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Research Support, Non-U.S. Gov't
- Antibacterial metabolites from the Actinomycete Streptomyces sp. P294
- Huining Su , Hongwei Shao , Keqin Zhang , Guohong Li
- J. Microbiol. 2016;54(2):131-135. Published online February 2, 2016
- DOI: https://doi.org/10.1007/s12275-016-5311-9
- 47 View
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- 5 Crossref
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Abstract
- The Actinomycete strain P294 was isolated from soil and identified as Streptomyces sp. based upon the results of 16S rRNA sequence analysis. Three compounds obtained from the solid fermentation products of this strain have been determined by 1D, 2D NMR and HRMS experiments. These compounds include two new compounds angumycinones C (1) and D (2), and the known compound X-14881 E (3). All compounds were assayed for antibacterial and nematicidal activity. The results showed the three compounds had different degrees of inhibitory activity against several target bacteria but no significant toxicity against the nematode Caenorhabditis elegans.
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- Identification, fermentation optimization, and biocontrol efficacy of actinomycete YG-5 for the prevention of Alternaria leaf spot disease in star anise
Jieming Pan, Xiaoshan Geng, Yujing Cai, Ye Yu, Yanrong Hou, Yao Liu, Caina Ya, Qin Liu
Scientific Reports.2024;[Epub] CrossRef - Diverse ansamycin derivatives from the marine-derived Streptomyces sp. ZYX-F-97 and their antibacterial activities
Ke-Xin Yi, Qing-Yi Xie, Qing-Yun Ma, Li Yang, Hao-Fu Dai, You-Xing Zhao, Yu-E Hao
Fitoterapia.2024; 173: 105814. CrossRef - Heterologous Expression of Type II PKS Gene Cluster Leads to Diversified Angucyclines in Streptomyces albus J1074
Xiaoting Zhang, Falei Zhang, Chen Li, Jiayi Li, Xiao Xu, Tianjiao Zhu, Qian Che, Deihai Li, Guojian Zhang
Marine Drugs.2024; 22(11): 480. CrossRef - Streptomyces sp. AN090126 as a Biocontrol Agent against Bacterial and Fungal Plant Diseases
Khanh Duy Le, Nan Hee Yu, Ae Ran Park, Dong-Jin Park, Chang-Jin Kim, Jin-Cheol Kim
Microorganisms.2022; 10(4): 791. CrossRef - Soluble macromolecules from two Streptomyces strains with potent nematicidal activity against Meloidogyne incognita
Qianru Hu, Minmin Yang, Tingting Bo, Yuxin Li, Caimi Wu, Minghe Mo, Yajun Liu
Rhizosphere.2022; 22: 100529. CrossRef
- Identification, fermentation optimization, and biocontrol efficacy of actinomycete YG-5 for the prevention of Alternaria leaf spot disease in star anise
Journal Article
- Nematicidal Activity of Paecilomyces spp. and Isolation of a Novel Active Compound
- Ya-Jun Liu , Chong-Yan Zhai , Yi Liu , Ke-Qin Zhang
- J. Microbiol. 2009;47(3):248-252. Published online June 26, 2009
- DOI: https://doi.org/10.1007/s12275-009-0012-2
- 36 View
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- 14 Scopus
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Abstract
- Many species of Paecilomyces are entomogenous fungi and several are efficacious toward nematodes. To study the potential of Paecilomyces species in controlling nematodes, fungal extracts of 40 Paecilomyces spp. were evaluated for their nematicidal activity against Bursaphelenchus xylophilus and Panagrellus redivivus. The extracts of six Paecilomyces spp. exhibited the nematicidal activity against P. redivivus, and 11 species exhibited the nematicidal activity against B. xylophilus. The methanol extract of strain 1.01761 incubating on Czapek solid medium killed more than 95% P. redivivus in 24 h at 5 mg/ml, and the filtrate of strain 1.01788 cultured in Sabouraud''s broth medium resulted in 90% mortality of B. xylophilus in 24 h at 5 mg/ml. A novel nematicidal compound, 4-(4’-carboxy-2’-ethyl-hydroxypentyl)-5,6-dihydro-6-methylcyclobuta[b]pyridine-3,6-dicarboxylic acid, was isolated from Paecilomyces sp. YMF1.01761. The LD50 value of the compound within 24 h against P. redivivus was 50.86 mg/L, against Meloidogyne incognita was 47.1 mg/L, and against B. xylophilus was 167.7 mg/L.
Research Support, Non-U.S. Gov't
- Nematicidal Activity and Chemical Component of Poria cocos
- Guo Hong Li , Yue Mao Shen , Ke Qin Zhang
- J. Microbiol. 2005;43(1):17-20.
- DOI: https://doi.org/2144 [pii]
- 40 View
- 0 Download
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Abstract
- Poria cocos, a famous traditional Chinese medicine, was found to have nematicidal activity in experiments searching for nematicidal fungi. The experiment showed it could kill 94.9% of the saprophytic nematode, Panagrellus redivivue, 92.6% of the root-knot nematode, Meloidogyne arenaria, and 93.5% of the pine nematode, Bursaphelenchus xylophilus, on PDA plate within 12 hours. According to the nematicidal activity, three new compounds, 2, 4, 6-triacetylenic octane diacid, 2, 4, 5, 6-tetrahydroxyhexanoic acid and 3, 4-dihydroxy-2-keto-n-butyl 2,4,5,6-tetrahydroxyhexanate, were isolated from submerged cultures of Poria cocos. Of these, 2, 4, 6-triacetylenic octane diacid could kill 83.9% Meloidogyne arenaria and 73.4% Panagrellus redivivus at 500 ppm within 12 hours. Here, it is reported for the first time that Poria cocos has nematicidal activity.
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