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Production of a monoclonal antibody and ultrastructure of the sporozoite of cryptosporidium parvum
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HOME > J. Microbiol > Volume 34(4); 1996 > Article
Production of a monoclonal antibody and ultrastructure of the sporozoite of cryptosporidium parvum
Choi, Young Sook 1, Lee, Sung Tae 2, Cho, Myung Hwan
Journal of Microbiology 1996;34(4):379-383

Department of Biology, College of Sciences; ¹Department of clinical Pathology; ²Orthopedic Surgery, College of Medicine, Kon-Kuk UniversityDepartment of Biology, College of Sciences; ¹Department of clinical Pathology; ²Orthopedic Surgery, College of Medicine, Kon-Kuk University
Corresponding author:  Cho, Myung Hwan ,
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Cryptosporidium Parvum causes a life-threatening diarrhea in acquired immunodeficiency syndrome (AIDS) patients. The sporozoite stage of C. parvum has been known to be a target in treating cryptosporidiosis in AIDS patients as it is an extracellular stage. A sporozoite was ultrastructurally observed. It has a crescent shape with a rounded posterior end and a tapering body. The compact nucleus was located at the posterior end. A monoclonal antibody was produced, which recognized a 43 kDa of sporozoite antigens in a western blot analysis and showed the surface labeling in immunofluorescence.

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    Production of a monoclonal antibody and ultrastructure of the sporozoite of cryptosporidium parvum
    J. Microbiol. 1996;34(4):379-383.
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