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Emergence of Vancomycin-Intermediate Staphylococcus aureus from Predominant Methicillin-Resistant S. aureus Clones in a Korean Hospital
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Journal Article
Emergence of Vancomycin-Intermediate Staphylococcus aureus from Predominant Methicillin-Resistant S. aureus Clones in a Korean Hospital
Hwa Yun Cha 1, Hyun Ok Kim 1, Jong Sook Jin 2, Je Chul Lee 2
Journal of Microbiology 2010;48(4):533-535
DOI: https://doi.org/10.1007/s12275-010-0062-5
Published online: August 20, 2010
1Health and Environment Institute of Daegu, Daegu 706-706, Republic of Korea, 2Department of Microbiology, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea1Health and Environment Institute of Daegu, Daegu 706-706, Republic of Korea, 2Department of Microbiology, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea
Corresponding author:  Je Chul Lee , Tel: +82-53-420-4844, 
Received: 17 February 2010   • Accepted: 9 April 2010
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Abstract

The genetic and epidemiological features of four vancomycin-intermediate Staphylococcus aureus (VISA) isolates obtained from a Korean hospital were evaluated in this study. The VISA isolates were genotyped as sequence type (ST) 5-staphylococcal cassette chromosome mec (SCCmec) II variant (n=2) and ST239- SCCmec III (n=2), which were derived from the predominant methicillin-resistant S. aureus (MRSA) clones in Korean hospitals. One VISA isolate was acquired during vancomycin treatment, whereas three VISA isolates were obtained from the patients who had not previously been exposed to glycopeptides. As VISA is likely to arise from the predominant MRSA clones and may then possibly spread between patients, the emergence of VISA should be monitored with great care in hospitals.

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    Emergence of Vancomycin-Intermediate Staphylococcus aureus from Predominant Methicillin-Resistant S. aureus Clones in a Korean Hospital
    J. Microbiol. 2010;48(4):533-535.   Published online August 20, 2010
    DOI: https://doi.org/10.1007/s12275-010-0062-5
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