Journal of Microbiology

The Role of the Hsp100/Clp Family of Proteins in Prokaryotic Development: Peter Zuber; J. Microbiol. 2000;38(4):193-202.

Acid Stress Responses of Salmonella and E. coli : Survival Mechanisms, Regulation, and Implications for Pathogenesis: John W. Foster; J. Microbiol. 2001;39(2):89-94.

Thermostability Mechanisms in Enzymes from Thermotoga neapolitana and Pyrococcus furiosus: Claire Vieille , Dinlaka Sriprapundh , Alexei Savchenko , Suil Kang , Harini Krishnamurthy , J. Gregory Zeikus; J. Microbiol. 2001;39(4):245-249.

Molecular Microbiology of the Oil Field Sulfur Cycle: Gerrit Voordouw; J. Microbiol. 2001;39(4):250-253.

Spindle Checkpoint Control in Budding Yeast: Akio Toh-e , Kazuhide Asakawa , Satoshi Yoshida; J. Microbiol. 2001;39(1):1-10.

Regulation of a Bacterial Aromatic Monooxygenase Pathway in Response to Solvent Exposure: Jerome J. Kukor , Juliana Malinverni; J. Microbiol. 2002;40(4):249-253.

Genetic and Environmental Control of Salmonella Invasion: Craig Altier; J. Microbiol. 2005;43(1):85-92.

Abstract: An early step in the pathogenesis of non-typhoidal Salmonella species is the ability to penetrate the intestinal epithelial monolayer. This process of cell invasion requires the production and transport of secreted effector proteins by a type III secretion apparatus encoded in Salmonella pathogenicity island I (SPI-1). The control of invasion involves a number of genetic regulators and environmental stimuli in complex relationships. SPI-1 itself encodes several transcriptional regulators (HilA, HilD, HilC, and InvF) with overlapping sets of target genes. These regulators are, in turn, controlled by both positive and regulators outside SPI-1, including the two-component regulators BarA/SirA and PhoP/Q, and the csr post-transcriptional control system. Additionally, several environmental conditions are known to regulate invasion, including pH, osmolarity, oxygen tension, bile, Mg^2+ concentration, and short chain fatty acids. This review will discuss the current understanding of invasion control, with emphasis on the interaction of environmental factors with genetic regulators that leads to productive infection.

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