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Antibacterial metabolites from the Actinomycete Streptomyces sp. P294
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HOME > J. Microbiol > Volume 54(2); 2016 > Article
Research Support, Non-U.S. Gov't
Antibacterial metabolites from the Actinomycete Streptomyces sp. P294
Huining Su 1, Hongwei Shao 2, Keqin Zhang 1, Guohong Li 1
Journal of Microbiology 2016;54(2):131-135
DOI: https://doi.org/10.1007/s12275-016-5311-9
Published online: February 2, 2016
1Key Laboratory for Conservation and Utilization of Bio-resource, and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming, 650091, Yunnan, P. R. China, 2Angang General Hospital, Anshan, 114021, P. R. China1Key Laboratory for Conservation and Utilization of Bio-resource, and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming, 650091, Yunnan, P. R. China, 2Angang General Hospital, Anshan, 114021, P. R. China
Corresponding author:  Guohong Li , Tel: +86-871-65033805, 
Received: 18 June 2015   • Revised: 22 December 2015   • Accepted: 23 December 2015
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Abstract

The Actinomycete strain P294 was isolated from soil and identified as Streptomyces sp. based upon the results of 16S rRNA sequence analysis. Three compounds obtained from the solid fermentation products of this strain have been determined by 1D, 2D NMR and HRMS experiments. These compounds include two new compounds angumycinones C (1) and D (2), and the known compound X-14881 E (3). All compounds were assayed for antibacterial and nematicidal activity. The results showed the three compounds had different degrees of inhibitory activity against several target bacteria but no significant toxicity against the nematode Caenorhabditis elegans.

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    Antibacterial metabolites from the Actinomycete Streptomyces sp. P294
    J. Microbiol. 2016;54(2):131-135.   Published online February 2, 2016
    DOI: https://doi.org/10.1007/s12275-016-5311-9
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