Antibiotic resistance is rapidly spreading among bacteria
such as Staphylococcus aureus, an opportunistic bacterial
pathogen that causes a variety of diseases in humans. For
the last two decades, bacterial multidrug efflux pumps have
drawn attention due to their potential association with clinical
multidrug resistance. Numerous researchers have demonstrated
efflux-mediated resistance in vitro and in vivo
and found novel multidrug transporters using advanced
genomic information about bacteria. This article aims to
provide a concise summary of multidrug efflux pumps and
their important clinical implications, focusing on recent
findings concerning S. aureus efflux pumps.
Citations
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