¹Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Department of Laboratory Medicine and Chang Gung Immunology Consortium, Chang Gung Memorial hospital, and Research Center for Industry of Human Ecology and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taiwan, R.O.C., ²Department of Laboratory Medicine and Biotechnology, Tzu Chi University, College of Medicine, Hualien, Taiwan, R.O.C., ³Department of Internal Medicine, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan, R.O.C., ⁴Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C., ⁵Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C, ⁶Graduate Institute of Medical Biotechnology and Laboratory Science, College of Medicine, Chang-Gung University and Department of Laboratory Medicine, Chang-Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C., ⁷Department of Internal Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan, R.O.C.¹Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Department of Laboratory Medicine and Chang Gung Immunology Consortium, Chang Gung Memorial hospital, and Research Center for Industry of Human Ecology and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taiwan, R.O.C., ²Department of Laboratory Medicine and Biotechnology, Tzu Chi University, College of Medicine, Hualien, Taiwan, R.O.C., ³Department of Internal Medicine, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan, R.O.C., ⁴Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C., ⁵Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C, ⁶Graduate Institute of Medical Biotechnology and Laboratory Science, College of Medicine, Chang-Gung University and Department of Laboratory Medicine, Chang-Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C., ⁷Department of Internal Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan, R.O.C.

Corresponding author:  Po-Chi Soo , Tel: -, 

Received: 28 April 2016   • Revised: 13 September 2016   • Accepted: 20 September 2016