MSK
Search
- Page Path
- HOME > Search
Full article
- Role of the LAMMER kinase LkhA in fungal development and aflatoxin production in Aspergillus flavus
- Seong-Hwan Jeong, He-Jin Cho, Jae-Hyuk Yu, Hee-Moon Park, Hee-Soo Park
- J. Microbiol. 2025;63(5):e2503007. Published online May 27, 2025
- DOI: https://doi.org/10.71150/jm.2503007
- 162 View
- 7 Download
-
Abstract
PDF -
A well-conserved LAMMER kinase in yeast and filamentous fungi, is a dual-specificity kinase with multiple roles in fungal biology. In this study, we assessed the roles of LkhA in Aspergillus flavus, a toxigenic fungus that produces aflatoxin B1. lkhA deletion mutants exhibited defects in fungal growth, conidiophore development, and sclerotia formation. These mutants exhibited impaired tolerance to oxidative and cell wall stresses. Moreover, the absence of lkhA resulted in a decrease in aflatoxin B1 production. The kernel assay revealed that the lkhA deletion mutants exhibited reduced production of conidia and aflatoxin B1, implying that LkhA can affect fungal toxigenesis and pathogenicity. Taken together, these results demonstrate that LkhA is important for differentiation, mycotoxin production, and pathogenicity in A. flavus.
Review
- Small regulatory RNAs as key modulators of antibiotic resistance in pathogenic bacteria
- Yubin Yang, Hana Hyeon, Minju Joo, Kangseok Lee, Eunkyoung Shin
- J. Microbiol. 2025;63(4):e2501027. Published online April 2, 2025
- DOI: https://doi.org/10.71150/jm.2501027
- 761 View
- 64 Download
-
Abstract
PDF
-
The escalating antibiotic resistance crisis poses a significant challenge to global public health, threatening the efficacy of current treatments and driving the emergence of multidrug-resistant pathogens. Among the various factors associated with bacterial antibiotic resistance, small regulatory RNAs (sRNAs) have emerged as pivotal post-transcriptional regulators which orchestrate bacterial adaptation to antibiotic pressure via diverse mechanisms. This review consolidates the current knowledge on sRNA-mediated mechanisms, focusing on drug uptake, drug efflux systems, lipopolysaccharides, cell wall modification, biofilm formation, and mutagenesis. Recent advances in transcriptomics and functional analyses have revealed novel sRNAs and their regulatory networks, expanding our understanding of resistance mechanisms. These findings highlight the potential of targeting sRNA-mediated pathways as an innovative therapeutic strategy to combat antibiotic resistance, and offer promising avenues for managing challenging bacterial infections.
Journal Article
- Flavobacterium psychrotrophum sp. nov. and Flavobacterium panacagri sp. nov., Isolated from Freshwater and Soil
- Yong-Seok Kim , Eun-Mi Hwang , Chang-Myeong Jeong , Chang-Jun Cha
- J. Microbiol. 2023;61(10):891-901. Published online October 18, 2023
- DOI: https://doi.org/10.1007/s12275-023-00081-1
- 98 View
- 0 Download
- 6 Web of Science
- 6 Crossref
-
Abstract
- Two novel bacterial strains CJ74T and CJ75T belonging to the genus Flavobacterium were isolated from freshwater of Han River and ginseng soil, South Korea, respectively. Strain CJ74T was Gram-stain-negative, aerobic, rod-shaped, non-motile, and non-flagellated, and did not produce flexirubin-type pigments. Strain CJ75T was Gram-stain-negative, aerobic, rodshaped, motile by gliding, and non-flagellated, and produced flexirubin-type pigments. Both strains were shown to grow optimally at 30 °C in the absence of NaCl on R2A medium. Phylogenetic analysis based on 16S rRNA gene sequences showed that strains CJ74T and CJ75T belonged to the genus Flavobacterium and were most closely related to Flavobacterium niveum TAPW14T and Flavobacterium foetidum CJ42T with 96.17% and 97.29% 16S rRNA sequence similarities, respectively. Genomic analyses including the reconstruction of phylogenomic tree, average nucleotide identity, and digital DNA-DNA hybridization suggested that they were novel species of the genus Flavobacterium. Both strains contained menaquinone 6 (MK-6) as the primary respiratory quinone and phosphatidylethanolamine as a major polar lipid. The predominant fatty acids of both strains were iso-C15:0 and summed feature 3 ( C16:1 ω7c and/or C16: 1 ω6c). Based on the polyphasic taxonomic study, strains CJ74T and CJ75T represent novel species of the genus Flavobacterium, for which names Flavobacterium psychrotrophum sp. nov. and Flavobacterium panacagri sp. nov. are proposed, respectively. The type strains are CJ74T (=KACC 19819T =JCM 32889T) and CJ75T (=KACC 23149T =JCM 36132T).
-
Citations
Citations to this article as recorded by
- Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation
Xu-Dong Lian, Yong Guan, Yue Jiang, Dong-Heui Kwak, Mi-Kyung Lee, Zhun Li
Scientific Reports.2025;[Epub] CrossRef - Ammonia-oxidizing activity and microbial structure of ammonia-oxidizing bacteria, ammonia-oxidizing archaea and complete ammonia oxidizers in biofilm systems with different salinities
Haojie Qiu, Weihua Zhao, Yingying Qin, Yanyan Wang, Meng Bai, Shaoqing Su, Chao Wang, Zhisheng Zhao
Bioresource Technology.2025; 423: 132248. CrossRef - mKmer: an unbiased K-mer embedding of microbiomic single-microbe RNA sequencing data
Fangyu Mo, Qinghong Qian, Xiaolin Lu, Dihuai Zheng, Wenjie Cai, Jie Yao, Hongyu Chen, Yujie Huang, Xiang Zhang, Sanling Wu, Yifei Shen, Yinqi Bai, Yongcheng Wang, Weiqin Jiang, Longjiang Fan
Briefings in Bioinformatics.2025;[Epub] CrossRef - Congregibacter variabilis sp. nov. and Congregibacter brevis sp. nov. Within the OM60/NOR5 Clade, Isolated from Seawater, and Emended Description of the Genus Congregibacter
Hyeonsu Tak, Miri S. Park, Hyerim Cho, Yeonjung Lim, Jang-Cheon Cho
Journal of Microbiology.2024; 62(9): 739. CrossRef - Flavobacterium rivulicola sp. nov., Isolated from a Freshwater Stream
Sumin Kim, Miri S. Park, Ilnam Kang, Jang-Cheon Cho
Current Microbiology.2024;[Epub] CrossRef - Validation List no. 218. Valid publication of new names and new combinations effectively published outside the IJSEM
Aharon Oren, Markus Göker
International Journal of Systematic and Evolutionary Microbiology .2024;[Epub] CrossRef
- Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation
Editorial
- Editorial] Bacterial Regulatory Mechanisms for the Control of Cellular Processes: Simple Organisms’ Complex Regulation
- Jin-Won Lee
- J. Microbiol. 2023;61(3):273-276. Published online April 3, 2023
- DOI: https://doi.org/10.1007/s12275-023-00036-6
- 107 View
- 0 Download
- 4 Web of Science
- 4 Crossref
-
Abstract
- Bacteria employ a diverse array of cellular regulatory mechanisms to successfully adapt and thrive in ever-changing environments, including but not limited to temperature changes, fluctuations in nutrient availability, the presence or absence of electron acceptors such as oxygen, the availability of metal ions crucial for enzyme activity, and the existence of antibiotics. Bacteria can virtually modulate any step of gene expression from transcr!ptional initiation to posttranslational modification of a protein for the control of cellular processes. Furthermore, one gene regulator often controls another in a complex gene regulatory network. Thus, it is not easy to fully understand the intricacies of bacterial regulatory mechanisms in various environments. In this special issue, while acknowledging the challenge of covering all aspects of bacterial regulatory mechanisms across diverse environments, seven review articles are included to provide insight into the recent progress in understanding such mechanisms from different perspectives: positive regulatory mechanisms by secondary messenger (cAMP receptor protein), two-component signal transduction mechanisms (Rcs and Cpx), diverse regulatory mechanisms by a specific environmental factor in specific bacteria (oxygen availability in Mycobacterium and manganese ion availability in Salmonella), diverse regulatory mechanisms by a specific environmental factor (temperature and antibiotics), and regulatory mechanisms by antibiotics in cell wall synthesis. Bacteria, as ubiquitous organisms that can be found in almost every environment, carry out complex cellular processes that allow them to survive and thrive in a variety of different conditions despite their small size and relative simplicity. One of the key factors that allows bacteria to carry out these complex processes is their ability to regulate gene expression through various mechanisms. Gene expression is a fundamental biological process by which the genetic information encoded in a gene is transcribed into an RNA molecule and subsequently translated into a functional gene product, often a protein. Furthermore, the activity levels of proteins may further be altered by posttranslational modification. Regulation of gene expression refers to the control of the amount and timing of gene expression, and thus it can be divided into transcr!ptional, translational, and posttranslational levels.
-
Citations
Citations to this article as recorded by- The PhoBR two-component system upregulates virulence in Aeromonas dhakensis C4–1
Wei Feng, Xuesong Li, Nuo Yang, Lixia Fan, Guiying Guo, Jun Xie, Xiuqing Cai, Yuqi Meng, Jifeng Zeng, Yu Han, Jiping Zheng
Aquaculture.2025; 595: 741665. CrossRef - Molecular mechanisms of cold stress response in cotton: Transcriptional reprogramming and genetic strategies for tolerance
Washu Dev, Fahmida Sultana, Hongge Li, Daowu Hu, Zhen Peng, Shoupu He, Haobo Zhang, Muhammad Waqas, Xiaoli Geng, Xiongming Du
Plant Science.2025; 352: 112390. CrossRef -
PhoPQ-mediated lipopolysaccharide modification governs intrinsic resistance to tetracycline and glycylcycline antibiotics in
Escherichia coli
Byoung Jun Choi, Umji Choi, Dae-Beom Ryu, Chang-Ro Lee, Mehrad Hamidian, You-Hee Cho
mSystems.2024;[Epub] CrossRef - Navigating the signaling landscape of Ralstonia solanacearum: a study of bacterial two-component systems
Mohit Yadav, Janhavi Sathe, Valentina Teronpi, Aditya Kumar
World Journal of Microbiology and Biotechnology.2024;[Epub] CrossRef
- The PhoBR two-component system upregulates virulence in Aeromonas dhakensis C4–1
Journal Articles
- Construction of high-density transposon mutant library of Staphylococcus aureus using bacteriophage ϕ11
- Wonsik Lee
- J. Microbiol. 2022;60(12):1123-1129. Published online November 24, 2022
- DOI: https://doi.org/10.1007/s12275-022-2476-2
- 78 View
- 0 Download
- 2 Web of Science
- 1 Crossref
-
Abstract
- Transposon mutant libraries are an important resource to study bacterial metabolism and pathogenesis. The fitness analysis of mutants in the libraries under various growth conditions provides important clues to study the physiology and biogenesis of structural components of a bacterial cell. A transposon library in conjunction with next-generation sequencing techniques, collectively named transposon sequencing (Tnseq), enables high-throughput genome profiling and synthetic lethality analysis. Tn-seq has also been used to identify essential genes and to study the mode of action of antibacterials. To construct a high-density transposon mutant library, an efficient delivery system for transposition in a model bacterium is essential. Here, I describe a detailed protocol for generating a high-density phage-based transposon mutant library in a Staphylococcus aureus strain, and this protocol is readily applicable to other S. aureus strains including USA300 and MW2.
-
Citations
Citations to this article as recorded by- Optimizing phage-based mutant recovery and minimizing heat effect in the construction of transposon libraries in Staphylococcus aureus
Sally W. Yousief, Nader Abdelmalek, Bianca Paglietti
Scientific Reports.2024;[Epub] CrossRef
- Optimizing phage-based mutant recovery and minimizing heat effect in the construction of transposon libraries in Staphylococcus aureus
- Correlation between fat accumulation and fecal microbiota in crossbred pigs
- Xin Li , Mengyu Li , Jinyi Han , Chuang Liu , Xuelei Han , Kejun Wang , Ruimin Qiao , Xiu-Ling Li , Xin-Jian Li
- J. Microbiol. 2022;60(11):1077-1085. Published online September 9, 2022
- DOI: https://doi.org/10.1007/s12275-022-2218-5
- 90 View
- 0 Download
- 4 Web of Science
- 3 Crossref
-
Abstract
- Backfat thickness (BF) is an important indicator of fat deposition capacity and lean meat rate in pigs and is very important in porcine genetics and breeding. Intestinal microbiota plays a key role in nutrient digestion and utilization with a profound impact on fat deposition of livestock animals. To investigate the relationship between the pig gut microbiome and BF, 20 low-BF (L-BF) and 20 high-BF (H-BF) pigs were selected as two groups from Yunong Black pigs in the present study. Fecal samples from pigs were analyzed for microbial diversity, composition, and predicted functionality using 16S rRNA gene sequencing. The results showed that there were significant differences in microbial β diversity between the two groups. LEfSe analysis revealed a number of bacterial features being differentially enriched in either L-BF or H-BF pigs. Spearman correlation analysis identified the abundance of Oscillospira, Peptococcus, and Bulleidia were significantly positive correlations with BF (P < 0.05), while Sutterella and Bifidobacterium were significantly negatively correlated with BF (P < 0.05). Importantly, the bacteria significantly positively correlated with BF mainly belong to Clostridium, which can ferment host-indigestible plant polysaccharides into shortchain fatty acid (SCFA) and promote fat synthesis and deposition. Predictive functional analysis indicated that the pathway abundance of cell motility and glycan biosynthesis were significantly widespread in the microbiota of the H-BF group. The results of this study will be useful for the development of microbial biomarkers for predicting and improving porcine BF, as well as for the investigation of targets for dietary strategies.
-
Citations
Citations to this article as recorded by- Carboxymethyl chitosan-dialdehyde glucan/polydopamine carrier targeted delivery Bacillus subtilis on enhancing oral utilization and intestinal colonization in mice
Lulu Chu, Luyu Xie, Bingzhi Chen, Yuji Jiang, Wenjie Wang
International Journal of Biological Macromolecules.2024; 280: 135574. CrossRef - Impact of Early Weaning on Development of the Swine Gut Microbiome
Benoit St-Pierre, Jorge Yair Perez Palencia, Ryan S. Samuel
Microorganisms.2023; 11(7): 1753. CrossRef - Comparison of Conjunctival Sac Microbiome between Low and High Myopic Eyes
Kang Xiao, Zhengyu Chen, Qin Long
Journal of Microbiology.2023; 61(5): 571. CrossRef
- Carboxymethyl chitosan-dialdehyde glucan/polydopamine carrier targeted delivery Bacillus subtilis on enhancing oral utilization and intestinal colonization in mice
- The novel antifungal agent AB-22 displays in vitro activity against hyphal growth and biofilm formation in Candida albicans and potency for treating systemic candidiasis
- Kyung-Tae Lee , Dong-Gi Lee , Ji Won Choi , Jong-Hyun Park , Ki Duk Park , Jong-Seung Lee , Yong-Sun Bahn
- J. Microbiol. 2022;60(4):438-443. Published online March 14, 2022
- DOI: https://doi.org/10.1007/s12275-022-2016-0
- 61 View
- 0 Download
- 2 Web of Science
- 1 Crossref
-
Abstract
- Systemic candidiasis, which is mainly caused by Candida albicans, is a serious acute fungal infection in the clinical setting. In a previous study, we reported that compound 22h (designated as AB-22 in this study), a vinyl sulfate compound, is a fast-acting fungicidal agent against a broad spectrum of fungal pathogens. In this study, we aimed to further analyze the in vitro and in vivo efficacy of AB-22 against filamentation, biofilm formation, and virulence of C. albicans. Under in vitro hyphal growth-inducing condition, AB-22 effectively inhibited germ tube formation and hyphal growth, which are required for the initiation of biofilm formation. Indeed, AB-22 significantly suppressed C. albicans biofilm formation in a dose-dependent manner. Moreover, AB-22 treatment inhibited the normal induction of ALS3, HWP1, and ECE1, which are all required for hyphal transition in C. albicans. Furthermore, AB-22 treatment increased the survival of mice systemically infected with C. albicans. In conclusion, in addition to its fungicidal activity, AB-22 inhibits filamentation and biofilm formation in C. albicans, which could collectively contribute to its potent in vivo efficacy against systemic candidiasis.
-
Citations
Citations to this article as recorded by- Preparation and analysis of quinoa active protein (QAP) and its mechanism of inhibiting Candida albicans from a transcriptome perspective
Xufei Zhang, Chunmei Zheng, Wenxuan Ge, Xueying Li, Xiuzhang Wang, Yanxia Sun, Xiaoyong Wu
PeerJ.2025; 13: e18961. CrossRef
- Preparation and analysis of quinoa active protein (QAP) and its mechanism of inhibiting Candida albicans from a transcriptome perspective
- Genetic diversity and population structure of the amylolytic yeast Saccharomycopsis fibuligera associated with Baijiu fermentation in China
- Ju-Wei Wang , Pei-Jie Han , Da-Yong Han , Sen Zhou , Kuan Li , Peng-Yu He , Pan Zhen , Hui-Xin Yu , Zhen-Rong Liang , Xue-Wei Wang , Feng-Yan Bai
- J. Microbiol. 2021;59(8):753-762. Published online July 5, 2021
- DOI: https://doi.org/10.1007/s12275-021-1115-7
- 58 View
- 0 Download
- 16 Web of Science
- 14 Crossref
-
Abstract
- The amylolytic yeast Saccharomycopsis fibuligera is a predominant species in starters and the early fermentation stage of Chinese liquor (Baijiu). However, the genetic diversity of the species remains largely unknown. Here we sequenced the genomes of 97 S. fibuligera strains from different Chinese Baijiu companies. The genetic diversity and population structure of the strains were analyzed based on 1,133 orthologous genes and the whole genome single nucleotide polymorphisms (SNPs). Four main lineages were recognized. One lineage contains 60 Chinese strains which are exclusively homozygous with relatively small genome sizes (18.55–18.72 Mb) and low sequence diversity. The strains clustered in the other three lineages are heterozygous with larger genomes (21.85–23.72 Mb) and higher sequence diversity. The genomes of the homozygous strains showed nearly 100% coverage with the genome of the reference strain KPH12 and the sub-genome A of the hybrid strain KJJ81 at the above 98% sequence identity level. The genomes of the heterozygous strains showed nearly 80% coverage with both the sub-genome A and the whole genome of KJJ81, suggesting that the Chinese heterozygous strains are also hybrids with nearly 20% genomes from an unidentified source. Eighty-three genes were found to show significant copy number variation between different lineages. However, remarkable lineage specific variations in glucoamylase and α-amylase activities and growth profiles in different carbon sources and under different environmental conditions were not observed, though strains exhibiting relatively high glucoamylase activity were mainly found from the homozygous lineage.
-
Citations
Citations to this article as recorded by- Isolation of Saccharomycopsis species from plant material
Carmen Dost, Florian Michling, Davies Kaimenyi, Mareike Rij, Jürgen Wendland
Microbiological Research.2024; 283: 127691. CrossRef - Microbial enzymes: the bridge between Daqu flavor and microbial communities
Zelong Zhong, Tianyi Liu, Kaiping He, Min Zhong, Xiaoxue Chen, Yansong Xue, Beizhong Han, Diqiang Wang, Jun Liu
Food Innovation and Advances.2024; 3(4): 426. CrossRef - Exploring the heterogeneity of community and function and correspondence of “species-enzymes” among three types of Daqu with different fermentation peak-temperature via high-throughput sequencing and metagenomics
Ying Huang, Dong Li, Yu Mu, Zhiyu Zhu, Yuzhang Wu, Qi Qi, Yingchun Mu, Wei Su
Food Research International.2024; 176: 113805. CrossRef - Deciphering the core microbes and their interactions in spontaneous Baijiu fermentation: A comprehensive review
Jiamu Kang, Xiaoning Huang, Rengshu Li, Yuandi Zhang, Xiao-Xue Chen, Bei-Zhong Han
Food Research International.2024; 188: 114497. CrossRef - Correlational analysis of physicochemical indexes, microbial communities, and volatile components in light-flavor Daqu from north and south regions of China
Qi Yu, Feiyan Mou, Junwen Xiao, Cheng Zhan, Liang Li, Xu Chang, Xiaoyuan Dong, Maobin Chen, Xinrui Wang, Mei Chen, Shangling Fang
World Journal of Microbiology and Biotechnology.2024;[Epub] CrossRef - Dynamic changes in volatile profiles and bacterial communities during natural fermentation of Mei yu, traditional Chinese fermented fish pieces
Hongmei Yin, Qiang Hong, Xiang Yu, Hui Wang, Xiaodan Shi, Wei Liu, Tao Yuan, Zongcai Tu
Food Research International.2024; 194: 114882. CrossRef - Exploring the relationship between GuaYi levels and microbial-metabolic dynamics in Daqu
Boyang Xu, Shanshan Xu, Hao Zhou, Ruijuan Wang, Chao Jiang, Dongdong Mu, Xuefeng Wu, Xiaolei Wu, Shaotong Jiang, Xingjiang Li
Food Bioscience.2024; 60: 104347. CrossRef - Exploring the Role of Active Functional Microbiota in Flavor Generation by Integrated Metatranscriptomics and Metabolomics during Niulanshan Baijiu Fermentation
Yuanyuan Pan, Ying Wang, Wenjun Hao, Sen Zhou, Chengbao Duan, Qiushi Li, Jinwang Wei, Gang Liu
Foods.2023; 12(22): 4140. CrossRef - Dynamic changes and correlations of microbial communities, physicochemical properties, and volatile metabolites during Daqu fermentation of Taorong-type Baijiu
Yanbo Liu, Haideng Li, Shumei Dong, Zhou Zhou, Zhenke Zhang, Runna Huang, Suna Han, Jianguang Hou, Chunmei Pan
LWT.2023; 173: 114290. CrossRef - The differences in carbohydrate utilization ability between six rounds of Sauce-flavor Daqu
Qi Zhu, Liangqiang Chen, Zheng Peng, Qiaoling Zhang, Wanqiu Huang, Fan Yang, Guocheng Du, Juan Zhang, Li Wang
Food Research International.2023; 163: 112184. CrossRef - Microbial Community Affects Daqu Quality and the Production of Ethanol and Flavor Compounds in Baijiu Fermentation
Pei-Jie Han, Lu-Jun Luo, Ying Han, Liang Song, Pan Zhen, Da-Yong Han, Yu-Hua Wei, Xin Zhou, Zhang Wen, Jun-Zhi Qiu, Feng-Yan Bai
Foods.2023; 12(15): 2936. CrossRef - Comparison of physicochemical characteristics and microbiome profiles of low-temperature Daqu with and without adding tartary buckwheat
Jiamu Kang, Liangliang Jia, Zhongxiao Zhang, Min Zhang, Xiaoning Huang, Xiaoxue Chen, Bei-Zhong Han
Food Bioscience.2022; 49: 101931. CrossRef - What Are the Main Factors That Affect the Flavor of Sauce-Aroma Baijiu
Jiao Niu, Shiqi Yang, Yi Shen, Wei Cheng, Hehe Li, Jinyuan Sun, Mingquan Huang, Baoguo Sun
Foods.2022; 11(21): 3534. CrossRef - Insights into the bacterial, fungal, and phage communities and volatile profiles in different types of Daqu
Jiamu Kang, Xiaoxue Chen, Bei-Zhong Han, Yansong Xue
Food Research International.2022; 158: 111488. CrossRef
- Isolation of Saccharomycopsis species from plant material
- Isolation of a novel strain, Sphingorhabdus sp. YGSMI21 and characterization of its enantioselective epoxide hydrolase activity
- Jung-Hee Woo , Hae-Seon Kim , Nyun-Ho Park , Ho Young Suk
- J. Microbiol. 2021;59(7):675-680. Published online June 1, 2021
- DOI: https://doi.org/10.1007/s12275-021-1023-x
- 73 View
- 0 Download
- 3 Web of Science
- 3 Crossref
-
Abstract
- Sphingorhabdus sp. YGSMI21, a novel microbial strain with an enantioselective epoxide hydrolase activity, was isolated from tidal samples contaminated by accidental oil spills subjected to enriched culture with polycyclic aromatic hydrocarbon. This strain was able to optically decompose (R)-styrene oxide (SO) and showed 100% optical purity. In addition, it showed a good enantioselectivity for the derivatives of (S)- SO, (S)-2-chlorostyrene oxide (CSO), (S)-3-CSO and (S)-4- CSO. For (S)-2-CSO, (S)-3-CSO and (S)-4-CSO, 99.9%ee was obtained with the yield of 26.2%, 24.8%, and 11.0%, respectively, when using 10 mg cells of Sphingorhabdus sp. YGSMI21 at pH 8.0 with 4 mM racemic substrates at pH 8.0 and 25°C. The values obtained in this study for (S)-2-CSO, particularly the yield of 26.2%, is noteworthy, considering that obtaining an enantiomerically pure form is difficult. Taken together, Sphingorhabdus sp. YGSMI21 can be regarded as a wholecell biocatalyst in the production of various (S)-CSO with the chlorine group at a different position.
-
Citations
Citations to this article as recorded by- Epoxide Hydrolases: Multipotential Biocatalysts
Marek Bučko, Katarína Kaniaková, Helena Hronská, Peter Gemeiner, Michal Rosenberg
International Journal of Molecular Sciences.2023; 24(8): 7334. CrossRef - Effects of submerged macrophytes (Elodea nuttallii) on water quality and microbial communities of largemouth bass (Micropterus salmoides) ponds
Zhijuan Nie, Zhaowei Zheng, Haojun Zhu, Yi Sun, Jun Gao, Jiancao Gao, Pao Xu, Gangchuan Xu
Frontiers in Microbiology.2023;[Epub] CrossRef - Description of Polaribacter batillariae sp. nov., Polaribacter cellanae sp. nov., and Polaribacter pectinis sp. nov., novel bacteria isolated from the gut of three types of South Korean shellfish
Su-Won Jeong, Jeong Eun Han, June-Young Lee, Ji-Ho Yoo, Do-Yeon Kim, In Chul Jeong, Jee-Won Choi, Yun-Seok Jeong, Jae-Yun Lee, So-Yeon Lee, Euon Jung Tak, Hojun Sung, Hyun Sik Kim, Pil Soo Kim, Dong-Wook Hyun, Jin-Woo Bae
Journal of Microbiology.2022; 60(6): 576. CrossRef
- Epoxide Hydrolases: Multipotential Biocatalysts
- Effect of biostimulation and bioaugmentation on hydrocarbon degradation and detoxification of diesel-contaminated soil: a microcosm study
- Patricia Giovanella , Lídia de Azevedo Duarte , Daniela Mayumi Kita , Valéria Maia de Oliveira , Lara Durães Sette
- J. Microbiol. 2021;59(7):634-643. Published online May 15, 2021
- DOI: https://doi.org/10.1007/s12275-021-0395-2
- 70 View
- 0 Download
- 6 Web of Science
- 7 Crossref
-
Abstract
- Soil contamination with diesel oil is quite common during processes of transport and storage. Bioremediation is considered a safe, economical, and environmentally friendly approach for contaminated soil treatment. In this context, studies using hydrocarbon bioremediation have focused on total petroleum hydrocarbon (TPH) analysis to assess process effectiveness, while ecotoxicity has been neglected. Thus, this study aimed to select a microbial consortium capable of detoxifying diesel oil and apply this consortium to the bioremediation of soil contaminated with this environmental pollutant through different bioremediation approaches. Gas chromatography (GC-FID) was used to analyze diesel oil degradation, while ecotoxicological bioassays with the bioindicators Artemia sp., Aliivibrio fischeri (Microtox), and Cucumis sativus were used to assess detoxification. After 90 days of bioremediation, we found that the biostimulation and biostimulation/ bioaugmentation approaches showed higher rates of diesel oil degradation in relation to natural attenuation (41.9 and 26.7%, respectively). Phytotoxicity increased in the biostimulation and biostimulation/bioaugmentation treatments during the degradation process, whereas in the Microtox test, the toxicity was the same in these treatments as that in the natural attenuation treatment. In both the phytotoxicity and Microtox tests, bioaugmentation treatment showed lower toxicity. However, compared with natural attenuation, this approach did not show satisfactory hydrocarbon degradation. Based on the microcosm experiments results, we conclude that a broader analysis of the success of bioremediation requires the performance of toxicity bioassays.
-
Citations
Citations to this article as recorded by- Heavy fuel oil-contaminated soil remediation by individual and bioaugmentation-assisted phytoremediation with Medicago sativa and with cold plasma-treated M. sativa
Jūratė Žaltauskaitė, Rimas Meištininkas, Austra Dikšaitytė, Laima Degutytė-Fomins, Vida Mildažienė, Zita Naučienė, Rasa Žūkienė, Kazunori Koga
Environmental Science and Pollution Research.2024; 31(20): 30026. CrossRef - Soil Corrosivity Under Natural Attenuation
Larissa O. da Silva, Sara H. de Oliveira, Rafael G. C. da Silva, Magda R. S. Vieira, Ivanilda R. de Melo, Severino L. Urtiga Filho
Materials Research.2024;[Epub] CrossRef - Updating risk remediation-endpoints for petroleum-contaminated soils? A case study in the Ecuadorian Amazon region
Daniel Hidalgo-Lasso, Karina García-Villacís, Jeaneth Urvina Ulloa, Darwin Marín Tapia, Patricio Gómez Ortega, Frederic Coulon
Heliyon.2024; 10(9): e30395. CrossRef - Recent advances in the development and applications of luminescent bacteria–based biosensors
Yingying Li, Yuankun Zhao, Yiyang Du, Xuechun Ren, He Ding, Zhimin Wang
Luminescence.2024;[Epub] CrossRef - Oil biodegradation studies with an immobilized bacterial consortium in plant biomass for the construction of bench-scale bioreactor
Rachel M. Ferreira, Bernardo D. Ribeiro, Danielle.M.A. Stapelfeldt, Rodrigo P. do Nascimento, Maria de.F.R. Moreira
Cleaner Chemical Engineering.2023; 6: 100107. CrossRef - Application of Luminescent Bacteria Bioassay in the Detection of Pollutants in Soil
Kai Zhang, Meng Liu, Xinlong Song, Dongyu Wang
Sustainability.2023; 15(9): 7351. CrossRef - Salicylate or Phthalate: The Main Intermediates in the Bacterial Degradation of Naphthalene
Vasili M. Travkin, Inna P. Solyanikova
Processes.2021; 9(11): 1862. CrossRef
- Heavy fuel oil-contaminated soil remediation by individual and bioaugmentation-assisted phytoremediation with Medicago sativa and with cold plasma-treated M. sativa
- Fungal diversity in deep-sea sediments from Magellan seamounts environment of the western Pacific revealed by high-throughput Illumina sequencing
- Shuai Yang , Wei Xu , Yuanhao Gao , Xiaoyao Chen , Zhu-Hua Luo
- J. Microbiol. 2020;58(10):841-852. Published online September 2, 2020
- DOI: https://doi.org/10.1007/s12275-020-0198-x
- 62 View
- 0 Download
- 15 Web of Science
- 15 Crossref
-
Abstract
- There are lots of seamounts globally whose primary production is disproportionally greater than the surrounding areas. Compared to other deep-sea environments, however, the seamounts environment is relatively less explored for fungal diversity. In the present study, we explored the fungal community structure in deep-sea sediments from four different stations of the Magellan seamounts environment by using high-throughput sequencing of the ITS1 region. A total of 1,897,618 ITS1 sequences were obtained. Among these sequences, fungal ITS1 sequences could be clustered into 1,662 OTUs. The majority of these sequences belonged to Ascomycota. In the genera level, the most abundant genus was Mortierella (4.79%), which was reported as a common fungal genus in soil and marine sediments, followed by Umbelopsis (3.80%), Cladosporium (2.98%), Saccharomycopsis (2.53%), Aspergillus (2.42%), Hortaea (2.36%), Saitozyma (2.20%), Trichoderma (2.12%), Penicillium (2.11%), Russula (1.86%), and Verticillium (1.40%). Most of these recovered genera belong to Ascomycota. The Bray-Curtis analysis showed that there was 37 to 85% dissimilarity of fungal communities between each two sediment samples. The Principal coordinates analysis clearly showed variations in the fungal community among different sediment samples. These results suggested that there was a difference in fungal community structures not only among four different sampling stations but also for different layers at the same station. The depth and geographical distance significantly affect the fungal community, and the effect of depth and geographical distance on the structure of the fungal community in the Magellan seamounts is basically same. Most of the fungi were more or less related to plants, these plant parasitic/symbiotic/endophytic fungi constitute a unique type of seamounts environmental fungal ecology, different from other marine ecosystems.
-
Citations
Citations to this article as recorded by- Biodiversity and community structures across the Magellan seamounts and abyssal plains in the western Pacific Ocean revealed by environmental DNA metabarcoding analysis
Eun-Bi Kim, Se-Jong Ju, Yeon Jee Suh
Frontiers in Marine Science.2024;[Epub] CrossRef - Multi-omics reveal wild habitat is more favorable for the metabolite accumulation in Astragalus mongolicus
Miaoyin Dong, Hongyan Su, Jinjuan Li, Dan Zhang, Wenzhi Yao, Delong Yang, Jianhe Wei, Mengfei Li, Paul W. Paré
Industrial Crops and Products.2024; 222: 119953. CrossRef - Geographical distribution and driving force of micro-eukaryotes in the seamount sediments along the island arc of the Yap and Mariana trenches
Yue Zhang, Hongbin Liu, Ning Huang, Xiaotong Peng, Hongmei Jing, Jing Han
Microbiology Spectrum.2023;[Epub] CrossRef - Succession of Fungal Community during Outdoor Deterioration of Round Bamboo
Xiaojiao An, Shuaibo Han, Xin Ren, John Sichone, Zhiwei Fan, Xinxing Wu, Yan Zhang, Hui Wang, Wei Cai, Fangli Sun
Journal of Fungi.2023; 9(6): 691. CrossRef - Depth-Dependent Distribution of Prokaryotes in Sediments of the Manganese Crust on Nazimov Guyots of the Magellan Seamounts
Jianxing Sun, Hongbo Zhou, Haina Cheng, Zhu Chen, Jichao Yang, Yuguang Wang, Chunlei Jing
Microbial Ecology.2023; 86(4): 3027. CrossRef - Ecological and Oceanographic Perspectives in Future Marine Fungal Taxonomy
Nalin N. Wijayawardene, Don-Qin Dai, Prabath K. Jayasinghe, Sudheera S. Gunasekara, Yuriko Nagano, Saowaluck Tibpromma, Nakarin Suwannarach, Nattawut Boonyuen
Journal of Fungi.2022; 8(11): 1141. CrossRef - Lignicolous freshwater fungi in Yunnan Province, China: an overview
Hong-Wei Shen, Dan-Feng Bao, Darbhe J. Bhat, Hong-Yan Su, Zong-Long Luo
Mycology.2022; 13(2): 119. CrossRef - Microbial diversity and community structure in deep-sea sediments of South Indian Ocean
Daochen Zhu, Sivasamy Sethupathy, Lu Gao, Muhammad Zohaib Nawaz, Weimin Zhang, Jianxiong Jiang, Jianzhong Sun
Environmental Science and Pollution Research.2022; 29(30): 45793. CrossRef - Marine Fungi: Opportunities and Challenges
Micael F. M. Gonçalves, Ana C. Esteves, Artur Alves
Encyclopedia.2022; 2(1): 559. CrossRef - Effects of Environmental Factors on Fungal Diversity and Composition in Coastal Sediments from Guangdong, China
Ke-Yue Wu, Yong-Chun Liu, Li Mo, Zu-Wang Sun, Zhi-Ying Liu, Zi-Hui Chen, Ri-Ming Huang, Xiaoyong Zhang
SSRN Electronic Journal .2022;[Epub] CrossRef - Fungal Diversity and Composition of the Continental Solar Saltern in Añana Salt Valley (Spain)
Maia Azpiazu-Muniozguren, Alba Perez, Aitor Rementeria, Irati Martinez-Malaxetxebarria, Rodrigo Alonso, Lorena Laorden, Javier Gamboa, Joseba Bikandi, Javier Garaizar, Ilargi Martinez-Ballesteros
Journal of Fungi.2021; 7(12): 1074. CrossRef - Bacterial and Fungal Diversity in Sediment and Water Column From the Abyssal Regions of the Indian Ocean
Natasha Maria Barnes, Samir R. Damare, Belle Damodara Shenoy
Frontiers in Marine Science.2021;[Epub] CrossRef - Diversity, Ecological Role and Biotechnological Potential of Antarctic Marine Fungi
Stefano Varrella, Giulio Barone, Michael Tangherlini, Eugenio Rastelli, Antonio Dell’Anno, Cinzia Corinaldesi
Journal of Fungi.2021; 7(5): 391. CrossRef - Patterns of Sediment Fungal Community Dependent on Farming Practices in Aquaculture Ponds
Zhimin Zhang, Qinghui Deng, Xiuyun Cao, Yiyong Zhou, Chunlei Song
Frontiers in Microbiology.2021;[Epub] CrossRef - Metabolic Potential, Ecology and Presence of Associated Bacteria Is Reflected in Genomic Diversity of Mucoromycotina
Anna Muszewska, Alicja Okrasińska, Kamil Steczkiewicz, Olga Drgas, Małgorzata Orłowska, Urszula Perlińska-Lenart, Tamara Aleksandrzak-Piekarczyk, Katarzyna Szatraj, Urszula Zielenkiewicz, Sebastian Piłsyk, Ewa Malc, Piotr Mieczkowski, Joanna S. Kruszewska
Frontiers in Microbiology.2021;[Epub] CrossRef
- Biodiversity and community structures across the Magellan seamounts and abyssal plains in the western Pacific Ocean revealed by environmental DNA metabarcoding analysis
- Short-term effects of returning granulated straw on soil microbial community and organic carbon fractions in dryland farming
- Wei Fan , Jinggui Wu
- J. Microbiol. 2020;58(8):657-667. Published online June 25, 2020
- DOI: https://doi.org/10.1007/s12275-020-9266-5
- 89 View
- 0 Download
- 30 Web of Science
- 29 Crossref
-
Abstract
- We conducted a 2-year field experiment which was comprised of five treatments, namely no straw returning (CK), straw mulching (SM), straw plowed into the soil (SP), and straw returned in granulated form (SG). The aim of this study was to investigate the effects of different straw returning modes on soil bacterial and fungal community structure and their relationships to soil organic carbon (SOC) fractions at three different soil depths (0–20, 20–40, and 40–60 cm) in a dryland under maize cultivation in Northeast (NE) China. SM, SP, and SG treatments significantly increased SOC content. Compared with SM and SP treatments, SG treatment significantly increased the content of SOC and easily oxidizable carbon (EOC) in the topsoil (0–20 cm depth), and increased dissolved organic carbon (DOC) and SOC content of the light fraction (LFOC) in the 20–40 cm layer. Meanwhile, SG treatment exhibited the highest microbial biomass C (MBC) content in all of the three soil depths. SG treatment also enhanced bacterial richness as well as fungal richness and diversity in the upper 40 cm of soil. In addition, SG treatment increased the relative abundance of Proteobacteria in all depths, and had the highest relative abundance of Basidiomycota in the first 20 cm of soil. SP treatment showed the lowest soil organic carbon content in all fractions and soil microbial community composition. SM treatment exhibited similar results to SG treatment in SOC, DOC, and LFOC contents, and bacterial diversity in the topsoil and subsoil. As a whole, treatment SG improved soil quality and maize yield, hence we recommend returning granulated straw as the most effective practice for enhancing labile SOC fractions as well as maintaining soil diversity and microbial richness of arid farmlands in NE China.
-
Citations
Citations to this article as recorded by- Evolutionary Behaviors of Straw-Reinforced Slurry for Sustainable Management of Dredging Sediment: Rheological and Fertility Properties
Chengchun Qiu, Liwei Xu, Weijuan Geng, Guizhong Xu, Dan Zhang
Waste and Biomass Valorization.2025; 16(3): 1057. CrossRef - Optimizing straw in rheology and compression–permeability of cemented dredged slurry
Guizhong Xu, Fahong Wu, Weijuan Geng
Marine Georesources & Geotechnology.2025; 43(5): 832. CrossRef - Metagenomic reconstruction of microbial structure and carbon cycling for annual crop productivity: influence of long-term straw mulching and nitrogen
Hongkun Yang, Qiaozheng Zou, Jiarui Zhang, Qian Xia, Xiaohong Ten, Xiulan Huang, Gaoqiong Fan
Applied Soil Ecology.2025; 211: 106146. CrossRef - Straw retention drives microbial community succession to improve soil C/N cycling: insights from a multi-year rice-based system
Shu Jia, Yue-Dong Li, Hang Qu, Bo Li, Ying-hua Juan, Yue-hua Xing, Yan Liu, Hong-jing Bao, Wen-tao Sun
Frontiers in Microbiology.2025;[Epub] CrossRef - Synergizing production and ecology: innovations in sustainable dryland agriculture
Xining Zhao, Honghua He, Kadambot H. M. Siddique, Xiaodong Gao
Plant and Soil.2024; 499(1-2): 1. CrossRef - Analysis of Tobacco Straw Return to the Field to Improve the Chemical, Physical, and Biological Soil Properties and Rice Yield
Jie Huang, Xinyue Wang, Lili Yang, Yuanhuan Li, Bing Xia, Hailin Li, Xiaohua Deng
Agronomy.2024; 14(5): 1025. CrossRef - Characteristics of Bacterial Communities under Different Tree Species and Their Response to Soil Physicochemical Properties
Zhe Chen, Suyan Li, Xiangyang Sun, Libing He, Wenzhi Zhou, Guanyu Zhao, Jiantao Yu, Xueting Bai, Jinshuo Zhang
Forests.2024; 15(5): 740. CrossRef - Effects of Different Straw Cover Patterns on Water Use Efficiency and Crop Growth
Han Lin, Mingyong Li, Jiangtao Ji, Chao Zhang, Guangyuan Zhong, Hongjian Wu, Zhaohui Du, Qianwen Li, Lu Tan, Haopeng Han
Agronomy.2024; 14(12): 2885. CrossRef - Successive Years of Rice Straw Return Increased the Rice Yield and Soil Nutrients While Decreasing the Greenhouse Gas Intensity
Meikang Wu, Min Nuo, Zixian Jiang, Ruiyao Xu, Hongcheng Zhang, Xiao Lu, Liqun Yao, Man Dou, Xu Xing, Xin Meng, Dongchao Wang, Xiaoshuang Wei, Ping Tian, Guan Wang, Zhihai Wu, Meiying Yang
Plants.2024; 13(17): 2446. CrossRef - Straw addition increases enzyme activities and microbial carbon metabolism activities in bauxite residue
Hao Wu, Wei Sun, Feng Zhu, Yifan Jiang, Shiwei Huang, Johnvie Goloran, Shengguo Xue
Journal of Environmental Sciences.2024; 135: 332. CrossRef - Impact of Straw Incorporation on the Physicochemical Profile and Fungal Ecology of Saline–Alkaline Soil
Weiming Ma, Li Ma, Jintang Jiao, Abbas Muhammad Fahim, Junyan Wu, Xiaolei Tao, Yintao Lian, Rong Li, Yapeng Li, Gang Yang, Lijun Liu, Yuanyuan Pu, Wancang Sun, Wangtian Wang
Microorganisms.2024; 12(2): 277. CrossRef - Different Impacts of Long-Term Tillage and Manure on Yield and N Use Efficiency, Soil Fertility, and Fungal Community in Rainfed Wheat in Loess Plateau
Mengni Chen, Hailiang Yang, Qingshan Yang, Yongshan Li, Hui Wang, Juanling Wang, Qiaolan Fan, Na Yang, Ke Wang, Jiancheng Zhang, Jiawei Yuan, Peng Dong, Lu Wang
Plants.2024; 13(24): 3477. CrossRef - Combined Application of Chemical and Organic Fertilizers Promoted Soil Carbon Sequestration and Bacterial Community Diversity in Dryland Wheat Fields
Hongmei Song, Zixuan Chang, Xuan Hu, Yan Li, Chengjiao Duan, Lifan Yang, Haoying Wang, Tingliang Li
Land.2024; 13(8): 1296. CrossRef - Continuous Straw Returning Combined with Nitrogen Application Improve Soil Properties and Yield of Double Cropping Maize in Subtropical Regions
Zhenwei Li, Kashif Khan, Li Yang, Yanqiong Pan, Xunbo Zhou
Sustainability.2024; 16(12): 5265. CrossRef - Changes in soil organic carbon and microbial community in saline soil following different forms of straw incorporation
Ting Fan, Yulin Zhang, Kexin Hu, Shiqi Xu, Afeng Zhang, Shaoqi Xue, Jiale Han, Xudong Wang
European Journal of Soil Science.2024;[Epub] CrossRef - Enhancing phosphorus transformation in typical reddish paddy soil from China: Insights on long-term straw return and pig manure application via microbial mechanisms
Jian Xiao, Jianglin Zhang, Peng Li, Youyun Tang, Yanhong Lu, Yulin Liao, Jun Nie
Science of The Total Environment.2024; 940: 173513. CrossRef - Effects of Maize Straw Return Modes on Soil Organic Carbon Content and Aggregate Stability in a Mollisol in Northeast China
Y. Yuan, H. Liu, Y. Liang, J. Yuan, C. Zhang, J. Zhang, H. Cai, L. Wang
Moscow University Soil Science Bulletin.2024; 79(5): 693. CrossRef - Deep Straw Burial Accelerates Straw Decomposition and Improves Soil Water Repellency
Bo-Yan Zhang, Sen Dou, Song Guan, Chuang Yang, Zhao Wang
Agronomy.2023; 13(7): 1927. CrossRef - Application of various high- density organic materials in soil promotes germination and increases nutrient content of wheat
Ting Fan, Yulin Zhang, Xudong Wang, Yonghua Zhao, Andong Shi, Xia Zhang
Environmental Technology & Innovation.2023; 32: 103298. CrossRef - Returned straw reduces nitrogen runoff loss by influencing nitrification process through modulating soil C:N of different paddy systems
Shaopeng Wang, Limei Zhai, Shufang Guo, Fulin Zhang, Lingling Hua, Hongbin Liu
Agriculture, Ecosystems & Environment.2023; 354: 108438. CrossRef - Effects of rumen microorganisms on straw returning to soil at different depths
Kailun Song, Chunhuo Zhou, Hengpei Li, Zicheng Zhou, Guorong Ni, Xin Yin
European Journal of Soil Biology.2023; 114: 103454. CrossRef - Stover return and nitrogen application affect soil organic carbon and nitrogen in a double‐season maize field
Y. X. Liu, Y. Q. Pan, L. Yang, S. Ahmad, X. B. Zhou, M. Zhou
Plant Biology.2022; 24(2): 387. CrossRef - Native soil organic-carbon contents shape distinct bacterial communities associated with priming effect
Xu Chen, Mengyang You, Xiaozeng Han, Xinchun Lu, Wenxiu Zou, Jun Yan
Pedobiologia.2022; 95: 150842. CrossRef - Straw Return and Nitrogen Fertilization to Maize Regulate Soil Properties, Microbial Community, and Enzyme Activities Under a Dual Cropping System
Li Yang, Ihsan Muhammad, Yu Xin Chi, Dan Wang, Xun Bo Zhou
Frontiers in Microbiology.2022;[Epub] CrossRef - Effect of straw application time on soil properties and microbial community in the Northeast China Plain
Liwei Wang, Cheng Wang, Fangyuan Feng, Zhengniu Wu, Hongkui Yan
Journal of Soils and Sediments.2021; 21(9): 3137. CrossRef - Labile organic carbon fractions drive soil microbial communities after long-term fertilization
Zhiming Zhang, Jun Yan, Xiaozeng Han, Wenxiu Zou, Xu Chen, Xinchun Lu, Yutian Feng
Global Ecology and Conservation.2021; 32: e01867. CrossRef - Soil bacterial community as impacted by addition of rice straw and biochar
Zhiqiang Tang, Liying Zhang, Na He, Diankai Gong, Hong Gao, Zuobin Ma, Liang Fu, Mingzhu Zhao, Hui Wang, Changhua Wang, Wenjing Zheng, Wenzhong Zhang
Scientific Reports.2021;[Epub] CrossRef - Straw incorporation plus biochar addition improved the soil quality index focused on enhancing crop yield and alleviating global warming potential
Na Li, Shuyue Wen, Shikun Wei, Hongyang Li, Yongzhong Feng, Guangxin Ren, Gaihe Yang, Xinhui Han, Xiaojiao Wang, Chengjie Ren
Environmental Technology & Innovation.2021; 21: 101316. CrossRef - Dynamics of soil bacteria and fungi communities of dry land for 8 years with soil conservation management
Yue Yang, Yan'an Tong, Lian-you Liang, Hong-chang Li, Wen-she Han
Journal of Environmental Management.2021; 299: 113544. CrossRef
- Evolutionary Behaviors of Straw-Reinforced Slurry for Sustainable Management of Dredging Sediment: Rheological and Fertility Properties
- Transcriptome analysis to understand the effects of the toxoflavin and tropolone produced by phytopathogenic Burkholderia on Escherichia coli
- Jungwook Park , Hyun-Hee Lee , Hyejung Jung , Young-Su Seo
- J. Microbiol. 2019;57(9):781-794. Published online August 27, 2019
- DOI: https://doi.org/10.1007/s12275-019-9330-1
- 79 View
- 0 Download
- 8 Web of Science
- 8 Crossref
-
Abstract
- The phytopathogenic Burkholderia species B. glumae and B. plantarii are the causal agents of bacterial wilt, grain rot, and seedling blight, which threaten the rice industry globally. Toxoflavin and tropolone are produced by these phytopathogens and are considered the most hostile biohazards with a broad spectrum of target organisms. However, despite their nonspecific toxicity, the effects of toxoflavin and tropolone on bacteria remain unknown. RNA-seq based transcriptome analysis was employed to determine the genome-wide expression patterns under phytotoxin treatment. Expression of 2327 and 830 genes was differentially changed by toxoflavin and tropolone, respectively. Enriched biological pathways reflected the down-regulation of oxidative phosphorylation and ribosome function, beginning with the inhibition of membrane biosynthesis and nitrogen metabolism under oxidative stress or iron starvation. Conversely, several systems such as bacterial chemotaxis, flagellar assembly, biofilm formation, and sulfur/taurine transporters were highly expressed as countermeasures against the phytotoxins. In addition, our findings revealed that three hub genes commonly induced by both phytotoxins function as the siderophore enterobactin, an ironchelator. Our study provides new insights into the effects of phytotoxins on bacteria for better understanding of the interactions between phytopathogens and other microorganisms. These data will also be applied as a valuable source in subsequent applications against phytotoxins, the major virulence factor.
-
Citations
Citations to this article as recorded by- AHL-Based Quorum Sensing Regulates the Biosynthesis of a Variety of Bioactive Molecules in Bacteria
Mélanie Gonzales, Pauline Jacquet, Floriane Gaucher, Éric Chabrière, Laure Plener, David Daudé
Journal of Natural Products.2024; 87(4): 1268. CrossRef - Determination of bacterial toxin toxoflavin and fervenulin in food and identification of their degradation products
Hui Wang, Lili Hu, Xiaotu Chang, Yuge Hu, Yan Zhang, Peng Zhou, Xiaojiao Cui
Food Chemistry.2023; 399: 134010. CrossRef - Antimicrobial peptides in combination with citronellal efficiently kills multidrug resistance bacteria
Zhanyi Yang, Shiqi He, Yingxin Wei, Xuefeng Li, Anshan Shan, Jiajun Wang
Phytomedicine.2023; 120: 155070. CrossRef - A membrane protein of the rice pathogen Burkholderia glumae required for oxalic acid secretion and quorum sensing
Asif Iqbal, George Nwokocha, Vijay Tiwari, Inderjit K. Barphagha, Anne Grove, Jong Hyun Ham, William T. Doerrler
Molecular Plant Pathology.2023; 24(11): 1400. CrossRef - Characterisation of Pythium aristosporum Oomycete—A Novel Pathogen Causing Rice Seedling Blight in China
Jinxin Liu, Ruisi Zhang, Chuzhen Xu, Chunlai Liu, Yanyan Zheng, Xue Zhang, Shasha Liu, Yonggang Li
Journal of Fungi.2022; 8(9): 890. CrossRef - Toxoflavin secreted by Pseudomonas alcaliphila inhibits the growth of Legionella pneumophila and Vermamoeba vermiformis
Sebastien P. Faucher, Sara Matthews, Arvin Nickzad, Passoret Vounba, Deeksha Shetty, Émilie Bédard, Michele Prévost, Eric Déziel, Kiran Paranjape
Water Research.2022; 216: 118328. CrossRef - Chemical or Genetic Alteration of Proton Motive Force Results in Loss of Virulence of Burkholderia glumae, the Cause of Rice Bacterial Panicle Blight
Asif Iqbal, Pradip R. Panta, John Ontoy, Jobelle Bruno, Jong Hyun Ham, William T. Doerrler, Gladys Alexandre
Applied and Environmental Microbiology.2021;[Epub] CrossRef - Multiple endogenous seed-born bacteria recovered rice growth disruption caused by Burkholderia glumae
Chiharu Akimoto-Tomiyama
Scientific Reports.2021;[Epub] CrossRef
- AHL-Based Quorum Sensing Regulates the Biosynthesis of a Variety of Bioactive Molecules in Bacteria
Review
- MINIREVIEW] The therapeutic applications of antimicrobial peptides (AMPs): a patent review
- Hee-Kyoung Kang , Cheolmin Kim , Chang Ho Seo , Yoonkyung Park
- J. Microbiol. 2017;55(1):1-12. Published online December 30, 2016
- DOI: https://doi.org/10.1007/s12275-017-6452-1
- 75 View
- 0 Download
- 282 Crossref
-
Abstract
- Antimicrobial peptides (AMPs) are small molecules with a broad spectrum of antibiotic activities against bacteria, yeasts, fungi, and viruses and cytotoxic activity on cancer cells, in addition to anti-inflammatory and immunomodulatory activities. Therefore, AMPs have garnered interest as novel therapeutic agents. Because of the rapid increase in drug-resistant pathogenic microorganisms, AMPs from synthetic and natural sources have been developed using alternative antimicrobial strategies. This article presents a broad analysis of patents referring to the therapeutic applications of AMPs since 2009. The review focuses on the universal trends in the effective design, mechanism, and biological evolution of AMPs.
-
Citations
Citations to this article as recorded by- Boc‐Protected Phenylalanine and Tryptophan‐Based Dipeptides: A Broad Spectrum Anti‐Bacterial Agent
Arpita Halder, Ravikumar Pasupuleti, Subramaniyam Sivagnanam, Priyadip Das, Oindrilla Mukherjee
Biopolymers.2025;[Epub] CrossRef - Detection of antibacterial peptides in artisanal rennet and evaluation of their antibacterial activity
Angela Michela Immacolata Montone, Sara Elsa Aita, Federico Capuano, Angelo Citro, Alessandra Esposito, Alfonso Gallo, Morena Nappa, Enrico Taglioni, Carmela Maria Montone
International Dairy Journal.2025; 160: 106074. CrossRef - Chiral nanosystem and chiral supraparticles for drug delivery: an expert opinion
Mahfoozur Rahman, Janhvi Singh, Alhussain Aodah, Majed Alrobaian, Nabil K Alruwaili, Waleed H Almalki, Salem Salman Almujri, Safia Obaidur Rab, Osama A. Madkhali, Ankit Sahoo, Jonathan A Lal
Expert Opinion on Drug Delivery.2025; 22(2): 143. CrossRef - Zeolitic imidazolium framework (ZIF-8) and their derivative-based material for antibacterial study: a comprehensive review
Asima Subhadarshini, Binita Nanda
Discover Materials.2025;[Epub] CrossRef - Comprehensive exploration of programmed cell death landscape in lung adenocarcinoma combining multi-omic analysis and experimental verification
Peng Yu, Leyang Xiao, Kaibo Hu, Jitao Ling, Yixuan Chen, Ruiqi Liang, Xinyu Liu, Deju Zhang, Yuzhen Liu, Tongchun Weng, Hongfa Jiang, Jing Zhang, Wuming Wang
Scientific Reports.2025;[Epub] CrossRef - Unfolding the Potential of Pyrrole- and Indole-Based Allylidene Hydrazine Carboximidamides as Antimicrobial Agents
Amit Sharma, Sonali J. Jain, Prabhat Nath Jha, Santosh Rudrawar, Sandip B. Bharate, Hemant R. Jadhav
ACS Infectious Diseases.2025; 11(2): 493. CrossRef - Exploring the potential of anticancer peptides as therapeutic agents for cancer treatment
Reza Ghavimi, Samira Mahmoudi, Mohsen Mohammadi, Elahe Khodamoradi, Ali Jahanian-Najafabadi
Research in Pharmaceutical Sciences.2025; 20(2): 165. CrossRef - Role of Milk-Derived Antimicrobial Peptides and their Future Perspectives in Pharmaceutical/ Dairy Industries
Venkateshwaran Krishnaswami, Selvakumar Muruganantham, Jacob Raja, Subhashini K Sripathi
Current Functional Foods.2025;[Epub] CrossRef - Nano-enhanced peptides: bridging cutting-edge tech and biology to
outsmart resilient microbes
Anurag Yadav, Kusum Yadav
Academia Nano: Science, Materials, Technology.2025;[Epub] CrossRef - The effect of C-terminal deamidation on bacterial susceptibility and resistance to modelin-5
Sarah R. Dennison, Leslie H. G. Morton, Kamal Badiani, Frederick Harris, David A. Phoenix
European Biophysics Journal.2025; 54(1-2): 45. CrossRef - Production, Delivery, and Regulatory Aspects for Application of Plant-Based Anti-microbial Peptides: a Comprehensive Review
Praveen Nagella, Balamuralikrishnan Balasubramanian, Sungkwon Park, Udisha Singh, Arpita Jayan, Saptadeepa Mukherjee, Aatika Nizam, Arun Meyyazhagan, Manikantan Pappuswamy, Joseph Kadanthottu Sebastian, Vasantha Veerappa Lakshmaiah, Amin Mousavi Khaneghah
Probiotics and Antimicrobial Proteins.2025;[Epub] CrossRef - Effect of Chirality and Amphiphilicity on the Antimicrobial Activity of Tripodal Lysine-Based Peptides
Anindyasundar Adak, Valeria Castelletto, Lucas de Mello, Bruno Mendes, Glyn Barrett, Jani Seitsonen, Ian W. Hamley
ACS Applied Bio Materials.2025; 8(1): 803. CrossRef - Recent advances, strategies, and future perspectives of peptide-based drugs in clinical applications
Qimeng Yang, Zhipeng Hu, Hongyu Jiang, Jialing Wang, Han Han, Wei Shi, Hai Qian
Chinese Journal of Natural Medicines.2025; 23(1): 31. CrossRef - Advance in peptide-based drug development: delivery platforms, therapeutics and vaccines
Wenjing Xiao, Wenjie Jiang, Zheng Chen, Yu Huang, Junyi Mao, Wei Zheng, Yonghe Hu, Jianyou Shi
Signal Transduction and Targeted Therapy.2025;[Epub] CrossRef - Small peptides from non-edible fish waste with antimicrobial activity
Benjamaporn Wonganu, Sittiruk Roytrakul, P. Jearanaisilawong, P. Srisungsitthisunti
E3S Web of Conferences.2025; 602: 02004. CrossRef - Green approaches for biofilm eradication: Enhancing cleaning efficiency
Samah Mechmechani, Piyush Kumar Jha, Layal Karam, Heni Dallagi
Journal of Food Safety.2024;[Epub] CrossRef - Combined release of LL37 peptide and zinc ion from a mussel-inspired coating on porous titanium for infected bone defect repairing
Yanni Zhang, Na Sun, Fangfang Hu, Wenhui Zhang, Qian Gao, Que Bai, Caiyun Zheng, Qiang Chen, Yong Han, Tingli Lu
Colloids and Surfaces B: Biointerfaces.2024; 244: 114181. CrossRef - Engineering Short Antimicrobial Peptides to Specifically Target Fusobacterium nucleatum in the Mixed Microbial Population
Zhao Liu, Yijie Wang, Chen Zhang, Yongshuai Yang, Junfeng Zhang
ACS Infectious Diseases.2024; 10(8): 3042. CrossRef - Novel non-helical antimicrobial peptides insert into and fuse lipid model membranes
Saheli Mitra, Bhairavi Chandersekhar, Yunshu Li, Mark Coopershlyak, Margot E. Mahoney, Brandt Evans, Rachel Koenig, Stephen C. L. Hall, Beate Klösgen, Frank Heinrich, Berthony Deslouches, Stephanie Tristram-Nagle
Soft Matter.2024; 20(20): 4088. CrossRef - Molecular characterization, antibacterial and immunoregulatory activities of liver-expressed antimicrobial peptide 2 in black rockfish, Sebastes schlegelii
Min Zhang, Xue Yan, Chang-biao Wang, Wen-qing Liu, Yue Wang, Hao Jing, Bing Wang, Kai Yang, Zi-yue Chen, Yu-yu Luan, Guang-hua Wang
Fish & Shellfish Immunology.2024; 147: 109467. CrossRef - Local Drug Delivery Systems as Novel Approach for Controlling NETosis in Periodontitis
Adina Bianca Boșca, Elena Dinte, Carmen Mihaela Mihu, Alina Elena Pârvu, Carmen Stanca Melincovici, Alina Simona Șovrea, Mariana Mărginean, Anne-Marie Constantin, Anida-Maria Băbțan, Alexandrina Muntean, Aranka Ilea
Pharmaceutics.2024; 16(9): 1175. CrossRef - Converging frontiers in cancer treatment: the role of nanomaterials, mesenchymal stem cells, and microbial agents—challenges and limitations
Hamed Afkhami, Aref Yarahmadi, Shoroq Bostani, Nahid Yarian, Mahdieh Sadat Haddad, Shima Sadat Lesani, Seyed Soheil Aghaei, Mohammad Reza Zolfaghari
Discover Oncology.2024;[Epub] CrossRef - Efficacy of a mouthwash containing ε-poly-L-lysine, funme peptides and domiphen in reducing halitosis and supragingival plaque: a randomized clinical trial
Song Shen, Xu Liu, Jun Huang, Yi Sun, Bin Liu, Wenzhu Song, Lei Meng, Mi Du, Qiang Feng
BMC Oral Health.2024;[Epub] CrossRef - Rational Design of Amphipathic Antimicrobial Peptides with Alternating L-/D-Amino Acids That Form Helical Structures
Motoharu Hirano, Hidetomo Yokoo, Nobumichi Ohoka, Takahito Ito, Takashi Misawa, Makoto Oba, Takao Inoue, Yosuke Demizu
Chemical and Pharmaceutical Bulletin.2024; 72(2): 149. CrossRef - Synthetic Antimicrobial Peptides Fail to Induce Leucocyte Innate Immune Functions but Elicit Opposing Transcriptomic Profiles in European Sea Bass and Gilthead Seabream
Laura Cervera, Elena Chaves-Pozo, Alberto Cuesta
Marine Drugs.2024; 22(2): 86. CrossRef - Three hepcidins from the spotted knifejaw (Oplegnathus punctatus) promote antimicrobial activity via TLR/NFκB pathway
Jie Wang, Yadong Chen, Yu Song, Wenteng Xu, Wensheng Li, Wenhui Ma, Chuanjun Yang, Zhangfan Chen, Songlin Chen
Fish & Shellfish Immunology.2024; 154: 109958. CrossRef - Combating antibiotic resistance in a one health context: a plethora of frontiers
Daniel Jesuwenu Ajose, Abimbola Olumide Adekanmbi, Nor Fadhilah Kamaruzzaman, Collins Njie Ateba, Shamsaldeen Ibrahim Saeed
One Health Outlook.2024;[Epub] CrossRef - A review on Diversity, Mechanism of Action and Evolutionary Significance of Antimicrobial Peptides
Noor Muhammad, Waiza Ansar, Arif Ullah, Iram Liaqat, Zahid Nazir
Futuristic Biotechnology.2024; : 02. CrossRef - Protective effects of Chinese bayberry pomace wine against oxidative stress on Drosophila melanogaster
Yanyun Zhu, Mengting Wang, Jingjing Zhu, Xiayin Zhang, Xingqian Ye, Jianchu Chen
Food Research International.2024; 194: 114885. CrossRef - In silico and physico-chemical characterization of cluster formation dynamics in peptide solutions
Dimitar Kaynarov, Karina Marinova, Rossitsa Marinova, Peicho Petkov, Lyudmila Velkova, Aleksandar Dolashki, Petar Petrov, Leandar Litov, Elena Lilkova, Pavlina Dolashka, Nevena Ilieva
Biochemistry and Biophysics Reports.2024; 39: 101753. CrossRef - Chensinin-1b Alleviates DSS-Induced Inflammatory Bowel Disease by Inducing Macrophage Switching from the M1 to the M2 Phenotype
Yue Sun, Huiyu Li, Xingpeng Duan, Xiaoxiao Ma, Chenxi Liu, Dejing Shang
Biomedicines.2024; 12(2): 345. CrossRef - Oral administration of anti-lipopolysaccharide factor isoform 3 via the bait microalga for controlling bacterial infection of Atlantic Bay scallop (Argopecten irradians)
Yulin Cui, Ping Liu, Yaping Shao, Fengjie Sun, Qiaolei Wang, Hao Zhang, Yan Cheng, Zhengquan Gao
Aquaculture Reports.2024; 39: 102430. CrossRef - Mechanistic insights on the antibiofilm potential of snake venom peptides: An in silico based molecular docking approach
Moupriya Nag
Biocatalysis and Agricultural Biotechnology.2024; 61: 103351. CrossRef - Antimicrobial Peptides and Their Biomedical Applications: A Review
Ki Ha Min, Koung Hee Kim, Mi-Ran Ki, Seung Pil Pack
Antibiotics.2024; 13(9): 794. CrossRef - Nano-strategies used for combatting the scourge of tuberculosis infections
Ren Fang, Yubao Jin, Weihao Kong, Hui Wang, Shuxian Wang, Xiaotian Li, Jiayin Xing, Yumiao Zhang, Xingyue Yang, Ningning Song
Discover Immunity.2024;[Epub] CrossRef - Antimicrobial Peptide Screening for Designing Custom Bactericidal Hydrogels
Matthias Recktenwald, Muskanjot Kaur, Mohammed M. Benmassaoud, Aryanna Copling, Tulika Khanna, Michael Curry, Dennise Cortes, Gilbert Fleischer, Valerie J. Carabetta, Sebastián L. Vega
Pharmaceutics.2024; 16(7): 860. CrossRef - Hepcidin and dicentracin peptides show preventive antiviral applications against NNV infection in European sea bass through immunomodulatory roles
Laura Cervera, Marta Arizcun, Luis Mercado, Elena Chaves-Pozo, Alberto Cuesta
Aquaculture.2024; 583: 740592. CrossRef - Natural Antimicrobial Peptides and Their Synthetic Analogues for Effective Oral Microflora Control and Oral Infection Treatment—The Role of Ceragenins in the Development of New Therapeutic Methods
Michał Czarnowski, Urszula Wnorowska, Milena Łuckiewicz, Ewelina Dargiewicz, Jakub Spałek, Sławomir Okła, Beata Sawczuk, Paul B. Savage, Robert Bucki, Ewelina Piktel
Pharmaceuticals.2024; 17(12): 1725. CrossRef - A Novel Beta-Defensin Isoform from Malabar Trevally, Carangoides malabaricus (Bloch & Schneider, 1801), an Arsenal Against Fish Bacterial Pathogens: Molecular Characterization, Recombinant Production, and Mechanism of Action
Athira P. P., Anju M. V., Anooja V. V., Archana K., Neelima S., Muhammed Musthafa S., I. S. Bright Singh, Rosamma Philip
Marine Biotechnology.2024; 26(4): 696. CrossRef - Daidzein‐Based Amphiphilic Small Molecular Antimicrobial Peptidomimetics as Novel Antimicrobial Agents with Anti‐Biofilm Activity
Zijian Hong, Tsz Tin Yu, Muhammad Yasir, Manjulatha Sara, David StC Black, Mark DP Willcox, Rajesh Kuppusamy, Naresh Kumar
ChemistrySelect.2024;[Epub] CrossRef - Development strategies and application of antimicrobial peptides as future alternatives to in-feed antibiotics
Qingping Liang, Zhemin Liu, Ziyu Liang, Changliang Zhu, Dongyu Li, Qing Kong, Haijin Mou
Science of The Total Environment.2024; 927: 172150. CrossRef - Functional interplay between short antimicrobial peptides and model lipid membranes
Lorena Gratino, Marta Gogliettino, Marco Balestrieri, Alessandra Porritiello, Principia Dardano, Bruno Miranda, Rosa Luisa Ambrosio, Monica Ambrosio, Luigi Nicolais, Gianna Palmieri
Bioorganic Chemistry.2024; 153: 107939. CrossRef - Improving Photocleavage Efficiency of Photocleavable Protein for
Antimicrobial Peptide Histatin 1 Expression
Nana Zhou, Tai An, Yuan Zhang, Guomiao Zhao, Chao Wei, Xuemei Shen, Fan Li, Xiaoyan Wang
Protein & Peptide Letters.2024; 31(2): 141. CrossRef -
In silico
approach revealed the membrane receptor PHO36 as a new target for synthetic anticandidal peptides
Francisco ES Lopes, Pedro FN Souza, Daiane MS Brito, Felipe P Mesquita, Raquel C Montenegro, Jackson L Amaral, José HA Filho, Valder N Freire, Rossana A Cordeiro
Future Microbiology.2024; 19(17): 1463. CrossRef - Interaction of designed cationic antimicrobial peptides with the outer membrane of gram-negative bacteria
Shelley He, Charles M. Deber
Scientific Reports.2024;[Epub] CrossRef - Artificial Intelligence-Based Model for Predicting the Minimum Inhibitory Concentration of Antibacterial Peptides Against ESKAPEE Pathogens
Ritesh Sharma, Sameer Shrivastava, Sanjay Kumar Singh, Abhinav Kumar, Amit Kumar Singh, Sonal Saxena
IEEE Journal of Biomedical and Health Informatics.2024; 28(4): 1949. CrossRef - Synergistic peptide combinations designed to suppress SARS-CoV-2
Tao Han, Linhong Song, Xinxin Niu, Meng Qiu, Yi Wang, Jing Wang, Xiuyan Sun, Jiali Ma, Siqi Hu, Zhichun Feng
Heliyon.2024; 10(9): e30489. CrossRef - Synthesis and Biological Studies of New Temporin A Analogs Containing Unnatural Amino Acids in Position 7
Dilyana Dimitrova, Veronica Nemska, Tsvetelina Foteva, Ivan Iliev, Nelly Georgieva, Dancho Danalev
Pharmaceutics.2024; 16(6): 716. CrossRef - PACAP sequence modifications modulate the peptide antimicrobial activity against bacterial pathogens affecting aquaculture
Laura Rivera Méndez, Tania Rodríguez-Cornejo, Tania Rodríguez-Ramos, Lowia Al-Hussinee, Janet Velázquez, James Hugh Campbell, Yamila Carpio, Mario Pablo Estrada, Brian Dixon
Fish & Shellfish Immunology.2024; 148: 109512. CrossRef - Antimicrobial and immunomodulatory activities of porcine cathelicidin Protegrin-1
Ali Javed, Trishana Oedairadjsingh, Irene S. Ludwig, Thomas M. Wood, Nathaniel I. Martin, Femke Broere, Markus H. Weingarth, Edwin J.A. Veldhuizen
Molecular Immunology.2024; 173: 100. CrossRef - Antimicrobial Peptides: Sources, Expression Systems, and Applications
Mengru Li, Weitao Lu, Yanyan Sun, Chunming Dong
Current Protein & Peptide Science.2023; 24(8): 640. CrossRef - Operative Management of Burns: Traditional Care
David G. Greenhalgh
European Burn Journal.2023; 4(2): 262. CrossRef - Antimicrobial Peptides
Noorul Samsoon Maharifa Haja Mohaideen, S. Vaani, S. Hemalatha
Current Pharmacology Reports.2023; 9(6): 433. CrossRef - Advances in Research on Titanium and Titanium Alloys with Antibacterial Functionality for Medical Use—A Review
Yong Shen, Zhankui Jin, Ming Ling, Zhengming Sun, Min Feng, Cuixiang Xu, Shizhang Liu
Journal of Biomaterials and Tissue Engineering.2023; 13(1): 1. CrossRef - An active domain SA-2 derived from cystatin-SA, and its antifungal activity
Xiaoyun Liu, Xiaowei Huang, Jian Wang, Meina Zhang, Mengyuan Liu, Changlin Zhou, Lingman Ma
Amino Acids.2023; 55(1): 101. CrossRef - Diversity of Bioinspired Hydrogels: From Structure to Applications
Alexandra Lupu, Luiza Madalina Gradinaru, Vasile Robert Gradinaru, Maria Bercea
Gels.2023; 9(5): 376. CrossRef - Bioactive peptides derived from fermented foods: Preparation and biological activities
Qingyan Guo, Pengfei Chen, Xianggui Chen
Journal of Functional Foods.2023; 101: 105422. CrossRef - Anti-microbial Peptides against Methicillin-resistant Staphylococcus
aureus: Promising Therapeutics
Priyanka Sinoliya, Pooran Singh Solanki, Sakshi Piplani, Ravi Ranjan Kumar Niraj, Vinay Sharma
Current Protein & Peptide Science.2023; 24(2): 156. CrossRef - Natural and synthetic peptides in antimicrobial therapy
Karina A. Khlystova, Narine G. Sarkisyan, Natalia N. Kataeva
Russian Journal of Immunology.2023; 26(2): 105. CrossRef - Biomimetic antimicrobial polymers—Design, characterization, antimicrobial, and novel applications
Haruko Takahashi, Iva Sovadinova, Kazuma Yasuhara, Satyavani Vemparala, Gregory A. Caputo, Kenichi Kuroda
WIREs Nanomedicine and Nanobiotechnology.2023;[Epub] CrossRef - Antimicrobial peptides: Structure, mechanism, and modification
Na Chen, Cheng Jiang
European Journal of Medicinal Chemistry.2023; 255: 115377. CrossRef - Repairing the intestinal mucosal barrier of traditional Chinese medicine for ulcerative colitis: a review
Yichen Zong, Jie Meng, Tangyou Mao, Qiang Han, Peng Zhang, Lei Shi
Frontiers in Pharmacology.2023;[Epub] CrossRef - Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides
Xiaofang Luo, Huifang Chen, Yannan Song, Zuodong Qin, Lijian Xu, Nongyue He, Yimin Tan, Wubliker Dessie
European Journal of Pharmaceutical Sciences.2023; 181: 106363. CrossRef - Therapeutic Prospection of Animal Venoms-Derived Antimicrobial Peptides against Infections by Multidrug-Resistant Acinetobacter baumannii: A Systematic Review of Pre-Clinical Studies
William Gustavo Lima, Maria Elena de Lima
Toxins.2023; 15(4): 268. CrossRef - Antimicrobial Efficacy and Prevalence of Microcins: Low Molecular Mass Bacteriocins Produced by Escherichia coli
Farzaneh Mohammadzadeh Rostami, Sharareh Moghim, Saeid Javdan, Bahram Nasr Esfahani
International Journal of Peptide Research and Therapeutics.2023;[Epub] CrossRef - Chiral-engineered supraparticles: Emerging tools for drug delivery
Mahfoozur Rahman, Waleed H. Almalki, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Shehla Nasar Mir Najib Ullah, Md. Abul Barkat, Sarwar Beg
Drug Discovery Today.2023; 28(1): 103420. CrossRef - In Vitro Biological Evaluation and Mechanism of Action of Peptoid Analogue Based on Cationic, Amphipathic Peptide A-12
Lalita Sharma, Gopal Singh Bisht
International Journal of Peptide Research and Therapeutics.2023;[Epub] CrossRef - Recombinant production of human antimicrobial peptide LL- 37 and its secondary structure
Antonín Pavelka, Lukáš Vacek, Adam Norek, Šárka Kobzová, Lubomír Janda
Biologia.2023; 79(1): 263. CrossRef - Synergistic Effect, Improved Cell Selectivity, and Elucidating the Action Mechanism of Antimicrobial Peptide YS12
Suzia Aktar Suchi, Dae Young Lee, Young Kyun Kim, Seong Soo Kang, Tahmina Bilkis, Jin Cheol Yoo
International Journal of Molecular Sciences.2023; 24(17): 13522. CrossRef - Dual-action potential of cationic cryptides against infections and cancers
Amr A.A. Abd El-Aal, Fairen A. Jayakumar, Kavita Reginald
Drug Discovery Today.2023; 28(11): 103764. CrossRef - Natural Amphibian-Derived Host Defense Peptides: Peptide Immunomodulators
with Potential Therapeutic Value
Jie Shi, Jing Wu, Guizhu Feng, Hailong Yang, Lixian Mu
Protein & Peptide Letters.2023; 30(7): 562. CrossRef - Self-assembled and Zn(II)-coordinated dipeptide nanoparticles with membrane-rupturing action on bacteria
Shahzad Anwar, Muhammad Babar Khawar, Ali Afzal, Muhammad Ovais, Zhang Xiang
Applied Microbiology and Biotechnology.2023; 107(18): 5775. CrossRef - Therapeutic Peptides for Treatment of Lung Diseases: Infection, Fibrosis, and Cancer
Shujiao Li, Yuying Li, Ying Liu, Yifan Wu, Qiuyu Wang, Lili Jin, Dianbao Zhang
International Journal of Molecular Sciences.2023; 24(10): 8642. CrossRef - The biological role of charge distribution in linear antimicrobial peptides
Harry Morales Duque, Gisele Rodrigues, Lucas Souza Santos, Octávio Luiz Franco
Expert Opinion on Drug Discovery.2023; 18(3): 287. CrossRef - Colitis-Mediated Dysbiosis of the Intestinal Flora and Impaired Vitamin A Absorption Reduce Ovarian Function in Mice
Ze Li, Chengzhen Chen, Wenjie Yu, Lingxia Xu, Haitao Jia, Chen Wang, Na Pei, Zibin Liu, Dan Luo, Jun Wang, Wenfa Lv, Bao Yuan, Jiabao Zhang, Hao Jiang
Nutrients.2023; 15(11): 2425. CrossRef - Insect Meals and Insect Antimicrobial Peptides as an Alternative for Antibiotics and Growth Promoters in Livestock Production
Ewelina Patyra, Krzysztof Kwiatek
Pathogens.2023; 12(6): 854. CrossRef - Simultaneous control of infection and inflammation with keratin-derived antibacterial peptides targeting TLRs and co-receptors
Yan Sun, Jonathan Chan, Karthikeyan Bose, Connie Tam
Science Translational Medicine.2023;[Epub] CrossRef - Structural Characterization, Functional Profiling, and Mechanism Study of Four Antimicrobial Peptides for Antibacterial and Anticancer Applications
Zihuayuan Yang, Jie Zhang, Fu-Gen Wu, Fengming Lin
Langmuir.2023; 39(6): 2161. CrossRef - Enhancement of hypericin nanoparticle-mediated sonoinduced disruption of biofilm and persister cells of Streptococcus mutans by dermcidin-derived peptide DCD-1L
Maryam Pourhajibagher, Steven Parker, Babak Pourakbari, Nasrin Keshavarz Valian, Reza Raoofian, Abbas Bahador
Photodiagnosis and Photodynamic Therapy.2023; 41: 103308. CrossRef - Biomimetic AgNPs@antimicrobial peptide/silk fibroin coating for infection-trigger antibacterial capability and enhanced osseointegration
Wenhao Zhou, Tian Bai, Lan Wang, Yan Cheng, Dandan Xia, Sen Yu, Yufeng Zheng
Bioactive Materials.2023; 20: 64. CrossRef - Preparation, Purification and Characterization of Antibacterial and ACE Inhibitory Peptides from Head Protein Hydrolysate of Kuruma Shrimp, Marsupenaeus japonicus
Jie Zhou, Qiuyu Han, Tomoyuki Koyama, Shoichiro Ishizaki
Molecules.2023; 28(2): 894. CrossRef - Brevicillin, a novel lanthipeptide from the genusBrevibacilluswith antimicrobial, antifungal, and antiviral activity
Shelley Sardul Singh, Deepika Sharma, Charandeep Singh, Sahil Kumar, Prashant Singh, Anshul Sharma, Deepjyoti Kumar Das, Anil Kumar Pinnaka, Krishan Gopal Thakur, Rajesh P Ringe, Suresh Korpole
Journal of Applied Microbiology.2023;[Epub] CrossRef - Fungicidal activity of human antimicrobial peptides and their synergistic interaction with common antifungals against multidrug-resistant Candida auris
Siham Shaban, Mrudula Patel, Aijaz Ahmad
International Microbiology.2022; 26(2): 165. CrossRef - Aptamer Decorated Emodin Nanoparticles-Assisted Delivery of Dermcidin-Derived Peptide DCD-1L: Photoactive Bio-Theragnostic Agent for Enterococcus Faecalis Biofilm Destruction
Maryam Pourhajibagher, Abbas Bahador
SSRN Electronic Journal .2022;[Epub] CrossRef - Aptamer decorated emodin nanoparticles-assisted delivery of dermcidin-derived peptide DCD-1L: Photoactive bio-theragnostic agent for Enterococcus faecalis biofilm destruction
Maryam Pourhajibagher, Abbas Bahador
Photodiagnosis and Photodynamic Therapy.2022; 39: 103020. CrossRef - Production of Antimicrobial Peptides (Cathelicidin Analogues) and Evaluation of Their Biological Properties
V. A. Gasanov, E. A. Vorotelyak, A. V. Vasiliev
Biology Bulletin.2022; 49(S2): S148. CrossRef - Progress in Alternative Strategies to Combat Antimicrobial Resistance: Focus on Antibiotics
Jayaseelan Murugaiyan, P. Anand Kumar, G. Srinivasa Rao, Katia Iskandar, Stephen Hawser, John P. Hays, Yara Mohsen, Saranya Adukkadukkam, Wireko Andrew Awuah, Ruiz Alvarez Maria Jose, Nanono Sylvia, Esther Patience Nansubuga, Bruno Tilocca, Paola Roncada,
Antibiotics.2022; 11(2): 200. CrossRef - Strategies for improving antimicrobial peptide production
Soumya Deo, Kristi L. Turton, Tajinder Kainth, Ayush Kumar, Hans-Joachim Wieden
Biotechnology Advances.2022; 59: 107968. CrossRef - Riemerella anatipestifer T9SS Effector SspA Functions in Bacterial Virulence and Defending Natural Host Immunity
Zongchao Chen, Pengfei Niu, Xiaomei Ren, Wenlong Han, Ruyu Shen, Min Zhu, Yang Yu, Chan Ding, Shengqing Yu, Martha Vives
Applied and Environmental Microbiology.2022;[Epub] CrossRef - Antibacterial and Antibiofilm Activities of Novel Cyclic Peptides against Methicillin-Resistant Staphylococcus aureus
Guoxing Wei, Yun He
International Journal of Molecular Sciences.2022; 23(14): 8029. CrossRef - Effect of Flagellin Pre-Exposure on the Inflammatory and Antifungal Response of Bronchial Epithelial Cells to Fungal Pathogens
Jeanne Bigot, Manon Ruffin, Juliette Guitard, Sandra Vellaissamy, Sophie Thorez, Harriet Corvol, Loïc Guillot, Viviane Balloy, Christophe Hennequin
Journal of Fungi.2022; 8(12): 1268. CrossRef - Gold nanoparticle-DNA aptamer-assisted delivery of antimicrobial peptide effectively inhibits Acinetobacter baumannii infection in mice
Jaeyeong Park, Eunkyoung Shin, Ji-Hyun Yeom, Younkyung Choi, Minju Joo, Minho Lee, Je Hyeong Kim, Jeehyeon Bae, Kangseok Lee
Journal of Microbiology.2022; 60(1): 128. CrossRef - Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds
Mine Erdem Büyükkiraz, Zülal Kesmen
Journal of Applied Microbiology.2022; 132(3): 1573. CrossRef - Novel Insights into Fungal Infections Prophylaxis and Treatment in Pediatric Patients with Cancer
Gianluca Bossù, Riccardo Di Sario, Edoardo Muratore, Davide Leardini, Andrea Pession, Susanna Esposito, Riccardo Masetti
Antibiotics.2022; 11(10): 1316. CrossRef - Pathogen-Specific Bactericidal Method Mediated by Conjugative Delivery of CRISPR-Cas13a Targeting Bacterial Endogenous Transcripts
Zihao Song, Yue Yu, Xinpeng Bai, Yiguo Jia, Jiayi Tian, Kui Gu, Mengyu Zhao, Changyu Zhou, Xiangyu Zhang, Hongning Wang, Yizhi Tang, Sandeep Tamber
Microbiology Spectrum.2022;[Epub] CrossRef - Role of lipopolysaccharide in antimicrobial and cell penetrating peptide membrane interactions probed by deuterium NMR of whole cells
Sarika Kumari, Michael R. Morrow, Valerie Booth
BBA Advances.2022; 2: 100057. CrossRef - Multidrug-Resistant Microbial Therapy Using Antimicrobial Peptides and the CRISPR/Cas9 System
Yared Abate Getahun, Destaw Asfaw Ali, Bihonegn Wodajnew Taye, Yismaw Alemie Alemayehu
Veterinary Medicine: Research and Reports.2022; Volume 13: 173. CrossRef - Pulmonary surfactant and drug delivery: Vehiculization of a tryptophan-tagged antimicrobial peptide over the air-liquid interfacial highway
Cristina García-Mouton, Elisa Parra-Ortiz, Martin Malmsten, Antonio Cruz, Jesús Pérez-Gil
European Journal of Pharmaceutics and Biopharmaceutics.2022; 180: 33. CrossRef - Production of antimicrobial peptide arasin-like Sp in Escherichia coli via an ELP-intein self-cleavage system
Xiu Li, Yu Jiang, Ying Lin
Journal of Biotechnology.2022; 347: 49. CrossRef - Review and perspective on bioactive peptides: A roadmap for research, development, and future opportunities
Zhenjiao Du, Yonghui Li
Journal of Agriculture and Food Research.2022; 9: 100353. CrossRef - Human Antimicrobial Peptide Triggered Colloidal Transformations in Bacteria Membrane Lipopolysaccharides
Linda Hong, Mark Gontsarik, Heinz Amenitsch, Stefan Salentinig
Small.2022;[Epub] CrossRef - Combination of Six Individual Derivatives of the Pom-1 Antibiofilm Peptide Doubles Their Efficacy against Invasive and Multi-Resistant Clinical Isolates of the Pathogenic Yeast Candida albicans
Michelle Häring, Valerie Amann, Ann-Kathrin Kissmann, Tilmann Herberger, Christopher Synatschke, Nicole Kirsch-Pietz, Julio A. Perez-Erviti, Anselmo J. Otero-Gonzalez, Fidel Morales-Vicente, Jakob Andersson, Tanja Weil, Steffen Stenger, Armando Rodríguez,
Pharmaceutics.2022; 14(7): 1332. CrossRef - Pathophysiological Effects of Lycosa erythrognatha Derived Peptide LyeTxI-b on RKO-AS-45-1 Colorectal Carcinoma Cell Line Using the Chicken Chorioallantoic Membrane Model
Carolina Nunes da Silva, Lays Fernanda Nunes Dourado, Luciana Maria Silva, Aline Brito de Lima, Maria Elena de Lima, Armando Silva-Cunha, Silvia Ligório Fialho
International Journal of Peptide Research and Therapeutics.2022;[Epub] CrossRef - Effect of a monovalent salt on the energetics of an antimicrobial-peptide: micelle dissociation
Suvankar Ghosh, Sunanda Chatterjee, Priyadarshi Satpati
Physical Chemistry Chemical Physics.2022; 24(38): 23669. CrossRef - Synthetic Amphipathic β-Sheet Temporin-Derived Peptide with Dual Antibacterial and Anti-Inflammatory Activities
Rosa Bellavita, Elisabetta Buommino, Bruno Casciaro, Francesco Merlino, Floriana Cappiello, Noemi Marigliano, Anella Saviano, Francesco Maione, Rosaria Santangelo, Maria Luisa Mangoni, Stefania Galdiero, Paolo Grieco, Annarita Falanga
Antibiotics.2022; 11(10): 1285. CrossRef - Effect of Leu/Val Mutation on the Energetics of Antimicrobial Peptide:Micelle Binding
Suvankar Ghosh, Sunanda Chatterjee, Priyadarshi Satpati
The Journal of Physical Chemistry B.2022; 126(28): 5262. CrossRef - Alternatives Therapeutic Approaches to Conventional Antibiotics: Advantages, Limitations and Potential Application in Medicine
Hiba Alaoui Mdarhri, Rachid Benmessaoud, Houda Yacoubi, Lina Seffar, Houda Guennouni Assimi, Mouhsine Hamam, Rihabe Boussettine, Najoie Filali-Ansari, Fatima Azzahra Lahlou, Idrissa Diawara, Moulay Mustapha Ennaji, Mohamed Kettani-Halabi
Antibiotics.2022; 11(12): 1826. CrossRef - Antimicrobial peptides: natural or synthetic defense peptides against HBV and HCV infections
Masoud Keikha, Hossein Kamali, Kiarash Ghazvini, Mohsen Karbalaei
VirusDisease.2022; 33(4): 445. CrossRef - Immune Activated Cellular Therapy for Drug Resistant Infections: Rationale, Mechanisms, and Implications for Veterinary Medicine
Lynn M. Pezzanite, Lyndah Chow, Alyssa Strumpf, Valerie Johnson, Steven W. Dow
Veterinary Sciences.2022; 9(11): 610. CrossRef - In Vitro Antibacterial Effects of the Chimeric Peptides from Chicken and Pig Antimicrobial Peptide NK-Lysin
Yeojin Hong, Gi Yong Lee, Soo-Jin Yang, Hyun Soon Lillehoj, Yeong Ho Hong
Korean Journal of Poultry Science.2022; 49(2): 69. CrossRef - High Level Expression and Purification of Cecropin-like Antimicrobial Peptides in Escherichia coli
Chih-Lung Wu, Ya-Han Chih, Hsin-Ying Hsieh, Kuang-Li Peng, Yi-Zong Lee, Bak-Sau Yip, Shih-Che Sue, Jya-Wei Cheng
Biomedicines.2022; 10(6): 1351. CrossRef - The antimicrobial peptides LL-37, KR-20, FK-13 and KR-12 inhibit the growth of a sensitive and a metronidazole-resistant strain of Trichomonas vaginalis
María G. Ramírez-Ledesma, Mayra C. Rodríguez, Nayeli Alva-Murillo, Eva E. Avila
Parasitology Research.2022; 121(12): 3503. CrossRef - Fabrication of an Antimicrobial Peptide-Loaded Silk Fibroin/Gelatin Bilayer Sponge to Apply as a Wound Dressing; An In Vitro Study
Milad Chizari, Sadjad Khosravimelal, Hamid Tebyaniyan, Mehrdad Moosazadeh Moghaddam, Mazaher Gholipourmalekabadi
International Journal of Peptide Research and Therapeutics.2022;[Epub] CrossRef - Interaction of a short antimicrobial peptide on charged lipid bilayer: A case study on aurein 1.2 peptide
Shuo Qian, Piotr A. Zolnierczuk
BBA Advances.2022; 2: 100045. CrossRef - The Role of Intestinal Mucosal Barrier in Autoimmune Disease: A Potential Target
Jia An, Yuqing Liu, Yiqi Wang, Ru Fan, Xiaorong Hu, Fen Zhang, Jinhua Yang, Junwei Chen
Frontiers in Immunology.2022;[Epub] CrossRef - Effect of C‐terminal and N‐terminal dimerization and alanine scanning on antibacterial activity of the analogs of the peptide p‐BthTX‐I
Norival Alves Santos‐Filho, Gabriela Marinho Righetto, Marina Rodrigues Pereira, Julia Pinto Piccoli, Larissa Mathias Teizen Almeida, Thainá Cristina Leal, Ilana Lopes Baratella Cunha Camargo, Eduardo Maffud Cilli
Peptide Science.2022;[Epub] CrossRef - Ramosin: The First Antibacterial Peptide Identified on Bolitoglossa ramosi Colombian Salamander
Laura Medina, Fanny Guzmán, Claudio Álvarez, Jean Paul Delgado, Belfran Carbonell-M
Pharmaceutics.2022; 14(12): 2579. CrossRef - Bioactive Antimicrobial Peptides: A New Weapon to Counteract Zoonosis
Luisa Zupin, Carlos André dos Santos-Silva, Aya R. Hamad Al Mughrbi, Livia Maria Batista Vilela, Ana Maria Benko-Iseppon, Sergio Crovella
Microorganisms.2022; 10(8): 1591. CrossRef - Antimicrobial Peptide Mechanisms Studied by Whole-Cell Deuterium NMR
Sarika Kumari, Valerie Booth
International Journal of Molecular Sciences.2022; 23(5): 2740. CrossRef - In silico screening and characterization of novel natural peptides as spike protein inhibitors of novel coronavirus (severe acute respiratory syndrome coronavirus 2)
Raghunath Satpathy, Namrata Dash
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine.2022; 1(1): 54. CrossRef - Key Physicochemical Determinants in the Antimicrobial Peptide RiLK1 Promote Amphipathic Structures
Lucia Falcigno, Gabriella D’Auria, Gianna Palmieri, Marta Gogliettino, Bruna Agrillo, Rosarita Tatè, Principia Dardano, Luigi Nicolais, Marco Balestrieri
International Journal of Molecular Sciences.2021; 22(18): 10011. CrossRef - Cytotoxicity and antimicrobial activity of synthetic peptides alone or in combination with conventional antimicrobials against fish pathogenic bacteria
I.M. Assane, N.A. Santos‐Filho, E.L. Sousa, M.C.O. Arruda Brasil, E.M. Cilli, F. Pilarski
Journal of Applied Microbiology.2021; 131(4): 1762. CrossRef - Integrating Porphyrinic Metal-Organic Frameworks in Nanofibrous Carrier for Photodynamic Antimicrobial Application
Huiru Zhang, Zhihao Xu, Ying Mao, Yingjie Zhang, Yan Li, Jihong Lao, Lu Wang
Polymers.2021; 13(22): 3942. CrossRef - Metal–Organic-Framework-Based Materials for Antimicrobial Applications
Rui Li, Tongtong Chen, Xiangliang Pan
ACS Nano.2021; 15(3): 3808. CrossRef - Polyphenylglyoxamide-Based Amphiphilic Small Molecular Peptidomimetics as Antibacterial Agents with Anti-Biofilm Activity
Tsz Tin Yu, Rajesh Kuppusamy, Muhammad Yasir, Md. Musfizur Hassan, Manjulatha Sara, Junming Ho, Mark D. P. Willcox, David StC. Black, Naresh Kumar
International Journal of Molecular Sciences.2021; 22(14): 7344. CrossRef - Initial purification of antimicrobial fermentation metabolites from Paecilomyces cicadae and its antimicrobial mechanism
Qi-Wen Cen, Zheng-Yun Wang, Zhen-Xing Tang, Yu Zhang, Tao Chen, Da-Wei Xue, Ming-Feng Xu, Xue-Lian Bai, Ting Zhou, Lu-E Shi
LWT.2021; 148: 111785. CrossRef - Deep-ABPpred: identifying antibacterial peptides in protein sequences using bidirectional LSTM with word2vec
Ritesh Sharma, Sameer Shrivastava, Sanjay Kumar Singh, Abhinav Kumar, Sonal Saxena, Raj Kumar Singh
Briefings in Bioinformatics.2021;[Epub] CrossRef - Cutaneous Neuroimmune Interactions in Peripheral Neuropathic Pain States
Daniel B. Lowy, Preet G. S. Makker, Gila Moalem-Taylor
Frontiers in Immunology.2021;[Epub] CrossRef - New Perspectives on Old and New Therapies of Staphylococcal Skin Infections: The Role of Biofilm Targeting in Wound Healing
Oriana Simonetti, Giulio Rizzetto, Giulia Radi, Elisa Molinelli, Oscar Cirioni, Andrea Giacometti, Annamaria Offidani
Antibiotics.2021; 10(11): 1377. CrossRef - Antimicrobial peptides: mechanism of action, activity and clinical potential
Qi-Yu Zhang, Zhi-Bin Yan, Yue-Ming Meng, Xiang-Yu Hong, Gang Shao, Jun-Jie Ma, Xu-Rui Cheng, Jun Liu, Jian Kang, Cai-Yun Fu
Military Medical Research.2021;[Epub] CrossRef - Trends in peptide drug discovery
Markus Muttenthaler, Glenn F. King, David J. Adams, Paul F. Alewood
Nature Reviews Drug Discovery.2021; 20(4): 309. CrossRef - Atomic-engineering Au-Ag nanoalloys for screening antimicrobial agents with low toxicity towards mammalian cells
Zi Lin, Yao Luo, Pengfei Liu, Yanjun Li, Jun Yue, Lelun Jiang
Colloids and Surfaces B: Biointerfaces.2021; 204: 111831. CrossRef - Discovery, Optimization, and Clinical Application of Natural Antimicrobial Peptides
Armando A. Rodríguez, Anselmo Otero-González, Maretchia Ghattas, Ludger Ständker
Biomedicines.2021; 9(10): 1381. CrossRef - Expression of antimicrobial peptide Cecropin P1 in Saccharomyces cerevisiae and its antibacterial and antiviral activity in vitro
Ruijiao Jiang, Pengfei Zhang, Xulong Wu, Yin Wang, Tayyab Rehman, Xueping Yao, Yan Luo, Zexiao Yang
Electronic Journal of Biotechnology.2021; 50: 16. CrossRef - Structure–activity relationship study of amphipathic antimicrobial peptides using helix‐destabilizing sarcosine
Hidetomo Yokoo, Motoharu Hirano, Nobumichi Ohoka, Takashi Misawa, Yosuke Demizu
Journal of Peptide Science.2021;[Epub] CrossRef - The barrier beyond the skin
Elisa MOLITERNI, Giovanni PAOLINO, Antonio G. RICHETTA, Sara GRASSI, Stefano CALVIERI
Italian Journal of Dermatology and Venereology.2021;[Epub] CrossRef - Plant Antimicrobial Peptides as Potential Tool for Topic Treatment of Hidradenitis Suppurativa
Carlos André dos Santos-Silva, Paola Maura Tricarico, Lívia Maria Batista Vilela, Ricardo Salas Roldan-Filho, Vinícius Costa Amador, Adamo Pio d’Adamo, Mireli de Santana Rêgo, Ana Maria Benko-Iseppon, Sergio Crovella
Frontiers in Microbiology.2021;[Epub] CrossRef - Short communication: Algicide activity of antimicrobial peptides compounds against Prototheca bovis
V.R. Sperotto, L.B. Denardi, C. Weiblen, F.P.K. de Jesus, M.R. Dorneles, L.B. Ianiski, J.M. Santurio
Journal of Dairy Science.2021; 104(3): 3554. CrossRef - β-Defensins from common goby (Pomatoschistus microps) and silver trevally (Pseudocaranx georgianus): Molecular characterization and phylogenetic analysis
K. L. Dhanya Lenin, Rajeswary Vasu Iyer, Athira Raveendran, M. V. Anju, Rosamma Philip, Swapna P. Antony
Molecular Biology Reports.2021; 48(5): 4943. CrossRef - Impact of the Peptide WMR-K on Dual-Species Biofilm Candida albicans/Klebsiella pneumoniae and on the Untargeted Metabolomic Profile
Emilia Galdiero, Maria Michela Salvatore, Angela Maione, Federica Carraturo, Stefania Galdiero, Annarita Falanga, Anna Andolfi, Francesco Salvatore, Marco Guida
Pathogens.2021; 10(2): 214. CrossRef - Peptides and Dendrimers: How to Combat Viral and Bacterial Infections
Annarita Falanga, Valentina Del Genio, Stefania Galdiero
Pharmaceutics.2021; 13(1): 101. CrossRef - Antimicrobial peptides and their application in food packaging
Yaowen Liu, Dur E. Sameen, Saeed Ahmed, Jianwu Dai, Wen Qin
Trends in Food Science & Technology.2021; 112: 471. CrossRef - Mechanistic Understanding from Molecular Dynamics in Pharmaceutical Research 2: Lipid Membrane in Drug Design
Tomasz Róg, Mykhailo Girych, Alex Bunker
Pharmaceuticals.2021; 14(10): 1062. CrossRef - Structural Diversity using Hyp “Customizable Units”: Proof‐of‐Concept Synthesis of Sansalvamide‐Related Antitumoral Peptides
Fernando Cuevas, Carlos J. Saavedra, Ivan Romero‐Estudillo, Alicia Boto, Mario Ordóñez, Irene Vergara
European Journal of Organic Chemistry.2021; 2021(6): 933. CrossRef - Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm‐Associated Infections
Stella Cascioferro, Daniela Carbone, Barbara Parrino, Camilla Pecoraro, Elisa Giovannetti, Girolamo Cirrincione, Patrizia Diana
ChemMedChem.2021; 16(1): 65. CrossRef - Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides
Shelley He, Tracy A. Stone, Charles M. Deber
Biochemistry.2021; 60(34): 2586. CrossRef - Preferential binding affinity of ions and their effect on structure and dynamics of water near antimicrobial peptide
Omkar Singh, Debashree Chakraborty
Journal of Molecular Liquids.2021; 344: 117789. CrossRef - Synthesis and Antibacterial Activity of Cationic Amino Acid-Conjugated Dendrimers Loaded with a Mixture of Two Triterpenoid Acids
Anna Maria Schito, Gian Carlo Schito, Silvana Alfei
Polymers.2021; 13(4): 521. CrossRef - Recent Advances and Challenges in Nanodelivery Systems for Antimicrobial Peptides (AMPs)
Ziyan Tang, Quantao Ma, Xiaoling Chen, Tianbao Chen, Yuan Ying, Xinping Xi, Lei Wang, Chengbang Ma, Chris Shaw, Mei Zhou
Antibiotics.2021; 10(8): 990. CrossRef - Rediscovery of antimicrobial peptides as therapeutic agents
Minkyung Ryu, Jaeyeong Park, Ji-Hyun Yeom, Minju Joo, Kangseok Lee
Journal of Microbiology.2021; 59(2): 113. CrossRef - Microfluidic Tools for Enhanced Characterization of Therapeutic Stem Cells and Prediction of Their Potential Antimicrobial Secretome
Pasquale Marrazzo, Valeria Pizzuti, Silvia Zia, Azzurra Sargenti, Daniele Gazzola, Barbara Roda, Laura Bonsi, Francesco Alviano
Antibiotics.2021; 10(7): 750. CrossRef - Chiral self-assembly of peptides: Toward the design of supramolecular polymers with enhanced chemical and biological functions
Yuhe Shen, Yuefei Wang, Ian W. Hamley, Wei Qi, Rongxin Su, Zhimin He
Progress in Polymer Science.2021; 123: 101469. CrossRef - Amphiphilic polymer therapeutics: an alternative platform in the fight against antibiotic resistant bacteria
Haruko Takahashi, Gregory A. Caputo, Kenichi Kuroda
Biomaterials Science.2021; 9(8): 2758. CrossRef - Self-Assembly Pathways and Antimicrobial Properties of Lysozyme in Different Aggregation States
Nico Kummer, Tingting Wu, Kevin J. De France, Flavia Zuber, Qun Ren, Peter Fischer, Silvia Campioni, Gustav Nyström
Biomacromolecules.2021; 22(10): 4327. CrossRef - Effect of Non-natural Hydrophobic Amino Acids on the Efficacy and Properties of the Antimicrobial Peptide C18G
Morgan A. Hitchner, Matthew R. Necelis, Devanie Shirley, Gregory A. Caputo
Probiotics and Antimicrobial Proteins.2021; 13(2): 527. CrossRef - Apoptosis-induction effect of ε-poly-lysine against Staphylococcus aureus and its application on pasteurized milk
Hou-Qi Ning, Ying-Qiu Li, Hong Lin, Jing-Xue Wang
LWT.2021; 137: 110493. CrossRef - Marine Invertebrate Peptides: Antimicrobial Peptides
Ran Wu, Jiri Patocka, Eugenie Nepovimova, Patrik Oleksak, Martin Valis, Wenda Wu, Kamil Kuca
Frontiers in Microbiology.2021;[Epub] CrossRef - Generation of antimicrobial peptides Leg1 and Leg2 from chickpea storage protein, active against food spoilage bacteria and foodborne pathogens
Marie-Louise Heymich, Ulrike Friedlein, Marius Trollmann, Karin Schwaiger, Rainer A. Böckmann, Monika Pischetsrieder
Food Chemistry.2021; 347: 128917. CrossRef - Alternative Therapeutic Interventions: Antimicrobial Peptides and Small Molecules to Treat Microbial Keratitis
Praveen Kumar Jadi, Prerana Sharma, Bharathi Bhogapurapu, Sanhita Roy
Frontiers in Chemistry.2021;[Epub] CrossRef - His-Rich Peptides, Gly- and His-Rich Peptides: Functionally Versatile Compounds with Potential Multi-Purpose Applications
Luiz G. P. Nunes, Thais Reichert, M. Teresa Machini
International Journal of Peptide Research and Therapeutics.2021; 27(4): 2945. CrossRef - Effect of monovalent salt concentration and peptide secondary structure in peptide-micelle binding
Suvankar Ghosh, Gopal Pandit, Swapna Debnath, Sunanda Chatterjee, Priyadarshi Satpati
RSC Advances.2021; 11(58): 36836. CrossRef - Polyalanine peptide variations may have different mechanisms of action against multidrug-resistant bacterial pathogens
Mário R Felício, Gislaine G O S Silveira, Karen G N Oshiro, Beatriz T Meneguetti, Octávio L Franco, Nuno C Santos, Sónia Gonçalves
Journal of Antimicrobial Chemotherapy.2021; 76(5): 1174. CrossRef - Challenge in the Discovery of New Drugs: Antimicrobial Peptides against WHO-List of Critical and High-Priority Bacteria
Cesar Augusto Roque-Borda, Patricia Bento da Silva, Mosar Corrêa Rodrigues, Ricardo Bentes Azevedo, Leonardo Di Filippo, Jonatas L. Duarte, Marlus Chorilli, Eduardo Festozo Vicente, Fernando Rogério Pavan
Pharmaceutics.2021; 13(6): 773. CrossRef - Natural and Synthetic Halogenated Amino Acids—Structural and Bioactive Features in Antimicrobial Peptides and Peptidomimetics
Mario Mardirossian, Marina Rubini, Mauro F. A. Adamo, Marco Scocchi, Michele Saviano, Alessandro Tossi, Renato Gennaro, Andrea Caporale
Molecules.2021; 26(23): 7401. CrossRef - Alleviation of DSS-induced colitisvia Lactobacillus acidophilustreatment in mice
Woon-Ki Kim, Dae Hee Han, You Jin Jang, SungJun Park, Sung Jae Jang, Giljae Lee, Hyuk Seung Han, GwangPyo Ko
Food & Function.2021; 12(1): 340. CrossRef - Antibacterial activity of antimicrobial peptide-conjugated nanofibrous membranes
Günnur Onak, Utku Kürşat Ercan, Ozan Karaman
Biomedical Materials.2021; 16(1): 015020. CrossRef - Stability and Activity of the Antimicrobial Peptide Leg1 in Solution and on Meat and Its Optimized Generation from Chickpea Storage Protein
Marie-Louise Heymich, Showmika Srirangan, Monika Pischetsrieder
Foods.2021; 10(6): 1192. CrossRef - Is it time to reconsider prophylactic antimicrobial use for hematopoietic stem cell transplantation? a narrative review of antimicrobials in stem cell transplantation
Dilshad Jahan, Ed Peile, Md Arif Sheikh, Salequl Islam, Sharlene Parasnath, Paras Sharma, Katia Iskandar, Sameer Dhingra, Jaykaran Charan, Timothy Craig Hardcastle, Nandeeta Samad, Tajkera Sultana Chowdhury, Siddhartha Dutta, Mainul Haque
Expert Review of Anti-infective Therapy.2021; 19(10): 1259. CrossRef - Identifying the Potential Therapeutic Targets for Atopic Dermatitis Through the Immune Infiltration Analysis and Construction of a ceRNA Network
Shixiong Peng, Mengjiao Chen, Ming Yin, Hao Feng
Clinical, Cosmetic and Investigational Dermatology.2021; Volume 14: 437. CrossRef - A novel apidaecin Api-PR19 synergizes with the gut microbial community to maintain intestinal health and promote growth performance of broilers
Shengru Wu, Jian Wang, Liqin Zhu, Hao Ren, Xiaojun Yang
Journal of Animal Science and Biotechnology.2020;[Epub] CrossRef - Dietary effects of antimicrobial peptides in therapeutics
Olalekan Olanrewaju Bakare, Adewale Oluwaseun Fadaka, Ashwil Klein, Ashley Pretorius
All Life.2020; 13(1): 78. CrossRef - Characterization, Cytotoxic Analysis and Action Mechanism of Antilisterial Bacteriocin Produced by Lactobacillus plantarum Isolated from Cheddar Cheese
Fariha Ibrahim, Nadir Naveed Siddiqui, Afsheen Aman, Shah Ali Ul Qader, Asma Ansari
International Journal of Peptide Research and Therapeutics.2020; 26(4): 1751. CrossRef - Positively Charged Polymers as Promising Devices against Multidrug Resistant Gram-Negative Bacteria: A Review
Silvana Alfei, Anna Maria Schito
Polymers.2020; 12(5): 1195. CrossRef - Effects of Peptide Thanatin on the Growth and Transcriptome of Penicillium digitatum
Guirong Feng, Xindan Li, Wenjun Wang, Lili Deng, Kaifang Zeng
Frontiers in Microbiology.2020;[Epub] CrossRef - A novel in silico antimicrobial peptide DP7 combats MDR Pseudomonas aeruginosa and related biofilm infections
Qi Yin, Siwen Wu, Lei Wu, Zhenling Wang, Yandong Mu, Rui Zhang, Chunyan Dong, Bailing Zhou, Binyan Zhao, Jiajun Zheng, Ying Sun, Xingjun Cheng, Li Yang
Journal of Antimicrobial Chemotherapy.2020; 75(11): 3248. CrossRef - β-defensins and the inflammatory periodontal diseases: a systematic review
E. A. Tikhomirova, E. S. Slazhneva, V. G. Atrushkevich
Parodontologiya.2020; 25(4): 276. CrossRef - Strategies to Combat Multidrug-Resistant and Persistent Infectious Diseases
Olga Pacios, Lucia Blasco, Inès Bleriot, Laura Fernandez-Garcia, Mónica González Bardanca, Antón Ambroa, María López, German Bou, Maria Tomás
Antibiotics.2020; 9(2): 65. CrossRef - Ultra-Short Antimicrobial Peptoids Show Propensity for Membrane Activity Against Multi-Drug Resistant Mycobacterium tuberculosis
Jasmeet Singh Khara, Biljana Mojsoska, Devika Mukherjee, Paul R. Langford, Brian D. Robertson, Håvard Jenssen, Pui Lai Rachel Ee, Sandra M. Newton
Frontiers in Microbiology.2020;[Epub] CrossRef - Scorpion-Venom-Derived Antimicrobial Peptide Css54 Exerts Potent Antimicrobial Activity by Disrupting Bacterial Membrane of Zoonotic Bacteria
Jonggwan Park, Jun Hee Oh, Hee Kyoung Kang, Moon-Chang Choi, Chang Ho Seo, Yoonkyung Park
Antibiotics.2020; 9(11): 831. CrossRef - Cationic amphipathic peptide analogs of cathelicidin LL‐37 as a probe in the development of antimicrobial/anticancer agents
Athanasios Tzitzilis, Anastasia Boura‐Theodorou, Vassilios Michail, Stylianos Papadopoulos, Dimitrios Krikorian, Marilena E. Lekka, Anna‐Irini Koukkou, Maria Sakarellos‐Daitsiotis, Eugenia Panou‐Pomonis
Journal of Peptide Science.2020;[Epub] CrossRef - Antimicrobial Peptides from Rat-Tailed Maggots of the Drone Fly Eristalis tenax Show Potent Activity against Multidrug-Resistant Gram-Negative Bacteria
Rolf Hirsch, Jochen Wiesner, Armin Bauer, Alexander Marker, Heiko Vogel, Peter Eugen Hammann, Andreas Vilcinskas
Microorganisms.2020; 8(5): 626. CrossRef - The protective and pathogenic roles of CXCL17 in human health and disease: Potential in respiratory medicine
José Alberto Choreño-Parra, Shyamala Thirunavukkarasu, Joaquín Zúñiga, Shabaana A. Khader
Cytokine & Growth Factor Reviews.2020; 53: 53. CrossRef - The global preclinical antibacterial pipeline
Ursula Theuretzbacher, Kevin Outterson, Aleks Engel, Anders Karlén
Nature Reviews Microbiology.2020; 18(5): 275. CrossRef - Combating Implant Infections: Shifting Focus from Bacteria to Host
Saber Amin Yavari, Suzanne M. Castenmiller, Jos A. G. van Strijp, Michiel Croes
Advanced Materials.2020;[Epub] CrossRef - Identification of two carcinin isoforms (MnCarc1 and MnCarc2) and their function in the antimicrobial immunity of Macrobrachium nipponense
Xiaoling Dai, Kaiqiang Wang, Ruidong Zhang, Chao Zhang, Xueying Cao, Xin Huang, Yufei Zhang, Qian Ren
Fish & Shellfish Immunology.2020; 106: 205. CrossRef - Antimicrobial Peptides: a New Frontier in Antifungal Therapy
Giuseppe Buda De Cesare, Shane A. Cristy, Danielle A. Garsin, Michael C. Lorenz, J. Andrew Alspaugh
mBio.2020;[Epub] CrossRef - Lactoferrin Functionalized Biomaterials: Tools for Prevention of Implant-Associated Infections
Emoke Pall, Alexandra Roman
Antibiotics.2020; 9(8): 522. CrossRef - Immunopathogenesis of COVID-19 and early immunomodulators
Kyung-Yil Lee, Jung-Woo Rhim, Jin-Han Kang
Clinical and Experimental Pediatrics.2020; 63(7): 239. CrossRef - Analysis of mutations of defensin protein using accelerated molecular dynamics simulations
Bharati Pandey, Chetna Tyagi, Gopal Kumar Prajapati, Awdhesh Kumar Mishra, Abeer Hashem, Abdulaziz A. Alqarawi, Elsayed Fathi Abd_Allah, Tapan Kumar Mohanta, Ayyalusamy Ramamoorthy
PLOS ONE.2020; 15(11): e0241679. CrossRef - Bronchial Epithelial Cells on the Front Line to Fight Lung Infection-Causing Aspergillus fumigatus
Jeanne Bigot, Loïc Guillot, Juliette Guitard, Manon Ruffin, Harriet Corvol, Viviane Balloy, Christophe Hennequin
Frontiers in Immunology.2020;[Epub] CrossRef - Neutrophil Extracellular Traps in Periodontitis
Antonio Magán-Fernández, Sarmad Muayad Rasheed Al-Bakri, Francisco O’Valle, Cristina Benavides-Reyes, Francisco Abadía-Molina, Francisco Mesa
Cells.2020; 9(6): 1494. CrossRef - Salmonid Antibacterial Immunity: An Aquaculture Perspective
Shawna L. Semple, Brian Dixon
Biology.2020; 9(10): 331. CrossRef - Polymeric and inorganic nanoscopical antimicrobial fillers in dentistry
Pooyan Makvandi, Jun Ting Gu, Ehsan Nazarzadeh Zare, Behnaz Ashtari, Arash Moeini, Franklin R. Tay, Li-na Niu
Acta Biomaterialia.2020; 101: 69. CrossRef - Multidrug Resistance (MDR) and Collateral Sensitivity in Bacteria, with Special Attention to Genetic and Evolutionary Aspects and to the Perspectives of Antimicrobial Peptides—A Review
András Fodor, Birhan Addisie Abate, Péter Deák, László Fodor, Ervin Gyenge, Michael G. Klein, Zsuzsanna Koncz, Josephat Muvevi, László Ötvös, Gyöngyi Székely, Dávid Vozik, László Makrai
Pathogens.2020; 9(7): 522. CrossRef - Assessing the effectiveness of AS-48 in experimental mice models of Chagas’ disease
Rubén Martín-Escolano, Rubén Cebrián, Mercedes Maqueda, Desirée Romero, Maria José Rosales, Manuel Sánchez-Moreno, Clotilde Marín
Journal of Antimicrobial Chemotherapy.2020; 75(6): 1537. CrossRef - Nanostructured antimicrobial peptides: The last push towards clinics
Jose Vicente Carratalá, Naroa Serna, Antonio Villaverde, Esther Vázquez, Neus Ferrer-Miralles
Biotechnology Advances.2020; 44: 107603. CrossRef - Functional peptide-based drug delivery systems
Zheng Lian, Tianjiao Ji
Journal of Materials Chemistry B.2020; 8(31): 6517. CrossRef - Gel Chromatographic Fractionation of Metabolic Complexes of L. rhamnosus GG and S. boulardii and their Antimicrobial Activity
O. Isaуenko, E. Babych , T. Gorbach, O. Semenchenko, O. Kotsar
Ukraïnsʹkij žurnal medicini, bìologìï ta sportu.2020; 5(4): 240. CrossRef - Antibacterial Activity of Non-Cytotoxic, Amino Acid-Modified Polycationic Dendrimers against Pseudomonas aeruginosa and Other Non-Fermenting Gram-Negative Bacteria
Anna Maria Schito, Silvana Alfei
Polymers.2020; 12(8): 1818. CrossRef - Antimicrobial activity of Ib-M peptides against Escherichia coli O157: H7
Sergio Prada-Prada, Johanna Flórez-Castillo, Ana Farfán-García, Fanny Guzmán, Indira Hernández-Peñaranda, Iddya Karunasagar
PLOS ONE.2020; 15(2): e0229019. CrossRef - Antimicrobial Peptides: An Approach to Combat Resilient Infections
Debaprasad Parai, Pia Dey, Samir K. Mukherjee
Current Drug Discovery Technologies.2020; 17(4): 542. CrossRef - Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
C. Verheecke‐Vaessen, J. Monte, E. Garcia‐Cela, N. Magan, A. Medina
Letters in Applied Microbiology.2020; 71(5): 459. CrossRef - Application of Biophysical Techniques to Investigate the Interaction of Antimicrobial Peptides With Bacterial Cells
Maria Luisa Gelmi, Luca Domenico D'Andrea, Alessandra Romanelli
Frontiers in Medical Technology.2020;[Epub] CrossRef - Crotamine and crotalicidin, membrane active peptides from Crotalus durissus terrificus rattlesnake venom, and their structurally-minimized fragments for applications in medicine and biotechnology
Claudio Borges Falcao, Gandhi Radis-Baptista
Peptides.2020; 126: 170234. CrossRef - Protecting the outside: biological tools to manipulate the skin microbiota
Julie N O'Sullivan, Mary C Rea, Colin Hill, R Paul Ross
FEMS Microbiology Ecology.2020;[Epub] CrossRef - Therapeutic potential of a designed CSαβ peptide ID13 in Staphylococcus aureus-induced endometritis of mice
Bing Li, Na Yang, Yuxue Shan, Xiumin Wang, Ya Hao, Ruoyu Mao, Da Teng, Huan Fan, Jianhua Wang
Applied Microbiology and Biotechnology.2020; 104(15): 6693. CrossRef - Ark shell protein‐derived bioactive peptides promote osteoblastic differentiation through upregulation of the canonical Wnt/β‐catenin signaling in human bone marrow‐derived mesenchymal stem cells
Yunok Oh, Chang‐Bum Ahn, Jae‐Young Je
Journal of Food Biochemistry.2020;[Epub] CrossRef - Influence of Different Aromatic Hydrophobic Residues on the Antimicrobial Activity and Membrane Selectivity of BRBR-NH2 Tetrapeptide
Lei Liu, Liling Zhao, Lixia Liu, Shizhong Yue, Jihua Wang, Zanxia Cao
Langmuir.2020; 36(50): 15331. CrossRef - Direct antimicrobial activity of cationic amphipathic peptide WLBU2 against Staphylococcus aureus biofilms is enhanced in physiologic buffered saline
Jonathan B. Mandell, John A. Koch, Berthony Deslouches, Kenneth L. Urish
Journal of Orthopaedic Research.2020; 38(12): 2657. CrossRef - Clinical Applications of Antimicrobial Peptides (AMPs): Where do we Stand Now?
Mithoor Divyashree, Madhu K. Mani, Dhanasekhar Reddy, Ranjith Kumavath, Preetam Ghosh, Vasco Azevedo, Debmalya Barh
Protein & Peptide Letters.2020; 27(2): 120. CrossRef - Microwave‐assisted extraction (MAE) combined with gas chromatography–mass spectrometry (GC–MS) for determination of volatile small molecules to evaluate compatibility of antimicrobial peptide PL‐5 spray with packaging materials
Chu Liu, Xiangyong Yu, Zhaorui Meng, Ning Zhao, Fujuan Bai, Longshan Zhao
Biomedical Chromatography.2020;[Epub] CrossRef - Temporin L-derived peptide as a regulator of the acute inflammatory response in zymosan-induced peritonitis
Rosa Bellavita, Federica Raucci, Francesco Merlino, Marialuisa Piccolo, Maria Grazia Ferraro, Carlo Irace, Rita Santamaria, Asif J. Iqbal, Ettore Novellino, Paolo Grieco, Nicola Mascolo, Francesco Maione
Biomedicine & Pharmacotherapy.2020; 123: 109788. CrossRef - An automatic representation of peptides for effective antimicrobial activity classification
Jesus A. Beltran, Gabriel Del Rio, Carlos A. Brizuela
Computational and Structural Biotechnology Journal.2020; 18: 455. CrossRef - Double-Headed Cationic Lipopeptides: An Emerging Class of Antimicrobials
Izabela Małuch, Oktawian Stachurski, Paulina Kosikowska-Adamus, Marta Makowska, Marta Bauer, Dariusz Wyrzykowski, Aleksandra Hać, Wojciech Kamysz, Milena Deptuła, Michał Pikuła, Emilia Sikorska
International Journal of Molecular Sciences.2020; 21(23): 8944. CrossRef - Antimicrobial Susceptibility Testing of Antimicrobial Peptides to Better Predict Efficacy
Derry K. Mercer, Marcelo D. T. Torres, Searle S. Duay, Emma Lovie, Laura Simpson, Maren von Köckritz-Blickwede, Cesar de la Fuente-Nunez, Deborah A. O'Neil, Alfredo M. Angeles-Boza
Frontiers in Cellular and Infection Microbiology.2020;[Epub] CrossRef - Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential
Nelson G. J. Oliveira, Marlon H. Cardoso, Nadya Velikova, Marcel Giesbers, Jerry M. Wells, Taia M. B. Rezende, Renko de Vries, Octávio L. Franco
Scientific Reports.2020;[Epub] CrossRef - Pseudonajide peptide derived from snake venom alters cell envelope integrity interfering on biofilm formation in Staphylococcus epidermidis
Rafael Schneider, Muriel Primon-Barros, Rafael Gomes Von Borowski, Sophie Chat, Sylvie Nonin-Lecomte, Reynald Gillet, Alexandre José Macedo
BMC Microbiology.2020;[Epub] CrossRef - An Enhanced Variant Designed From DLP4 Cationic Peptide Against Staphylococcus aureus CVCC 546
Bing Li, Na Yang, Xiumin Wang, Ya Hao, Ruoyu Mao, Zhanzhan Li, Zhenlong Wang, Da Teng, Jianhua Wang
Frontiers in Microbiology.2020;[Epub] CrossRef - Strategies for recombinant production of antimicrobial peptides with pharmacological potential
Kamila Botelho Sampaio de Oliveira, Michel Lopes Leite, Gisele Regina Rodrigues, Harry Morales Duque, Rosiane Andrade da Costa, Victor Albuquerque Cunha, Lorena Sousa de Loiola Costa, Nicolau Brito da Cunha, Octavio Luiz Franco, Simoni Campos Dias
Expert Review of Clinical Pharmacology.2020; 13(4): 367. CrossRef - Kinetoplastid Membrane Protein-11 Induces Pores in Anionic Phospholipid Membranes: Effect of Cholesterol
Animesh Halder, Achinta Sannigrahi, Nayan De, Krishnananda Chattopadhyay, Sanat Karmakar
Langmuir.2020; 36(13): 3522. CrossRef - Interactions of “de novo” designed peptides with bacterial membranes: Implications in the antimicrobial activity
Patricia Maturana, Sónia Gonçalves, Melina Martinez, Juan C. Espeche, Nuno C. Santos, Liliana Semorile, Paulo C. Maffia, Axel Hollmann
Biochimica et Biophysica Acta (BBA) - Biomembranes.2020; 1862(11): 183443. CrossRef - Tailoring the Physicochemical Properties of Antimicrobial Peptides onto a Thiazole-Based γ-Peptide Foldamer
Clément Bonnel, Baptiste Legrand, Matthieu Simon, Margaux Clavié, Agnès Masnou, Estelle Jumas-Bilak, Young Kee Kang, Patricia Licznar-Fajardo, Ludovic T. Maillard, Nicolas Masurier
Journal of Medicinal Chemistry.2020; 63(17): 9168. CrossRef - Expression and Roles of Antimicrobial Peptides in Innate Defense of Airway Mucosa: Potential Implication in Cystic Fibrosis
Regina Geitani, Carole Ayoub Moubareck, Zhengzhong Xu, Dolla Karam Sarkis, Lhousseine Touqui
Frontiers in Immunology.2020;[Epub] CrossRef - PACAP Is Lethal to Flavobacterium psychrophilum Through Either Direct Membrane Permeabilization or Indirectly, by Priming the Immune Response in Rainbow Trout Macrophages
Shawna L. Semple, Tania Rodríguez-Ramos, Yamila Carpio, John S. Lumsden, Mario P. Estrada, Brian Dixon
Frontiers in Immunology.2019;[Epub] CrossRef - Self-Association of Antimicrobial Peptides: A Molecular Dynamics Simulation Study on Bombinin
Peicho Petkov, Elena Lilkova, Nevena Ilieva, Leandar Litov
International Journal of Molecular Sciences.2019; 20(21): 5450. CrossRef - A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK
María Verónica Húmpola, María Carolina Rey, Pablo Gabriel Spontón, Arturo Carlos Simonetta, Georgina Guadalupe Tonarelli
Protein & Peptide Letters.2019; 26(3): 192. CrossRef - Perspectives on synthetic pharmacotherapy for the treatment of nosocomial pneumonia
Ana Motos, Hua Yang, Minlan Yang, Antoni Torres
Expert Opinion on Pharmacotherapy.2019; 20(12): 1439. CrossRef - Disulfide engineering on temporin‐SHf: Stabilizing the bioactive conformation of an ultra‐short antimicrobial peptide
Ashwini Dolle, Veera Babu Nagati, Yamanappa Hunashal, Kiran Krishnamurthy, Anil Kumar Pasupulati, Srinivasarao Raghothama, Konkallu Hanumae Gowd
Chemical Biology & Drug Design.2019; 94(3): 1634. CrossRef - Antimicrobial peptides activity in the skin
Anna Herman, Andrzej P. Herman
Skin Research and Technology.2019; 25(2): 111. CrossRef - Structural determinants conferring unusual long life in human serum to rattlesnake‐derived antimicrobial peptide Ctn[15‐34]
Clara Pérez‐Peinado, Susana A. Dias, Diogo A. Mendonça, Miguel A.R.B. Castanho, Ana S. Veiga, David Andreu
Journal of Peptide Science.2019;[Epub] CrossRef - A putative antimicrobial peptide from Hymenoptera in the megaplasmid pSCL4 of Streptomyces clavuligerus ATCC 27064 reveals a singular case of horizontal gene transfer with potential applications
Sebastián Ayala‐Ruano, Daniela Santander‐Gordón, Eduardo Tejera, Yunierkis Perez‐Castillo, Vinicio Armijos-Jaramillo
Ecology and Evolution.2019; 9(5): 2602. CrossRef - A Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities
Miaoran Li, Xinping Xi, Chengbang Ma, Xiaoling Chen, Mei Zhou, James F. Burrows, Tianbao Chen, Lei Wang
Biomolecules.2019; 9(10): 628. CrossRef - Antimicrobial Peptides: Recent Insights on Biotechnological Interventions and Future Perspectives
Rajeshwari Sinha, Pratyoosh Shukla
Protein & Peptide Letters.2019; 26(2): 79. CrossRef - Cationic antimicrobial peptides: alternatives and/or adjuvants to antibiotics active against methicillin-resistant Staphylococcus aureus and multidrug-resistant Pseudomonas aeruginosa
Regina Geitani, Carole Ayoub Moubareck, Lhousseine Touqui, Dolla Karam Sarkis
BMC Microbiology.2019;[Epub] CrossRef - Supramolecular Antibacterial Materials for Combatting Antibiotic Resistance
Xingshu Li, Haotian Bai, Yuchong Yang, Juyoung Yoon, Shu Wang, Xi Zhang
Advanced Materials.2019;[Epub] CrossRef - Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32
Bomai K. Kerenga, James A. McKenna, Peta J. Harvey, Pedro Quimbar, Donovan Garcia-Ceron, Fung T. Lay, Thanh Kha Phan, Prem K. Veneer, Shaily Vasa, Kathy Parisi, Thomas M. A. Shafee, Nicole L. van der Weerden, Mark D. Hulett, David J. Craik, Marilyn A. And
Frontiers in Microbiology.2019;[Epub] CrossRef - Péptidos antimicrobianos, una alternativa prometedora para el tratamiento de enfermedades infecciosas
Kevin Samael Olascoaga-Del Angel, Grecia Sánchez-Evangelista, Israel Carmona-Navarrete, María del Carmen Galicia-Sanchez, Angélica Gómez-Luna, Susan Janneth Islas-Arollo, Jorge Ismael Castañeda-Sánchez
Kompass Neumología.2019; 1(1): 15. CrossRef - Susceptibility of microbial cells to the modified PIP2-binding sequence of gelsolin anchored on the surface of magnetic nanoparticles
Robert Bucki, Katarzyna Niemirowicz-Laskowska, Piotr Deptuła, Agnieszka Z. Wilczewska, Paweł Misiak, Bonita Durnaś, Krzysztof Fiedoruk, Ewelina Piktel, Joanna Mystkowska, Paul A. Janmey
Journal of Nanobiotechnology.2019;[Epub] CrossRef - Positive Charge Patterning and Hydrophobicity of Membrane-Active Antimicrobial Peptides as Determinants of Activity, Toxicity, and Pharmacokinetic Stability
Tracy A. Stone, Gregory B. Cole, Dorna Ravamehr-Lake, Huong Q. Nguyen, Farheen Khan, Simon Sharpe, Charles M. Deber
Journal of Medicinal Chemistry.2019; 62(13): 6276. CrossRef - Designer Peptide and Protein Dendrimers: A Cross-Sectional Analysis
Rachit Sapra, Ram P. Verma, Govind P. Maurya, Sameer Dhawan, Jisha Babu, V. Haridas
Chemical Reviews.2019; 119(21): 11391. CrossRef - A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes
Maria Grazia Cusimano, Angelo Spinello, Giampaolo Barone, Domenico Schillaci, Stella Cascioferro, Alessandra Magistrato, Barbara Parrino, Vincenzo Arizza, Maria Vitale
Marine Drugs.2019; 17(3): 159. CrossRef - Systematical Analysis of the Protein Targets of Lactoferricin B and Histatin-5 Using Yeast Proteome Microarrays
Pramod Shah, Wei-Sheng Wu, Chien-Sheng Chen
International Journal of Molecular Sciences.2019; 20(17): 4218. CrossRef - Antiseptic Effect of Ps-K18: Mechanism of Its Antibacterial and Anti-Inflammatory Activities
Mihee Jang, Jieun Kim, Yujin Choi, JeongKyu Bang, Yangmee Kim
International Journal of Molecular Sciences.2019; 20(19): 4895. CrossRef - Pullulan nanofibers containing the antimicrobial palindromic peptide LfcinB (21–25)Palobtainedviaelectrospinning
Julieth Tatiana Román, Carlos Alberto Fuenmayor, Carlos Mario Zuluaga Dominguez, Dianney Clavijo-Grimaldo, Martha Acosta, Javier Eduardo García-Castañeda, Ricardo Fierro-Medina, Zuly Jenny Rivera-Monroy
RSC Advances.2019; 9(35): 20432. CrossRef - Replacement of l-Amino Acids by d-Amino Acids in the Antimicrobial Peptide Ranalexin and Its Consequences for Antimicrobial Activity and Biodistribution
Cornelius Domhan, Philipp Uhl, Christian Kleist, Stefan Zimmermann, Florian Umstätter, Karin Leotta, Walter Mier, Michael Wink
Molecules.2019; 24(16): 2987. CrossRef - A New Hope: Self-Assembling Peptides with Antimicrobial Activity
Lucia Lombardi, Annarita Falanga, Valentina Del Genio, Stefania Galdiero
Pharmaceutics.2019; 11(4): 166. CrossRef - Effects of the antimicrobial peptide L12 against multidrug‑resistant Staphylococcus aureus
Fu Xiong, Xiaotian Dai, Yu‑Xue Li, Rui Wei, Li An, Yajuan Wang, Zhenhong Chen
Molecular Medicine Reports.2019;[Epub] CrossRef - Utilization of antimicrobial peptides, analogues and mimics in creating antimicrobial surfaces and bio-materials
Ingrid Batista Pinto, Leandro dos Santos Machado, Beatriz Torres Meneguetti, Micaella Lima Nogueira, Cristiano Marcelo Espínola Carvalho, Antonia Railda Roel, Octávio Luiz Franco
Biochemical Engineering Journal.2019; 150: 107237. CrossRef - Drug delivery systems designed to overcome antimicrobial resistance
Thanh‐Nhat Pham, Pauline Loupias, Alexandra Dassonville‐Klimpt, Pascal Sonnet
Medicinal Research Reviews.2019; 39(6): 2343. CrossRef - Discovery of a Novel Antimicrobial Lipopeptide, Brevibacillin V, from Brevibacillus laterosporus fmb70 and Its Application on the Preservation of Skim Milk
Yubo Wu, Libang Zhou, Fengxia Lu, Xiaomei Bie, Haizhen Zhao, Chong Zhang, Zhaoxin Lu, Yingjian Lu
Journal of Agricultural and Food Chemistry.2019; 67(45): 12452. CrossRef - Biotechnological Production of the Cell Penetrating Antifungal PAF102 Peptide in Pichia pastoris
Crina Popa, Xiaoqing Shi, Tarik Ruiz, Pau Ferrer, María Coca
Frontiers in Microbiology.2019;[Epub] CrossRef - Hepcidin gene of Indian major carp, Labeo rohita: Molecular, structural and functional characterization, and antibacterial activity of recombinant hepcidin
Amruta Mohapatra, A. Dixit, L.C. Garg, P.K. Sahoo
Aquaculture.2019; 511: 734218. CrossRef - Profiling antimicrobial peptides from the medical maggotLucilia sericataas potential antibiotics for MDR Gram-negative bacteria
Rolf Hirsch, Jochen Wiesner, Alexander Marker, Yvonne Pfeifer, Armin Bauer, Peter E Hammann, Andreas Vilcinskas
Journal of Antimicrobial Chemotherapy.2019; 74(1): 96. CrossRef - Profiling of Polar Metabolites in Mouse Feces Using Four Analytical Platforms to Study the Effects Of Cathelicidin-Related Antimicrobial Peptide in Alcoholic Liver Disease
Liqing He, Fengyuan Li, Xinmin Yin, Patrick Bohman, Seongho Kim, Craig J. McClain, Wenke Feng, Xiang Zhang
Journal of Proteome Research.2019; 18(7): 2875. CrossRef - Antifungal Activity, Toxicity, and Membranolytic Action of a Mastoparan Analog Peptide
Junya de Lacorte Singulani, Mariana Cristina Galeane, Marina Dorisse Ramos, Paulo César Gomes, Claudia Tavares dos Santos, Bibiana Monson de Souza, Mario Sergio Palma, Ana Marisa Fusco Almeida, Maria José Soares Mendes Giannini
Frontiers in Cellular and Infection Microbiology.2019;[Epub] CrossRef - Tryptophan-Rich and Proline-Rich Antimicrobial Peptides
Awdhesh Mishra, Jaehyuk Choi, Eunpyo Moon, Kwang-Hyun Baek
Molecules.2018; 23(4): 815. CrossRef - The Effect of Polymer Microstructure on Encapsulation Efficiency and Release Kinetics of Citropin 1.1 from the Poly(ε-caprolactone) Microparticles
Urszula Piotrowska, Ewa Oledzka, Wojciech Kamysz, Sławomir Białek, Marcin Sobczak
Nanomaterials.2018; 8(7): 482. CrossRef - Über bisherige Denkweisen hinaus – neue Wirkstoffe zur Überwindung der Antibiotika‐Krise
Markus Lakemeyer, Weining Zhao, Franziska A. Mandl, Peter Hammann, Stephan A. Sieber
Angewandte Chemie.2018; 130(44): 14642. CrossRef - Antitumor activity of RT2 peptide derived from crocodile leukocyte peptide on human colon cancer xenografts in nude mice
Pornsuda Maraming, Sompong Klaynongsruang, Patcharee Boonsiri, Surachai Maijaroen, Sakda Daduang, Jing‐Gung Chung, Jureerut Daduang
Environmental Toxicology.2018; 33(9): 972. CrossRef - Immunological Tolerance, Pregnancy, and Preeclampsia: The Roles of Semen Microbes and the Father†
Louise C. Kenny, Douglas B. Kell
Frontiers in Medicine.2018;[Epub] CrossRef - A Recombinant Snake Cathelicidin Derivative Peptide: Antibiofilm Properties and Expression in Escherichia coli
Mercedeh Tajbakhsh, Maziar Mohammad Akhavan, Fatemeh Fallah, Abdollah Karimi
Biomolecules.2018; 8(4): 118. CrossRef - Regulated Cell Death as a Therapeutic Target for Novel Antifungal Peptides and Biologics
Michael R. Yeaman, Sabrina Büttner, Karin Thevissen, Alessandra Ricelli
Oxidative Medicine and Cellular Longevity.2018;[Epub] CrossRef - Antimicrobial peptides of buffalo and their role in host defenses
Khangembam Victoria Chanu, Dimpal Thakuria, Satish Kumar
Veterinary World.2018; 11(2): 192. CrossRef - The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF
Christoph Sonderegger, Györgyi Váradi, László Galgóczy, Sándor Kocsubé, Wilfried Posch, Attila Borics, Sandrine Dubrac, Gábor K. Tóth, Doris Wilflingseder, Florentine Marx
Frontiers in Microbiology.2018;[Epub] CrossRef - Antimicrobial activities of a proline-rich proprotein from Spodoptera litura
Li-Ling Yang, Ming-Yue Zhan, Yu-Li Zhuo, Yue-Min Pan, Yang Xu, Xiu-Hong Zhou, Pei-Jin Yang, Hong-Li Liu, Zi-Hao Liang, Xiao-Dan Huang, Xiao-Qiang Yu, Xiang-Jun Rao
Developmental & Comparative Immunology.2018; 87: 137. CrossRef - Cell-Selective Pore Forming Antimicrobial Peptides of the Prodomain of Human Furin: A Conserved Aromatic/Cationic Sequence Mapping, Membrane Disruption, and Atomic-Resolution Structure and Dynamics
Sheetal Sinha, Munesh Kumar Harioudh, Rikeshwer P. Dewangan, Wun Jern Ng, Jimut Kanti Ghosh, Surajit Bhattacharjya
ACS Omega.2018; 3(11): 14650. CrossRef - Thinking Outside the Box—Novel Antibacterials To Tackle the Resistance Crisis
Markus Lakemeyer, Weining Zhao, Franziska A. Mandl, Peter Hammann, Stephan A. Sieber
Angewandte Chemie International Edition.2018; 57(44): 14440. CrossRef - Breaking the frontiers of cosmetology with antimicrobial peptides
Thuany Alencar-Silva, Mariana Carolina Braga, Gustavo Oliveira Silva Santana, Felipe Saldanha-Araujo, Robert Pogue, Simoni Campos Dias, Octavio Luiz Franco, Juliana Lott Carvalho
Biotechnology Advances.2018; 36(8): 2019. CrossRef - From Antimicrobial Peptides to Antimicrobial Poly(α‐amino acid)s
Wei Shen, Pan He, Chunsheng Xiao, Xuesi Chen
Advanced Healthcare Materials.2018;[Epub] CrossRef - Designing improved active peptides for therapeutic approaches against infectious diseases
Bárbara Gomes, Marcelo T. Augusto, Mário R. Felício, Axel Hollmann, Octávio L. Franco, Sónia Gonçalves, Nuno C. Santos
Biotechnology Advances.2018; 36(2): 415. CrossRef - Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds
Anja Pfalzgraff, Klaus Brandenburg, Günther Weindl
Frontiers in Pharmacology.2018;[Epub] CrossRef - Antimicrobial Peptides and Nanotechnology, Recent Advances and Challenges
Lubhandwa S. Biswaro, Mauricio G. da Costa Sousa, Taia M. B. Rezende, Simoni C. Dias, Octavio L. Franco
Frontiers in Microbiology.2018;[Epub] CrossRef - Bioinspired Designs, Molecular Premise and Tools for Evaluating the Ecological Importance of Antimicrobial Peptides
Elvis Legala Ongey, Stephan Pflugmacher, Peter Neubauer
Pharmaceuticals.2018; 11(3): 68. CrossRef - Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries
Ana Gomes, Cátia Teixeira, Ricardo Ferraz, Cristina Prudêncio, Paula Gomes
Molecules.2017; 22(10): 1743. CrossRef - Potential role of an antimicrobial peptide, KLK in inhibiting lipopolysaccharide-induced macrophage inflammation
Pornpimon Jantaruk, Sittiruk Roytrakul, Sutthirat Sitthisak, Duangkamol Kunthalert, Anirban Bhunia
PLOS ONE.2017; 12(8): e0183852. CrossRef - Design, Recombinant Fusion Expression and Biological Evaluation of Vasoactive Intestinal Peptide Analogue as Novel Antimicrobial Agent
Chunlan Xu, Yu Guo, Xiangjin Qiao, Xiaoya Shang, Weining Niu, Mingliang Jin
Molecules.2017; 22(11): 1963. CrossRef - Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
Sónia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval, Aurélie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan, Yen-Hua Huang, David J. Craik
ACS Chemical Biology.2017; 12(9): 2324. CrossRef - Peptides with Dual Antimicrobial and Anticancer Activities
Mário R. Felício, Osmar N. Silva, Sônia Gonçalves, Nuno C. Santos, Octávio L. Franco
Frontiers in Chemistry.2017;[Epub] CrossRef - Novel antimicrobial peptide CPF‐C1 analogs with superior stabilities and activities against multidrug‐resistant bacteria
Junqiu Xie, Qian Zhao, Sisi Li, Zhibin Yan, Jing Li, Yao Li, Lingyun Mou, Bangzhi Zhang, Wenle Yang, Xiaokang Miao, Xianxing Jiang, Rui Wang
Chemical Biology & Drug Design.2017; 90(5): 690. CrossRef - Antimicrobial peptide repertoire of Thitarodes armoricanus, a host species of Ophiocordyceps sinensis, predicted based on de novo transcriptome sequencing and analysis
Min Wang, Xianda Hu
Infection, Genetics and Evolution.2017; 54: 238. CrossRef - Testing cathelicidin susceptibility of bacterial mastitis isolates: Technical challenges and data output for clinical isolates
Melissa N. Langer, Stefanie Blodkamp, Martin Bayerbach, Andrea T. Feßler, Nicole de Buhr, Thomas Gutsmann, Lothar Kreienbrock, Stefan Schwarz, Maren von Köckritz-Blickwede
Veterinary Microbiology.2017; 210: 107. CrossRef - Protein-only, antimicrobial peptide-containing recombinant nanoparticles with inherent built-in antibacterial activity
Naroa Serna, Laura Sánchez-García, Alejandro Sánchez-Chardi, Ugutz Unzueta, Mónica Roldán, Ramón Mangues, Esther Vázquez, Antonio Villaverde
Acta Biomaterialia.2017; 60: 256. CrossRef
- Boc‐Protected Phenylalanine and Tryptophan‐Based Dipeptides: A Broad Spectrum Anti‐Bacterial Agent
Journal Article
- Potential for colonization of O111:H25 atypical enteropathogenic E. coli
- Marta O. Domingos , Keyde C.M. Melo , Irys Viana Neves , Cristiane M. Mota , Rita C. Ruiz , Bruna S. Melo , Raphael C. Lima , Denise S.P.Q. Horton , Monamaris M. Borges , Marcia R. Franzolin
- J. Microbiol. 2016;54(11):745-752. Published online October 29, 2016
- DOI: https://doi.org/10.1007/s12275-016-6015-x
- 71 View
- 0 Download
- 5 Crossref
-
Abstract
- Using clonal phylogenetic methods, it has been demonstrated that O111:H25 atypical enteropathogenic E. coli (aEPEC) strains belong to distinct clones, suggesting the possibility that their ability to interact with different hosts and abiotic surfaces can vary from one clone to another. Accordingly, the ability of O111:H25 aEPEC strains derived from human, cat and dogs to adhere to epithelial cells has been investigated, along with their ability to interact with macrophages and to form biofilms on polystyrene, a polymer used to make biomedical devices. The results demonstrated that all the strains analyzed were able to adhere to, and to form pedestals on, epithelial cells, mechanisms used by E. coli to become strongly attached to the host. The strains also show a Localized-Adherence- Like (LAL) pattern of adhesion on HEp-2 cells, a behavior associated with acute infantile diarrhea. In addition, the O111:H25 aEPEC strains derived either from human or domestic animals were able to form long filaments, a phenomenon used by some bacteria to avoid phagocytosis. O111:H25 aEPEC strains were also encountered inside vacuoles, a characteristic described for several bacterial strains as a way of protecting themselves against the environment. They were also able to induce TNF-α release via two routes, one dependent on TLR-4 and the other dependent on binding of Type I fimbriae. These O111:H25 strains were also able to form biofilms on polystyrene. In summary the results suggest that, regardless of their source (i.e. linked to human origin or otherwise), O111:H25 aEPEC strains carry the potential to cause human disease.
-
Citations
Citations to this article as recorded by- Differences of Escherichia coli isolated from different organs of the individual sheep: molecular typing, antibiotics resistance, and biofilm formation
Zihao Wu, Haoming Chi, Tingting Han, Guangxi Li, Jixue Wang, Wei Chen
Folia Microbiologica.2024; 69(3): 567. CrossRef - Hidden carbapenem resistance in the community- and hospital-associated OXA-48 gene-carrying uropathogenic Escherichia coli
Maryam Talebi, Shahin Najar-Peerayeh, Bita Bakhshi
Gene Reports.2020; 21: 100897. CrossRef - Genetic relation and virulence factors of carbapenemase-producing Uropathogenic Escherichia coli from urinary tract infections in Iraq
Amal Talib Al-Sa'ady, Ghaidaa Jihadi Mohammad, Bashdar Mahmud Hussen
Gene Reports.2020; 21: 100911. CrossRef - Host characteristics and virulence typing of Escherichia coli isolated from diabetic patients
Najar Peerayeh Shahin, Eslami Majid, Talebi Bezmin Abadi Amin, Bakhshi Bita
Gene Reports.2019; 15: 100371. CrossRef - Characterization of uropathogenic E. coli O25b‐B2‐ST131, O15:K52:H1, and CGA: Neutrophils apoptosis, serum bactericidal assay, biofilm formation, and virulence typing
Seyyed Khalil Shokouhi Mostafavi, Shahin Najar‐Peerayeh, Ashraf Mohabbati Mobarez, Mehdi Kardoust Parizi
Journal of Cellular Physiology.2019; 234(10): 18272. CrossRef
- Differences of Escherichia coli isolated from different organs of the individual sheep: molecular typing, antibiotics resistance, and biofilm formation
First
Prev
TOP
