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MINIREVIEW]Phytochemicals for the treatment of COVID-19
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MINIREVIEW]Phytochemicals for the treatment of COVID-19
Erica Españo , Jiyeon Kim , Kiho Lee , Jeong-Ki Kim
Journal of Microbiology 2021;59(11):959-977
DOI: https://doi.org/10.1007/s12275-021-1467-z
Published online: November 1, 2021
Department of Pharmacy, Korea University College of Pharmacy, Sejong 30019, Republic of KoreaDepartment of Pharmacy, Korea University College of Pharmacy, Sejong 30019, Republic of Korea
Corresponding author:  Jeong-Ki Kim ,
Received: 7 September 2021   • Revised: 20 October 2021   • Accepted: 20 October 2021
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The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle.

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    MINIREVIEW]Phytochemicals for the treatment of COVID-19
    J. Microbiol. 2021;59(11):959-977.   Published online November 1, 2021
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