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Analysis of Substitution Events in HIV-1 vif Gene of the Korean Clade
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HOME > J. Microbiol > Volume 45(1); 2007 > Article
Research Support, Non-U.S. Gov't
Analysis of Substitution Events in HIV-1 vif Gene of the Korean Clade
Chan Seung Park 1, Mi Sook Kim 1, Hyun Ah Yi 1, Dong Hun Lee 1, Keon Myung Lee 2, Chan Hee Lee 1
Journal of Microbiology 2007;45(1):75-78
DOI: https://doi.org/2487 [pii]
1School of Life Sciences Chungbuk National University, Cheongju, Republic of Korea, 2School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Republic of Korea1School of Life Sciences Chungbuk National University, Cheongju, Republic of Korea, 2School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Republic of Korea
Corresponding author:  Chan Hee Lee , Tel: 82-43-261-2304, 
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Abstract

Nucleotide and amino acid substitution pattern in vif gene of the Korean clade of HIV-1 isolated from Koreans were analyzed using consensus sequences. At nucleotide level, transition/transversion substitution ratio was 1.88, and nonsynonymous/synonymous substitution ratio was 2.67, suggesting a divergent
evolution in the Korean clade. At amino acid level, there were 17 substitutions and G→E substitution at position 37 may be responsible for change in predicted secondary structure.

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    Analysis of Substitution Events in HIV-1 vif Gene of the Korean Clade
    J. Microbiol. 2007;45(1):75-78.
    DOI: https://doi.org/2487 [pii]
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