SARS-CoV-2, the causative agent of COVID-19, first emerged
in 2019. Antibody responses against SARS-CoV-2 have been
given a lot of attention. However, the armamentarium of humoral
and T cells may have differing roles in different viral
infections. Though the exact role of T cells in COVID-19 remains
to be elucidated, prior experience with human coronavirus
has revealed an essential role of T cells in the outcomes
of viral infections. Moreover, an increasing body of evidence
suggests that T cells might be effective against SARS-CoV-2.
This review summarizes the role of T cells in mouse CoV,
human pathogenic respiratory CoV in general and SARSCoV-
2 in specific.
Citations
Citations to this article as recorded by
Vaccine Strategies Against RNA Viruses: Current Advances and Future Directions Kuei-Ching Hsiung, Huan-Jung Chiang, Sebastian Reinig, Shin-Ru Shih Vaccines.2024; 12(12): 1345. CrossRef
Safety and efficacy of COVID-19 vaccine immunization during pregnancy in 1024 pregnant women infected with the SARS-CoV-2 Omicron virus in Shanghai, China Hongmei Deng, Yinpeng Jin, Minmin Sheng, Min Liu, Jie Shen, Wei Qian, Gang Zou, Yixin Liao, Tiefu Liu, Yun Ling, Xiaohong Fan Frontiers in Immunology.2024;[Epub] CrossRef
Differential Impact of Spike Protein Mutations on SARS-CoV-2 Infectivity and Immune Evasion: Insights from Delta and Kappa Variants Tae-Hun Kim, Sojung Bae, Jinjong Myoung Journal of Microbiology and Biotechnology.2024; 34(12): 2506. CrossRef
Animal models for COVID-19 and tuberculosis Björn Corleis, Max Bastian, Donata Hoffmann, Martin Beer, Anca Dorhoi Frontiers in Immunology.2023;[Epub] CrossRef
A mathematical model and simulation scenarios for T and B cells immune response to severe acute respiratory syndrome-coronavirus-2 L Cuesta-Herrera, F Córdova-Lepe, L Pastenes, A D Arencibia, Y Baldera-Moreno, H A Torres-Mantilla Journal of Physics: Conference Series.2023; 2516(1): 012007. CrossRef
Distinctive Combinations of RBD Mutations Contribute to Antibody Evasion in the Case of the SARS-CoV-2 Beta Variant Tae-Hun Kim, Sojung Bae, Sunggeun Goo, Jinjong Myoung Journal of Microbiology and Biotechnology.2023; 33(12): 1587. CrossRef
Two years of COVID-19 pandemic: where are we now? Jinjong Myoung Journal of Microbiology.2022; 60(3): 235. CrossRef
Escape and Over-Activation of Innate Immune Responses by SARS-CoV-2: Two Faces of a Coin Sameer-ul-Salam Mattoo, Seong-Jun Kim, Dae-Gyun Ahn, Jinjong Myoung Viruses.2022; 14(3): 530. CrossRef
Development of a T Cell-Based COVID-19 Vaccine Using a Live Attenuated Influenza Vaccine Viral Vector Irina Isakova-Sivak, Ekaterina Stepanova, Victoria Matyushenko, Sergei Niskanen, Daria Mezhenskaya, Ekaterina Bazhenova, Elena Krutikova, Tatiana Kotomina, Polina Prokopenko, Bogdan Neterebskii, Aleksandr Doronin, Elena Vinogradova, Kirill Yakovlev, Konst Vaccines.2022; 10(7): 1142. CrossRef