Research Support, Non-U.S. Gov'ts
- Benzaldehyde as an insecticidal, antimicrobial, and antioxidant compound produced by Photorhabdus temperata M1021
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Ihsan Ullah , Abdul Latif Khan , Liaqat Ali , Abdur Rahim Khan , Muhammad Waqas , Javid Hussain , In-Jung Lee , Jae-Ho Shin
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J. Microbiol. 2015;53(2):127-133. Published online January 28, 2015
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DOI: https://doi.org/10.1007/s12275-015-4632-4
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Abstract
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The Photorhabdus temperata M1021 secretes toxic compounds
that kill their insect hosts by arresting immune
responses. Present study was aimed to purify the insecticidal
and antimicrobial compound(s) from the culture extract of
P. temperata M1021 through bioassay guided fractionation.
An ethyl acetate (EtOAc) extract of the P. temperata M1021
exhibited 100% mortality in Galleria mellonella larvae within
72 h. In addition, EtOAc extract and bioactive compound 1
purified form the extract through to column chromatography,
showed phenol oxidase inhibition up to 60% and
80% respectively. The analysis of 1H and 13C NMR spectra
revealed the identity of pure compound as "benzaldehyde".
The benzaldehyde showed insecticidal activity against G.
mellonella in a dose-dependent manner and 100% insect
mortality was observed at 108 h after injection of 8 mM
benzaldehyde. In a PO inhibition assay, 4, 6, and 8 mM concentrations
of benzaldehyde were found to inhibit PO activity
about 15%, 42%, and 80% respectively. In addition,
nodule formation was significantly (P < 0.05) inhibited by 4,
6, and 8 mM of benzaldehyde as compare to control. Moreover,
benzaldehyde was found to have great antioxidant activity
and maximum antioxidant activity was 52.9% at 8 mM
benzaldehyde as compare to control. Antimicrobial activity
was assessed by MIC values ranged from 6 mM 10 mM for
bacterial strains and 8 mM to 10 mM for fungal strains. The
results
suggest that benzaldehyde could be applicable for
developing novel insecticide for agriculture use.
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Chemical Reviews.2020; 120(24): 13273. CrossRef - Activity of papaya seeds (Carica papaya) against Meloidogyne incognita as a soil biofumigant
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BioControl.2019; 64(5): 595. CrossRef - Effects of the Botanical Compound p-Anisaldehyde on Horn Fly (Diptera: Muscidae) Repellency, Mortality, and Reproduction
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Archives of Phytopathology and Plant Protection.2018; 51(13-14): 729. CrossRef - Valorisation of olive agro-industrial by-products as a source of bioactive compounds
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Science of The Total Environment.2018; 645: 533. CrossRef - Secondary Metabolites Produced by Heterorhabditis Symbionts and Their Application in Agriculture: What We Know and What to Do Next
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Journal of Nematology.2017; 49(4): 373. CrossRef - Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights
J. Masschelein, M. Jenner, G. L. Challis
Natural Product Reports.2017; 34(7): 712. CrossRef - Changes in antioxidant activities and volatile compounds of mixed berry juice through fermentation by lactic acid bacteria
Jae-Bum Park, Seung-Hee Lim, Hyun-Su Sim, Joong-Hee Park, Hun-Joo Kwon, Hee Sop Nam, Myoung-Dong Kim, Hyung-Hee Baek, Suk-Jin Ha
Food Science and Biotechnology.2017; 26(2): 441. CrossRef - Antimicrobial efficacy of Cinnamomum javanicum plant extract against Listeria monocytogenes and its application potential with smoked salmon
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Molecules.2017; 22(12): 2223. CrossRef - Metabolites profiling reveals for antimicrobial compositional differences and action mechanism in the toothbrushing stick “miswak” Salvadora persica
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KSBB Journal.2015; 30(3): 132. CrossRef
- In Vitro Antiviral Activity of Red Alga, Polysiphonia morrowii Extract and Its Bromophenols Against Fish Pathogenic Infectious Hematopoietic Necrosis Virus and Infectious Pancreatic Necrosis Virus
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Su-Yeun Kim , Seok Ryel Kim# , Myung-Joo Oh , Sung-Ju Jung , So Young Kang
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J. Microbiol. 2011;49(1):102-106. Published online March 3, 2011
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DOI: https://doi.org/10.1007/s12275-011-1035-z
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Abstract
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Our previous investigation revealed that 80% methanolic extract of the red alga Polysiphonia morrowii has significant antiviral activities against fish pathogenic viruses, infectious hematopoietic necrosis virus (IHNV) and infectious pancreatic necrosis virus (IPNV). The present study was conducted to identify compounds
attributed for its antiviral activities and investigate their antiviral activities against IHNV and IPNV. Activityguided fractionation for 80% methanolic extract of Polysiphonia morrowii using a cell-based assay measuring virus-induced cytopathic effect (CPE) on cells yielded a 90% methanolic fraction, which showed the highest antiviral activity against both viruses among fractions yielded from the extract. From the fraction, two bromophenols were isolated and identified as 3-bromo-4,5-dihydroxybenzyl methyl ether (1) and 3-bromo-4,5-dihydroxybenzaldehyde (2) based on spectroscopic analyses. For both compounds, the concentrations to inhibit 50% of flounder spleen cell (FSP cell) proliferation (CC50) and each viral replication (EC50) were measured. In the pretreatment test, 3-bromo-4,5-dihydroxybenzyl methyl ether (1) and 3-bromo-4,5-dihydroxybenzaldehyde
(2) exhibited significant antiviral activities showing selective index values (SI = CC50/EC50) of 20 to 42 against both IHNV and IPNV. In direct virucidal test, 3-bromo-4,5-dihydroxybenzyl methyl ether (1) showed significant antiviral activites against both viruses while 3-bromo-4,5-dihydroxybenzaldehyde (2) was significantly effective against only IHNV. Although antiviral efficacies of both compounds against
IHNV and IPNV were lower than those of ribavirin used as a positive control, our findings suggested that the red alga Polysiphonia morrowii and isolated two bromophenols may have potential as a therapeutic agent against fish viral diseases.
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Citations
Citations to this article as recorded by

- Study on the immune enhancers against Micropterus salmoides rhabdovirus infection
Ning Lei, Chaonan Zhang, Yanchao Wang, Junjie Zhu
Journal of Limnology.2024;[Epub] CrossRef - The antiviral activity of currently used medicinal plants in aquaculture and structure–activity relationship of their active ingredients
Yang Hu, Xu Zhang, Li‐peng Shan, Lei Liu, Jiong Chen
Reviews in Aquaculture.2024; 16(1): 154. CrossRef - Metabolite Profiling of Macroalgae: Biosynthesis and Beneficial Biological Properties of Active Compounds
Maria Carpena, Cláudia S. G. P. Pereira, Aurora Silva, Paula Barciela, A. Olivia S. Jorge, Ana Perez-Vazquez, Antia G. Pereira, João C. M. Barreira, M. Beatriz P. P. Oliveira, Miguel A. Prieto
Marine Drugs.2024; 22(10): 478. CrossRef - Comprehensive Exploration of Bromophenol Derivatives: Promising Antibacterial Agents against SA and MRSA
Ta Ngoc Ly, Le My Lan, Ming-Yu Tsai, Yun-Wen Chen, Hsin-Yi Hung
ACS Omega.2024; 9(39): 40897. CrossRef - Chemical analysis of marine microdebris pollution in macroalgae from the coastal areas of Argentina
A.D. Forero-López, A.M. Poza, C.V. Colombo, N.G. Morales-Pontet, G.N. Rimondino, M.A. Toniolo, F.E. Malanca, S.E. Botté
Science of The Total Environment.2024; 923: 171390. CrossRef - 3-Bromo-4,5-dihydroxybenzaldehyde Protects Keratinocytes from Particulate Matter 2.5-Induced Damages
Ao-Xuan Zhen, Mei-Jing Piao, Kyoung-Ah Kang, Pincha-Devage-Sameera-Madushan Fernando, Herath-Mudiyanselage-Udari-Lakmini Herath, Suk-Ju Cho, Jin-Won Hyun
Antioxidants.2023; 12(6): 1307. CrossRef - Review on the Antiviral Organic Agents against Fish Rhabdoviruses
Shuang-Shuang Sun, Shi-Wei Ma, Jun Li, Qin Zhang, Guang-Zhou Zhou
Fishes.2023; 8(1): 57. CrossRef - Comprehensive review on infectious pancreatic necrosis virus
Irtifa Fayaz, Raja Aadil Hussain Bhat, Ritesh Shantilal Tandel, Pragyan Dash, Suresh Chandra, Maneesh Kumar Dubey, Parvaiz Ahmad Ganie
Aquaculture.2023; 574: 739737. CrossRef - The Potential of Algae in the Nutricosmetic Sector
Irene Dini
Molecules.2023; 28(10): 4032. CrossRef - Phylogenetic distribution of bromophenols in marine algae and the generation of a comprehensive bromophenol database
Joshua Jacobtorweihen, Verena Spiegler
Phytochemistry Reviews.2023; 22(3): 505. CrossRef - Unveiling the Potential of Algal Extracts as Promising Antibacterial and Antibiofilm Agents against Multidrug-Resistant Pseudomonas aeruginosa: In Vitro and In Silico Studies including Molecular Docking
Shimaa El-Sapagh, Rania El-Shenody, Leonel Pereira, Mostafa Elshobary
Plants.2023; 12(18): 3324. CrossRef - Macroalgae Specialized Metabolites: Evidence for Their Anti-Inflammatory Health Benefits
Djenisa H. A. Rocha, Diana C. G. A. Pinto, Artur M. S. Silva
Marine Drugs.2022; 20(12): 789. CrossRef - 3-Bromo-4,5-dihydroxybenzaldehyde Isolated from Polysiphonia morrowii Suppresses TNF-α/IFN-γ-Stimulated Inflammation and Deterioration of Skin Barrier in HaCaT Keratinocytes
Arachchige Maheshika Kumari Jayasinghe, Eui-Jeong Han, Kirinde Gedara Isuru Sandanuwan Kirindage, Ilekuttige Priyan Shanura Fernando, Eun-A Kim, Junseong Kim, Kyungsook Jung, Kil-Nam Kim, Soo-Jin Heo, Ginnae Ahn
Marine Drugs.2022; 20(9): 563. CrossRef - Viral infections in cultured fish and shrimps: current status and treatment methods
Haimanti Mondal, Natarajan Chandrasekaran, Amitava Mukherjee, John Thomas
Aquaculture International.2022; 30(1): 227. CrossRef - Amino Acid-Coupled Bromophenols and a Sulfated Dimethylsulfonium Lanosol from the Red Alga Vertebrata lanosa
Joshua Jacobtorweihen, Marthe Schmitt, Verena Spiegler
Marine Drugs.2022; 20(7): 420. CrossRef - Phytocompounds as an Alternative Antimicrobial Approach in Aquaculture
Naqiuddin Nik Mohamad Nek Rahimi, Ikhsan Natrah, Jiun-Yan Loh, Francis Kumar Ervin Ranzil, Madi Gina, Swee-Hua Erin Lim, Kok-Song Lai, Chou-Min Chong
Antibiotics.2022; 11(4): 469. CrossRef - 5-Bromo-3,4-dihydroxybenzaldehyde Promotes Hair Growth through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells
Jung-Il Kang, Youn Kyung Choi, Sang-Chul Han, Hyunwoo Nam, Gilwoo Lee, Ji-Hoon Kang, Young Sang Koh, Jin Won Hyun, Eun-Sook Yoo, Hee-Kyoung Kang
Molecules.2022; 27(7): 2176. CrossRef - Anti-Allergic Effect of 3,4-Dihydroxybenzaldehyde Isolated from Polysiphonia morrowii in IgE/BSA-Stimulated Mast Cells and a Passive Cutaneous Anaphylaxis Mouse Model
Eun-A Kim, Eui-Jeong Han, Junseong Kim, Ilekuttige Priyan Shanura Fernando, Jae-Young Oh, Kil-Nam Kim, Ginnae Ahn, Soo-Jin Heo
Marine Drugs.2022; 20(2): 133. CrossRef - Novel marine bioactives: application in functional foods, nutraceuticals, and pharmaceuticals
Fereidoon Shahidi, Sarusha Santhiravel
Journal of Food Bioactives.2022; : 4. CrossRef - Antiviral Activity of Ribavirin against Tilapia tilapinevirus in Fish Cells
Tuchakorn Lertwanakarn, Pirada Trongwongsa, Sangchai Yingsakmongkol, Matepiya Khemthong, Puntanat Tattiyapong, Win Surachetpong
Pathogens.2021; 10(12): 1616. CrossRef - Antimicrobials from Seaweeds for Food Applications
Eduarda M. Cabral, Márcia Oliveira, Julie R. M. Mondala, James Curtin, Brijesh K. Tiwari, Marco Garcia-Vaquero
Marine Drugs.2021; 19(4): 211. CrossRef - Compilation of antiviral treatments and strategies to fight fish viruses
Patricia Pereiro, Antonio Figueras, Beatriz Novoa
Reviews in Aquaculture.2021; 13(3): 1223. CrossRef - Anti-senescence and anti-wrinkle activities of 3—bromo—4,5—dihydroxybenzaldehyde from Polysiphonia morrowii Harvey in human dermal fibroblasts
Su-Hyeon Cho, Eun-Yi Ko, Soo-Jin Heo, Seo-Young Kim, Juhee Ahn, Kil-Nam Kim
Asian Pacific Journal of Tropical Biomedicine.2021; 11(2): 74. CrossRef - Progress of Bromophenols in Marine Algae from 2011 to 2020: Structure, Bioactivities, and Applications
Hui Dong, Songtao Dong, Poul Erik Hansen, Dimitrios Stagos, Xiukun Lin, Ming Liu
Marine Drugs.2020; 18(8): 411. CrossRef - Seaweed Phenolics: From Extraction to Applications
João Cotas, Adriana Leandro, Pedro Monteiro, Diana Pacheco, Artur Figueirinha, Ana M. M. Gonçalves, Gabriela Jorge da Silva, Leonel Pereira
Marine Drugs.2020; 18(8): 384. CrossRef - Potential Use of Marine Seaweeds as Prebiotics: A Review
Aroa Lopez-Santamarina, Jose Manuel Miranda, Alicia del Carmen Mondragon, Alexandre Lamas, Alejandra Cardelle-Cobas, Carlos Manuel Franco, Alberto Cepeda
Molecules.2020; 25(4): 1004. CrossRef -
Addition of the red macroalgae Turkish Towel
Chondracanthus exasperates
and taurine improves the performance of alternative plant‐based feeds for juvenile sablefish
Anoplopoma fimbria
Ronald B. Johnson, Peter M. Nicklason, Lisa C. Armbruster, Frank C. Sommers, Shin‐Kwon Kim, David Marancik, Junghoon Jee, Brad A. Gadberry, John E. Colt
Aquaculture Research.2020; 51(8): 3191. CrossRef - Bioactive Properties of Marine Phenolics
Raquel Mateos, José Ricardo Pérez-Correa, Herminia Domínguez
Marine Drugs.2020; 18(10): 501. CrossRef - Biologically active macromolecules: Extraction strategies, therapeutic potential and biomedical perspective
Muhammad Bilal, Hafiz M.N. Iqbal
International Journal of Biological Macromolecules.2020; 151: 1. CrossRef - Isolation and Potential Biological Applications of Haloaryl Secondary Metabolites from Macroalgae
Ana Jesus, Marta Correia-da-Silva, Carlos Afonso, Madalena Pinto, Honorina Cidade
Marine Drugs.2019; 17(2): 73. CrossRef - Marine Compound 3-Bromo-4,5-dihydroxybenzaldehyde Protects Skin Cells against Oxidative Damage via the Nrf2/HO-1 Pathway
Yea Ryu, Pincha Fernando, Kyoung Kang, Mei Piao, Ao Zhen, Hee Kang, Young Koh, Jin Hyun
Marine Drugs.2019; 17(4): 234. CrossRef - Simultaneous use of oxalate-degrading bacteria and herbal extract to reduce the urinary oxalate in a rat model: A new strategy
Rouhi Afkari, Mohammad Mehdi Feizabadi, Alireza Ansari-Moghadam, Tahereh Safari, Mohammad Bokaeian
International braz j urol.2019; 45(6): 1249. CrossRef - 3‑Bromo‑5‑(ethoxymethyl)‑1,2‑benzenediol inhibits LPS-induced pro-inflammatory responses by preventing ROS production and downregulating NF-κB in vitro and in a zebrafish model
Eun-Yi Ko, Soo-Jin Heo, Su-Hyeon Cho, WonWoo Lee, Seo-Young Kim, Hye-Won Yang, Ginnae Ahn, Seon-Heui Cha, Seung-Hae Kwon, Myeong Seon Jeong, Kang Pa Lee, You-Jin Jeon, Kil-Nam Kim
International Immunopharmacology.2019; 67: 98. CrossRef - Ursolic acid from Prunella vulgaris L. efficiently inhibits IHNV infection in vitro and in vivo
Bo-Yang Li, Yang Hu, Jian Li, Kai Shi, Yu-Feng Shen, Bin Zhu, Gao-Xue Wang
Virus Research.2019; 273: 197741. CrossRef - Synthesis and antiviral activity of a new arctigenin derivative against IHNV in vitro and in vivo
Yang Hu, Wei-Chao Chen, Yu-Feng Shen, Bin Zhu, Gao-Xue Wang
Fish & Shellfish Immunology.2019; 92: 736. CrossRef - 3-Bromo-4,5-Dihydroxybenzaldehyde Protects Against Myocardial Ischemia and Reperfusion Injury Through the Akt-PGC1α-Sirt3 Pathway
Shu-Guang Qin, Hong-Yan Tian, Jin Wei, Zhen-Hua Han, Ming-Juan Zhang, Guang-Hua Hao, Xin Liu, Long-Fei Pan
Frontiers in Pharmacology.2018;[Epub] CrossRef - Efficacy of algal Ecklonia cava extract against viral hemorrhagic septicemia virus (VHSV)
Han-Kook Yang, Myung-Hwa Jung, Satheesha Avunje, Chamilani Nikapitiya, So Young Kang, Young Bae Ryu, Woo Song Lee, Sung-Ju Jung
Fish & Shellfish Immunology.2018; 72: 273. CrossRef - Treatment with 3-Bromo-4,5-Dihydroxybenzaldehyde Improves Cardiac Function by Inhibiting Macrophage Infiltration in Mice
Ningning Ji, Honghong Lou, Xinyan Gong, Ting Fu, Shimao Ni
Korean Circulation Journal.2018; 48(10): 933. CrossRef - The Red Algae Compound 3-Bromo-4,5-dihydroxybenzaldehyde Protects Human Keratinocytes on Oxidative Stress-Related Molecules and Pathways Activated by UVB Irradiation
Mei Piao, Kyoung Kang, Yea Ryu, Kristina Shilnikova, Jeong Park, Yu Hyun, Ao Zhen, Hee Kang, Young Koh, Mee Ahn, Jin Hyun
Marine Drugs.2017; 15(9): 268. CrossRef - Anti-Inflammatory Effect of 3-Bromo-4,5-Dihydroxybenzaldehyde, a Component ofPolysiphonia morrowii,In VivoandIn Vitro
Na-Jin Kang, Sang-Chul Han, Hyun-Jae Kang, Geum Ko, Weon-Jong Yoon, Hee-Kyoung Kang, Eun-Sook Yoo
Toxicological Research.2017; 33(4): 325. CrossRef - 3-Bromo-4,5-dihydroxybenzaldehyde Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes
Ki Kim, Yu Hyun, Susara Ruwan Hewage, Mei Piao, Kyoung Kang, Hee Kang, Young Koh, Mee Ahn, Jin Hyun
Marine Drugs.2017; 15(9): 291. CrossRef - Expanding our Understanding of the Seaweed Holobiont: RNA Viruses of the Red Alga Delisea pulchra
Tim Lachnit, Torsten Thomas, Peter Steinberg
Frontiers in Microbiology.2016;[Epub] CrossRef - Algae as production systems of bioactive compounds
Izabela Michalak, Katarzyna Chojnacka
Engineering in Life Sciences.2015; 15(2): 160. CrossRef - Seaweed extracts as antimicrobial agents in aquaculture
Ioannis N Vatsos, Celine Rebours
Journal of Applied Phycology.2015; 27(5): 2017. CrossRef - Bis(2,3-dibromo-4,5-dihydroxybenzyl) Ether, a Marine Algae Derived Bromophenol, Inhibits the Growth of Botrytis cinerea and Interacts with DNA Molecules
Ming Liu, Genzhu Wang, Lin Xiao, Xuanli Xu, Xiaohui Liu, Pingxiang Xu, Xiukun Lin
Marine Drugs.2014; 12(7): 3838. CrossRef - In vitro Anti-bacterial and Anti-scuticociliate Activities of Extract and Bromophenols of the Marine Red Alga Polysiphonia morrowii with Structure-activity Relationships
So Young Kang, Sang-Yun Lee, Jun-Ho Choi, Sung-Ju Jung
Korean Journal of Fisheries and Aquatic Sciences.2014; 47(1): 45. CrossRef - Antimicrobial Activity of Honey Bee Venom against Select Infectious Fish Pathogens
Sang Mi Han, Kwang Gill Lee, Kwan Kyu Park, Sok Cheon Pak
North American Journal of Aquaculture.2013; 75(3): 445. CrossRef - Photo-protective effect of Polysiphonia morrowii Harvey against ultraviolet B radiation-induced keratinocyte damage
Mei Jing Piao, Hee Kyoung Kang, Eun Sook Yoo, Young Sang Koh, Dong Sam Kim, Nam Ho Lee, Jin Won Hyun
Journal of the Korean Society for Applied Biological Chemistry.2012; 55(2): 149. CrossRef - Antiviral activities of flavonoids isolated from the bark of Rhus verniciflua stokes against fish pathogenic viruses In Vitro
So Young Kang, Ji-Young Kang, Myung-Joo Oh
The Journal of Microbiology.2012; 50(2): 293. CrossRef - Photo-protection by 3-bromo-4, 5-dihydroxybenzaldehyde against ultraviolet B-induced oxidative stress in human keratinocytes
Yu Jae Hyun, Mei Jing Piao, Rui Zhang, Yung Hyun Choi, Sungwook Chae, Jin Won Hyun
Ecotoxicology and Environmental Safety.2012; 83: 71. CrossRef - Bromophenols in Marine Algae and Their Bioactivities
Ming Liu, Poul Erik Hansen, Xiukun Lin
Marine Drugs.2011; 9(7): 1273. CrossRef
- DNA Sequence of the phnN Gene for Benzaldehyde Dehydrogenase form Pseudomonas sp. DJ77 and Its Substrate Preference
-
Seong-Jae Kim , Soonyoung Hwang , Young-Chang Kim
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J. Microbiol. 1999;37(4):224-228.
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Abstract
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Benzaldehyle dehydrogenase (BZDH), an enzyme involved in the degradation of toluene and xylenes, is encoded by the phnN gene of Pseudomonas sp. strain DJ77. We determined the nucleotide sequence of a DNA fragment of 1,803 base pairs which included the phnN gene. The fragment contained an open reading frame of 1,506 base pairs to accommodate th 55 kDa sized enzyme encoding BZDH. The enzyme efficiently oxidized benzaldehyde, salicylaldehyde, m-tolualdehyde and ps-tolualdehyde.