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Research Support, Non-U.S. Gov't
- Optimal Fermentation Conditions for Enhanced Glutathione Production by Saccharomyces cerevisiae FF-8
- Jae-Young Cha , Jin-Chul Park , Beong-Sam Jeon , Young-Choon Lee , Young-Su Cho
- J. Microbiol. 2004;42(1):51-55.
- DOI: https://doi.org/2000 [pii]
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Abstract
- The influence of feedstock amino acids, salt, carbon and nitrogen sources on glutathione production by Saccharomyces cerevisiae FF-8 was investigated. Glucose, yeast extract, KH_2PO_4, and L-cysteine were found to be suitable feedstock. Highest glutathione production was obtained after cultivation with shaking for 72 h in a medium containing glucose 3.0% (w/v), yeast extract 3.0%, KH_2PO_4 0.06% and L-cysteine 0.06%. The glutathione concentration achieved using this medium increased 2.27-fold to 204 mg/l compared to YM basal medium.
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