Salmonella enterica serovar Typhimurium produces many
virulence proteins to cause diseases. The Salmonella MgtC
protein is one of such virulence proteins specially required
for intracellular proliferation inside macrophages and mouse
virulence. In this review, we will cover how the mgtC gene
is turned on or off and what the signals required for mgtC
expression are. Later in this review, we will discuss a recent
understanding of MgtC function in Salmonella pathogenesis
by identifying its target proteins.
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A
trans
-acting leader RNA from a
Salmonella
virulence gene
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