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HOME > J. Microbiol > Volume 56(10); 2018 > Article
Review
[MINIREVIEW] Progress of analytical tools and techniques for human gut microbiome research
Eun-Ji Song 1,2, Eun-Sook Lee 1, Young-Do Nam 1,2
Journal of Microbiology 2018;56(10):693-705.
DOI: https://doi.org/10.1007/s12275-018-8238-5
Published online: September 28, 2018
1Research Group of Healthcare, Korea Food Research Institute, Wanju 55365, Republic of Korea, 2Department of Food Biotechnology, Korea University of Science and Technology, Daejeon 34113, Republic of Korea1Research Group of Healthcare, Korea Food Research Institute, Wanju 55365, Republic of Korea, 2Department of Food Biotechnology, Korea University of Science and Technology, Daejeon 34113, Republic of Korea
Corresponding author:  Young-Do Nam , Tel: +82-63-2199306;, 
Received: 30 April 2018   • Revised: 7 June 2018   • Accepted: 8 June 2018
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Abstract

Massive DNA sequencing studies have expanded our insights and understanding of the ecological and functional characteristics of the gut microbiome. Advanced sequencing technologies allow us to understand the close association of the gut microbiome with human health and critical illnesses. In the future, analyses of the gut microbiome will provide key information associating with human individual health, which will help provide personalized health care for diseases. Numerous molecular biological analysis tools have been rapidly developed and employed for the gut microbiome researches; however, methodological differences among researchers lead to inconsistent data, limiting extensive share of data. It is therefore very essential to standardize the current
method
ologies and establish appropriate pipelines for human gut microbiome research. Herein, we review the methods and procedures currently available for studying the human gut microbiome, including fecal sample collection, metagenomic DNA extraction, massive DNA sequencing, and data analyses with bioinformatics. We believe that this review will contribute to the progress of gut microbiome research in the clinical and practical aspects of human health.

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    [MINIREVIEW] Progress of analytical tools and techniques for human gut microbiome research
    J. Microbiol. 2018;56(10):693-705.   Published online September 28, 2018
    DOI: https://doi.org/10.1007/s12275-018-8238-5
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