Journal of Microbiology

Journal Article

Description of Streptococcus dentalis sp. nov., Streptococcus gingivalis sp. nov., and Streptococcus lingualis sp. nov., Isolated from Human Oral Cavities: Beom-Jin Goo, Young-Sik Choi, Do-Hun Gim, Su-Won Jeong, Jee-Won Choi, Hojun Sung, Jae-Yun Lee, Jin-Woo Bae; J. Microbiol. 2024;62(11):973-983. Published online November 12, 2024; DOI: https://doi.org/10.1007/s12275-024-00178-1

40 View
0 Download

Abstract: We isolated three novel strains, S1^T, S2^T, and S5^T, from human oral cavities and identified them as distinct novel species. All these strains are facultatively anaerobic, Gram-stain-positive, and non-flagellated bacteria. Their optimal growth conditions for these strains were observed in Columbia broth (CB) at 37 °C, pH 7.0, and in the absence of NaCl. Phylogenetic analyses, employing the 16S rRNA gene and whole-genome sequencing, confirmed that all three strains belong to the genus Streptococcus. The 16S rRNA gene sequences of strains S1^T, S2^T, and S5^T showed the highest similarities to Streptococcus parasanguinis, 98.57%, 99.05%, and 99.05%, respectively, and the orthologous average nucleotide identity (OrthoANI) values between the three strains and S. parasanguinis were 93.82%, 93.67%, and 94.04%, respectively. The pairwise OrthoANI values between the novel strains were 94.37% (S1^T-S2^T), 95.03% (S2^T-S5^T), and 94.71% (S1^T-S5^T). All strains had C_20:1 ω9c and summed feature 8 (C_18:1 ω7c and/or C_18:1 ω6c) as major cellular fatty acids. Additionally, diphosphatidylglycerol (DPG) and hydroxyphosphatidylethanolamine (OH-PE) were identified as major polar lipids. Menaquinone was undetected in all strains. The results from the phylogenetic, phenotypic, chemotaxonomic, and genotypic analyses collectively indicated that strains S1^T, S2^T, and S5^T represent three distinct novel species within the genus Streptococcus, and we propose the names Streptococcus dentalis sp. nov. for strain S1^T (= KCTC 21234^T = JCM 36526^T), Streptococcus gingivalis sp. nov. for strain S2^T (= KCTC 21235^T = JCM 36527^T), and Streptococcus lingualis sp. nov. for strain S5^T (= KCTC 21236^T = JCM 36528^T).

Review

The Microbiome Matters: Its Impact on Cancer Development and Therapeutic Responses: In‑Young Chung, Jihyun Kim, Ara Koh; J. Microbiol. 2024;62(3):137-152. Published online April 8, 2024; DOI: https://doi.org/10.1007/s12275-024-00110-7

75 View
4 Download
2 Web of Science
4 Crossref

In the evolving landscape of cancer research, the human microbiome emerges as a pivotal determinant reshaping our understanding of tumorigenesis and therapeutic responses. Advanced sequencing technologies have uncovered a vibrant microbial community not confned to the gut but thriving within tumor tissues. Comprising bacteria, viruses, and fungi, this diverse microbiota displays distinct signatures across various cancers, with most research primarily focusing on bacteria. The correlations between specifc microbial taxa within diferent cancer types underscore their pivotal roles in driving tumorigenesis and infuencing therapeutic responses, particularly in chemotherapy and immunotherapy. This review amalgamates recent discoveries, emphasizing the translocation of the oral microbiome to the gut as a potential marker for microbiome dysbiosis across diverse cancer types and delves into potential mechanisms contributing to cancer promotion. Furthermore, it highlights the adverse efects of the microbiome on cancer development while exploring its potential in fortifying strategies for cancer prevention and treatment.

Citations

Citations to this article as recorded by

COVID-19, Long COVID, and Gastrointestinal Neoplasms: Exploring the Impact of Gut Microbiota and Oncogenic Interactions
do Rêgo Amália Cinthia Meneses, Araújo-Filho Irami
Archives of Cancer Science and Therapy.2024; 8(1): 054. CrossRef
Glycans in the oral bacteria and fungi: Shaping host-microbe interactions and human health
Xiameng Ren, Min Wang, Jiabao Du, Yu Dai, Liuyi Dang, Zheng Li, Jian Shu
International Journal of Biological Macromolecules.2024; 282: 136932. CrossRef
A Review of the Relationship between Tumors of the Biliary System and Intestinal Microorganisms
勇利李
Advances in Clinical Medicine.2024; 14(07): 833. CrossRef
Host-Associated Microbiome
Woo Jun Sul
Journal of Microbiology.2024; 62(3): 135. CrossRef

First
Prev
Page of 1
Next
Last

Search