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Characterization of a Streptomycete Isolate Producing the Potent Cytotoxic Substance, Nonadecanoic Acid
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HOME > J. Microbiol > Volume 40(2); 2002 > Article
Characterization of a Streptomycete Isolate Producing the Potent Cytotoxic Substance, Nonadecanoic Acid
Jin-cheol Yoo 1, Ji-Man Han 1, Seung-Kwan Nam 1, Keun-shik Baik , Jung-sun Jo , Chi-nam Seong
Journal of Microbiology 2002;40(2):178-181

Department of Biology, Sunchon National University, Sunchon, 540-742,; 1 Department of Pharmacy, Chosun University, Gwangju, 501-759, KoreaDepartment of Biology, Sunchon National University, Sunchon, 540-742,; 1 Department of Pharmacy, Chosun University, Gwangju, 501-759, Korea
Corresponding author:  Chi-nam Seong , Tel: 82-61-750-3613, 
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Abstract

Streptomycete isolate, strain M0137 showed cytotoxic effect on THP-1 cells. One of the purified substances produced from the strain was identified as nonadecanoic acid. Morphological and physiological properties, phylogenetic analysis, and genomic fingerprinting of strain M0137 were determined. Strain M0137 showed a high similarity with Streptomyces scabiei, phenotypically and phylogenetically. In contrast, genomic fingerprinting and G+C content analysis revealed that strain M0137 could be distinguished from S. scabiei ATCC49173 T . We propose to name strain M0137 as Streptomyces scabiei subsp. chosunensis.

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    Characterization of a Streptomycete Isolate Producing the Potent Cytotoxic Substance, Nonadecanoic Acid
    J. Microbiol. 2002;40(2):178-181.
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