Antibacterial Characteristics of Curcuma xanthorrhiza Extract on Streptococcus mutans Biofilm

Jung-Eun Kim; Hee-Eun Kim; Jae-Kwan Hwang; Ho-Jeong Lee; Ho-Keun Kwon; Baek-Il Kim

doi:10.1007/s12275-007-0167-7

Articles

Page Path: HOME > J. Microbiol > Volume 46(2); 2008 > Article

Research Support, Non-U.S. Gov't
Antibacterial Characteristics of Curcuma xanthorrhiza Extract on Streptococcus mutans Biofilm: Jung-Eun Kim ^1,2,3, Hee-Eun Kim ^1,2,3, Jae-Kwan Hwang ⁴, Ho-Jeong Lee ^1,2,3, Ho-Keun Kwon ^1,2,3, Baek-Il Kim ^1,2,3; Journal of Microbiology 2008;46(2):228-232.
DOI: https://doi.org/10.1007/s12275-007-0167-7
Published online: June 11, 2008

¹Department of Preventive Dentistry and Public Oral Health, Yonsei University, Seoul 120-752, Republic of Korea, ²Research Center for Orofacial Hard Tissue Regeneration, Yonsei University, Seoul 120-752, Republic of Korea, ³Brain Korea 21 project, Yonsei University, College of Dentistry, Yonsei University, Seoul 120-752, Republic of Korea, ⁴Department of Biotechnology and Bioproducts Research Center, Yonsei University, Seoul 120-752, Republic of Korea¹Department of Preventive Dentistry and Public Oral Health, Yonsei University, Seoul 120-752, Republic of Korea, ²Research Center for Orofacial Hard Tissue Regeneration, Yonsei University, Seoul 120-752, Republic of Korea, ³Brain Korea 21 project, Yonsei University, College of Dentistry, Yonsei University, Seoul 120-752, Republic of Korea, ⁴Department of Biotechnology and Bioproducts Research Center, Yonsei University, Seoul 120-752, Republic of Korea

Corresponding author: Baek-Il Kim , Tel: 82-2-2228-3072,

Received: 20 September 2007 • Accepted: 20 March 2008

prev next

55 Views
0 Download
38 Crossref
53 Scopus

Full Article

Abstract

This study evaluated the antibacterial effects of a natural Curcuma xanthorrhiza extract (Xan) on a Streptococcus mutans biofilm by examining the bactericidal activity, inhibition of acidogenesis and morphological alteration. Xan was obtained from the roots of a medicinal plant in Indonesia, which has shown selective

antibacterial effects on planktonic S. mutans. S. mutans biofilms were formed on slide glass over a 72 h period and treated with the following compounds for 5, 30, and 60 min: saline, 1% DMSO, 2 mg/ml chlorhexidine (CHX), and 0.1 mg/ml Xan. The Xan group exposed for 5 and 30 min showed significantly fewer colony forming units (CFU, 57.6 and 97.3%, respectively) than those exposed to 1% DMSO, the negative control group (P<0.05). These CFU were similar in number to those slides exposed to CHX, the positive control group. Xan showed similar bactericidal effect to that of CHX but the dose of Xan was one twentieth that of CHX. In addition, the biofilms treated with Xan and CHX maintained a neutral pH for 4 h, which indicates that Xan and CHX inhibit acid production. Scanning electron microscopy showed morphological changes in the cell wall and membrane of the Xan-treated biofilms; an uneven surface and a deformation in contour. Overall, natural Xan has strong bactericidal activity, inhibitory effects on acidogenesis, and alters the microstructure of S. mutans biofilm. In conclusion, Xan has potential in anti-S. mutans therapy for the prevention of dental caries.

Keywords: antibacterial effects;biofilms;Curcuma xanthorrhiza;Streptococcus mutans

Figure & Data

References

Citations

Citations to this article as recorded by

The efficacy of the food-grade antimicrobial xanthorrhizol against Staphylococcus aureus is associated with McsL channel expression
Elena A. Mordukhova, Jongwan Kim, Haiyan Jin, Kyoung Tai No, Jae-Gu Pan
Frontiers in Microbiology.2024;[Epub] CrossRef
Anti-biofilm activity of a novel nanoemulsion containing Curcuma xanthorrhiza oil
Mu-Yeol Cho, Eun-Song Lee, Hoi-In Jung, Baek-Il Kim
Journal of Dentistry.2023; 137: 104647. CrossRef
Étude de l’activité antimicrobienne du Curcuma longa sur le Streptococcus mutans isolé de lésions carieuses
N. Allal, W. Didi, H. Hassaine, F. Oudghiri, D. Bouziane
Phytothérapie.2022; 20(4-5): 248. CrossRef
Algal polysaccharide’s potential to combat respiratory infections caused by Klebsiella pneumoniae and Serratia marcescens biofilms
Jyoti Vishwakarma, Bhumika Waghela, Berness Falcao, Sirisha L. Vavilala
Applied Biochemistry and Biotechnology.2022; 194(2): 671. CrossRef
Herbo-dentistry- A review
Gautam Nandita, KK Shivalingesh, Singh Arjun, Singh Varnika, Rajpoot Deepshikha
Journal of Dental Problems and Solutions.2022; 9(1): 006. CrossRef
Antibacterial and Antimicrobial Effects of Xanthorrhizol in the Prevention of Dental Caries: A Systematic Review
Ghulam Sarwar Khalid, Mohammad Hassan Hamrah, Elaha Somaya Ghafary, Sepideh Hosseini, Fateme Almasi
Drug Design, Development and Therapy.2021; Volume 15: 1149. CrossRef
Galla Chinensis, a Traditional Chinese Medicine: Comprehensive review of botany, traditional uses, chemical composition, pharmacology and toxicology
Yuan-yuan Ren, Xiao-rui Zhang, Ting-na Li, Yi-jia Zeng, Jin Wang, Qin-wan Huang
Journal of Ethnopharmacology.2021; 278: 114247. CrossRef
Do natural ingredients in a dentifrice contribute to prevention of plaque and gingivitis?
Cees Valkenburg, N. A. Martijn Rosema, Nienke L. Hennequin‐Hoenderdos, Paula A. Versteeg, Dagmar Else Slot, G. A. (Fridus) Van der Weijden
International Journal of Dental Hygiene.2021; 19(4): 429. CrossRef
In vitro activities of Acacia nilotica (L.) Delile bark fractions against Oral Bacteria, Glucosyltransferase and as antioxidant
Ali Mahmoud Muddathir, Ebtihal Abdalla M. Mohieldin, Tohru Mitsunaga
BMC Complementary Medicine and Therapies.2020;[Epub] CrossRef
The food-grade antimicrobial xanthorrhizol targets the enoyl-ACP reductase (FabI) in Escherichia coli
Yogiara, Elena A. Mordukhova, Dooil Kim, Won-Gon Kim, Jae-Kwan Hwang, Jae-Gu Pan
Bioorganic & Medicinal Chemistry Letters.2020; 30(24): 127651. CrossRef
Antimicrobial activity of Curcuma xanthorrhiza nanoemulsions on Streptococcus mutans biofilms
Mu-Yeol Cho, Si-Mook Kang, Eun-Song Lee, Baek-Il Kim
Biofouling.2020; 36(7): 825. CrossRef
Antibacterial effect of different concentrations of Galla Chinensis extract on cariogenic bacteria in a biofilm model
Eun-Jeong Kim, Bo-Hyoung Jin
Journal of Korean Academy of Oral Health.2020; 44(1): 13. CrossRef
Biocompatibility and Antimicrobial Activity of Reynoutria elliptica Extract for Dental Application
Song-Yi Yang, Min-Kyung Kang
Plants.2020; 9(6): 670. CrossRef
Novel Dental Poly (Methyl Methacrylate) Containing Phytoncide for Antifungal Effect and Inhibition of Oral Multispecies Biofilm
Myung-Jin Lee, Min-Ji Kim, Sang-Hwan Oh, Jae-Sung Kwon
Materials.2020; 13(2): 371. CrossRef
Analysis of the Antimicrobial, Cytotoxic, and Antioxidant Activities of Cnidium officinale Extracts
Myung-Jin Lee, Min-Kyung Kang
Plants.2020; 9(8): 988. CrossRef
Inhibition of Pseudomonas aeruginosa Quorum Sensing by Curcuma xanthorrhiza Roxb. Extract
Ahmad Fiqri Mustaqim Othman, Yaya Rukayadi, Son Radu
Journal of Pure and Applied Microbiology.2019; 13(3): 1335. CrossRef
Expansion of antibacterial spectrum of xanthorrhizol against Gram-negatives in combination with PMBN and food-grade antimicrobials
Man Su Kim, Ha-Rim Kim, Haebom Kim, Soo-Keun Choi, Chang-Hwan Kim, Jae-Kwan Hwang, Seung-Hwan Park
Journal of Microbiology.2019; 57(5): 405. CrossRef
Galla chinensisextracts and calcium induce remineralization and antibacterial effects of enamel in aStreptococcus mutansbiofilm model
Eun-Jeong Kim, Bo-Hyoung Jin
Journal of Korean Academy of Oral Health.2018; 42(3): 90. CrossRef
Tooth enamel surface micro-hardness with dual species Streptococcus biofilm after exposure to Java turmeric (Curcuma xanthorrhiza Roxb.) extract
F R G Isjwara, S N Hasanah, Sri Utami, D F Suniarti
Journal of Physics: Conference Series.2017; 884: 012012. CrossRef
Antibacterial Inhibitory Effects of Punica Granatum Gel on Cariogenic Bacteria: An in vitro Study
Grazielle Millo, Apa Juntavee, Ariya Ratanathongkam, Natsajee Nualkaew, Peerapattana, Jomjai, Supaporn Chatchiwiwattana
International Journal of Clinical Pediatric Dentistry.2017; 10(2): 152. CrossRef
Antibacterial photodynamic therapy with curcumin and Curcuma xanthorrhiza extract against Streptococcus mutans
Hyung-Jung Lee, Si-Mook Kang, Seung-Hwa Jeong, Ki-Ho Chung, Baek-Il Kim
Photodiagnosis and Photodynamic Therapy.2017; 20: 116. CrossRef
Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms
Lamprini Karygianni, Ali Al-Ahmad, Aikaterini Argyropoulou, Elmar Hellwig, Annette C. Anderson, Alexios L. Skaltsounis
Frontiers in Microbiology.2016;[Epub] CrossRef
Sub-Optimal Treatment of Bacterial Biofilms
Tianyan Song, Marylise Duperthuy, Sun Wai
Antibiotics.2016; 5(2): 23. CrossRef
Fabrication and In Vitro/In Vivo Performance of Mucoadhesive Electrospun Nanofiber Mats Containing α-Mangostin
Wipada Samprasit, Theerasak Rojanarata, Prasert Akkaramongkolporn, Tanasait Ngawhirunpat, Ruchadaporn Kaomongkolgit, Praneet Opanasopit
AAPS PharmSciTech.2015; 16(5): 1140. CrossRef
Phytodentistry: use of medicinal plants
Kavita Hotwani, Sudhindra Baliga, Krishna Sharma
Journal of Complementary and Integrative Medicine.2014; 11(4): 233. CrossRef
Recent advances on the beneficial use and health implications of Pu-Erh tea
L.K. Lee, K.Y. Foo
Food Research International.2013; 53(2): 619. CrossRef
Inhibitory Effect ofDodonaea viscosavar.angustifoliaon the Virulence Properties of the Oral PathogensStreptococcus mutansandPorphyromonas gingivalis
Mrudula Patel, Roxanne Naidoo, Foluso John Owotade
Evidence-Based Complementary and Alternative Medicine.2013; 2013: 1. CrossRef
Effectiveness of Antimicrobial Solutions on Streptococcus mutans in used Toothbrushes
Padma K Bhat, Soumik Sarkar, Sandhya Chengappa, Nithin N Bhaskar
World Journal of Dentistry.2012; 3(1): 6. CrossRef
Streptococcus mutansandStreptococcus sobrinusbiofilm formation and metabolic activity on dental materials
Sebastian Hahnel, Gudrun Mühlbauer, Judith Hoffmann, Andrei Ionescu, Ralf Bürgers, Martin Rosentritt, Gerhard Handel, Ingo Häberlein
Acta Odontologica Scandinavica.2012; 70(2): 114. CrossRef
Inhibitory activity of Dodonaea viscosa var. angustifolia extract against Streptococcus mutans and its biofilm
Roxanne Naidoo, Mrudula Patel, Zandiswa Gulube, Ildi Fenyvesi
Journal of Ethnopharmacology.2012; 144(1): 171. CrossRef
Effect of Marinating Chicken Meat with Lemon, Green Tea and Turmeric Against Foodborne Bacterial Pathogens
N. Murali, G.S. Kumar-Phil, N.C. Rath, J. Marcy, M.F. Slavik
International Journal of Poultry Science.2012; 11(5): 326. CrossRef
Antibacterial property and mechanism of a novel Pu-erh tea nanofibrous membrane
Yajuan Su, Chenlu Zhang, Yan Wang, Ping Li
Applied Microbiology and Biotechnology.2012; 93(4): 1663. CrossRef
Antimicrobial actions of α-mangostin against oral streptococci
Phuong T. M. Nguyen, Robert E. Marquis
Canadian Journal of Microbiology.2011; 57(3): 217. CrossRef
Revealing Indigenous Indonesian Traditional Medicine: Anti-infective Agents
Ari S. Nugraha, Paul A. Keller
Natural Product Communications.2011;[Epub] CrossRef
Novel compound from Trachyspermum ammi (Ajowan caraway) seeds with antibiofilm and antiadherence activities against Streptococcus mutans: a potential chemotherapeutic agent against dental caries
R. Khan, M. Zakir, Z. Khanam, S. Shakil, A.U. Khan
Journal of Applied Microbiology.2010; 109(6): 2151. CrossRef
Understanding antimicrobial activities of phytochemicals against multidrug resistant bacteria and biofilms
Manuel Simões, Richard N. Bennett, Eduardo A. S. Rosa
Natural Product Reports.2009; 26(6): 746. CrossRef
Activity of panduratin A isolated from Kaempferia pandurata Roxb. against multi-species oral biofilms in vitro
Yaya Rukayadi, Kwan-Hyoung Lee, Jae-Kwan Hwang
Journal of Oral Science.2009; 51(1): 87. CrossRef
Inhibitory effect of methyl gallate and gallic acid on oral bacteria
Mi-Sun Kang, Jong-Suk Oh, In-Chol Kang, Suk-Jin Hong, Choong-Ho Choi
The Journal of Microbiology.2008; 46(6): 744. CrossRef

Cite this Article

Cite this Article: export Copy Download Format; Close

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
BibTeX — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

Antibacterial Characteristics of Curcuma xanthorrhiza Extract on Streptococcus mutans Biofilm

J. Microbiol. 2008;46(2):228-232. Published online June 11, 2008

DOI: https://doi.org/10.1007/s12275-007-0167-7

Related articles