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NOTE] Isolation and Characterization of Self-Fertile Suppressors from the Sterile nsdD Deletion Mutant of Aspergillus nidulans
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Research Support, Non-U.S. Gov't
NOTE] Isolation and Characterization of Self-Fertile Suppressors from the Sterile nsdD Deletion Mutant of Aspergillus nidulans
Dong-Beom Lee 1, Lee Han Kim 1, Jin-Pyo Kim 2, Kap-Hoon Han 2, Dong-Min Han 1
Journal of Microbiology 2011;49(6):1054-1057
DOI: https://doi.org/10.1007/s12275-011-1111-4
Published online: December 28, 2011
1Division of Life Science, Wonkwang University, Iksan 570-749, Republic of Korea, 2Department of Pharmaceutical Engineering, Woosuk University, Wanju 565-701, Republic of Korea1Division of Life Science, Wonkwang University, Iksan 570-749, Republic of Korea, 2Department of Pharmaceutical Engineering, Woosuk University, Wanju 565-701, Republic of Korea
Corresponding author:  Kap-Hoon Han , Tel: +82-63-290-1427, 
Dong-Min Han , Tel: +82-63-850-6220, 
Received: 7 March 2011   • Accepted: 21 July 2011
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Abstract

To identify downstream and/or interactive factors of the nsdD gene, which encodes a positive regulator of sexual development of Aspergillus nidulans, suppressor mutants displaying a self-fertile phenotype were isolated from a sterile nsdD deletion mutant. At least five different loci (sndA-E) were identified and genetically analyzed. In the nsdD+ background, most of the suppressors showed a marked increment of sexual development, even under the stress conditions that normally inhibited sexual development. The common phenotype of the suppressor mutants suggested the involvement of the snd genes in the negative regulation of sexual development in response to the environmental factors.

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    NOTE] Isolation and Characterization of Self-Fertile Suppressors from the Sterile nsdD Deletion Mutant of Aspergillus nidulans
    J. Microbiol. 2011;49(6):1054-1057.   Published online December 28, 2011
    DOI: https://doi.org/10.1007/s12275-011-1111-4
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