Journal of Microbiology

Review

MINIREVIEW]Phytochemicals for the treatment of COVID-19: Erica Españo , Jiyeon Kim , Kiho Lee , Jeong-Ki Kim; J. Microbiol. 2021;59(11):959-977. Published online November 1, 2021; DOI: https://doi.org/10.1007/s12275-021-1467-z

47 View
0 Download
17 Web of Science
18 Crossref

The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle.

Citations

Citations to this article as recorded by

Role of dietary supplements in the continuous battle against COVID‐19
Rahela Zaman, Vignesh Ravichandran, Chung Keat Tan
Phytotherapy Research.2024; 38(2): 1071. CrossRef
The Potential of Anti-coronavirus Plant Secondary Metabolites in COVID-19 Drug Discovery as an Alternative to Repurposed Drugs: A Review
Zahra Alipour, Somayeh Zarezadeh, Ali Akbar Ghotbi-Ravandi
Planta Medica.2024; 90(03): 172. CrossRef
In Silico Screening of Some Active Phytochemicals to Identify Promising Inhibitors Against SARS-CoV-2 Targets
V. Alagarsamy, V. Raja Solomon, S. Murugesan, P. Shyam Sundar, MD. Muzaffar-Ur-Rehman, A. Chandu, A. Dharshini Aishwarya, B. Narendhar, M.T. Sulthana, V. Ravikumar
Current Drug Discovery Technologies.2024;[Epub] CrossRef
Screening Commercial Tea for Rapid Inactivation of Infectious SARS-CoV-2 in Saliva
Julianna N. Morris, Malak A. Esseili
Food and Environmental Virology.2024; 16(2): 159. CrossRef
Phytochemical-loaded Nanoparticles in COVID-19 Management
Suneetha Vuppu, Toshika Mishra, Shatakshi Mishra, Stany B, Anushka Das
Natural Resources for Human Health.2023; 4(1): 51. CrossRef
Nutritional deficiencies that may predispose to long COVID
John V. Schloss
Inflammopharmacology.2023; 31(2): 573. CrossRef
Curcumin-Based Nanomedicines in the Treatment of Inflammatory and Immunomodulated Diseases: An Evidence-Based Comprehensive Review
Lucas Fornari Laurindo, Gabriel Magno de Carvalho, Bárbara de Oliveira Zanuso, Maria Eduardo Figueira, Rosa Direito, Ricardo de Alvares Goulart, Daiene Santos Buglio, Sandra Maria Barbalho
Pharmaceutics.2023; 15(1): 229. CrossRef
Changes in phytochemical compositions and antioxidant activity of Schisandra sphenathera fruit during ripening
Bohan Ma, Xinghua Zhao, Bin Dai, Mengge Zhao, Xingbin Yang, Langjun Cui, Hongjun Shao
Industrial Crops and Products.2023; 199: 116773. CrossRef
Role of nutrition in minimizing mental and health-related issues during COVID-19: a systematic literature review
Luxita Sharma, Dhananjay Sharma
Nutrition & Food Science.2023; 53(4): 659. CrossRef
Current Update of Phytotherapeutic Agents in the Treatment of COVID-19: In-Silico Based Virtual Screening Approach for the Development of Antiviral Drug
Veena Ramesh, Seema A. Kulkarni, Palaniyandi Velusamy, Velmurugan Devadasan, Panneer Devaraju, Kandathil Narayanan Rajnish, Thirumurthy Madhavan, Periasamy Anbu, Palaniappan Ramasamy, Rajamanikandan Sundarraj
Frontiers in Bioscience-Landmark.2022;[Epub] CrossRef
Promising natural products against SARS‐CoV‐2: Structure, function, and clinical trials
Yan Zhao, Shanshan Deng, Yujiao Bai, Jinlin Guo, Guoyin Kai, Xinhe Huang, Xu Jia
Phytotherapy Research.2022; 36(10): 3833. CrossRef
Effective food hygiene principles and dietary intakes to reinforce the immune system for prevention of COVID-19: a systematic review
Jalaledin Mirzay-Razaz, Majid Hassanghomi, Marjan Ajami, Glareh Koochakpoor, Firoozeh Hosseini-Esfahani, Parvin Mirmiran
BMC Nutrition.2022;[Epub] CrossRef
Beneficial effect of polyphenols in COVID‐19 and the ectopic F1FO‐ATP synthase: Is there a link?
Isabella Panfoli, Alfonso Esposito
Journal of Cellular Biochemistry.2022; 123(8): 1281. CrossRef
In vitro inhibition of SARS-CoV-2 Infection by dry algae powders
Daniel Garcia-Ruiz, Erendira Villalobos-Sánchez, David Alam-Escamilla, Darwin Elizondo-Quiroga
Scientific Reports.2022;[Epub] CrossRef
Schizophyllum commune Reduces Expression of the SARS-CoV-2 Receptors ACE2 and TMPRSS2
Te-Kai Sun, Wen-Chin Huang, Yu-Wen Sun, Jeng-Shyan Deng, Liang-Hsuan Chien, Ya-Ni Chou, Wen-Ping Jiang, Jaung-Geng Lin, Guan-Jhong Huang
International Journal of Molecular Sciences.2022; 23(23): 14766. CrossRef
An exhaustive comprehension of the role of herbal medicines in Pre- and Post-COVID manifestations
Shiv Kumar Prajapati, Akanksha Malaiya, Gaurav Mishra, Dolly Jain, Payal Kesharwani, Nishi Mody, Amirhossein Ahmadi, Rishi Paliwal, Ankit Jain
Journal of Ethnopharmacology.2022; 296: 115420. CrossRef
Computational screening for investigating the synergistic regulatory potential of drugs and phytochemicals in combination with 2-deoxy-D-glucose against SARS-CoV-2
Anshika Gupta, Shweta Singh Chauhan, Anamika Singh Gaur, Ramakrishnan Parthasarathi
Structural Chemistry.2022; 33(6): 2179. CrossRef
BOTANICALS AS PROSPECTIVE AGENTS AGAINST SARS-COV-2 VIRUS
V. DUSHENKOV, A. DUSHENKOV
AVICENNA BULLETIN.2022; 24(1): 113. CrossRef

Journal Articles

Optimization of bacterial sporulation using economic nutrient for self-healing concrete: Youngung Ryu , Ki-Eun Lee , In-Tae Cha , Woojun Park; J. Microbiol. 2020;58(4):288-296. Published online February 27, 2020; DOI: https://doi.org/10.1007/s12275-020-9580-y

45 View
0 Download
17 Web of Science
19 Crossref

Abstract

The use of heat- and alkali-resistant bacteria is essential for the biological repair of damaged concrete. Lysinibacillus boronitolerans YS11 was isolated from the rhizosphere of Miscanthus sacchariflorus. The increased pH in the urea-minus condition during the growth of the YS11 strain promoted calcium carbonate (CaCO3) formation. To identify the optimum medium that promoted the growth of the YS11 strain, a Plackett- Burman design was conducted for the screening process. Consequently, malt powder, rice bran, (NH4)2SO4, and corn syrup were chosen to enhance YS11 growth. The optimization of these four useful factors was carried out using a central composite design. To obtain higher survivability in mortar, the sporulation process is essential, and additional factors such as Mn2+, Fe2+, and Ca2+ were found to contribute to sporulation. A mixture of L. boronitolerans YS11 spore powder, cement, paste, sand, yeast extract, calcium lactate, and water showed a healing effect on a 0.3 mm mortar crack in 7 days. Furthermore, calcium carbonate precipitation was observed over the crack surface. Thus, we confirmed that mortar treated with YS11 spore powder was effective in healing micro-cracks in concrete.

Citations

Citations to this article as recorded by

Self-Healing Concrete Utilizing Ureolysis Mechanism of Microbially Induced Calcite Precipitation (MICP): a Review
Yea Shiuan Kho, Kwong Soon Wong, Nurul Noraziemah Mohd Pauzi, Meheron Selowara Joo, Tony Hadibarata
Iranian Journal of Science and Technology, Transactions of Civil Engineering.2024;[Epub] CrossRef
Enhanced mechanical and self-healing properties of rice husk ash-incinerated sugarcane press mud biogeopolymer pastes
Aunchanida Techo, Darunee Kaewpikul, Vanchai Sata, Nantawat Tanapongpisit, Suchunya Wongprasod, Wittawat Saenrang, Poemwai Chainakun, Prinya Chindaprasirt, Jindarat Ekprasert
Scientific Reports.2024;[Epub] CrossRef
Collective Mapping of Gas Leakages to Determine Safe Routes Using Multi-Robot System
Ronnier Frates Rohrich, Luís Felipe Messias, Jose Lima, André Schneider de Oliveira
IEEE Access.2024; 12: 179764. CrossRef
A comprehensive review on the application of microbially induced calcite precipitation (MICP) technique in soil erosion mitigation as a sustainable and environmentally friendly approach
Meghdad Payan, Moein Khoshdel Sangdeh, Mahdi Salimi, Payam Zanganeh Ranjbar, Mahyar Arabani, Iman Hosseinpour
Results in Engineering.2024; 24: 103235. CrossRef
The use of coffee waste in bio-foamed concrete brick (B-FCB) to reduce the penetration of carbon dioxide (CO2) into concrete
Abdullah Faisal Alshalif, Y M Azril, J M Irwan, A Mutafi, Honin Ali Yahya Alshaeer, S J S Hakim
IOP Conference Series: Earth and Environmental Science.2024; 1347(1): 012080. CrossRef
Treatment of fractured concrete via microbially induced carbonate precipitation: From micro-scale characteristics to macro-scale behaviour
Ronald Turner, Gloria M. Castro, James Minto, Grainne El Mountassir, Rebecca J. Lunn
Construction and Building Materials.2023; 384: 131467. CrossRef
Microbial‑induced carbonate precipitation (MICP) technology: a review on the fundamentals and engineering applications
Kuan Zhang, Chao-Sheng Tang, Ning-Jun Jiang, Xiao-Hua Pan, Bo Liu, Yi-Jie Wang, Bin Shi
Environmental Earth Sciences.2023;[Epub] CrossRef
A design of experiments screen reveals that Clostridium novyi-NT spore germinant sensing is stereoflexible for valine and its analogs
Ajitha Sundaresan, Mai Le Ngoc, Marvell Ung Wew, Varsha Ramkumar, Prahlad Raninga, Rongji Sum, Ian Cheong
Communications Biology.2023;[Epub] CrossRef
Effects of Various Pseudomonas Bacteria Concentrations on the Strength and Durability Characteristics of Concrete
Ashish Shukla, Nakul Gupta, Saurav Dixit, Nikolai Ivanovich Vatin, Manish Gupta, Kuldeep Kumar Saxena, Chander Prakash
Buildings.2022; 12(7): 993. CrossRef
Optimisation of self-healing of bio-foamed concrete bricks pores using Bacillus tequilensis under different temperature and CO2 curing conditions
Abdullah F. Alshalif, M. Irwan Juki, Husnul Azan Tajarudin, N. Othman, Adel Ali Al-Gheethi, S. Shamsudin, Wahid Altowayti, Saddam Abo Sabah
Scientific Reports.2022;[Epub] CrossRef
Potential of cave isolated bacteria in self-healing of cement-based materials
Nicole Schwantes-Cezario, Lucca Vieira Cremasco, Leonardo Pinto Medeiros, Gustavo Manoel Teixeira, Ulisses Brigatto Albino, Luis Eduardo Azevedo Marques Lescano, Leopoldo Sussumu Matsumoto, Admilton Gonçalves de Oliveira, Paulo Rogério Catarini da Silva,
Journal of Building Engineering.2022; 45: 103551. CrossRef
Performance Evaluation of Bio Concrete by Cluster and Regression Analysis for Environment Protection
Ashish Shukla, Nakul Gupta, Kunwar Raghvendra Singh, Pawan Kumar Verma, Mohit Bajaj, Arfat Ahmad Khan, Frie Ayalew, Anastasios D. Doulamis
Computational Intelligence and Neuroscience.2022; 2022: 1. CrossRef
Relationship between Bacterial Contribution and Self-Healing Effect of Cement-Based Materials
Olja Šovljanski, Ana Tomić, Siniša Markov
Microorganisms.2022; 10(7): 1399. CrossRef
Advancements in bacteria based self-healing concrete and the promise of modelling
Manpreet Bagga, Charlotte Hamley-Bennett, Aleena Alex, Brubeck L Freeman, Ismael Justo-Reinoso, Iulia C Mihai, Susanne Gebhard, Kevin Paine, Anthony D Jefferson, Enrico Masoero, Irina D Ofiţeru
Construction and Building Materials.2022; 358: 129412. CrossRef
Review of autonomous self-healing cementitious material
S A Susanto, D Hardjito, A Antoni
IOP Conference Series: Earth and Environmental Science.2021; 907(1): 012006. CrossRef
Agricultural by-products and oyster shell as alternative nutrient sources for microbial sealing of early age cracks in mortar
Minyoung Hong, Indong Jang, Yongjun Son, Chongku Yi, Woojun Park
AMB Express.2021;[Epub] CrossRef
Raman spectroscopy reveals alteration of spore compositions under different nutritional conditions in Lysinibacillus boronitolerans YS11
Youngung Ryu, Minyoung Hong, Soo Bin Kim, Tae Kwon Lee, Woojun Park
Journal of Microbiology.2021; 59(5): 491. CrossRef
Influences of different calcium sources on the early age cracks of self-healing cementitious mortar
Tianwen Zheng, Chunxiang Qian, Yilin Su
Biochemical Engineering Journal.2021; 166: 107849. CrossRef
Effect and Mechanism of Encapsulation-Based Spores on Self-Healing Concrete at Different Curing Ages
Tianwen Zheng, Yilin Su, Xuan Zhang, Hengyi Zhou, Chunxiang Qian
ACS Applied Materials & Interfaces.2020; 12(47): 52415. CrossRef

The hyperthermophilic α-amylase from Thermococcus sp. HJ21 does not require exogenous calcium for thermostability because of high-binding affinity to calcium: Huaixu Cheng , Zhidan Luo , Mingsheng Lu , Song Gao , Shujun Wang; J. Microbiol. 2017;55(5):379-387. Published online March 1, 2017; DOI: https://doi.org/10.1007/s12275-017-6416-5

44 View
0 Download
9 Crossref

Abstract

The hyperthermophilic α-amylase from Thermococcus sp. HJ21 does not require exogenous calcium ions for thermo-stability, and is a promising alternative to commercially avail-able α-amylases to increase the efficiency of industrial pro-cesses like the liquefaction of starch. We analyzed the amino acid sequence of this α-amylase by sequence alignments and structural modeling, and found that this α-amylase closely resembles the α-amylase from Pyrococcus woesei. The gene of this α-amylase was cloned in Escherichia coli and the re-combinant α-amylase was overexpressed and purified with a combined renaturation-purification procedure. We con-firmed thermostability and exogenous calcium ion indepen-dency of the recombinant α-amylase and further investigated the mechanism of the independency using biochemical ap-proaches. The results suggested that the α-amylase has a high calcium ion binding affinity that traps a calcium ion that would not dissociate at high temperatures, providing a direct expla-nation as to why the addition of calcium ions is not required for thermostability. Understanding of the mechanism offers a strong base on which to further engineer properties of this α-amylase for better potential applications in industrial pro-cesses.

Citations

Citations to this article as recorded by

Enhanced Thermostability of Geobacillus stearothermophilus α-Amylase by Rational Design of Disulfide Bond and Application in Corn Starch Liquefaction and Bread Quality Improvement
Mengyu Zhu, Wenxin Zhai, Runfei Song, Lin Lin, Wei Wei, Dongzhi Wei
Journal of Agricultural and Food Chemistry.2023; 71(48): 18928. CrossRef
Structural and functional adaptation in extremophilic microbial α-amylases
Aziz Ahmad, Rahamtullah, Rajesh Mishra
Biophysical Reviews.2022; 14(2): 499. CrossRef
Biochemical characterization of an α-fucosidase PsaFuc from the GH29 family
Xiaohua Liu, Xin Geng, Weizhi Liu, Qianqian Lyu
Process Biochemistry.2022; 122: 258. CrossRef
Amylases from thermophilic bacteria: structure and function relationship
Bhavtosh A. Kikani, Satya P. Singh
Critical Reviews in Biotechnology.2022; 42(3): 325. CrossRef
Biochemical and synergistic properties of a novel alpha‐amylase from Chinese nong‐flavor Daqu
Lanchai Chen, Zhuolin Yi, Yang Fang, Yanling Jin, Kaize He, Yao Xiao, Dong Zhao, Huibo Luo, Hui He, Qun Sun, Hai Zhao
Microbial Cell Factories.2021;[Epub] CrossRef
Recombinant expression of insoluble enzymes in Escherichia coli: a systematic review of experimental design and its manufacturing implications
Suraj Mital, Graham Christie, Duygu Dikicioglu
Microbial Cell Factories.2021;[Epub] CrossRef
A new GH13 subfamily represented by the α-amylase from the halophilic archaeon Haloarcula hispanica
Štefan Janeček, Barbora Zámocká
Extremophiles.2020; 24(2): 207. CrossRef
Contribution of domain B to the catalytic properties of a Flavobacteriaceae α-amylase
Huijia Yin, Lina Zhang, Zhou Yang, Shannan Li, Xinyu Nie, Yan Wang, Chunyu Yang
Process Biochemistry.2018; 70: 104. CrossRef
Functional and cooperative stabilization of a two-metal (Ca, Zn) center in α-amylase derived from Flavobacteriaceae species
Huijia Yin, Zhou Yang, Xinyu Nie, Shannan Li, Xuyang Sun, Chao Gao, Zenghang Wang, Guangming Zhou, Ping Xu, Chunyu Yang
Scientific Reports.2017;[Epub] CrossRef

Research Support, U.S. Gov't, Non-P.H.S.

Multiple cellular roles of Neurospora crassa plc-1, splA2, and cpe-1 in regulation of cytosolic free calcium, carotenoid accumulation, stress responses, and acquisition of thermotolerance§: Ananya Barman , Ranjan Tamuli; J. Microbiol. 2015;53(4):226-235. Published online January 31, 2015; DOI: https://doi.org/10.1007/s12275-015-4465-1

44 View
0 Download
21 Crossref

Abstract

Phospholipase C1 (PLC1), secretory phospholipase A2 (sPLA2) and Ca2+/H+ exchanger proteins regulate calcium signaling and homeostasis in eukaryotes. In this study, we investigate functions for phospholipase C1 (plc-1), sPLA2 (splA2) and a Ca2+/H+ exchanger (cpe-1) in the filamentous fungus Neurospora crassa. The Δplc-1, ΔsplA2, and Δcpe-1 mutants exhibited a growth defect on medium supplemented with the divalent ionophore A23187, suggesting that these genes might play a role in regulation of cytosolic free Ca2+ concentration ([Ca2+]c) in N. crassa. The strains lacking plc-1, splA2, and cpe-1 possessed higher carotenoid content than wild type at 8°C, 22°C, and 30°C, and showed increased ultraviolet (UV)- survival under conditions that induced carotenoid accumulation. Moreover, Δplc-1, ΔsplA2, and Δcpe-1 mutants showed reduced survival rate under hydrogen peroxide-induced oxidative stress and induced thermotolerance after exposure to heat shock temperatures. Thus, this study revealed multiple cellular roles for plc-1, splA2, and cpe-1 genes in regulation of [Ca2+]c, carotenoid accumulation, survival under stress conditions, and acquisition of thermotolerance induced by heat shock.

Citations

Citations to this article as recorded by

PacC mediates spatial regulation of the phospholipid metabolism in the apple fruit-Penicillium expansum interaction
Yatong Zhu, Yuanyuan Zong, Di Gong, Xuexue Wang, William Oyom, Yang Bi, Dov Prusky
Postharvest Biology and Technology.2024; 208: 112666. CrossRef
Methods for the detection of intracellular calcium in filamentous fungi
Megha Rasaily, Serena Ngiimei D, Rahul Kumar Thaosen, Surabhi Gupta, Sangeeta Deka, Ranjan Tamuli
MethodsX.2024; 12: 102570. CrossRef
Thiourea Application Increases Seed and Oil Yields in Camelina Under Heat Stress by Modulating the Plant Water Relations and Antioxidant Defense System
Muhammad Ahmad, Ejaz Ahmad Waraich, Usman Zulfiqar, Aman Ullah, Muhammad Farooq
Journal of Soil Science and Plant Nutrition.2023; 23(1): 290. CrossRef
Trichosporon asahii PLA2 Gene Enhances Drug Resistance to Azoles by Improving Drug Efflux and Biofilm Formation
Xiaoping Ma, Hong Liu, Zhen Liu, Ya Wang, Zhijun Zhong, Guangneng Peng, Yu Gu
International Journal of Molecular Sciences.2023; 24(10): 8855. CrossRef
Interaction of calcium responsive proteins and transcriptional factors with the PHO regulon in yeasts and fungi
Juan F. Martín
Frontiers in Cell and Developmental Biology.2023;[Epub] CrossRef
The cell functions of phospholipase C-1, Ca2+/H+ exchanger-1, and secretory phospholipase A2 in tolerance to stress conditions and cellulose degradation in Neurospora crassa
Darshana Baruah, Ranjan Tamuli
Archives of Microbiology.2023;[Epub] CrossRef
Multiple calcium signaling genes play a role in the circadian period of Neurospora crassa
Darshana Baruah, Christy Noche K Marak, Avishek Roy, Dibakar Gohain, Ajeet Kumar, Pallavi Das, Katherine A Borkovich, Ranjan Tamuli
FEMS Microbiology Letters.2023;[Epub] CrossRef
Phospholipase C: Diverse functions in plant biotic stress resistance and fungal pathogenicity
Yuanpeng Fang, Junmei Jiang, Haixia Ding, Xiangyang Li, Xin Xie
Molecular Plant Pathology.2023; 24(9): 1192. CrossRef
A secretory phospholipase A2 of a fungal pathogen contributes to lipid droplet homeostasis, assimilation of insect‐derived lipids, and repression of host immune responses
Juan Deng, Zhuoyue Lu, Huifang Wang, Ning Li, Guimei Song, Qiankuan Zhu, Jingxin Sun, Yongjun Zhang
Insect Science.2022; 29(6): 1685. CrossRef
Phospholipase C (AoPLC2) regulates mycelial development, trap morphogenesis, and pathogenicity of the nematode-trapping fungus Arthrobotrys oligospora
Meihua Xie, Ni Ma, Na Bai, Meichen Zhu, Ke-Qin Zhang, Jinkui Yang
Journal of Applied Microbiology.2022; 132(3): 2144. CrossRef
Disrupting a phospholipase A 2 gene increasing lipid accumulation in the oleaginous yeast Yarrowia lipolytica
J.X. Li, J. Xu, J.C. Ruan, H.M. Meng, H. Su, X.F. Han, M. Lu, F.L. Li, S.A. Wang
Journal of Applied Microbiology.2021; 130(1): 100. CrossRef
Flexible online in-droplet cell/synthetic particle concentration utilizing alternating current electrothermal-flow field-effect transistor
Haizhen Sun, Yukun Ren, Ye Tao, Tianyi Jiang, Hongyuan Jiang
Lab on a Chip.2021; 21(10): 1987. CrossRef
Calcium signaling is involved in diverse cellular processes in fungi
Avishek Roy, Ajeet Kumar, Darshana Baruah, Ranjan Tamuli
Mycology.2021; 12(1): 10. CrossRef
Dominant mutants of the calcineurin catalytic subunit (CNA-1) showed developmental defects, increased sensitivity to stress conditions, and CNA-1 interacts with CaM and CRZ-1 in Neurospora crassa
Ajeet Kumar, Avishek Roy, Mandar V. Deshmukh, Ranjan Tamuli
Archives of Microbiology.2020; 202(4): 921. CrossRef
Calcineurin responsive zinc‐finger‐1 binds to a unique promoter sequence to upregulate neuronal calcium sensor‐1, whose interaction with MID‐1 increases tolerance to calcium stress in Neurospora crassa
Dibakar Gohain, Ranjan Tamuli
Molecular Microbiology.2019; 111(6): 1510. CrossRef
The NcZrg-17 gene of Neurospora crassa encodes a cation diffusion facilitator transporter required for vegetative development, tolerance to endoplasmic reticulum stress and cellulose degradation under low zinc conditions
Anand Tiwari, Serena Daniel Ngiilmei, Ranjan Tamuli
Current Genetics.2018; 64(4): 811. CrossRef
Phospholipases play multiple cellular roles including growth, stress tolerance, sexual development, and virulence in fungi
Ananya Barman, Dibakar Gohain, Utpal Bora, Ranjan Tamuli
Microbiological Research.2018; 209: 55. CrossRef
The pleiotropic vegetative and sexual development phenotypes of Neurospora crassa arise from double mutants of the calcium signaling genes plc-1, splA2, and cpe-1
Ananya Barman, Ranjan Tamuli
Current Genetics.2017; 63(5): 861. CrossRef
Effects of heat stress on changes in physiology and anatomy in two cultivars of Rhododendron
H.F. Shen, B. Zhao, J.J. Xu, W. Liang, W.M. Huang, H.H. Li
South African Journal of Botany.2017; 112: 338. CrossRef
Phenotypic abnormalities of fr , sp , and och-1 single mutants are suppressed by loss of putative GPI-phospholipase A2 in Neurospora crassa
Masayuki Kamei, Yuko Tsukagoshi, Shinpei Banno, Akihiko Ichiishi, Fumiyasu Fukumori, Makoto Fujimura
Mycoscience.2017; 58(3): 137. CrossRef
Calcineurin Subunits A and B Interact to Regulate Growth and Asexual and Sexual Development in Neurospora crassa
Ranjan Tamuli, Rekha Deka, Katherine A. Borkovich, Stefanie Pöggeler
PLOS ONE.2016; 11(3): e0151867. CrossRef

Effect of Zinc and Calcium on the Intracelularly uptake of Cadimium and growth of Escherichia coli: Hong, Hyo Bong , Brown, Lewis R. , Kim, Jong Kyu; J. Microbiol. 1995;33(4):302-306.

41 View
0 Download

Abstract: E. coli was tested for their ability to uptake cadmium intracellularly, and the effect of zinc and calcium on cadmium toxicity to E. coli was observed. In addition, the effect of zinc and calcium on the uptake of cadimium was also studied. This study showed that living E. coli cells took up more cadmium than the dead cells. E. coli in the log phase uptake cadimiumm more actively than E. coli in the stationary phase. These results suggested that there may be metabolic reactions or compounds which encourage the uptake of cadimium. This study also showed that cadimium was sequestered by cell components of which molecular weight is about 30,000. Adding of zinc and calcium chloride reduced cadmium toxicity in E. coli and encouraged intracellular uptake by E coli. However adding of heavy metal solutions helped the microorganisms to adsorb more cadmium. Extremely high or low concentrations of zinc, however, did not affect cell viability.

Calcium in infectious hematopoietic necrosis virus (IHNY) infected fish cell lines: Kim, Nam Shik , Heo, Gnag Joon , Lee, Chang Hee; J. Microbiol. 1996;34(3):263-269.

38 View
0 Download

Abstract: Infection of fish cells with IHNV resulted in gradual increase in cytosolic free Ca^2+ concentration ([Ca^2+]) in CHSE, gradual decrease in [Ca^2+] in FHM, and no significant change in RTG cells. The degree of [Ca^2+] increase or decrease was dependent on the amount of infectious virus, and these [Ca^2+] variations were maximal at 16 hours after virus infection (p.i.) in both cell lines. When the fish cells were infected with inactivated IHNV, evident variation in [Ca^2+] was not observed. Thus, infectivity of IHNV appears to correlate with changes in [Ca^2+] in virus-infected cells. These IHNV-induced [Ca^2+] changes were partially blocked by cycloheximide, but not affected by cordycepin. It seems to be that virus-induced Ca^2+ variations were more related with protein synthesis than RNA synthesis. Various Ca^2+ related drugs were used in search for the mechanisms of the [Ca^2+], changes following IHNV infection of CHSE cells. Decreasing extracellular Ca^2+ concentration or blocking Ca^2+ influx from extracellular media inhibited the IHNV-induced increase in [Ca^2+], in CHSE cells. Similar results were obtained with intracellular Ca^2+ sources are important in IHNV-induced [Ca^2+] increase in CHSE cells.

Stage-specific change and regulation of endogenous protein phosphorylation in allomyces macrogynus: Park, Young Shik , Oh, Keun Hee , Lee, Soo Woong , Seong, Chang Soo , Park, I Ha , Yim, Jeong Bin; J. Microbiol. 1996;34(4):374-378.

34 View
0 Download

Abstract: In the aquatic fungus Allomyces macrogynus the effects of Ca^2+ and cAMP on the intracellular signal transduction of zeoospore germination were studied using in vitro protein phosphorylation assay system. An endogenuously phosphorylated protein (p50) having molecular weight of 50 kDa on SDS-PAGE was found in soluble fractions of both zeoospore and mycelium. In zoospore extract, the endogenous phophorylation of p50 was weak without any effectors, but was enhanced by Ca^2+ and even more by cAMP. Phosphorylation of the same protein in mycelial extract was high only in the absence of cAMP. Irrespective of the presence of Ca^2+ and cAMP, its phosphorylation was antagonistically suppressed in assay of combined zoospore and mycelial extracts. These results suggest that p50 is interconvertible in phosphorylation/dephosphorylation as a novel protein involved in germination of A. macrogynus. The antagonistic effect of cAMP to the phosphorylation of p50s from different developmental stages may be important in the regulation of cellular differentiation.

Purification and Properties of Novel Calcium-binding Proteins from Streptomyces coelicolor: Chang, Ji Hun , Yoon, Soon Sang , Lhee, Sang Moon , Park, I Ha , Jung, Do Young , Park, Yong Sik , Yim, Jeong Bin; J. Microbiol. 1999;37(1):21-26.

35 View
0 Download

Abstract: Two novel calcium-binding proteins, named CAB-I and CAB-II, have been isolated from Streptomyces coelicolor. Purification of the calcium-binding proteins involved heat treatment, fractionation with ammonium sulfate, acid treatment, anion exchange and hydrophobic interaction column chromatography, FPLC gel filtration, and preparative isoelectric focusing. A chelex competitive assay and ^45Ca autoradiography verified the calcium-binding ability of the proteins. The major band CAB-II has an apparent molecular weight of 26,000 determined by SDS-polyacrylamide gel electrophoresis and 340,000 determined by gel filtration. The isoelectric point of this molecule showed the acidic nature of the molecule. N-terminal amino acid sequence analysis shows homology to rat Ca^2+/calmodulin-dependent protein kinase-II (CAB-II) and yeast phosphoprotein phosphatase (CAB-I).

Induction of Apoptosis in Human Monocytes by Human Cytomegalovirus is Related with Calcium Increase: Myung Sook Moon , Gyu Cheol Lee , Chan H. Lee; J. Microbiol. 2002;40(3):224-229.

38 View
0 Download

Abstract: The effect of human cytomegalovirus (HCMV) on three human monocyte cell lines at different stages of differentiation was investigated. While the viability of HL-60 cells or U-937 cells was not significantly affected by HCMV infection, the viability of THP-1 cells was reduced. Acridine orange/ethidium bromide staining revealed that the reduction of THP-1 cell viability was due to increased apoptotic death following HCMV infection. Apoptosis in HL-60 cells was not affected by HCMV infection, and induction of apoptosis of U-937 cells by HCMV was intermediate between HL-60 and THP-1 cells. Since HL-60 cells are the least differentiated and THP-1 cells are the most differentiated, the induction of apoptosis of human monocytes appears to be related to the degree of cell differentiation. Flow cytometric and confocal microscopic studies using fluorescent calcium indicator Fluo-3 suggested a significant increase in intracellular free calcium concentration ([Ca^2+ ]_i ) in THP-1 cells undergoing apoptosis by HCMV infection. Again [Ca^2+ ]_i in HCMV-infected HL-60 cells was not critically altered, and that in HCMV-infected U-937 cells was intermediate between THP-1 cells and HL-60 cells. Calcium influx blockers such as verapamil and nifedipine partially reversed HCMV-induced apoptosis in THP-1 cells.

First
Prev
Page of 1
Next
Last

Search