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Research Support, Non-U.S. Gov't
- DD1.5k, the Gene Preferentially Expressed in Bloodstream Isolates of Vancomycin-Resistant Enterococcus faecium
- Seung-Han Kim 1, Dong-Gun Lee 2, Jin-Hong Yoo 2, Su-Mi Choi 2, Jung-Hyun Choi 2, Wan-Shik Shin 2, Kyungwon Lee 3, Dongeun Yong 3, Wee Gyo Lee 4, Byung-S. Youn 5, Moon-Won Kang 2
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Journal of Microbiology 2004;42(2):143-146
1 Clinical Research Institute, and; 2 Department of Internal Medicine, The Catholic University of Korea, Seoul, 150-713, Korea; 3 Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, 120-749, Korea; 4 Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, 442-749, Korea; 5 KOMED Institute for Life Science, Graduate School of Biotechnology, Korea University, Seoul, 136-701, Korea1 Clinical Research Institute, and; 2 Department of Internal Medicine, The Catholic University of Korea, Seoul, 150-713, Korea; 3 Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, 120-749, Korea; 4 Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, 442-749, Korea; 5 KOMED Institute for Life Science, Graduate School of Biotechnology, Korea University, Seoul, 136-701, Korea
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Corresponding author:
Wan-Shik Shin , Tel: 82-2-3779-1151,
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Abstract
Vancomycin-resistant Enterococcus faecium (VREFM) is becoming a threatening pathogen. We identified a gene called DD1.5K by differential display-PCR, which was preferentially expressed in the bloodstream isolates of VREFM. Due to its amino acid similarity to transfer complex protein, trsE, and tissue-specific expression, this gene may be involved in virulence of VREFM.
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