenfeld
Probiotics and Antimicrobial Proteins.2013; 5(1): 18. CrossRef - Developing new antibacterials through natural product research
Herbert A Kirst
Expert Opinion on Drug Discovery.2013; 8(5): 479. CrossRef - Antibacterial activity of extracellular compounds produced by a Pseudomonas strain against methicillin-resistant Staphylococcus aureus (MRSA) strains
Viviane F Cardozo, Admilton G Oliveira, Erick K Nishio, Marcia RE Perugini, Célia GTJ Andrade, Wanderley D Silveira, Nelson Durán, Galdino Andrade, Renata KT Kobayashi, Gerson Nakazato
Annals of Clinical Microbiology and Antimicrobials.2013;[Epub] CrossRef - Isolation and partial characterization of cyclic lipopeptide antibiotics produced by Paenibacillus ehimensis B7
Zhaohui Huang, Yu Hu, Linfei Shou, Mingxu Song
BMC Microbiology.2013; 13(1): 87. CrossRef - Complete Genome Sequence of Paenibacillus strain Y4.12MC10, a Novel Paenibacillus lautus strain Isolated from Obsidian Hot Spring in Yellowstone National Park
David A. Mead, Susan Lucas, Alex Copeland, Alla Lapidus, Jan-Feng Cheng, David C. Bruce, Lynne A. Goodwin, Sam Pitluck, Olga Chertkov, Xiaojing Zhang, John C. Detter, Cliff S. Han, Roxanne Tapia, Miriam Land, Loren J. Hauser, Yun-juan Chang, Nikos C. Kyrp
Standards in Genomic Sciences.2012; 6(3): 381. CrossRef - Identification and functional analysis of gene cluster involvement in biosynthesis of the cyclic lipopeptide antibiotic pelgipeptin produced by Paenibacillus elgii
Chao-Dong Qian, Tian-Zhe Liu, Shuang-Lin Zhou, Rui Ding, Wen-Peng Zhao, Ou Li, Xue-Chang Wu
BMC Microbiology.2012;[Epub] CrossRef
Journal Article
- Cyclic Lipopeptide Profile of Three Bacillus subtilis Strains; Antagonists of Fusarium Head Blight
-
Christopher A. Dunlap , David A. Schisler , Neil P. Price , Steven F. Vaughn
-
J. Microbiol. 2011;49(4):603-609. Published online September 2, 2011
-
DOI: https://doi.org/10.1007/s12275-011-1044-y
-
-
74
View
-
0
Download
-
59
Crossref
-
Abstract
-
The objective of the study was to identify the lipopetides associated with three Bacillus subtilis strains.
The strains are antagonists of Gibberella zeae, and have been shown to be effective in reducing Fusarium
head blight in wheat. The lipopeptide profile of three B. subtilis strains (AS43.3, AS43.4, and OH131.1)
was determined using mass spectroscopy. Strains AS43.3 and AS43.4 produced the anti-fungal lipopeptides
from the iturin and fengycin family during the stationary growth phase. All three strains produced the
lipopeptide surfactin at different growth times. Strain OH131.1 only produced surfactin under these conditions.
The antifungal activity of the culture supernatant and individual lipopeptides was determined by the inhibition
of G. zeae. Cell-free supernatant from strains AS43.3 and AS43.4 demonstrated strong antibiosis of G. zeae,
while strain OH131.1 had no antibiosis activity. These results suggest a different mechanism of antagonism
for strain OH131.1, relative to AS43.3 and AS43.4.
-
Citations
Citations to this article as recorded by

- Bacillus velezensis RC218 and emerging biocontrol agents against Fusarium graminearum and Fusarium poae in barley: in vitro, greenhouse and field conditions
María Silvina Alaniz Zanon, Lorenzo Rosales Cavaglieri, Juan Manuel Palazzini, Sofía Noemí Chulze, María Laura Chiotta
International Journal of Food Microbiology.2024; 413: 110580. CrossRef - Preparation of Bacillus pumilus loaded electrosprayed nanoparticles as a plant protective against postharvest fungal decay
Meyrem Vehapi, Benan İnan, Selma Kayacan-Cakmakoglu, Osman Sagdic, Didem Balkanlı Özçimen
European Journal of Plant Pathology.2024; 168(1): 121. CrossRef - Synthetic and Natural Antifungal Substances in Cereal Grain Protection: A Review of Bright and Dark Sides
Tomasz Szczygieł, Anna Koziróg, Anna Otlewska
Molecules.2024; 29(16): 3780. CrossRef - Composition and activity of antifungal lipopeptides produced by Bacillus spp. in daqu fermentation
Zhen Li, Kleinberg X. Fernandez, John C. Vederas, Michael G. Gänzle
Food Microbiology.2023; 111: 104211. CrossRef - Characterization of lipopeptide produced by Bacillus altitudinis Q7 and inhibitory effect on Alternaria alternata
Pengfei Guo, Fengrui Yang, Shuhong Ye, Jing Li, Fengjun Shen, Yan Ding
Journal of Basic Microbiology.2023; 63(1): 26. CrossRef - Classification and Multifaceted Potential of Secondary Metabolites Produced by Bacillus subtilis Group: A Comprehensive Review
Sajid Iqbal, Farida Begum, Ali A. Rabaan, Mohammed Aljeldah, Basim R. Al Shammari, Abdulsalam Alawfi, Amer Alshengeti, Tarek Sulaiman, Alam Khan
Molecules.2023; 28(3): 927. CrossRef - Research Advances in Wheat Breeding and Genetics for Powdery Mildew Resistance
Myoung-Hui Lee, Sumin Hong, Kyeong-Min Kim, Yurim Kim, Sun-Hwa Kwak, Kyeong-Hoon Kim, Chon-Sik Kang, Chul Soo Park, Youngjun Mo, Changhyun Choi
Korean Journal of Breeding Science.2023; 55(3): 218. CrossRef - GC/EI/MS and 1H NMR Metabolomics Reveal the Effect of an Olive Tree Endophytic Bacillus sp. Lipopeptide Extract on the Metabolism of Colletotrichum acutatum
Evgenia-Anna Papadopoulou, Apostolis Angelis, Alexios-Leandros Skaltsounis, Konstantinos A. Aliferis
Metabolites.2023; 13(4): 462. CrossRef - Effect of Chitosan Coating for Efficient Encapsulation and Improved Stability under Loading Preparation and Storage Conditions of Bacillus Lipopeptides
Beom Ryong Kang, Joon Seong Park, Gwang Rok Ryu, Woo-Jin Jung, Jun-Seok Choi, Hye-Min Shin
Nanomaterials.2022; 12(23): 4189. CrossRef - Target Mechanism of Iturinic Lipopeptide on Differential Expression Patterns of Defense-Related Genes against Colletotrichum acutatum in Pepper
Joon Seong Park, Gwang Rok Ryu, Beom Ryong Kang
Plants.2022; 11(9): 1267. CrossRef - Maize Root Exudates Recruit Bacillus amyloliquefaciens OR2-30 to Inhibit Fusarium graminearum Infection
Shanshan Xie, Lin Jiang, Qin Wu, Wenkun Wan, Yutian Gan, Lingling Zhao, Jiajia Wen
Phytopathology®.2022; 112(9): 1886. CrossRef - Specific features of antagonism of Bacillus bacteria against toxinogenic Fusarium fungi in protecting plants against disease and contamination with mycotoxins (review)
T. M. Sidorova, A. M. Asaturova, V. V. Allakhverdyan
South of Russia: ecology, development.2022; 16(4): 86. CrossRef - Efficiency of durum wheat seeds biopriming by rhizobacteria in the biocontrol of Fusarium culmorum and Fusarium chlamydosporum infecting durum wheat in Algeria
Amor Bencheikh, Meziti Hicham, Daichi Barkahoum Meriem, Gharzouli Asma, Belkadi Khalida, Noureddine Rouag
Archives of Phytopathology and Plant Protection.2022; 55(6): 653. CrossRef - Isolation of lipopeptide antibiotics from Bacillus siamensis: a potential biocontrol agent for Fusarium graminearum
Yanhong Huang, Xingrong Zhang, Hui Xu, Fan Zhang, Xuelin Zhang, Yongheng Yan, Lianzhi He, Jianjun Liu
Canadian Journal of Microbiology.2022; 68(6): 403. CrossRef - Biocontrol prospective of Bacillus siamensis-AMU03 against Soil-borne fungal pathogens of potato tubers
Touseef Hussain, Abrar Ahmad Khan
Indian Phytopathology.2022; 75(1): 179. CrossRef - Distribution, pathogenicity and disease control of Fusarium tricinctum
Yun Wang, Ruoyu Wang, Yuexia Sha
Frontiers in Microbiology.2022;[Epub] CrossRef - In vitro antifungal potential of surfactin isolated from rhizospheric Bacillus thuringiensis Berliner 1915 against maize (Zea mays L.) fungal phytopathogen Fusarium graminearum Schwabe
Muddasir KHAN, Muhammad SALMAN, Syed Hussain SHAH, Muhammad ISRAR
Acta agriculturae Slovenica.2021; 117(4): 1. CrossRef - Interactions with plant pathogens influence lipopeptides production and antimicrobial activity of Bacillus subtilis strain PTB185
Louis Cossus, Florence Roux-Dalvai, Isabelle Kelly, Thi Thuy An Nguyen, Hani Antoun, Arnaud Droit, Russell J. Tweddell
Biological Control.2021; 154: 104497. CrossRef - Bacillus species as potential biocontrol agents against citrus diseases
Kai Chen, Zhonghuan Tian, Hua He, Chao-an Long, Fatang Jiang
Biological Control.2020; 151: 104419. CrossRef - Surfactin-producing Bacillus velezensis 1B-23 and Bacillus sp. 1D-12 protect tomato against bacterial canker caused by Clavibacter michiganensis subsp. michiganensis
Matthew Laird, David Piccoli, Brian Weselowski, Tim McDowell, Justin Renaud, Jacqueline MacDonald, Ze-Chun Yuan
Journal of Plant Pathology.2020; 102(2): 451. CrossRef - Antifungal evaluation of fengycin isoforms isolated from Bacillus amyloliquefaciens PPL against Fusarium oxysporum f. sp. lycopersici
Beom Ryong Kang, Joon Seong Park, Woo-Jin Jung
Microbial Pathogenesis.2020; 149: 104509. CrossRef - The Mode of Action of Bacillus Species against Fusarium graminearum, Tools for Investigation, and Future Prospects
Khayalethu Ntushelo, Lesiba Klaas Ledwaba, Molemi Evelyn Rauwane, Oluwafemi Ayodeji Adebo, Patrick Berka Njobeh
Toxins.2019; 11(10): 606. CrossRef - Characterization of Antagonistic Bacillus methylotrophicus Isolated From Rhizosphere and Its Biocontrol Effects on Maize Stalk Rot
Xingkai Cheng, Xiaoxue Ji, Yanzhen Ge, Jingjing Li, Wenzhe Qi, Kang Qiao
Phytopathology®.2019; 109(4): 571. CrossRef - Identification of lipopeptides from Bacillus strain Q11 with ability to inhibit the germination of Penicillium expansum, the etiological agent of postharvest blue mold disease
José Luis Rodríguez-Chávez, Yara Suhan Juárez-Campusano, Guillermo Delgado, Juan Ramiro Pacheco Aguilar
Postharvest Biology and Technology.2019; 155: 72. CrossRef - Lipopeptide mediated biocontrol activity of endophytic Bacillus subtilis against fungal phytopathogens
Dibya Jyoti Hazarika, Gunajit Goswami, Trishnamoni Gautom, Assma Parveen, Pompi Das, Madhumita Barooah, Robin Chandra Boro
BMC Microbiology.2019;[Epub] CrossRef - Antifungal Activities of Bacillus subtilis Lipopeptides to Two Venturia inaequalis Strains Possessing Different Tebuconazole Sensitivity
Hélène Desmyttere, Caroline Deweer, Jérôme Muchembled, Karin Sahmer, Justine Jacquin, François Coutte, Philippe Jacques
Frontiers in Microbiology.2019;[Epub] CrossRef - Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group
Simon Caulier, Catherine Nannan, Annika Gillis, Florent Licciardi, Claude Bragard, Jacques Mahillon
Frontiers in Microbiology.2019;[Epub] CrossRef - Biofilm formation and regulation of salicylic acid-inducible genes expression in Arabidopsis by Algerian indigenous bacteria from wheat and potatoes rhizospheres in semi-arid Sétif region
Asma Benslim, Samia Mezaache-Aichour, Nora Haichour, Kamel Aissat, Mohamed Mihoub Zerroug
Archives of Microbiology.2018; 200(9): 1395. CrossRef - Effects of bacillomycin D homologues produced by Bacillus amyloliquefaciens 83 on growth and viability of Colletotrichum gloeosporioides at different physiological stages
Agustín Luna-Bulbarela, Raunel Tinoco-Valencia, Gerardo Corzo, Kohei Kazuma, Katsuhiro Konno, Enrique Galindo, Leobardo Serrano-Carreón
Biological Control.2018; 127: 145. CrossRef - Tackling maize fusariosis: in search of Fusarium graminearum biosuppressors
Adetomiwa Ayodele Adeniji, Olubukola Oluranti Babalola
Archives of Microbiology.2018; 200(8): 1239. CrossRef - Fungal Competitors Affect Production of Antimicrobial Lipopeptides in Bacillus subtilis Strain B9–5
Stefanie DeFilippi, Emma Groulx, Merna Megalla, Rowida Mohamed, Tyler J. Avis
Journal of Chemical Ecology.2018; 44(4): 374. CrossRef - Differential antagonistic responses of Bacillus pumilus MSUA3 against Rhizoctonia solani and Fusarium oxysporum causing fungal diseases in Fagopyrum esculentum Moench
Mohit Agarwal, Shrivardhan Dheeman, Ramesh Chand Dubey, Pradeep Kumar, Dinesh Kumar Maheshwari, Vivek K. Bajpai
Microbiological Research.2017; 205: 40. CrossRef - Challenges facing the biological control strategies for the management of Fusarium Head Blight of cereals caused by F. graminearum
Fabienne Legrand, Adeline Picot, José Francisco Cobo-Díaz, Wen Chen, Gaétan Le Floch
Biological Control.2017; 113: 26. CrossRef - Screening concepts, characterization and structural analysis of microbial-derived bioactive lipopeptides: a review
Piotr Biniarz, Marcin Łukaszewicz, Tomasz Janek
Critical Reviews in Biotechnology.2017; 37(3): 393. CrossRef - Antimycotic activity of fengycin C biosurfactant and its interaction with phosphatidylcholine model membranes
Lina María González-Jaramillo, Francisco José Aranda, José Antonio Teruel, Valeska Villegas-Escobar, Antonio Ortiz
Colloids and Surfaces B: Biointerfaces.2017; 156: 114. CrossRef - High-performance thin-layer chromatography (HPTLC) for the simultaneous quantification of the cyclic lipopeptides Surfactin, Iturin A and Fengycin in culture samples of Bacillus species
Mareen Geissler, Claudia Oellig, Karin Moss, Wolfgang Schwack, Marius Henkel, Rudolf Hausmann
Journal of Chromatography B.2017; 1044-1045: 214. CrossRef - Microbial Inhibition of Fusarium Pathogens and Biological Modification of Trichothecenes in Cereal Grains
Urszula Wachowska, Danuta Packa, Marian Wiwart
Toxins.2017; 9(12): 408. CrossRef - Imidazolium salts with antifungal potential for the control of head blight of wheat caused by Fusarium graminearum
A.D. Ribas, E.M. Del Ponte, A.M. Dalbem, D. Dalla-Lana, C. Bündchen, R.K. Donato, H.S. Schrekker, A.M. Fuentefria
Journal of Applied Microbiology.2016; 121(2): 445. CrossRef - Identification and characterization of a library of surfactins and fengycins from a marine endophytic Bacillus sp.
Divya Nair, Muralidharan Vanuopadath, Bipin G. Nair, Jayashree Gopalakrishna Pai, Sudarslal Sadasivan Nair
Journal of Basic Microbiology.2016; 56(11): 1159. CrossRef - Quantification of antifungal lipopeptide gene expression levels in Bacillus subtilis B1 during antagonism against sapstain fungus on rubberwood
K.L. Sajitha, Suma Arun Dev
Biological Control.2016; 96: 78. CrossRef - Production and identification of iturin A lipopeptide fromBacillus methyltrophicusTEB1 for control ofPhoma tracheiphila
Leila Kalai-Grami, Ines Karkouch, Omar Naili, Imen Ben Slimene, Salem Elkahoui, Roudaina Ben Zekri, Ines Touati, Monia Mnari-Hattab, Mohamed Rabeh Hajlaoui, Ferid Limam
Journal of Basic Microbiology.2016; 56(8): 864. CrossRef - Genomic analysis of Bacillus subtilis OH 131.1 and co-culturing with Cryptococcus flavescens for control of Fusarium head blight
Christopher A. Dunlap, David A. Schisler, Michael J. Bowman, Alejandro P. Rooney
Plant Gene.2015; 2: 1. CrossRef - Biological control as a strategy to reduce the impact of mycotoxins in peanuts, grapes and cereals in Argentina
S.N. Chulze, J.M. Palazzini, A. M. Torres, G. Barros, M.L. Ponsone, R. Geisen, M. Schmidt-Heydt, J. Köhl
Food Additives & Contaminants: Part A.2015; 32(4): 471. CrossRef - Microencapsulation of Bacillus subtilis B99-2 and its biocontrol efficiency against Rhizoctonia solani in tomato
Xin Ma, Xiaobing Wang, Juan Cheng, Xin Nie, Xuexin Yu, Yongtian Zhao, Wei Wang
Biological Control.2015; 90: 34. CrossRef - Endophytic bacteria from wheat grain as biocontrol agents of Fusarium graminearum and deoxynivalenol production in wheat
D. Pan, A. Mionetto, S. Tiscornia, L. Bettucci
Mycotoxin Research.2015; 31(3): 137. CrossRef - Effects of Bio-organic Fertilizers Produced by FourBacillus amyloliquefaciensStrains on Banana Fusarium Wilt Disease
Jingjing Wang, Yan Zhao, Yunze Ruan
Compost Science & Utilization.2015; 23(3): 185. CrossRef - Potential of Pseudomonas chlororaphis subsp. aurantiaca Strain Pcho10 as a Biocontrol Agent Against Fusarium graminearum
Weiqun Hu, Qixun Gao, Mohamed Sobhy Hamada, Dawood Hosni Dawood, Jingwu Zheng, Yun Chen, Zhonghua Ma
Phytopathology®.2014; 104(12): 1289. CrossRef -
Complete Genome Sequence for the
Fusarium
Head Blight Antagonist Bacillus amyloliquefaciens Strain TrigoCor 1448
Beth A. Nelson, Preethi Ramaiya, Alfredo Lopez de Leon, Ravi Kumar, Austin Crinklaw, Eliana Jolkovsky, Julia M. Crane, Gary C. Bergstrom, Michael W. Rey
Genome Announcements.2014;[Epub] CrossRef - Isolation and identification of cyclic lipopeptides from Paenibacillus ehimensis, strain IB-X-b
Gleb Aktuganov, Jouni Jokela, Henri Kivelä, Elvira Khalikova, Alexander Melentjev, Nailia Galimzianova, Lyudmila Kuzmina, Petri Kouvonen, Juha-Pekka Himanen, Petri Susi, Timo Korpela
Journal of Chromatography B.2014; 973: 9. CrossRef - Cyclic Lipopeptides from Bacillus subtilis ABS–S14 Elicit Defense-Related Gene Expression in Citrus Fruit
Waewruedee Waewthongrak, Wichitra Leelasuphakul, Greg McCollum, Silvia Mazzuca
PLoS ONE.2014; 9(10): e109386. CrossRef - Antagonistic Action of Bacillus subtilis Strain SG6 on Fusarium graminearum
Yueju Zhao, Jonathan Nimal Selvaraj, Fuguo Xing, Lu Zhou, Yan Wang, Huimin Song, Xinxin Tan, Lichao Sun, Lancine Sangare, Yawa Minnie Elodie Folly, Yang Liu, Adam Driks
PLoS ONE.2014; 9(3): e92486. CrossRef - Lipopeptides, a novel protein, and volatile compounds contribute to the antifungal activity of the biocontrol agent Bacillus atrophaeus CAB-1
Xiaoyun Zhang, Baoqing Li, Ye Wang, Qinggang Guo, Xiuyun Lu, Shezeng Li, Ping Ma
Applied Microbiology and Biotechnology.2013; 97(21): 9525. CrossRef - Genomic analysis and secondary metabolite production in Bacillus amyloliquefaciens AS 43.3: A biocontrol antagonist of Fusarium head blight
Christopher A. Dunlap, Michael J. Bowman, David A. Schisler
Biological Control.2013; 64(2): 166. CrossRef - Overview of some recent research developments in fusarium head blight of wheat
Jeannie Gilbert, Steve Haber
Canadian Journal of Plant Pathology.2013; 35(2): 149. CrossRef - Iturin Levels on Wheat Spikes Linked to Biological Control of Fusarium Head Blight by Bacillus amyloliquefaciens
J. M. Crane, D. M. Gibson, R. H. Vaughan, G. C. Bergstrom
Phytopathology®.2013; 103(2): 146. CrossRef - Biological control of winter wheat pathogens with the use of antagonisticSphingomonasbacteria under greenhouse conditions
Urszula Wachowska, Witold Irzykowski, Małgorzata Jędryczka, Anna D. Stasiulewicz-Paluch, Katarzyna Głowacka
Biocontrol Science and Technology.2013; 23(10): 1110. CrossRef - Production of schizophyllan from distiller’s dried grains with solubles by diverse strains of Schizophyllum commune
Nongnuch Sutivisedsak, Timothy D Leathers, Neil PJ Price
SpringerPlus.2013;[Epub] CrossRef - Utilization of agricultural biomass in the production of the biopolymer schizophyllan
Nongnuch Sutivisedsak, Timothy D Leathers, Melinda S Nunnally, Neil P J Price, Girma Biresaw
Journal of Industrial Microbiology and Biotechnology.2013; 40(1): 105. CrossRef - Analysis of free amino acids during fermentation by Bacillus subtilis using capillary electrophoresis
Yanli Ren, Jinyan Zhou, Xiaoyong Zhang, Zhidong Li, Juan Zhong, Jie Yang, Tan Xu, Hong Tan
Biotechnology and Bioprocess Engineering.2012; 17(6): 1244. CrossRef
Research Support, Non-U.S. Gov'ts
- Antifungal Activity and Mechanism of Fengycin in the Presence and Absence of Commercial Surfactin Against Rhizopus stolonifer
-
Yang Tao , Xiao-mei Bie , Feng-xia Lv , Hai-zhen Zhao , Zhao-xin Lu
-
J. Microbiol. 2011;49(1):146-150. Published online March 3, 2011
-
DOI: https://doi.org/10.1007/s12275-011-0171-9
-
-
38
View
-
0
Download
-
81
Scopus
-
Abstract
-
The antifungal activity and mechanism of fengycin in the presence and absence of commercial surfactin against Rhizopus stolonifer were investigated. The MIC (minimal inhibitory concentration) of fengycin without commercial surfactin added was 0.4 mg/ml while the MIC of fengycin with commercial surfactin added was 2.0 mg/ml. Fengycin acted on cell membrane and cellular organs and inhibited DNA synthesis. The antifungal effect of fengycin was reduced after commercial surfactin was added. All these results suggest that the fungal cell membrane may be the primary target of fengycin action and commercial surfactin may reduce the antifungal activity of fengycin.
- Isolation and Characterization of Antifungal Peptides Produced by Bacillus amyloliquefaciens LBM5006
-
Lisianne Brittes Benitez , Renata Voltolini Velho , Marcia Pagno Lisboa , Luis Fernando da Costa Medina , Adriano Brandelli
-
J. Microbiol. 2010;48(6):791-797. Published online January 9, 2011
-
DOI: https://doi.org/10.1007/s12275-010-0164-0
-
-
61
View
-
0
Download
-
58
Crossref
-
Abstract
-
Bacillus amyloliquefaciens LBM 5006 produces antagonistic activity against pathogenic bacteria and phytopathogenic fungi, including Aspergillus spp., Fusarium spp., and Bipolaris sorokiniana. PCR analysis revealed the presence of ituD, but not sfp genes, coding for iturin and surfactin, respectively. The antimicrobial substance produced by this strain was isolated by ammonium sulfate precipitation, gel filtration chromatography and 1-butanol extraction. The ultraviolet spectrum was typical of a polypeptide and the infrared spectrum indicates the presence of peptide bonds and acyl group(s). The antimicrobial substance was resistant to proteolytic enzymes and heat treatment, and was reactive with ninhydrin. Mass spectroscopy analysis indicated that B. amyloliquefaciens LBM 5006 produces two antimicrobial peptides, with main peaks at m/z 1,058 Da and 1,464 Da, corresponding to iturin-like and fengycin-like peptides, respectively. B. amyloliquefaciens LBM 5006 showed significant activity against phytopatogenic fungi, showing potential for use as a biocontrol agent or production of antifungal preparations.
-
Citations
Citations to this article as recorded by

- Study on the Inhibitory Effects of Three Endophytic Bacillus Strains on Aspergillus flavus in Maize
Siyu Ma, Min Li, Siqi Zhang, Yin Yang, Fengsha Zhu, Xingyu Li, Shahzad Munir, Pengfei He, Pengbo He, Yixin Wu, Yueqiu He, Ping Tang
Metabolites.2025; 15(4): 268. CrossRef - Culture Optimization of Endophytic and Rhizosphere Bacteria and Exploration of Antifungal Substances
Y. Sheng, X. Li, H. Yang, M. Chu, X. Niu, N. Wang, H. Bao, F. Zhan, R. Yang, K. Lou, Y. Shi, G. Zhang
Applied Biochemistry and Microbiology.2025;[Epub] CrossRef - Enhancing Phosphorus Uptake and Mitigating Lead Stress in Maize Using the Rhizospheric Fungus Talaromyces purpureogenus PH7
Iqbal Hussain, Muhammad Irshad, Anwar Hussain, Muhammad Qadir, Asif Mehmood, Muneeb urrehman, Naeem Khan
CLEAN – Soil, Air, Water.2025;[Epub] CrossRef - Phosphate solubilizing Aspergillus Niger PH1 ameliorates growth and alleviates lead stress in maize through improved photosynthetic and antioxidant response
Iqbal Hussain, Muhammad Irshad, Anwar Hussain, Muhammad Qadir, Asif Mehmood, Muneebur Rahman, Abdulwahed Fahad Alrefaei, Mikhlid H. Almutairi, Sajid Ali, Muhammad Hamayun
BMC Plant Biology.2024;[Epub] CrossRef - Genome analysis of Pseudomonas strain 4B with broad antagonistic activity against toxigenic fungi
Flávio Fonseca Veras, Paolo Stincone, Juliane Elisa Welke, Ana Carolina Ritter, Franciele Maboni Siqueira, Ana Paula Muterle Varela, Fabiana Quoos Mayer, Adriano Brandelli
Brazilian Journal of Microbiology.2024; 55(1): 269. CrossRef - Genomic Insights into the Bactericidal and Fungicidal Potential of Bacillus mycoides b12.3 Isolated in the Soil of Olkhon Island in Lake Baikal, Russia
Maria N. Romanenko, Anton E. Shikov, Iuliia A. Savina, Fedor M. Shmatov, Anton A. Nizhnikov, Kirill S. Antonets
Microorganisms.2024; 12(12): 2450. CrossRef - Antagonistic effects of Bacillus species against bacterial multi-drug resistant (MDR) food-borne pathogens and aflatoxigenic fungi
Temilade Ozabor, Deborah Falomo, Elizabeth Taiwo, Oyindamola Alabi, Precious Adediran, Femi Ayoade, Ilesanmi Fadahunsi, Janet Olaitan
UMYU Journal of Microbiology Research (UJMR).2024; : 89. CrossRef - Evaluation of the mechanism of action of Bacillus spp. to manage Meloidogyne incognita with split root assay, RT-qPCR and qPCR
Kaitlin M. Gattoni, Sang Wook Park, Kathy S. Lawrence
Frontiers in Plant Science.2023;[Epub] CrossRef - Microbial lipopeptides: Properties, mechanics and engineering for novel lipopeptides
Smitha Mony Sreedharan, Niharika Rishi, Rajni Singh
Microbiological Research.2023; 271: 127363. CrossRef - Characterisation and action mode of Gluconacin, a bacteriocin with antimicrobial activity against Xanthomonas albilineans
Elizabeth Teixeira de Almeida Ramos, Carlos Henrique Salvino Gadelha Meneses, Marcia Soares Vidal, José Ivo Baldani
Annals of Applied Biology.2022; 180(1): 163. CrossRef - Isolation and characterization of a new strain of Bacillus amyloliquefaciens and its effect on strawberry preservation
Tingting Ying, Peijun Wu, Linlin Gao, Congcong Wang, Tonghe Zhang, Sisi Liu, Ruqiang Huang
LWT.2022; 165: 113712. CrossRef - Bacillus subtilis strain F62 against Fusarium oxysporum and promoting plant growth in the grapevine rootstock SO4
ALESSANDRA RUSSI, MARCUS ANDRÉ K. ALMANÇA, JOSÉLI SCHWAMBACH
Anais da Academia Brasileira de Ciências.2022;[Epub] CrossRef - Influence of Heat Stress on Poultry Growth Performance, Intestinal Inflammation, and Immune Function and Potential Mitigation by Probiotics
Rafiq Ahmad, Yu-Hsiang Yu, Felix Shih-Hsiang Hsiao, Chin-Hui Su, Hsiu-Chou Liu, Isabel Tobin, Guolong Zhang, Yeong-Hsiang Cheng
Animals.2022; 12(17): 2297. CrossRef - In Vitro and In Vivo Anti-Clostridioides difficile Effect of a Probiotic Bacillus amyloliquefaciens Strain
Md Imtiazul Islam, Hoonhee Seo, Asma Redwan, Sukyung Kim, Saebim Lee, Mashuk Siddiquee, Ho-Yeon Song
Journal of Microbiology and Biotechnology.2022; 32(1): 46. CrossRef - A review on characterization, applications and structure-activity relationships of Bacillus species-produced bacteriocins
Shradha Basi-Chipalu, Pallavi Sthapit, Saphala Dhital
Drug Discoveries & Therapeutics.2022; 16(2): 55. CrossRef - The Effect of Surfactants of Microbial Origin on Phytopathogenic Microorganisms
T.P. Pirog, D.V. Piatetska, H.А. Yarova, G.O. Iutynska
Mikrobiolohichnyi Zhurnal.2021; 83(6): 75. CrossRef - Bacterial and yeast microbial diversity of the ripened traditional middle east surk cheese
Yusuf Esen, Bülent Çetin
International Dairy Journal.2021; 117: 105004. CrossRef - Biocontrol of black foot disease on grapevine rootstocks using Bacillus subtilis strain F62
Alessandra Russi, Marcus André Kurtz Almança, Daniel Santos Grohs, Joséli Schwambach
Tropical Plant Pathology.2020; 45(2): 103. CrossRef - Cell-Free Supernatants of Plant Growth-Promoting Bacteria: A Review of Their Use as Biostimulant and Microbial Biocontrol Agents in Sustainable Agriculture
Marika Pellegrini, Giancarlo Pagnani, Matteo Bernardi, Alessandro Mattedi, Daniela M. Spera, Maddalena Del Gallo
Sustainability.2020; 12(23): 9917. CrossRef - Prebiotic, Probiotic, Antimicrobial, and Functional Food Applications of Bacillus amyloliquefaciens
Kalekristos WoldemariamYohannes, Zhen Wan, Qinglin Yu, Hongyan Li, Xuetuan Wei, Yingli Liu, Jing Wang, Baoguo Sun
Journal of Agricultural and Food Chemistry.2020; 68(50): 14709. CrossRef - The response strategies of Colletotrichum gloeosporioides s.s. due to the stress caused by biological control agent Bacillus amyloliquefaciens deciphered by transcriptome analyses
Qing-Hai Wang, Yan-Ping Ji, Yong-Yun Qu, Yu-Kun Qi, De-Wei Li, Zhen-Yu Liu, Xiao-Qin Wu
Biological Control.2020; 150: 104372. CrossRef - Biocontrol of Fusarium wilt disease in strawberries using bioorganic fertilizer fortified with Bacillus licheniformis X-1 and Bacillus methylotrophicus Z-1
Yan Chen, Yongping Xu, Tong Zhou, Mahinur S. Akkaya, Lili Wang, Shuying Li, Xiaoyu Li
3 Biotech.2020;[Epub] CrossRef -
Antimicrobial
Bacillus velezensis
HC6: production of three kinds of lipopeptides and biocontrol potential in maize
Y. Liu, K. Teng, T. Wang, E. Dong, M. Zhang, Y. Tao, J. Zhong
Journal of Applied Microbiology.2020; 128(1): 242. CrossRef - A novel antimicrobial protein of the endophytic Bacillus amyloliquefaciens and its control effect against Fusarium chlamydosporum
Han-mingyue Zhu, Yuan-zhi Pan
BioControl.2019; 64(6): 737. CrossRef - Antagonist effects of strains of Bacillus spp. against Rhizoctonia solani for their protection against several plant diseases: Alternatives to chemical pesticides
Aqleem Abbas, Shahid Ullah Khan, Wasim Ullah Khan, Tawfik A. Saleh, Muhammad Hafeez Ullah Khan, Sana Ullah, Ahmad Ali, Muhammad Ikram
Comptes Rendus. Biologies.2019; 342(5-6): 124. CrossRef - Phân lập và định danh vi khuẩn nội sinh ở cây diếp cá (Houttuynia cordata Thunb, Saururaceae) tại tỉnh Kiên Giang có hoạt tính kháng khuẩn với vi khuẩn Staphylococcus aureus từ mụn nhọt ở người
Huỳnh Văn Trương, Nguyễn Hữu Hiệp, Lý Tú Hương
Can Tho University Journal of Science.2019; 55(Công ng: 166. CrossRef - Identification of the biocontrol strain LB-2 and determination of its antifungal effects on plant pathogenic fungi
Caiyun Liu, Z. Chang
Journal of Plant Pathology.2018; 100(1): 25. CrossRef - Identification and characterization of a novel antimicrobial peptide compound produced by Bacillus megaterium strain isolated from oral microflora
Abdullah S.A. Al-Thubiani, Yahia A. Maher, Adel Fathi, Mohammed A.S. Abourehab, Mohammed Alarjah, Mohd S.A. Khan, Saleh B. Al- Ghamdi
Saudi Pharmaceutical Journal.2018; 26(8): 1089. CrossRef - Antimicrobial discovery from natural and unusual sources
Salwa Mansur Ali, Ruqaiyyah Siddiqui, Naveed Ahmed Khan
Journal of Pharmacy and Pharmacology.2018; 70(10): 1287. CrossRef -
Bacillus amyloliquefaciens
induces production of a novel blennolide K in coculture of Setophoma terrestris
D. Arora, G. Chashoo, V. Singamaneni, N. Sharma, P. Gupta, S. Jaglan
Journal of Applied Microbiology.2018; 124(3): 730. CrossRef - Identification of a small antimycotic peptide produced by Bacillus amyloliquefaciens 6256
Qing Xia Zhang, Ying Zhang, Ling Ling He, Zhao Lin Ji, Yun Hui Tong
Pesticide Biochemistry and Physiology.2018; 150: 78. CrossRef - Biological control of plant pathogens by Bacillus species
Djordje Fira, Ivica Dimkić, Tanja Berić, Jelena Lozo, Slaviša Stanković
Journal of Biotechnology.2018; 285: 44. CrossRef - Molecular characterization of bmyC gene of the mosquito pupicidal bacteria, Bacillus amyloliquefaciens (VCRC B483) and in silico analysis of bacillomycin D synthetase C protein
Mathivanan Ashokkumar, Geetha Irudayaraj, Nandakumar Yellapu, Arulsamy Mary Manonmani
World Journal of Microbiology and Biotechnology.2018;[Epub] CrossRef - Isolation and identification of antifungal peptides from Bacillus amyloliquefaciens W10
Qing-Xia Zhang, Ying Zhang, Hai-Huan Shan, Yun-Hui Tong, Xi-Jun Chen, Feng-Quan Liu
Environmental Science and Pollution Research.2017; 24(32): 25000. CrossRef - Biological characteristics ofBacillus amyloliquefaciensAK-0 and suppression of ginseng root rot caused byCylindrocarpon destructans
Y.S. Kim, K. Balaraju, Y.H. Jeon
Journal of Applied Microbiology.2017; 122(1): 166. CrossRef - Bacillusspecies as versatile weapons for plant pathogens: a review
Jamil Shafi, Hui Tian, Mingshan Ji
Biotechnology & Biotechnological Equipment.2017; 31(3): 446. CrossRef - Antifungal peptidic compound from the deep-sea bacterium Aneurinibacillus sp. YR247
Atsushi Kurata, Yuto Yamaura, Takumi Tanaka, Chiaki Kato, Kaoru Nakasone, Noriaki Kishimoto
World Journal of Microbiology and Biotechnology.2017;[Epub] CrossRef - Characterization of Lipopeptide Biosurfactants Produced by Bacillus licheniformis MB01 from Marine Sediments
Yulin Chen, Shiliang A. Liu, Haijin Mou, Yunxiao Ma, Meng Li, Xiaoke Hu
Frontiers in Microbiology.2017;[Epub] CrossRef - Identification for the First Time of Cyclo(d-Pro-l-Leu) Produced by Bacillus amyloliquefaciens Y1 as a Nematocide for Control of Meloidogyne incognita
Qaiser Jamal, Jeong-Yong Cho, Jae-Hak Moon, Shahzad Munir, Muhammad Anees, Kil Yong Kim
Molecules.2017; 22(11): 1839. CrossRef - Partial purification and characterization of bacteriocin produced byEnterococcus faecalisDU10 and its probiotic attributes
Venkatesh Perumal, Ayyanna Repally, Ankaiah Dasari, Arul Venkatesan
Preparative Biochemistry & Biotechnology.2016; 46(7): 686. CrossRef - Isolation and anti- Verticillium dahliae activity from Bacillus axarquiensis TUBP1 protein
Hong Zeng, Rong Chen, Xiaoxia Luo, Jun Tian
Process Biochemistry.2016; 51(10): 1691. CrossRef - Towards bacterial lipopeptide products for specific applications — a review of appropriate downstream processing schemes
Vivek Rangarajan, Kim G. Clarke
Process Biochemistry.2016; 51(12): 2176. CrossRef - Complete genome sequence of Bacillus amyloliquefaciens B15 isolated from grape skin, a strain of strong inhibitory activity against fungi
Yinzhuo Yan, Shiyu Liu, Deliang Wang, Jie Xue, Danyang Guo, Xulei Song, Fengjie Zhang, Shihai Huang, Chunguang Luan
Journal of Biotechnology.2016; 228: 28. CrossRef - Inhibition of mycotoxin-producing fungi by Bacillus strains isolated from fish intestines
Flávio Fonseca Veras, Ana Paula Folmer Correa, Juliane Elisa Welke, Adriano Brandelli
International Journal of Food Microbiology.2016; 238: 23. CrossRef - Postharvest decay control of a “long-storage” tomato landrace using different preharvest treatments
R. Carrieri, M. Parisi, F. Di Dato, P. Tarantino, F. De Vita, R. Perreca, R. Riccardi, E. Lahoz
Acta Horticulturae.2016; (1144): 423. CrossRef - Antimicrobial peptides of the genus Bacillus: a new era for antibiotics
Chandra Datta Sumi, Byung Wook Yang, In-Cheol Yeo, Young Tae Hahm
Canadian Journal of Microbiology.2015; 61(2): 93. CrossRef - Characterization of Bacitracin Zinc by Matrix-Assisted Laser Desorption Ionization – Tandem Time-of-Flight Mass Spectrometry
Wen-jie Zhao, Jun-qin Qiao, Qun Song, Hong-zhen Lian
Instrumentation Science & Technology.2015; 43(4): 453. CrossRef - Antagonistic Activities of Novel Peptides from Bacillus amyloliquefaciens PT14 against Fusarium solani and Fusarium oxysporum
Young Gwon Kim, Hee Kyoung Kang, Kee-Deok Kwon, Chang Ho Seo, Hyang Burm Lee, Yoonkyung Park
Journal of Agricultural and Food Chemistry.2015; 63(48): 10380. CrossRef - Structural characterization and temperature-dependent production of C17-fengycin B derived from Bacillus amyloliquefaciens subsp. plantarum BC32-1
Jiyoung Nam, Min Young Jung, Pyoung Il Kim, Hyang Burm Lee, Si Wouk Kim, Chul Won Lee
Biotechnology and Bioprocess Engineering.2015; 20(4): 708. CrossRef - Bacteriocinogenic potential of a probiotic strain Bacillus coagulans [BDU3] from Ngari
Kaja Abdhul, Mohan Ganesh, Santhanam Shanmughapriya, Shanmugam Vanithamani, Murugesan Kanagavel, Kumarasamy Anbarasu, Kalimuthusamy Natarajaseenivasan
International Journal of Biological Macromolecules.2015; 79: 800. CrossRef - Bacillus amyloliquefaciens Q‐426 as a potential biocontrol agent against Fusarium oxysporum f. sp. spinaciae
Pengchao Zhao, Chunshan Quan, Yingguo Wang, Jianhua Wang, Shengdi Fan
Journal of Basic Microbiology.2014; 54(5): 448. CrossRef - Inhibition of conidiophore development in Aspergillus fumigatus by an Escherichia coli DH5α strain, a promising antifungal candidate against aspergillosis
M. Balhara, S. Ruhil, M. Kumar, S. Dhankhar, A.K. Chhillar
Journal de Mycologie Médicale.2014; 24(1): 1. CrossRef -
Bacillus amyloliquefaciens
ssp. plantarum
strains as potential protective starter cultures for the production of Bikalga
, an alkaline fermented food
C.S. Compaoré, D.S. Nielsen, H. Sawadogo-Lingani, T.S. Berner, K.F. Nielsen, D.B. Adimpong, B. Diawara, G.A. Ouédraogo, M. Jakobsen, L. Thorsen
Journal of Applied Microbiology.2013; 115(1): 133. CrossRef - Co-production of surfactin and a novel bacteriocin by Bacillus subtilis subsp. subtilis H4 isolated from Bikalga, an African alkaline Hibiscus sabdariffa seed fermented condiment
Clarisse S. Compaoré, Dennis S. Nielsen, Labia I.I. Ouoba, Torben S. Berner, Kristian F. Nielsen, Hagrétou Sawadogo-Lingani, Bréhima Diawara, Georges A. Ouédraogo, Mogens Jakobsen, Line Thorsen
International Journal of Food Microbiology.2013; 162(3): 297. CrossRef - Isolation and characterization of an antimicrobial substance from Bacillus subtilis BY08 antagonistic to Bacillus cereus and Listeria monocytogenes
Wei-Jie Wu, Seung-Moon Park, Byung-Yong Ahn
Food Science and Biotechnology.2013; 22(2): 433. CrossRef - Control of Listeria monocytogenes on sliced bologna sausage using a novel bacteriocin, amysin, produced by Bacillus amyloliquefaciens isolated from Thai shrimp paste (Kapi)
Siriporn Kaewklom, Saovaluk Lumlert, Wassawan Kraikul, Ratchaneewan Aunpad
Food Control.2013; 32(2): 552. CrossRef - Antimicrobial factor from Bacillus amyloliquefaciens inhibits Paenibacillus larvae, the causative agent of American foulbrood
Lisianne Brittes Benitez, Renata Voltolini Velho, Amanda de Souza da Motta, Jéferson Segalin, Adriano Brandelli
Archives of Microbiology.2012; 194(3): 177. CrossRef - Isolation of Bacillus amyloliquefaciens Strains with Antifungal Activities from Meju
Hwang-A Lee, Jeong-Hwan Kim
Preventive Nutrition and Food Science.2012; 17(1): 64. CrossRef
- Evaluation of Antagonistic Activities of Bacillus subtilis and Bacillus licheniformis Against Wood-Staining Fungi: In Vitro and In Vivo Experiments
-
Natarajan Velmurugan , Mi Sook Choi , Sang-Sub Han , Yang-Soo Lee
-
J. Microbiol. 2009;47(4):385-392. Published online September 9, 2009
-
DOI: https://doi.org/10.1007/s12275-009-0018-9
-
-
51
View
-
0
Download
-
29
Scopus
-
Abstract
-
The antifungal activity of bacterial strains Bacillus subtilis EF 617317 and B. licheniformis EF 617325 was demonstrated against sapstaining fungal cultures Ophiostoma flexuosum, O. tetropii, O. polonicum, and O. ips in both in vitro and in vivo conditions. The crude active supernatant fractions of 7 days old B. subtilis and B. licheniformis cultures inhibited the growth of sapstaining fungi in laboratory experiments. Thermostability and pH stability of crude supernatants were determined by series of experiments. FT-IR analysis was performed to confirm the surface structural groups of lipoproteins present in the crude active supernatant. Partial purification of lipopeptides present in the crude supernatant was done by using Cellulose anion exchange chromatography and followed by Sephadex gel filtration chromatography. Partially purified compounds significantly inhibited the sapstaining fungal growth by in vitro analysis. The lipopeptides responsible for antifungal activity were identified by electrospray ionization mass spectrometry after partial purification by ion exchange and gel filtration chromatography. Four major ion peaks were identified as m/z 1023, 1038, 1060, and 1081 in B. licheniformis and 3 major ion peaks were identified as m/z 1036, 1058, and 1090 in B. subtilis. In conclusion, the partially purified lipopeptides may belong to surfactin and iturin family. In vivo analysis for antifungal activity of lipopeptides on wood was conducted in laboratory. In addition, the potential of extracts for fungal inhibition on surface and internal part of wood samples were analyzed by scanning electron microscopy.