Research Support, Non-U.S. Gov't
- EDITORIAL] Human fungal pathogens: Why should we learn?
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Jeong-Yoon Kim
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J. Microbiol. 2016;54(3):145-148.
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DOI: https://doi.org/10.1007/s12275-016-0647-8
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Abstract
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Human fungal pathogens that cause invasive infections are
hidden killers, taking lives of one and a half million people
every year. However, research progress in this field has not
been rapid enough to effectively prevent or treat life-threatening
fungal diseases. To update recent research progress
and promote more active research in the field of human fungal
pathogens, eleven review articles concerning the virulence
mechanisms and host interactions of four major human fungal
pathogens–Candida albicans, Cryptococcus neoformans,
Aspergillus fumigatus, and Histoplasma capsulatum–are
presented in this special issue.
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Citations
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Frontiers in Immunology.2023;[Epub] CrossRef - Betulinic acid and Drummondin E: Potential inhibitors of Unfolded Protein Response Pathway of Candida auris
Nahid Akhtar, Amit Joshi, Vikas Kaushik, Sangeetha Mohan, M. Amin-ul Mannan
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International Journal of Surgery Case Reports.2022; 93: 106920. CrossRef - Oral delivery of butoconazole nitrate nanoparticles for systemic treatment of chronic paracoccidioidomycosis: A future aspect
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Journal of Inorganic Biochemistry.2021; 225: 111620. CrossRef - Fatty acid dioxygenase-cytochrome P450 fusion enzymes of filamentous fungal pathogens
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Fungal Genetics and Biology.2021; 157: 103623. CrossRef - Membrane-Interacting Antifungal Peptides
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Pathogens.2021; 10(10): 1303. CrossRef - Cathelicidin-inspired antimicrobial peptides as novel antifungal compounds
Martin van Eijk, Stephanie Boerefijn, Lida Cen, Marisela Rosa, Marnix J H Morren, Cornelis K van der Ent, Bart Kraak, Jan Dijksterhuis, Ivan D Valdes, Henk P Haagsman, Hans de Cock
Medical Mycology.2020; 58(8): 1073. CrossRef - Broad-Spectrum Antimicrobial and Antibiofilm Activity of a Natural Clay Mineral from British Columbia, Canada
Shekooh Behroozian, Sarah L. Svensson, Loretta Y. Li, Julian E. Davies, Pascale F. Cossart
mBio.2020;[Epub] CrossRef - Antimicrobial host defence peptides: functions and clinical potential
Neeloffer Mookherjee, Marilyn A. Anderson, Henk P. Haagsman, Donald J. Davidson
Nature Reviews Drug Discovery.2020; 19(5): 311. CrossRef - Alteration of Fermentative Metabolism Enhances Mucor circinelloides Virulence
Sharel P. Díaz-Pérez, J. Alberto Patiño-Medina, Marco I. Valle-Maldonado, Adolfo López-Torres, Irvin E. Jácome-Galarza, Verónica Anaya-Martínez, Verónica Gómez-Ruiz, Jesús Campos-García, Rosa E. Nuñez-Anita, Rafael Ortiz-Alvarado, Martha I. Ramírez-Díaz,
Infection and Immunity.2020;[Epub] CrossRef - Fungal evolution: major ecological adaptations and evolutionary transitions
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Biological Reviews.2019; 94(4): 1443. CrossRef -
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Nathália L S O Malacco, Jéssica A M Souza, Aline C Mendes, Milene A Rachid, Lucas R Kraemer, Matheus S Mattos, Graziele N Lima, Lirlândia P Sousa, Daniele G Souza, Vanessa Pinho, Mauro M Teixeira, Remo C Russo, Frederico M Soriani
Future Microbiology.2019; 14(17): 1511. CrossRef - Aspergillus fumigatus phosphoethanolamine transferase gene gpi7 is required for proper transportation of the cell wall GPI-anchored proteins and polarized growth
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Benjamin J. Wainwright, Andrew G. Bauman, Geoffrey L. Zahn, Peter A. Todd, Danwei Huang
Marine Biodiversity.2019; 49(6): 2601. CrossRef - Glycobiology of Human Fungal Pathogens: New Avenues for Drug Development
Danielle J. Lee, Holly O’Donnell, Françoise H. Routier, Joe Tiralongo, Thomas Haselhorst
Cells.2019; 8(11): 1348. CrossRef - Fungal dissemination is limited by liver macrophage filtration of the blood
Donglei Sun, Peng Sun, Hongmei Li, Mingshun Zhang, Gongguan Liu, Ashley B. Strickland, Yanli Chen, Yong Fu, Juan Xu, Mohammed Yosri, Yuchen Nan, Hong Zhou, Xiquan Zhang, Meiqing Shi
Nature Communications.2019;[Epub] CrossRef - Intracellular cAMP Measurements in Candida albicans Biofilms
Liuliu Jiang, Shengyan Chen, Kairui Sun, Peng Zhou, Xin Wei
BIO-PROTOCOL.2019;[Epub] CrossRef - Linolenic Acid-Modified MPEG-PEI Micelles for Encapsulation of Amphotericin B
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Future Medicinal Chemistry.2019; 11(20): 2647. CrossRef - Design, synthesis, and evaluation of novel 2-substituted 1,4-benzenediol library as antimicrobial agents against clinically relevant pathogens
Daiane Flores Dalla Lana, Bruna Gerardon Batista, Gabriella da Rosa Machado, Mário Lettieri Teixeira, Luís Flávio Souza de Oliveira, Michel Mansur Machado, Saulo Fernandes de Andrade, William Lopes, Marilene Henning Vainstein, Alejandro Peixoto de Abreu L
Saudi Pharmaceutical Journal.2019; 27(8): 1064. CrossRef - Vesicular nanocarrier based treatment of skin fungal infections: Potential and emerging trends in nanoscale pharmacotherapy
Shivani Verma, Puneet Utreja
Asian Journal of Pharmaceutical Sciences.2019; 14(2): 117. CrossRef - Comparison of Two Molecular Assays for Detection and Characterization of Aspergillus fumigatus Triazole Resistance and Cyp51A Mutations in Clinical Isolates and Primary Clinical Samples of Immunocompromised Patients
Patricia Postina, Julian Skladny, Tobias Boch, Oliver A. Cornely, Axel Hamprecht, Peter-Michael Rath, Jörg Steinmann, Oliver Bader, Thomas Miethke, Anne Dietz, Natalia Merker, Wolf-Karsten Hofmann, Dieter Buchheidt, Birgit Spiess
Frontiers in Microbiology.2018;[Epub] CrossRef - Cryptic Aspergillus from clinical samples in the USA and description of a new species in section Flavipedes
João P. Z. Siqueira, Nathan Wiederhold, Josepa Gené, Dania García, Margarete T. G. Almeida, Josep Guarro
Mycoses.2018; 61(11): 814. CrossRef - Pathogen-derived extracellular vesicles mediate virulence in the fatal human pathogen Cryptococcus gattii
Ewa Bielska, Marta Arch Sisquella, Maha Aldeieg, Charlotte Birch, Eloise J. O’Donoghue, Robin C. May
Nature Communications.2018;[Epub] CrossRef - Fungi-Induced Upper and Lower Respiratory Tract Allergic Diseases: One Entity
Aleksandra Barac, David S. Y. Ong, Ljiljana Jovancevic, Aleksandar Peric, Pavol Surda, Vesna Tomic Spiric, Salvatore Rubino
Frontiers in Microbiology.2018;[Epub] CrossRef - Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity
Dayanira Alsina‐Beauchamp, Alejandra Escós, Pilar Fajardo, Diego González‐Romero, Ester Díaz‐Mora, Ana Risco, Miguel A Martín‐Serrano, Carlos del Fresno, Jorge Dominguez‐Andrés, Noelia Aparicio, Rafal Zur, Natalia Shpiro, Gordon D Brown, Carlos Ardavín, M
EMBO Molecular Medicine.2018;[Epub] CrossRef - The Interaction of Human Pathogenic Fungi With C-Type Lectin Receptors
Surabhi Goyal, Juan Camilo Castrillón-Betancur, Esther Klaile, Hortense Slevogt
Frontiers in Immunology.2018;[Epub] CrossRef - JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression
Xueqiang Zhao, Yahui Guo, Changying Jiang, Qing Chang, Shilei Zhang, Tianming Luo, Bin Zhang, Xinming Jia, Mien-Chie Hung, Chen Dong, Xin Lin
Nature Medicine.2017; 23(3): 337. CrossRef - Identification of Fungal Species in Brain Tissue from Alzheimer’s Disease by Next-Generation Sequencing
Ruth Alonso, Diana Pisa, Begoña Aguado, Luis Carrasco
Journal of Alzheimer's Disease.2017; 58(1): 55. CrossRef - Nanoparticles as safe and effective delivery systems of antifungal agents: Achievements and challenges
Ghareb M. Soliman
International Journal of Pharmaceutics.2017; 523(1): 15. CrossRef - Conclusion and future perspectives on antifungal stewardship
Jose María Aguado, Jose Tiago Silva, Emilio Bouza
Journal of Antimicrobial Chemotherapy.2016; 71(suppl 2): ii43. CrossRef