Journal of Microbiology

Full articles

Preliminary characterization of the skin microbiota in basal cell carcinoma: An exploratory pilot study in Korean patients: Hye Lim Keum, Woo Jun Sul, Suyeon Kim, In-Young Chung, Ara Koh, Hei Sung Kim; J. Microbiol. 2026;64(2):e2511012. Published online February 13, 2026; DOI: https://doi.org/10.71150/jm.2511012

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Abstract PDF: Basal cell carcinoma (BCC) is the most common form of skin cancer, with ultraviolet radiation recognized as the primary environmental driver; however, the potential contribution of alterations in the skin microbiota remains incompletely understood, particularly in Asian populations. This exploratory pilot study describes bacterial community patterns in BCC lesions compared with contralateral clinically normal skin in 20 Korean patients. Lesional and contralateral samples were obtained using paired skin swabs and punch biopsies and analyzed by full-length 16S rRNA gene sequencing, with targeted quantitative PCR (qPCR) of the roxP antioxidant gene of Cutibacterium acnes. Given the low-biomass nature of skin samples and the exploratory design, analyses focused on descriptive trends rather than confirmatory inference. Across available samples, C. acnes was the dominant taxon, with a trend toward lower relative abundance in BCC lesions, particularly in biopsy-derived datasets. Microbial evenness appeared higher in lesions than controls. Predictive functional profiling suggested reduced representation of vitamin B6 metabolism pathways in lesions, while qPCR analysis of swab samples showed a trend toward lower roxP/16S rRNA ratios in BCC-associated microbiota. These findings should be interpreted cautiously in light of methodological constraints, including sample heterogeneity, lidocaine exposure prior to biopsy, absence of sequencing-based negative controls, and reliance on predictive functional inference. Overall, this pilot study highlights potential differences in skin bacterial community structure between BCC lesions and contralateral skin in a Korean cohort. Larger, methodologically optimized studies incorporating metagenomic and functional validation will be required to determine whether these microbiota shifts contribute to, or result from, BCC-associated changes in the cutaneous environment.

Ecological characteristics of the truncal skin mycobiome in acne and its association with doxycycline exposure: Hyun Ji Lee, Yong-Joon Cho, Nayan Jin, Piyapat Rintarhat, Won Hee Jung, Hei Sung Kim; J. Microbiol. 2026;64(1):e2511019. Published online January 31, 2026; DOI: https://doi.org/10.71150/jm.2511019

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Abstract PDF Supplementary Material: Truncal acne significantly impairs quality of life yet remains underexplored relative to facial acne, particularly with respect to fungal ecology. The trunk represents a distinct cutaneous niche characterized by thicker epidermis, larger follicular units, and frequent occlusion, and harbors a high abundance of Malassezia species. In this study, we used internal transcribed spacer 2 (ITS2) amplicon sequencing to characterize the truncal mycobiome in patients with acne and in healthy controls and to compare fungal community features across doxycycline exposure groups. Although serial sampling was planned, seven participants contributed a single follow-up sample after doxycycline treatment, and only two participants contributed multiple follow-up samples sufficient for true within-subject longitudinal analyses; therefore, most analyses represent exposure-stratified cross-sectional comparisons rather than confirmed temporal change. At baseline, truncal acne lesions exhibited increased fungal richness and distinct community composition compared with controls. Acne lesions were more frequently enriched for Malassezia globosa, whereas healthy controls were dominated by M. sympodialis. Across doxycycline exposure groups, fungal communities remained Malassezia-dominant with substantial inter-individual variability. Doxycycline exposure was associated with partial and heterogeneous differences in Malassezia species composition without uniform normalization toward control profiles. Because only fungal sequencing was performed, bacterial–fungal interactions were inferred from prior literature and not directly measured. These findings indicate that truncal acne is associated with a distinct fungal community structure and highlight the need for integrated, longitudinal multi-omics studies to clarify treatment-associated microbial dynamics.

Review

Obesity, skin disorders, and the microbiota: Unraveling a complex web: Yu Ri Woo, Hei Sung Kim; J. Microbiol. 2026;64(1):e2508007. Published online January 31, 2026; DOI: https://doi.org/10.71150/jm.2508007

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Abstract PDF: Obesity is increasingly recognized as a systemic pro-inflammatory condition that influences not only metabolic and cardiovascular health but also the development and exacerbation of cutaneous inflammatory diseases. This review examines the interplay between obesity, microbial dysbiosis, and two archetypal inflammatory skin disorders—hidradenitis suppurativa (HS) and psoriasis. We highlight how obesity-induced changes in immune signaling, gut permeability, and microbiota composition—both in the gut and the skin—contribute to cutaneous inflammation. Special emphasis is placed on shared pathways such as the Th17/IL-23 and IL-22 signaling axes, adipokine imbalance, and microbial metabolites like short-chain fatty acids and lipopolysaccharides. The review critically evaluates the current literature, distinguishing preclinical insights from clinical evidence, and underscores the potential of microbiota-targeted therapies and metabolic interventions as adjunctive treatment strategies. By integrating metabolic, immunologic, and microbiome data, we synthesize emerging evidence to better understand the gut–skin–obesity interplay and guide future therapeutic innovations.

Full article

Lactobacillus crispatus KBL693 alleviates atopic dermatitis symptoms through immune modulation: Seokcheon Song, Jun-Hyeong Kim, Sung Jae Jang, Eun Jung Jo, Sang Kyun Lim, GwangPyo Ko; J. Microbiol. 2025;63(10):e2509005. Published online October 31, 2025; DOI: https://doi.org/10.71150/jm.2509005

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Abstract PDF Supplementary Material: Atopic dermatitis (AD) is a widespread inflammatory skin condition that affects the population worldwide. Given the implication of microbiota in AD pathogenesis, we investigated whether human-derived Lactobacillus strains could modulate AD. In this study, we identified Lactobacillus crispatus KBL693 as a probiotic candidate for AD treatment. In vitro, KBL693 suppressed mast cell degranulation and IL-4 production by T cells, suggesting its ability to attenuate key type 2 immune responses. Consistent outcomes were observed in a murine AD model, where oral administration of KBL693 alleviated disease symptoms and reduced hallmark type 2 immune markers, including plasma IgE as well as IL-4, IL-5, and IL-13 levels in skin lesions. In addition to downregulating these AD-associated immune responses, KBL693 promoted regulatory T cell (Treg) expansion in mesenteric lymph nodes, indicating its potential to restore immune balance. Collectively, these findings highlight the therapeutic potential of KBL693 for AD through enhancement of Tregs and suppression of type 2 immune responses.

Research Article

Characteristics of skin microbiome associated with disease severity in systemic sclerosis: Kyung-Ann Lee, Asad Ul-Haq, Hoonhee Seo, Sujin Jo, Sukyung Kim, Ho-Yeon Song, Hyun-Sook Kim; J. Microbiol. 2025;63(1):e.2409018. Published online January 24, 2025; DOI: https://doi.org/10.71150/jm.2409018

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Abstract PDF Supplementary Material

Systemic sclerosis (SSc) is a chronic autoimmune disorder characterised by skin fibrosis and internal organ involvement. Disruptions in the microbial communities on the skin may contribute to the onset of autoimmune diseases that affect the skin. However, current research on the skin microbiome in SSc is lacking. This study aimed to investigate skin microbiome associated with disease severity in SSc. Skin swabs were collected from the upper limbs of 46 healthy controls (HCs) and 36 patients with SSc. Metagenomic analysis based on the 16S rRNA gene was conducted and stratified by cutaneous subtype and modified Rodnan skin score (mRSS) severity. Significant differences in skin bacterial communities were observed between the HCs and patients with SSc, with further significant variations based on subtype and mRSS severity. The identified biomarkers were Bacteroides and Faecalibacterium for patients with diffuse cutaneous SSc with high mRSS (≥ 10) and Mycobacterium and Parabacteroides for those with low mRSS (< 10). Gardnerella, Abies, Lactobacillus, and Roseburia were the biomarkers in patients with limited cutaneous SSc (lcSS) and high mRSS, whereas Coprococcus predominated in patients with lcSS and low mRSS. Cutaneous subtype analysis identified Pediococcus as a biomarker in the HCs, whereas mRSS analysis revealed the presence of Pseudomonas in conjunction with Pediococcus. In conclusion, patients with SSc exhibit distinct skin microbiota compared with healthy controls. Bacterial composition varies by systemic sclerosis cutaneous subtype and skin thickness.

Citations

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Review

Skin Deep: The Potential of Microbiome Cosmetics: Ju Hee Han, Hei Sung Kim; J. Microbiol. 2024;62(3):181-199. Published online April 16, 2024; DOI: https://doi.org/10.1007/s12275-024-00128-x

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Abstract PDF

The interplay between the skin microbiome and its host is a complex facet of dermatological health and has become a critical focus in the development of microbiome cosmetics. The skin microbiome, comprising various microorganisms, is essential from birth, develops over the lifespan, and performs vital roles in protecting our body against pathogens, training the immune system, and facilitating the breakdown of organic matter. Dysbiosis, an imbalance of these microorganisms, has been implicated in a number of skin conditions such as acne, atopic dermatitis, and skin cancer. Recent scientific findings have spurred cosmetic companies to develop products that preserve and enhance the skin's microbial diversity balance. These products may incorporate elements like prebiotics, probiotics, and postbiotics, which are beneficial for the skin microbiome. Beyond topical products, there's increasing interest in ingestible beauty supplements (i.e. oral probiotics), highlighting the connection between the gut and skin. This review examines the influence of the microbiome on skin health and the emerging trends of microbiome skincare products.

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From Dysbiosis to Inflammation: Gut Microbiota and Oxidative Stress in Atopic Dermatitis
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Influence of Cosmetic Skincare Products with pH < 5 on the Skin Microbiome: A Randomized Clinical Evaluation
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Journal Article

Thioredoxin A of Streptococcus suis Serotype 2 Contributes to Virulence by Inhibiting the Expression of Pentraxin 3 to Promote Survival Within Macrophages: Chijun Zhao , Xinglin Jia , Yanying Pan , Simeng Liao , Shuo Zhang , Chunxiao Ji , Guangwei Kuang , Xin Wu , Quan Liu , Yulong Tang , Lihua Fang; J. Microbiol. 2023;61(4):433-448. Published online April 3, 2023; DOI: https://doi.org/10.1007/s12275-023-00038-4

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Abstract PDF

Streptococcus suis serotype 2 (SS2) is an important zoonotic pathogen that can infect humans in contact with infected pigs or their byproducts. It can employ different types of genes to defend against oxidative stress and ensure its survival. The thioredoxin (Trx) system is a key antioxidant system that contributes adversity adaptation and pathogenicity. SS2 has been shown to encode putative thioredoxin genes, but the biological roles, coding sequence, and underlying mechanisms remains uncharacterized. Here, we demonstrated that SSU05_0237-ORF, from a clinical SS2 strain, ZJ081101, encodes a protein of 104 amino acids with a canonical CGPC active motif and an identity 70–85% similar to the thioredoxin A (TrxA) in other microorganisms. Recombinant TrxA efficiently catalyzed the thiol-disulfide oxidoreduction of insulin. The deletion of TrxA led to a significantly slow growth and markedly compromised tolerance of the pathogen to temperature stress, as well as impaired adhesion ability to pig intestinal epithelial cells (IPEC-J2). However, it was not involved in H2O2 and paraquat-induced oxidative stress. Compared with the wild-type strain, the ΔTrxA strain was more susceptible to killing by macrophages through increasing NO production. Treatment with TrxA mutant strain also significantly attenuated cytotoxic effects on RAW 264.7 cells by inhibiting inflammatory response and apoptosis. Knockdown of pentraxin 3 in RAW 264.7 cells was more vulnerable to phagocytic activity, and TrxA promoted SS2 survival in phagocytic cells depending on pentraxin 3 activity compared with the wild-type strain. Moreover, a co-inoculation experiment in mice revealed that TrxA mutant strain is far more easily cleared from the body than the wild type strain in the period from 8–24 h, and exhibits significantly attenuated oxidative stress and liver injury. In summary, we reveal the important role of TrxA in the pathogenesis of SS2.

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Decadal advances and future prospects in subunit vaccine development against Streptococcus suis infection
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Review

Nanoparticle and virus-like particle vaccine approaches against SARS-CoV-2: Chulwoo Kim , Jae-Deog Kim , Sang-Uk Seo; J. Microbiol. 2022;60(3):335-346. Published online January 28, 2022; DOI: https://doi.org/10.1007/s12275-022-1608-z

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Abstract PDF

The global spread of coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has provoked an urgent need for prophylactic measures. Several innovative vaccine platforms have been introduced and billions of vaccine doses have been administered worldwide. To enable the creation of safer and more effective vaccines, additional platforms are under development. These include the use of nanoparticle (NP) and virus-like particle (VLP) technology. NP vaccines utilize self-assembling scaffold structures designed to load the entire spike protein or receptor-binding domain of SARS-CoV-2 in a trimeric configuration. In contrast, VLP vaccines are genetically modified recombinant viruses that are considered safe, as they are generally replication-defective. Furthermore, VLPs have indigenous immunogenic potential due to their microbial origin. Importantly, NP and VLP vaccines have shown stronger immunogenicity with greater protection by mimicking the physicochemical characteristics of SARS-CoV-2. The study of NPand VLP-based coronavirus vaccines will help ensure the development of rapid-response technology against SARS-CoV-2 variants and future coronavirus pandemics.

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Two years of COVID-19 pandemic: where are we now?
Jinjong Myoung
Journal of Microbiology.2022; 60(3): 235. CrossRef
Immunogenicity and protective potential of chimeric virus-like particles containing SARS-CoV-2 spike and H5N1 matrix 1 proteins
Jing Chen, Wang Xu, Letian Li, Lichao Yi, Yuhang Jiang, Pengfei Hao, Zhiqiang Xu, Wancheng Zou, Peiheng Li, Zihan Gao, Mingyao Tian, Ningyi Jin, Linzhu Ren, Chang Li
Frontiers in Cellular and Infection Microbiology.2022;[Epub] CrossRef
Construction, Characterization, and Application of a Nonpathogenic Virus-like Model for SARS-CoV-2 Nucleocapsid Protein by Phage Display
Yuting Wu, Bing Liu, Zhiwei Liu, Pengjie Zhang, Xihui Mu, Zhaoyang Tong
Toxins.2022; 14(10): 683. CrossRef
Contribution of T- and B-cell intrinsic toll-like receptors to the adaptive immune response in viral infectious diseases
Ejuan Zhang, Zhiyong Ma, Mengji Lu
Cellular and Molecular Life Sciences.2022;[Epub] CrossRef

Journal Articles

Description of Microbacterium luteum sp. nov., Microbacterium cremeum sp. nov., and Microbacterium atlanticum sp. nov., three novel C50 carotenoid producing bacteria: Fuquan Xie , Siwen Niu , Xihuang Lin , Shengxiang Pei , Li Jiang , Yun Tian , Gaiyun Zhang; J. Microbiol. 2021;59(10):886-897. Published online September 7, 2021; DOI: https://doi.org/10.1007/s12275-021-1186-5

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Abstract PDF

We have identified three Microbacterium strains, A18JL200T, NY27T, and WY121T, that produce C50 carotenoids. Taxonomy shows they represent three novel species. These strains shared < 98.5% 16S rRNA gene sequence identity with each other and were closely related to Microbacterium aquimaris JCM 15625T, Microbacterium yannicii JCM 18959T, Microbacterium ureisolvens CFH S00084T, and Microbacterium hibisci CCTCC AB 2016180T. Digital DNA-DNA hybridization (dDDH) values and average nucleotide identity (ANI) showed differences among the three strains and from their closest relatives, with values ranging from 20.4% to 34.6% and 75.5% to 87.6%, respectively. These values are below the threshold for species discrimination. Both morphology and physiology also differed from those of phylogenetically related Microbacterium species, supporting that they are indeed novel species. These strains produce C50 carotenoids (mainly decaprenoxanthin). Among the three novel species, A18JL200T had the highest total yield in carotenoids (6.1 mg/L or 1.2 mg/g dry cell weight). Unusual dual isoprenoid biosynthetic pathways (methylerythritol phosphate and mevalonate pathways) were annotated for strain A18JL200T. In summary, we found strains of the genus Microbacterium that are potential producers of C50 carotenoids, but their genome has to be investigated further.

Citations

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Identification, evaluation, control of yellow-causing bacteria and their influence on the quality of high moisture rice-based food
Sijie Zhang, Lin Ou, Cuiping Yi, Qiutao Xie, Yang Shan
Food Control.2025; 168: 110887. CrossRef
Microbacterium xanthum sp. nov. Isolated from Seaweed, with the Reclassification of Microbacterium ihumii Yacouba et al. 2023 as a Later Heterotypic Synonym of Microbacterium tenebrionis Lee and Kim 2023
Soon Dong Lee, Hong Lim Yang, In Seop Kim
Current Microbiology.2025;[Epub] CrossRef
Description of Microbacterium luticellae sp. nov., Microbacterium alcoholitolerans sp. nov. and Microbacterium daqui sp. nov. isolated from baijiu pit mud and daqu
Mingkai Tian, Ye Lu, Xinyu Liu, Yi Yan, Jialiang Xu
International Journal of Systematic and Evolutionary Microbiology .2025;[Epub] CrossRef
Chlamydomonas reinhardtii and Microbacterium forte sp. nov., a mutualistic association that favors sustainable hydrogen production
Neda Fakhimi, María Jesus Torres, Emilio Fernández, Aurora Galván, Alexandra Dubini, David González-Ballester
Science of The Total Environment.2024; 913: 169559. CrossRef
Discovery of a new bacterium, Microbacterium betulae sp. nov., in birch wood associated with hypersensitivity pneumonitis in woodworkers
Mariola Paściak, Krzysztof J. Pawlik, Dariusz Martynowski, Łukasz Łaczmański, Jarosław Ciekot, Bogumiła Szponar, Angelina Wójcik‐Fatla, Barbara Mackiewicz, Ewelina Farian, Grażyna Cholewa, Alicja Cholewa, Jacek Dutkiewicz
Environmental Microbiology Reports.2024;[Epub] CrossRef
Microbacterium aquilitoris sp. nov. and Microbacterium gwkjiense sp. nov., isolated from beach
Soon Dong Lee, Hong Lim Yang, Ji-Sun Kim, In Seop Kim
Archives of Microbiology.2024;[Epub] CrossRef
Microbacterium algihabitans sp. nov., Microbacterium phycohabitans sp. nov., and Microbacterium galbum sp. nov., isolated from dried beach seaweeds
Soon Dong Lee, Hong Lim Yang, In Seop Kim
International Journal of Systematic and Evolutionary Microbiology .2024;[Epub] CrossRef
Association between the gut microbiome and carotenoid plumage phenotype in an avian hybrid zone
Marcella D. Baiz, Andrew W. Wood, David P. L. Toews
Proceedings of the Royal Society B: Biological Sciences.2024;[Epub] CrossRef
Description of Microbacterium dauci sp. nov., a plant growth hormone indoleacetic acid-producing and nitrogen-fixing bacterium isolated from carrot rhizosphere soil
Jiawen Zheng, Yunyu Liao, Yang Li, Dongsheng Li, Yaping Sun, Zijun Xiao
Archives of Microbiology.2024;[Epub] CrossRef
Can Sugarcane Yield and Health Be Altered with Fully Mechanized Management?
Jian Xiao, Tian Liang, Shangdong Yang, Hongwei Tan
Agronomy.2023; 13(1): 153. CrossRef
Evaluation of Various Escherichia coli Strains for Enhanced Lycopene Production
Jun Ren, Junhao Shen, Thi Duc Thai, Min-gyun Kim, Seung Ho Lee, Wonseop Lim, Dokyun Na
Journal of Microbiology and Biotechnology.2023; 33(7): 973. CrossRef
Effects of flavonoids on membrane adaptation of food-associated bacteria
Maria Linden, Alexander Flegler, Michelle M. Feuereisen, Fabian Weber, André Lipski, Andreas Schieber
Biochimica et Biophysica Acta (BBA) - Biomembranes.2023; 1865(4): 184137. CrossRef
Four new Microbacterium species isolated from seaweeds and reclassification of five Microbacterium species with a proposal of Paramicrobacterium gen. nov. under a genome-based framework of the genus Microbacterium
Soon Dong Lee, Hong Lim Yang, In Seop Kim
Frontiers in Microbiology.2023;[Epub] CrossRef
Microbacterium Cluster EA Bacteriophages: Phylogenomic Relationships and Host Range Predictions
Mark Milhaven, Cyril J. Versoza, Aman Garg, Lindsey Cai, Sanjana Cherian, Kamalei Johnson, Kevin Salas Perez, Madison Blanco, Jackelyn Lobatos, Corinne Mitra, Maria Strasser, Susanne P. Pfeifer
Microorganisms.2023; 11(1): 170. CrossRef
Valid publication of new names and new combinations effectively published outside the IJSEM. Validation List no. 203
Aharon Oren, George M. Garrity
International Journal of Systematic and Evolutionary Microbiology .2022;[Epub] CrossRef

Characterization of a novel dsRNA mycovirus of Trichoderma atroviride NFCF377 reveals a member of “Fusagraviridae” with changes in antifungal activity of the host fungus: Jeesun Chun , Byeonghak Na , Dae-Hyuk Kim; J. Microbiol. 2020;58(12):1046-1053. Published online October 23, 2020; DOI: https://doi.org/10.1007/s12275-020-0380-1

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Abstract PDF

Trichoderma atroviride is a common fungus found in various ecosystems that shows mycoparasitic ability on other fungi. A novel dsRNA virus was isolated from T. atroviride NFCF377 strain and its molecular features were analyzed. The viral genome consists of a single segmented double-stranded RNA and is 9,584 bp in length, with two discontinuous open reading frames (ORF1 and ORF2). A mycoviral structural protein and an RNA-dependent RNA polymerase (RdRp) are encoded by ORF1 and ORF2, respectively, between which is found a canonical shifty heptameric signal motif (AAAAAAC) followed by an RNA pseudoknot. Analysis of sequence similarity and phylogeny showed that it is closely related to members of the proposed family “Fusagraviridae”, with a highest similarity to the Trichoderma atroviride mycovirus 1 (TaMV1). Although the sequence similarity of deduced amino acid to TaMV1 was evident, sequence deviations were distinctive at untranslated regions (UTRs) due to the extended size. Thus, we inferred this dsRNA to be a different strain of Trichoderma atroviride mycovirus 1 (TaMV1-NFCF377). Electron microscopy image exhibited an icosahedral viral particle of 40 nm diameter. Virus-cured isogenic isolates were generated and no differences in growth rate, colony morphology, or conidia production were observed between virus-infected and virus-cured strains. However, culture filtrates of TaMV1- NFCF377-infected strain showed enhanced antifungal activity against the plant pathogen Rhizoctonia solani but not to edible mushroom Pleurotus ostreatus. These results suggested that TaMV1-NFCF377 affected the metabolism of the fungal host to potentiate antifungal compounds against a plant pathogen, but this enhanced antifungal activity appeared to be species-specific.

Citations

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Molecular characteristics of a novel alternavirus from Trichoderma harzianum
Jeesun Chun, Yo-Han Ko, Dae-Hyuk Kim
Archives of Virology.2026;[Epub] CrossRef
Complete genome sequence of a novel endornavirus from Rhizoctonia solani AG-1 IA isolate MY-JK-1
Shanshan Xu, Zhenmeng Zhou, Chengmeng Shen, Li Luo, Genhua Yang
Archives of Virology.2025;[Epub] CrossRef
Mycoviruses in Entomopathogenic Fungi
Matheus da Silva Camargo, Sam Edwards, Maressa O. Henrique, Urja Solanki, Tae Young Shin, Bo Huang, Henrik H. De Fine Licht, Marcio C. Silva-Filho, Augusto Schrank, Robert H. A. Coutts, Ioly Kotta-Loizou
Viruses.2025; 17(12): 1593. CrossRef
Co-infection with two novel mycoviruses affects the biocontrol activity of Trichoderma polysporum
Jeesun Chun, Hae-Ryeong Yoon, Sei-Jin Lee, Dae-Hyuk Kim
Biological Control.2024; 188: 105440. CrossRef
An Outstandingly Rare Occurrence of Mycoviruses in Soil Strains of the Plant-Beneficial Fungi from the Genus Trichoderma and a Novel Polymycoviridae Isolate
Chenchen Liu, Xiliang Jiang, Zhaoyan Tan, Rongqun Wang, Qiaoxia Shang, Hongrui Li, Shujin Xu, Miguel A. Aranda, Beilei Wu, Lea Atanasova
Microbiology Spectrum.2023;[Epub] CrossRef
Sixteen Novel Mycoviruses Containing Positive Single-Stranded RNA, Double-Stranded RNA, and Negative Single-Stranded RNA Genomes Co-Infect a Single Strain of Rhizoctonia zeae
Siwei Li, Zhihao Ma, Xinyi Zhang, Yibo Cai, Chenggui Han, Xuehong Wu
Journal of Fungi.2023; 10(1): 30. CrossRef
Trichoderma – genomes and genomics as treasure troves for research towards biology, biotechnology and agriculture
Miriam Schalamun, Monika Schmoll
Frontiers in Fungal Biology.2022;[Epub] CrossRef
A Transfectable Fusagravirus from a Japanese Strain of Cryphonectria carpinicola with Spherical Particles
Subha Das, Sakae Hisano, Ana Eusebio-Cope, Hideki Kondo, Nobuhiro Suzuki
Viruses.2022; 14(8): 1722. CrossRef
Molecular characteristics of a novel hypovirus from Trichoderma harzianum
Jeesun Chun, Kum-Kang So, Yo-Han Ko, Dae-Hyuk Kim
Archives of Virology.2022; 167(1): 233. CrossRef
Sustainable Management of Medicago sativa for Future Climates: Insect Pests, Endophytes and Multitrophic Interactions in a Complex Environment
Mark R. McNeill, Xiongbing Tu, Eric Altermann, Wu Beilei, Shengjing Shi
Frontiers in Agronomy.2022;[Epub] CrossRef
A New Double-Stranded RNA Mycovirus in Cryphonectria naterciae Is Able to Cross the Species Barrier and Is Deleterious to a New Host
Carolina Cornejo, Sakae Hisano, Helena Bragança, Nobuhiro Suzuki, Daniel Rigling
Journal of Fungi.2021; 7(10): 861. CrossRef

The response of human bacteria to static magnetic field and radiofrequency electromagnetic field: David P. E. Crabtree , Brandon J. Herrera , Sanghoon Kang; J. Microbiol. 2017;55(10):809-815. Published online September 28, 2017; DOI: https://doi.org/10.1007/s12275-017-7208-7

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Abstract PDF

Cell phones and electronic appliances and devices are inseparable from most people in modern society and the electromagnetic field (EMF) from the devices is a potential health threat. Although the direct health effect of a cell phone and its radiofrequency (RF) EMF to human is still elusive, the effect to unicellular organisms is rather apparent. Human microbiota, including skin microbiota, has been linked to a very significant role in the health of a host human body. It is important to understand the response of human skin microbiota to the RF-EMF from cell phones and personal electronic devices, since this may be one of the potential mechanisms of a human health threat brought about by the disruption of the intimate and balanced host-microbiota relationship. Here, we investigated the response of both laboratory culture strains and isolates of skin bacteria under static magnetic field (SMF) and RF-EMF. The growth patterns of laboratory cultures of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus epidermidis under SMF were variable per different species. The bacterial isolates of skin microbiota from 4 subjects with different cell phone usage history also showed inconsistent growth responses. These findings led us to hypothesize that cell phone level RF-EMF disrupts human skin microbiota. Thus, the results from the current study lay ground for more comprehensive research on the effect of RF-EMF on human health through the human-microbiota relationship.

Citations

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The Effect of Exposure to an Electromagnetic Field on Entomopathogenic Fungi
Dariusz Roman Ropek, Krzysztof Frączek, Krzysztof Pawlak, Karol Bulski, Magdalena Ludwiczak
Applied Sciences.2024; 14(24): 11508. CrossRef
Effects of non-ionizing electromagnetic fields on flora and fauna, Part 2 impacts: how species interact with natural and man-made EMF
B. Blake Levitt, Henry C. Lai, Albert M. Manville
Reviews on Environmental Health.2022; 37(3): 327. CrossRef
Natural and Synthetic Halogenated Amino Acids—Structural and Bioactive Features in Antimicrobial Peptides and Peptidomimetics
Mario Mardirossian, Marina Rubini, Mauro F. A. Adamo, Marco Scocchi, Michele Saviano, Alessandro Tossi, Renato Gennaro, Andrea Caporale
Molecules.2021; 26(23): 7401. CrossRef
Biological Effects of a Low-Frequency Electromagnetic Field on Yeast Cells of the Genus Saccharomyces Cerevisiae
K Sladicekova, M Bereta, J Misek, D Parizek, J Jakus
Acta Medica Martiniana.2021; 21(2): 34. CrossRef
Effects of radiofrequency electromagnetic radiation on the organism as a whole and structural units (Literature review)
Rano Z. Lifanova, Valentina S. Orlova, Vladimir V. Tsetlin
Hygiene and sanitation.2021; 100(2): 123. CrossRef
Effects of Electromagnetic Waves with LTE and 5G Bandwidth on the Skin Pigmentation In Vitro
Kyuri Kim, Young Seung Lee, Nam Kim, Hyung-Do Choi, Dong-Jun Kang, Hak Rim Kim, Kyung-Min Lim
International Journal of Molecular Sciences.2020; 22(1): 170. CrossRef
Global gene expression analysis of Escherichia coli K-12 DH5α after exposure to 2.4 GHz wireless fidelity radiation
Ilham H. Said-Salman, Fatima A. Jebaii, Hoda H. Yusef, Mohamed E. Moustafa
Scientific Reports.2019;[Epub] CrossRef
Towards 5G communication systems: Are there health implications?
Agostino Di Ciaula
International Journal of Hygiene and Environmental Health.2018; 221(3): 367. CrossRef

Characteristics of the community-genotype sequence type 72 methicillin-resistant Staphylococcus aureus isolates that underlie their persistence in hospitals: Eun-Jeong Joo , Ji-Young Choi , Doo Ryeon Chung , Jae-Hoon Song , Kwan Soo Ko; J. Microbiol. 2016;54(6):445-450. Published online May 27, 2016; DOI: https://doi.org/10.1007/s12275-016-6157-x

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Abstract PDF

Panton-Valentine leukocidin-negative methicillin-resistant Staphylococcus aureus (MRSA) clone ST72, known as a major community-associated MRSA in Korea, has emerged as an important pathogen in hospitals. To understand bacterial properties that underlie transformation of this clone into a nosocomial pathogen, we compared characteristics of the community-genotype ST72 MRSA isolates with those of ST5 and ST239 MRSA, which have been predominant nosocomial MRSA clones in Korea. Several genes associated with adhesion and virulence were absent or rarely found in ST72 isolates. Many ST72 isolates (70.1%) belonged to agr group I, but the agr group of other ST72 isolates could not be determined. As indicated by δ-hemolysin production, ST72 isolates expressed fully functional agr, whereas agr dysfunction was observed in ST5 and ST239 isolates. In the biofilm formation assay, no upregulation of biofilm-forming activity of ST72 MRSA was detected. However, ST72 isolates demonstrated persistence under hypotonic and desiccating conditions (survival rates 72.3% and 33.9%, respectively), which was similar to characteristics of ST5 or ST239 isolates. ST72- MRSA isolates showed low virulence, but properties of their functional agr system could facilitate their spread in hospitals. In conclusion, tolerance to stressful environments, e.g., hypotonic and dry conditions, may also contribute to survival of the community-associated MRSA clones in healthcare facilities.

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Sara Teixeira, Beatriz Ramos, Mónica V Cunha
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José R. W. Martínez, Paul J. Planet, Maria Spencer-Sandino, Lina Rivas, Lorena Díaz, Ahmed M. Moustafa, Ana Quesille-Villalobos, Roberto Riquelme-Neira, Manuel Alcalde-Rico, Blake Hanson, Lina P. Carvajal, Sandra Rincón, Jinnethe Reyes, Marusella Lam, Jua
Microbiology Spectrum.2023;[Epub] CrossRef
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You-Jin Hwang
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Jun Sung Hong, Dokyun Kim, Seok Hoon Jeong
Antibiotics.2022; 11(7): 909. CrossRef
Comparative Genomic Analysis Provides Insights into the Evolution and Genetic Diversity of Community-Genotype Sequence Type 72 Staphylococcus aureus Isolates
Wangxiao Zhou, Ye Jin, Yanzi Zhou, Yuan Wang, Luying Xiong, Qixia Luo, Yonghong Xiao, Suleyman Yildirim
mSystems.2021;[Epub] CrossRef
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Hyemin Chung, Eunsil Kim, Eunmi Yang, Yun Woo Lee, Joung Ha Park, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim
European Journal of Clinical Microbiology & Infectious Diseases.2021; 40(12): 2497. CrossRef
Genome-Wide Analysis of Staphylococcus aureus Sequence Type 72 Isolates Provides Insights Into Resistance Against Antimicrobial Agents and Virulence Potential
Nayab Batool, Amen Shamim, Akhilesh Kumar Chaurasia, Kyeong Kyu Kim
Frontiers in Microbiology.2021;[Epub] CrossRef
A Longitudinal Study of Adult Patients withStaphylococcus aureusBacteremia over 11 Years in Korea
Seong-Ho Choi, Jeongsoo Lee, Jiwon Jung, Eun Sil Kim, Min Jae Kim, Yong Pil Chong, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Jun Hee Woo, Yang Soo Kim
Journal of Korean Medical Science.2021;[Epub] CrossRef
Changing characteristics of S. aureus bacteremia caused by PVL-negative, MRSA strain over 11 years
Eunmi Yang, Eunsil Kim, Hyemin Chung, Yun Woo Lee, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sung-Han Kim, Sang-Ho Choi, Sang-Oh Lee, Yang Soo Kim
Scientific Reports.2021;[Epub] CrossRef
Functional Identification of Serine Hydroxymethyltransferase as a Key Gene Involved in Lysostaphin Resistance and Virulence Potential of Staphylococcus aureus Strains
Nayab Batool, Kwan Soo Ko, Akhilesh Kumar Chaurasia, Kyeong Kyu Kim
International Journal of Molecular Sciences.2020; 21(23): 9135. CrossRef
Sterilization efficiency of pathogen-contaminated cottons in a laundry machine
Yoonjae Shin, Jungha Park, Woojun Park
Journal of Microbiology.2020; 58(1): 30. CrossRef
Clinical S. aureus Isolates Vary in Their Virulence to Promote Adaptation to the Host
Lorena Tuchscherr, Christine Pöllath, Anke Siegmund, Stefanie Deinhardt-Emmer, Verena Hoerr, Carl-Magnus Svensson, Marc Thilo Figge, Stefan Monecke, Bettina Löffler
Toxins.2019; 11(3): 135. CrossRef
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Eunsin Bae, Choon Kwan Kim, Jung-Hyun Jang, Heungsup Sung, YounMi Choi, Mi-Na Kim
Annals of Laboratory Medicine.2019; 39(2): 158. CrossRef
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Yae Sung Mun, You Jin Hwang
Antibiotics.2019; 8(4): 202. CrossRef
Emergence of Community-Genotype Methicillin-ResistantStaphylococcus aureusin Korean Hospitals: Clinical Characteristics of Nosocomial Infections by Community-Genotype Strain
Eun-Jeong Joo, Doo Ryeon Chung, So Hyun Kim, Jin Yang Baek, Nam Yong Lee, Sun Young Cho, Young Eun Ha, Cheol-In Kang, Kyong Ran Peck, Jae-Hoon Song
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So Yeon Park, Doo Ryeon Chung, Yu Ri Kang, So Hyun Kim, Sun Young Cho, Young Eun Ha, Cheol-In Kang, Kyong Ran Peck, Jae-Hoon Song
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Jung Wook Kim, Gi Su Kang, Jae Il Yoo, Hwa Su Kim, Yeong Seon Lee, Jae-Yon Yu, Kwang-Jun Lee, Chan Park, Il-Hwan Kim
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