MSK
Search
- Page Path
- HOME > Search
Journal Article
- Impact of feeding regimens on the composition of gut microbiota and metabolite profiles of plasma and feces from Mongolian sheep
- Bohui Wang , Yulong Luo , Rina Su , Duo Yao , Yanru Hou , Chang Liu , Rui Du , Ye Jin
- J. Microbiol. 2020;58(6):472-482. Published online April 22, 2020
- DOI: https://doi.org/10.1007/s12275-020-9501-0
- 66 View
- 0 Download
- 23 Web of Science
- 19 Crossref
-
Abstract
- Mongolian sheep are an indigenous ruminant raised for wool and meat production in China. The gut microbial community plays an important role in animal performance and metabolism. The objective of this study was to investigate the effects of two feeding regimens on the diversity and composition of gut microbiota and metabolite profiles of feces and plasma from Mongolian sheep. A total of 20 Mongolian sheep were assigned to one of two feeding regimens: free grazing (FG) and barn confinement (BC). When samples were collected, the average live weights of the sheep were 31.28 ± 1.56 kg and 34.18 ± 1.87 kg for the FG and BC groups, respectively. At the genus level, the FG group showed higher levels of Bacteroides, RC9_gut_group, Alistipes, Phocaeicola, Barnesiella, and Oscillibacter, and lower levels of Succinivibrio, Treponema, and Prevotella, compared to the BC group. The butyric acid content in feces was lower in the FG group (P < 0.05). Higher levels of palmitic acid, oleic acid, alpha-linolenic acid, L-carnitine, L-citrulline, and L-histidine, and lower levels of L-tyrosine, L-phenylalanine, and L-kynurenine were found in the plasma of the FG sheep. Moreover, there were substantial associations between several gut microbiota genera and alterations in feces and plasma metabolites especially those involved in the metabolism of butyric acid, linolenic acid, and L-tyrosine. Feeding regimens can not only influence the composition of gut microbiota, but also alter metabolic homeostasis in sheep.
-
Citations
Citations to this article as recorded by
- Combined transcriptome and metabolome analysis reveals breed-specific regulatory mechanisms in Dorper and Tan sheep
Yuhao Ma, Ganxian Cai, Jianfei Chen, Xue Yang, Guoying Hua, Deping Han, Xinhai Li, Dengzhen Feng, Xuemei Deng
BMC Genomics.2024;[Epub] CrossRef - Effects of feeding patterns on production performance, lipo-nutritional quality and gut microbiota of Sunit sheep
Letian Kang, Weihao Wang, Le Yang, Ting Liu, Taiwu Zhang, Junkang Xie, Maoqin Zhai, Xin Zhao, Yan Duan, Ye Jin
Meat Science.2024; 218: 109642. CrossRef - Impact of Varying Dietary Calcium Contents on the Gut Metabolomics of Yunnan Semi-Fine Wool Sheep (Ovis aries)
Muhammad Khan, Xiaoqi Zhao, Xiaojun Ni, Sikandar Ali, Baiji Danzeng, Hongyuan Yang, Maida Mushtaq, Jiachong Liang, Bai Xue, Guobo Quan
Metabolites.2024; 14(7): 381. CrossRef - Disrupted Microbiota of Colon Results in Worse Immunity and Metabolism in Low-Birth-Weight Jinhua Newborn Piglets
Jiaheng Li, Zeou Wei, Fangfang Lou, Xiaojun Zhang, Jiujun Duan, Chengzeng Luo, Xujin Hu, Pingguang Tu, Lei Liu, Ruqing Zhong, Liang Chen, Xizhong Du, Hongfu Zhang
Microorganisms.2024; 12(7): 1371. CrossRef - Effect of Feeding System on Muscle Fiber Composition, Antioxidant Capacity, and Nutritional and Organoleptic Traits of Goat Meat
Lu Dou, Ye Jin, Huijiao Li, Chang Liu, Zhihao Yang, Xiaoyu Chen, Lina Sun, Lihua Zhao, Lin Su
Animals.2023; 13(1): 172. CrossRef - Supplemental Clostridium butyricum modulates skeletal muscle development and meat quality by shaping the gut microbiota of lambs
Lu Dou, Chang Liu, Xiaoyu Chen, Zhihao Yang, Guanhua Hu, Min Zhang, Lina Sun, Lin Su, Lihua Zhao, Ye Jin
Meat Science.2023; 204: 109235. CrossRef - Metabolome and microbiome analysis revealed the effect mechanism of different feeding modes on the meat quality of Black Tibetan sheep
Xue Zhang, Lijuan Han, Linsheng Gui, Sayed Haidar Abbas Raza, Shengzhen Hou, Baochun Yang, Zhiyou Wang, Ying Ma, Raafat T. M. Makhlof, Zamzam Alhuwaymil, Samah F. Ibrahim
Frontiers in Microbiology.2023;[Epub] CrossRef - Effect of lactic acid bacteria by different concentrations of copper based on non-target metabolomic analysis
Xinlei Li, Shiyue Chen, Lili Zhao, Xiangpeng Zeng, Yanyan Liu, Chaochuang Li, Qingxiang Yang
Environmental Science and Pollution Research.2023; 30(49): 107568. CrossRef - Responses of rumen microorganisms and metabolites to different roughage of domesticated Tibetan sheep
Yue Ren, Yangzhong Zhaxi, Renzeng Ciwang, Zhengwen Wang, Mengjun Liu
Frontiers in Microbiology.2023;[Epub] CrossRef - Rumen and Fecal Microbiota Characteristics of Qinchuan Cattle with Divergent Residual Feed Intake
Xiaonan Zhou, Ying Ma, Chaoyun Yang, Zhiyan Zhao, Yanling Ding, Yanfeng Zhang, Pengfei Wang, Lei Zhao, Chenglong Li, Zonghua Su, Xiaowei Wang, Wenxun Ming, Ling Zeng, Xiaolong Kang
Microorganisms.2023; 11(2): 358. CrossRef - Repeated use of 3,4-methylenedioxymethamphetamine is associated with the resilience in mice after chronic social defeat stress: A role of gut–microbiota–brain axis
Youge Qu, Akifumi Eguchi, Xiayun Wan, Li Ma, Lijia Chang, Jiajing Shan, Yong Yang, Chisato Mori, Kenji Hashimoto
Psychiatry Research.2023; 320: 115020. CrossRef - Contribution of gut microbiomes and their metabolomes to the performance of Dorper and Tan sheep
Yuhao Ma, Xue Yang, Guoying Hua, Xiaotian Deng, Tianlan Xia, Xinhai Li, Dengzhen Feng, Xuemei Deng
Frontiers in Microbiology.2022;[Epub] CrossRef - Intestinal Microbial Diversity of Free-Range and Captive Yak in Qinghai Province
Ying Wen, Shaofei Li, Zishuo Wang, Hao Feng, Xiaoting Yao, Mingjie Liu, Jianjun Chang, Xiaoyu Ding, Huiying Zhao, Wentao Ma
Microorganisms.2022; 10(4): 754. CrossRef - Bacterial communities in the gastrointestinal tract segments of helminth-resistant and helminth-susceptible sheep
Erwin A. Paz, Eng Guan Chua, Shamshad Ul Hassan, Johan C. Greeff, Dieter G. Palmer, Shimin Liu, Binit Lamichhane, Néstor Sepúlveda, Junhua Liu, Chin Yen Tay, Graeme B. Martin
Animal Microbiome.2022;[Epub] CrossRef - Comparison and analysis on sheep meat quality and flavor under pasture-based fattening contrast to intensive pasture-based feeding system
Zhichao Zhang, Xiaoqi Wang, Yan Jin, Kai Zhao, Ziyuan Duan
Animal Bioscience.2022; 35(7): 1069. CrossRef - Using Untargeted LC-MS Metabolomics to Identify the Association of Biomarkers in Cattle Feces with Marbling Standard Longissimus Lumborum
Dong Chen, Minchao Su, He Zhu, Gang Zhong, Xiaoyan Wang, Weimin Ma, Metha Wanapat, Zhiliang Tan
Animals.2022; 12(17): 2243. CrossRef - Comparative Analysis of the Composition of Fatty Acids and Metabolites between Black Tibetan and Chaka Sheep on the Qinghai—Tibet Plateau
Tongqing Guo, Xungang Wang, Qian Zhang, Lin Wei, Hongjin Liu, Na Zhao, Linyong Hu, Shixiao Xu
Animals.2022; 12(20): 2745. CrossRef - Metabolite Profile of Sheep Serum With High or Low Average Daily Gain
Tao Feng, Hongxiang Ding, Jing Wang, Wei Xu, Yan Liu, Ákos Kenéz
Frontiers in Veterinary Science.2021;[Epub] CrossRef - The gut bacterial diversity of sheep associated with different breeds in Qinghai province
Jianjun Chang, Xiaoting Yao, Chenxiang Zuo, Yuxu Qi, Dekun Chen, Wentao Ma
BMC Veterinary Research.2020;[Epub] CrossRef
- Combined transcriptome and metabolome analysis reveals breed-specific regulatory mechanisms in Dorper and Tan sheep
Research Support, Non-U.S. Gov't
- Potentiation of Bacterial Killing Activity of Zinc Chloride by Pyrrolidine Dithiocarbamate
- Eun-Kyoung Choi , Hye-Hyang Lee , Mi-Sun Kang , Byung-Gook Kim , Hoi-Soon Lim , Seon-Mi Kim , In-Chol Kang
- J. Microbiol. 2010;48(1):40-43. Published online March 11, 2010
- DOI: https://doi.org/10.1007/s12275-009-0049-2
- 61 View
- 0 Download
- 21 Crossref
-
Abstract
- Zinc has antimicrobial activity and zinc salts including zinc chloride (ZnCl2) have been used for the control of oral malodor. In this study, we hypothesized that pyrrolidine dithiocarbamate (PDTC), a zinc ionophore, may enhance antimicrobial efficacy of ZnCl2. The bactericidal effectiveness of ZnCl2 alone (0.5-8 mM) or in combination with PDTC (1 or 10 μM) was evaluated by in vitro short (1 h) time-killing assays against Fusobacterium nucleatum and Porphyromonas gingivalis. Only a slight viability decrease was observed with ZnCl2 or PDTC alone after 1-h incubation. By contrast, combination of ZnCl2 and PDTC could achieve a more than 100-fold viability reduction compared with ZnCl2 or PDTC alone in F. nucleatum and P. gingivalis. Therefore, PDTC greatly enhanced the bactericidal activity of ZnCl2 against the oral malodor-producing bacteria. These results suggest that use of PDTC may be useful for enhancing bactericidal activity of antimalodor regimens of zinc salts.
-
Citations
Citations to this article as recorded by- Synthesis characterization, biocidal, and cytotoxic activities of Mn(II) and Hg(II) bridging complexes.
Vinay Kumar Srivastava, Khushboo Rani
Journal of Sulfur Chemistry.2025; 46(3): 539. CrossRef - Burkholderia sp. EIKU21 mediated synthesis of biogenic ZnO nanoparticle–based pigment for development of antibacterial cotton fabric through nanocoating
Taniya Roy, Nilendu Basak, Shashwata Mainak, Sangita Das, Sk Imran Ali, Ekramul Islam
Biomass Conversion and Biorefinery.2025; 15(5): 6927. CrossRef - Enhanced binding interaction and antibacterial inhibition for nanometal oxide particles activated with Aloe Vulgarize through one-pot ultrasonication techniques
Nur Syafiqah Farhanah Dzulkharnien, Rosiah Rohani, Noorhisham Tan Kofli, Noor Alicezah Mohd Kasim, Suhaila Abd. Muid, Melonney Patrick, Noor Akhmazillah Mohd Fauzi, Hajar Alias, Husna Ahmad Radzuan
Bioorganic Chemistry.2024; 150: 107513. CrossRef - Nano-strategies used for combatting the scourge of tuberculosis infections
Ren Fang, Yubao Jin, Weihao Kong, Hui Wang, Shuxian Wang, Xiaotian Li, Jiayin Xing, Yumiao Zhang, Xingyue Yang, Ningning Song
Discover Immunity.2024;[Epub] CrossRef - A novel activated-zinc antiseptic solution effective against MRSA and Pseudomonas aeruginosa: a pig model
Derek L Hill, Cody Pinger, Erica L Noland, Kevin Morton, Alessandra M Agostinho Hunt, Elizabeth Pensler, Sarah Cantu, Paul S Attar, Ahmed Siddiqi
Journal of Wound Care.2022; 31(Sup7): S41. CrossRef - Zinc ionophores: chemistry and biological applications
Simone Scavo, Valentina Oliveri
Journal of Inorganic Biochemistry.2022; 228: 111691. CrossRef - Contribution of nitrous oxide to the carbon footprint of full-scale wastewater treatment plants and mitigation strategies- a critical review
Hong Yao, Xinyu Gao, Jingbo Guo, Hui Wang, Liang Zhang, Liru Fan, Fangxu Jia, Jianhua Guo, Yongzhen Peng
Environmental Pollution.2022; 314: 120295. CrossRef - Comparative study of the effects of ziram and disulfiram on human monocyte-derived macrophage functions and polarization: involvement of zinc
Melissa Parny, José Bernad, Mélissa Prat, Marie Salon, Agnès Aubouy, Elsa Bonnafé, Agnès Coste, Bernard Pipy, Michel Treilhou
Cell Biology and Toxicology.2021; 37(3): 379. CrossRef - Insights into the Antimicrobial Potential of Dithiocarbamate Anions and Metal-Based Species
Chien Ing Yeo, Edward R. T. Tiekink, Jactty Chew
Inorganics.2021; 9(6): 48. CrossRef - Dithiocarbamate Complexes of Platinum Group Metals: Structural Aspects and Applications
Yee Seng Tan, Chien Ing Yeo, Edward R. T. Tiekink, Peter J. Heard
Inorganics.2021; 9(8): 60. CrossRef - Atovaquone and Berberine Chloride Reduce SARS-CoV-2 Replication In Vitro
Bruno A. Rodriguez-Rodriguez, Maria G. Noval, Maria E. Kaczmarek, Kyung Ku Jang, Sara A. Thannickal, Angelica Cifuentes Kottkamp, Rebecca S. Brown, Margaret Kielian, Ken Cadwell, Kenneth A. Stapleford
Viruses.2021; 13(12): 2437. CrossRef - Fusobacterium nucleatum – Friend or foe?
Kamila Stokowa-Sołtys, Kamil Wojtkowiak, Karolina Jagiełło
Journal of Inorganic Biochemistry.2021; 224: 111586. CrossRef - Fabrication of palladium nanoparticles anchored polypyrrole functionalized reduced graphene oxide nanocomposite for antibiofilm associated orthopedic tissue engineering
Balaji Murugesan, Nithya Pandiyan, Mayakrishnan Arumugam, Jegatheeswaran Sonamuthu, Selvam Samayanan, Cai Yurong, Yao Juming, Sundrarajan Mahalingam
Applied Surface Science.2020; 510: 145403. CrossRef Enhancing ZnO-NP Antibacterial and Osteogenesis Properties in Orthopedic Applications: A Review
Yuehong Li, Yue Yang, Yun'an Qing, Ruiyan Li, Xiongfeng Tang, Deming Guo, Yanguo Qin
International Journal of Nanomedicine.2020; Volume 15: 6247. CrossRef- [BMIM] PF6 ionic liquid mediated green synthesis of ceramic SrO/CeO2 nanostructure using Pedalium murex leaf extract and their antioxidant and antibacterial activities
Nithya Pandiyan, Balaji Murugesan, Jegatheeswaran Sonamuthu, Selvam Samayanan, Sundrarajan Mahalingam
Ceramics International.2019; 45(9): 12138. CrossRef - Zinc‐oxide nanoparticles act catalytically and synergistically with nitric oxide donors to enhance antimicrobial efficacy
Priyadarshini Singha, Christina D. Workman, Jitendra Pant, Sean P. Hopkins, Hitesh Handa
Journal of Biomedical Materials Research Part A.2019; 107(7): 1425. CrossRef - Mechanistic study on antibacterial action of zinc oxide nanoparticles synthesized using green route
Happy Agarwal, Soumya Menon, S. Venkat Kumar, S. Rajeshkumar
Chemico-Biological Interactions.2018; 286: 60. CrossRef - Use of carbon monoxide and hydrogen by a bacteria–animal symbiosis from seagrass sediments
Manuel Kleiner, Cecilia Wentrup, Thomas Holler, Gaute Lavik, Jens Harder, Christian Lott, Sten Littmann, Marcel M. M. Kuypers, Nicole Dubilier
Environmental Microbiology.2015; 17(12): 5023. CrossRef - Cetylpyridinium chloride suppresses gene expression associated with halitosis
J. Liu, J.-Q. Ling, C.D. Wu
Archives of Oral Biology.2013; 58(11): 1686. CrossRef - Structure and coordination in mono and dinuclear Zn(II)-pyrrolidine dithiocarbamate complexes
Deepanwita Ghosh, Kaushik Sen, Abhijit K. Das
Structural Chemistry.2012; 23(1): 227. CrossRef - Synthesis and characterization of mixed ligand complexes of lomefloxacin drug and glycine with transition metals. Antibacterial, antifungal and cytotoxicity studies
Gehad G. Mohamed, Hanan F. Abd El-Halim, Maher M.I. El-Dessouky, Walaa H. Mahmoud
Journal of Molecular Structure.2011; 999(1-3): 29. CrossRef
- Synthesis characterization, biocidal, and cytotoxic activities of Mn(II) and Hg(II) bridging complexes.
First
Prev
TOP
