Journal of Microbiology

Journal Articles

[PROTOCOL]Analyzing viral epitranscriptomes using nanopore direct RNA sequencing: Ari Hong , Dongwan Kim , V. Narry Kim , Hyeshik Chang; J. Microbiol. 2022;60(9):867-876. Published online August 24, 2022; DOI: https://doi.org/10.1007/s12275-022-2324-4

55 View
0 Download
7 Web of Science
7 Crossref

RNA modifications are a common occurrence across all domains of life. Several chemical modifications, including N6- methyladenosine, have also been found in viral transcripts and viral RNA genomes. Some of the modifications increase the viral replication efficiency while also helping the virus to evade the host immune system. Nonetheless, there are numerous examples in which the host's RNA modification enzymes function as antiviral factors. Although established methods like MeRIP-seq and miCLIP can provide a transcriptome- wide overview of how viral RNA is modified, it is difficult to distinguish between the complex overlapping viral transcript isoforms using the short read-based techniques. Nanopore direct RNA sequencing (DRS) provides both long reads and direct signal readings, which may carry information about the modifications. Here, we describe a refined protocol for analyzing the RNA modifications in viral transcriptomes using nanopore technology.

Citations

Citations to this article as recorded by

Utilization of nanopore direct RNA sequencing to analyze viral RNA modifications
Lu Tan, Zhihao Guo, Xiaoming Wang, Dal Young Kim, Runsheng Li, Pedro H. Oliveira
mSystems.2024;[Epub] CrossRef
Current progress in strategies to profile transcriptomic m6A modifications
Yuening Yang, Yanming Lu, Yan Wang, Xianghui Wen, Changhai Qi, Weilan Piao, Hua Jin
Frontiers in Cell and Developmental Biology.2024;[Epub] CrossRef
Improved sub-genomic RNA prediction with the ARTIC protocol
Thomas Baudeau, Kristoffer Sahlin
Nucleic Acids Research.2024; 52(17): e82. CrossRef
Non-Targeted RNA Sequencing: Towards the Development of Universal Clinical Diagnosis Methods for Human and Veterinary Infectious Diseases
Stephen Spatz, Claudio L. Afonso
Veterinary Sciences.2024; 11(6): 239. CrossRef
Quantitative profiling N1-methyladenosine (m1A) RNA methylation from Oxford nanopore direct RNA sequencing data
Shenglun Chen, Jia Meng, Yuxin Zhang
Methods.2024; 228: 30. CrossRef
Multicellular, IVT-derived, unmodified human transcriptome for nanopore-direct RNA analysis
Caroline A. McCormick, Stuart Akeson, Sepideh Tavakoli, Dylan Bloch, Isabel N. Klink, Miten Jain, Sara H. Rouhanifard
Gigabyte.2024; 2024: 1. CrossRef
Dissecting the effects of METTL3 on alternative splicing in prostate cancer
Lin Wang, Ling Shi, Yonghao Liang, Judy Kin-Wing Ng, Chan Hoi Yin, Lingyi Wang, Jinpao Hou, Yiwei Wang, Cathy Sin-Hang Fung, Peter Ka-Fung Chiu, Chi-Fai Ng, Stephen Kwok-Wing Tsui
Frontiers in Oncology.2023;[Epub] CrossRef

Whole-genome sequencing analysis of Shiga toxin-producing Escherichia coli O22:H8 isolated from cattle prediction pathogenesis and colonization factors and position in STEC universe phylogeny: Wanderson Marques Da Silva , Mariano Larzabal , Flavia Figueira Aburjaile , Nahuel Riviere , Luisina Martorelli , James Bono , Ariel Amadio , Angel Cataldi; J. Microbiol. 2022;60(7):689-704. Published online June 22, 2022; DOI: https://doi.org/10.1007/s12275-022-1616-z

50 View
0 Download
5 Web of Science
4 Crossref

Abstract

Shiga toxin-producing Escherichia coli (STEC) is a foodborne pathogen capable of causing illness in humans. In a previous study, our group showed that a STEC isolate belonging to O22:H8 serotype (strain 154) can interfere with STEC O157:H7 colonization both in vitro and in vivo. Using whole-genome sequencing and genomic comparative, we predicted a subset of genes acquired by O22:H8 strain 154 through horizontal gene transfer that might be responsible for the phenotype previously described by our group. Among them were identified genes related to the pathogenesis of non-LEE (locus of enterocyte effacement) STEC, specific metabolic processes, antibiotic resistance and genes encoding for the T6SS-1 that is related to inter-bacterial competition. In addition, we showed that this strain carries stx1c and stx2dact, a mucus-inducible variant. The results obtained in this study provide insights into STEC genomic plasticity and the importance of genomic islands in the adaptation and pathogenesis of this pathogen.

Citations

Citations to this article as recorded by

MEGARes and AMR++, v3.0: an updated comprehensive database of antimicrobial resistance determinants and an improved software pipeline for classification using high-throughput sequencing
Nathalie Bonin, Enrique Doster, Hannah Worley, Lee J Pinnell, Jonathan E Bravo, Peter Ferm, Simone Marini, Mattia Prosperi, Noelle Noyes, Paul S Morley, Christina Boucher
Nucleic Acids Research.2023; 51(D1): D744. CrossRef
Genomes-based MLST, cgMLST, wgMLST and SNP analysis of Salmonella Typhimurium from animals and humans
Shigan Yan, Zhaoxu Jiang, Wencheng Zhang, Zhenhai Liu, Xiaorui Dong, Donghui Li, Zijun Liu, Chengyu Li, Xu Liu, Liping Zhu
Comparative Immunology, Microbiology and Infectious Diseases.2023; 96: 101973. CrossRef
Escherichia coli O157:H7 tir 255 T > A allele strains differ in chromosomal and plasmid composition
Margaret D. Weinroth, Michael L. Clawson, Gregory P. Harhay, Mark Eppinger, Dayna M. Harhay, Timothy P. L. Smith, James L. Bono
Frontiers in Microbiology.2023;[Epub] CrossRef
Occurrence and genetic characterization of Shiga toxin-producing Escherichia coli on bovine and pork carcasses and the environment from transport trucks
Rocío Colello, Manuela Baigorri, Felipe Del Canto, Juliana González, Ariel Rogé, Claudia van der Ploeg, Federico Sánchez Chopa, Mónica Sparo, Analía Etcheverría, Nora Lía Padola
World Journal of Microbiology and Biotechnology.2023;[Epub] CrossRef

Lipocalin2 as a potential antibacterial drug against Acinetobacter baumannii infection: Daejin Lim , Su-Jin Park , Ha Young Kim , Minsang Shin , Miryoung Song; J. Microbiol. 2022;60(4):444-449. Published online March 28, 2022; DOI: https://doi.org/10.1007/s12275-022-2007-1

61 View
0 Download
3 Web of Science
3 Crossref

Abstract

Available antibiotics to treat Acinetobacter baumannii infection is limited due to increasing resistance and the emergence of multiple drug-resistant strains. Hence, discovering effective agents against A. baumannii to reduce the number of infectionrelated deaths is imperative. In search of novel and alternative antibiotics, the antibacterial function of lipocalin2 (Lcn2) was investigated to treat systemic infections of A. baumannii using a mouse neutropenia model. We observed a significant increase in serum Lcn2 levels upon bacterial injection into the mouse, and the administration of recombinant Lcn2 (rmLcn2) extended their survival. Such protective effects were also observed in rmLcn2-pretreated macrophages, where rmLcn2 reduced the survival of the pathogen inside the macrophages. The underlying molecular mechanism of Lcn2 protection was also investigated. We observed that pretreatment of the Raw- 264.7 macrophages with rmLcn2 markedly altered the expression of tonB3, which encodes a component of the transporter for ferrisiderophores in A. baumannii. However, the expression of katG, the gene encoding catalase, remained unaffected. These indicate that Lcn2-mediated defense against the pathogen is related to nutritional immunity rather than reactive oxygen species (ROS) production. Furthermore, the addition of rmLcn2 in infected mice diminished bacterial burden in multiple organs and enhanced the expression of tonB3 in the liver, spleen, and lungs of the infected mice. Increased survival rate due to rmLcn2 treatment declined when the infection model was established using lcn2-defective (lcn2-/-) mice, which indicated the necessity of endogenous Lcn2. Therefore, the antibacterial function of Lcn2 can be exploited to develop an alternative therapeutic agent against A. baumannii.

Citations

Citations to this article as recorded by

Antimicrobial peptide thanatin fused endolysin PA90 (Tha-PA90) for the control of Acinetobacter baumannii infection in mouse model
Jeonghyun Lim, Heejoon Myung, Daejin Lim, Miryoung Song
Journal of Biomedical Science.2024;[Epub] CrossRef
Dynamic changes and clinical value of lipocalin 2 in liver diseases caused by microbial infections
Feng Chen, Shan-Shan Wu, Chao Chen, Cheng Zhou
World Journal of Hepatology.2024; 16(2): 177. CrossRef
Lipocalin-2 is an essential component of the innate immune response to Acinetobacter baumannii infection
Jessica R. Sheldon, Lauren E. Himmel, Dillon E. Kunkle, Andrew J. Monteith, K. Nichole Maloney, Eric P. Skaar, David S. Weiss
PLOS Pathogens.2022; 18(9): e1010809. CrossRef

Gold nanoparticle-DNA aptamer-assisted delivery of antimicrobial peptide effectively inhibits Acinetobacter baumannii infection in mice: Jaeyeong Park , Eunkyoung Shin , Ji-Hyun Yeom , Younkyung Choi , Minju Joo , Minho Lee , Je Hyeong Kim , Jeehyeon Bae , Kangseok Lee; J. Microbiol. 2022;60(1):128-136. Published online December 29, 2021; DOI: https://doi.org/10.1007/s12275-022-1620-3

137 View
0 Download
14 Web of Science
15 Crossref

Abstract

Acinetobacter baumannii causes multidrug resistance, leading to fatal infections in humans. In this study, we showed that Lys AB2 P3-His–a hexahistidine-tagged form of an antimicrobial peptide (AMP) loaded onto DNA aptamer-functionalized gold nanoparticles (AuNP-Apt)–can effectively inhibit A. baumannii infection in mice. When A. baumannii-infected mice were intraperitoneally injected with AuNP-Apt loaded with Lys AB2 P3-His, a marked reduction in A. baumannii colonization was observed in the mouse organs, leading to prominently increased survival time and rate of the mice compared to those of the control mice treated with AuNP-Apt or Lys AB2 P3-His only. This study shows that AMPs loaded onto AuNP-Apt could be an effective therapeutic tool against infections caused by multidrug-resistant pathogenic bacteria in humans.

Citations

Citations to this article as recorded by

Challenges and Emerging Molecular Approaches in Combating Antimicrobial Resistance
Gene Philip Levee Ynion, Christian Jay Rosal, Arvin Zulueta, Angelo Ordanel, Christopher Marlowe Caipang
Journal of Bacteriology and Virology.2024; 54(1): 12. CrossRef
Gold Nanoparticles and Antimicrobial Peptides: A Novel Combination
Şule Balcı, Bengü Ergüden
ChemistrySelect.2024;[Epub] CrossRef
Aptamers: A Cutting-Edge Approach for Gram-Negative Bacterial Pathogen Identification
María Guadalupe Córdova-Espinoza, Rosa González-Vázquez, Rolando Rafik Barron-Fattel, Raquel Gónzalez-Vázquez, Marco Antonio Vargas-Hernández, Exsal Manuel Albores-Méndez, Ana Laura Esquivel-Campos, Felipe Mendoza-Pérez, Lino Mayorga-Reyes, María Angélica
International Journal of Molecular Sciences.2024; 25(2): 1257. CrossRef
Antimicrobial Peptide Delivery Systems as Promising Tools Against Resistant Bacterial Infections
Kamila Botelho Sampaio de Oliveira, Michel Lopes Leite, Nadielle Tamires Moreira Melo, Letícia Ferreira Lima, Talita Cristina Queiroz Barbosa, Nathalia Lira Carmo, Douglas Afonso Bittencourt Melo, Hugo Costa Paes, Octávio Luiz Franco
Antibiotics.2024; 13(11): 1042. CrossRef
Optimizing Treatment for Carbapenem-Resistant Acinetobacter baumannii Complex Infections: A Review of Current Evidence
Seong Jin Choi, Eu Suk Kim
Infection & Chemotherapy.2024; 56(2): 171. CrossRef
Advances in skin gene therapy: utilizing innovative dressing scaffolds for wound healing, a comprehensive review
Fatemeh Karimzadeh, Elahe Soltani Fard, Akram Nadi, Rahim Malekzadeh, Fatemeh Elahian, Seyed Abbas Mirzaei
Journal of Materials Chemistry B.2024; 12(25): 6033. CrossRef
Colistin Resistance Mechanism and Management Strategies of Colistin-Resistant Acinetobacter baumannii Infections
Md Minarul Islam, Da Eun Jung, Woo Shik Shin, Man Hwan Oh
Pathogens.2024; 13(12): 1049. CrossRef
Progress in Programmable DNA-Aided Self-Assembly of the Master Frame of a Drug Delivery System
Gary Q. Yang, Weibin Cai, Zhiwen Zhang, Yujun Wang
ACS Applied Bio Materials.2023; 6(12): 5125. CrossRef
Neglected Zoonotic Diseases: Advances in the Development of Cell-Penetrating and Antimicrobial Peptides against Leishmaniosis and Chagas Disease
Sara M. Robledo, Silvia Pérez-Silanes, Celia Fernández-Rubio, Ana Poveda, Lianet Monzote, Víctor M. González, Paloma Alonso-Collado, Javier Carrión
Pathogens.2023; 12(7): 939. CrossRef
Applications and Challenges of Bacteriostatic Aptamers in the Treatment of Common Pathogenic Bacteria Infections
Diandian Li, Yuan Su, Jie Li, Rong Liu, Bing Fang, Jingjing He, Wentao Xu, Longjiao Zhu
Biomacromolecules.2023; 24(11): 4568. CrossRef
Promising Acinetobacter baumannii Vaccine Candidates and Drug Targets in Recent Years
Yong Chiang Tan, Chandrajit Lahiri
Frontiers in Immunology.2022;[Epub] CrossRef
Advances and Perspective on Antimicrobial Nanomaterials for Biomedical Applications
Preeti Garg, Prerna Attri, Rohit Sharma, Moondeep Chauhan, Ganga Ram Chaudhary
Frontiers in Nanotechnology.2022;[Epub] CrossRef
Aptamer Decorated Emodin Nanoparticles-Assisted Delivery of Dermcidin-Derived Peptide DCD-1L: Photoactive Bio-Theragnostic Agent for Enterococcus Faecalis Biofilm Destruction
Maryam Pourhajibagher, Abbas Bahador
SSRN Electronic Journal .2022;[Epub] CrossRef
Development of DNA aptamers specific for small therapeutic peptides using a modified SELEX method
Jaemin Lee, Minkyung Ryu, Dayeong Bae, Hong-Man Kim, Seong-il Eyun, Jeehyeon Bae, Kangseok Lee
Journal of Microbiology.2022; 60(7): 659. CrossRef
Aptamer decorated emodin nanoparticles-assisted delivery of dermcidin-derived peptide DCD-1L: Photoactive bio-theragnostic agent for Enterococcus faecalis biofilm destruction
Maryam Pourhajibagher, Abbas Bahador
Photodiagnosis and Photodynamic Therapy.2022; 39: 103020. CrossRef

Brevibacillus antibioticus sp. nov., with a broad range of antibacterial activity, isolated from soil in the Nakdong River: Ahyoung Choi , Young Ho Nam , Kiwoon Baek , Eu Jin Chung; J. Microbiol. 2019;57(11):991-996. Published online October 28, 2019; DOI: https://doi.org/10.1007/s12275-019-9325-y

47 View
0 Download
2 Web of Science
2 Crossref

Abstract

A Gram-stain-positive, aerobic, motile, and rod-shaped bacterial strain designated TGS2-1T was isolated from sediment soil in the Nakdong River, Republic of Korea. The optimal growth of strain TGS2-1T was observed at 28°C and pH 7.0 without NaCl supplementation. Strain TGS2-1T revealed antibiosis against various bacteria, including Staphylococcus aureus KCCM 4051, CCARM 3089 (methicillin resistant strains), Enterococcus faecalis KCCM 11814, Escherichia coli KCTC 2443, Candida albicans KACC 7270, and Filobasidium neoformans KCTC 7902. Phylogenetic analyses based on the 16S rRNA gene sequences indicated that strain TGS2-1T belonged to the genus Brevibacillus and shared 93.8–99.7% sequence similarity with Brevibacillus species. Whole-genome sequencing of strain TGS2-1T revealed a genome size of 6.2 Mbp and DNA G + C content of 47.0 mol%. The TGS2-1T genome shared an average nucleotide identity and digital DNA-DNA hybridization of 74.6–93.3% and 18.6–67.1%, respectively, with six related Brevibacillus genomes. The major fatty acid constituents of strain TGS2-1T were anteiso-C15:0 (62.3%) and anteiso-C17:0 (10.8%). Cells of strain TGS2-1T contained diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, seven unidentified aminophospholipids, and five unidentified lipids. The isoprenoid quinone detected in the strain was menaquinone-7 (MK-7). Based on data obtained from this polyphasic taxonomic study, strain TGS2-1T represents a novel species belonging to genus Brevibacillus, for which the name B. antibioticus sp. nov. is proposed. The type strain is TGS2-1T (= KCCM 90326T = NBRC 113840T = FBCC-B2501).

Citations

Citations to this article as recorded by

Traditional processing increases biological activities of Dendrobium offificinale Kimura et. Migo in Southeast Yunnan, China
Di Zhou, Ying Zhao, Zhilin Chen, Xiuxiang Yan, Yanqiang Zhao, Lu Gao, Lixin Yang
Scientific Reports.2022;[Epub] CrossRef
Marine Bacterial Secondary Metabolites: A Treasure House for Structurally Unique and Effective Antimicrobial Compounds
Ramanathan Srinivasan, Arunachalam Kannappan, Chunlei Shi, Xiangmin Lin
Marine Drugs.2021; 19(10): 530. CrossRef

The antibacterial activity of E. coli bacteriophage lysin lysep3 is enhanced by fusing the Bacillus amyloliquefaciens bacteriophage endolysin binding domain D8 to the C-terminal region: Shuang Wang , Jingmin Gu , Meng Lv , Zhimin Guo , Guangmou Yan , Ling Yu , Chongtao Du , Xin Feng , Wenyu Han , Changjiang Sun , Liancheng Lei; J. Microbiol. 2017;55(5):403-408. Published online January 26, 2017; DOI: https://doi.org/10.1007/s12275-017-6431-6

52 View
0 Download
31 Crossref

Abstract

Bacteriophage endolysin is one of the most promising anti-biotic substitutes, but in Gram-negative bacteria, the outer membrane prevents the lysin from hydrolyzing peptidogly-cans and blocks the development of lysin applications. The prime strategy for new antibiotic substitutes is allowing lysin to access the peptidoglycan from outside of the bacteria by reformation of the lysin. In this study, the novel Escherichia coli (E. coli) phage lyase lysep3, which lacks outside-in cata-lytic ability, was fused with the N-terminal region of the Bacillus amyloliquefaciens lysin including its cell wall bind-ing domain D8 through the best manner of protein fusion based on the predicted tertiary structure of lysep3-D8 to ob-tain an engineered lysin that can lyse bacteria from the out-side. Our results showed that lysep3-D8 could lyse both Gram- negative and Gram-positive bacteria, whereas lysep3 and D8 have no impact on bacterial growth. The MIC of lysep3-D8 on E. coli CVCC1418 is 60 μg/ml; lysep3-D8 can inhibit the growth of bacteria up to 12 h at this concentration. The bac-tericidal spectrum of lysep3-D8 is broad, as it can lyse of all of 14 E. coli strains, 3 P. aeruginosa strains, 1 Acinetobacter baumannii strain, and 1 Streptococcus strain. Lysep3-D8 has sufficient bactericidal effects on the 14 E. coli strains tested at the concentration of 100 μg/ml. The cell wall binding do-main of the engineered lysin can destroy the integrity of the outer membrane of bacteria, thus allowing the catalytic do-main to reach its target, peptidoglycan, to lyse the bacteria. Lysep3-D8 can be used as a preservative in fodder to benefit the health of animals. The method we used here proved to be a successful exploration of the reformation of phage lysin.

Citations

Citations to this article as recorded by

Engineering strategies and challenges of endolysin as an antibacterial agent against Gram‐negative bacteria
Tianyu Zheng, Can Zhang
Microbial Biotechnology.2024;[Epub] CrossRef
Role of hypothetical protein PA1-LRP in antibacterial activity of endolysin from a new Pantoea phage PA1
Ye Tian, Xinyan Xu, Munazza Ijaz, Ying Shen, Muhammad Shafiq Shahid, Temoor Ahmed, Hayssam M. Ali, Chengqi Yan, Chunyan Gu, Jianfei Lu, Yanli Wang, Gabrijel Ondrasek, Bin Li
Frontiers in Microbiology.2024;[Epub] CrossRef
New-Generation Antibacterial Agent—Cellulose-Binding Thermostable TP84_Endolysin
Małgorzata Ponikowska, Joanna Żebrowska, Piotr M. Skowron
International Journal of Molecular Sciences.2024; 25(23): 13111. CrossRef
Characterization of Pseudomonas aeruginosa bacteriophages and control hemorrhagic pneumonia on a mice model
Yanjie Zhang, Ruiqing Wang, Qingxia Hu, Ni Lv, Likun Zhang, Zengqi Yang, Yefei Zhou, Xinglong Wang
Frontiers in Microbiology.2024;[Epub] CrossRef
Advances in the development of phage-mediated cyanobacterial cell lysis
Haojie Jin, Wanzhao Ge, Mengzhe Li, Yan Wang, Yanjing Jiang, Jiaqi Zhang, Yike Jing, Yigang Tong, Yujie Fu
Critical Reviews in Biotechnology.2024; : 1. CrossRef
Biological and genomic characterization of a polyvalent phage PSH-1 against multidrug-resistant Salmonella Enteritidis
Shuai-Hua Li, Rui-Yun Wang, Jun-Kai Zhang, Kai-Fang Yi, Jian-Hua Liu, Hua Wu, Li Yuan, Ya-Jun Zhai, Gong-Zheng Hu
BMC Microbiology.2024;[Epub] CrossRef
Beyond antibiotics: phage-encoded lysins against Gram-negative pathogens
Sanket Shah, Ritam Das, Bhakti Chavan, Urmi Bajpai, Sarmad Hanif, Syed Ahmed
Frontiers in Microbiology.2023;[Epub] CrossRef
The Broad-Spectrum Endolysin LySP2 Improves Chick Survival after Salmonella Pullorum Infection
Hewen Deng, Mengjiao Li, Qiuyang Zhang, Chencheng Gao, Zhanyun Song, Chunhua Chen, Zhuo Wang, Xin Feng
Viruses.2023; 15(4): 836. CrossRef
Development of a Magnetic Bead-Based Method for Specific Detection of Enterococcus faecalis Using C-Terminal Domain of ECP3 Phage Endolysin
Yoon-Jung Choi, Shukho Kim, Jungmin Kim
Journal of Microbiology and Biotechnology.2023; 33(7): 964. CrossRef
Identification of Three Campylobacter Lysins and Enhancement of Their Anti-Escherichia coli Efficacy Using Colicin-Based Translocation and Receptor-Binding Domain Fusion
Peiqi Liu, Xinying Dong, Xuewei Cao, Qianmei Xie, Xiuqin Huang, Jinfei Jiang, Huilin Dai, Zheng Tang, Yizhen Lin, Saixiang Feng, Kaijian Luo, Jasna Kovac
Microbiology Spectrum.2023;[Epub] CrossRef
Isolation of Klebsiella pneumoniae Phage vB_KpnS_MK54 and Pathological Assessment of Endolysin in the Treatment of Pneumonia Mice Model
Biao Lu, Xueping Yao, Guangli Han, Zidan Luo, Jieru Zhang, Kang Yong, Yin Wang, Yan Luo, Zexiao Yang, Meishen Ren, Suizhong Cao
Frontiers in Microbiology.2022;[Epub] CrossRef
How Good are Bacteriophages as an Alternative Therapy to Mitigate Biofilms of Nosocomial Infections
Aditi Singh, Sudhakar Padmesh, Manish Dwivedi, Irena Kostova
Infection and Drug Resistance.2022; Volume 15: 503. CrossRef
Complete genome sequencing of a Tequintavirus bacteriophage with a broad host range against Salmonella Abortus equi isolates from donkeys
Wenhua Liu, Letian Han, Peng Song, Huzhi Sun, Can Zhang, Ling Zou, Jiaqi Cui, Qiang Pan, Huiying Ren
Frontiers in Microbiology.2022;[Epub] CrossRef
Characterization of Salmonella endolysin XFII produced by recombinant Escherichia coli and its application combined with chitosan in lysing Gram-negative bacteria
Shuhang Zhang, Yan Chang, Qing Zhang, Yingbo Yuan, Qingsheng Qi, Xuemei Lu
Microbial Cell Factories.2022;[Epub] CrossRef
The endolysin of the Acinetobacter baumannii phage vB_AbaP_D2 shows broad antibacterial activity
Yuyu Yuan, Xiaoyu Li, Lili Wang, Gen Li, Cong Cong, Ruihua Li, Huijing Cui, Bilal Murtaza, Yongping Xu
Microbial Biotechnology.2021; 14(2): 403. CrossRef
Lysins breaking down the walls of Gram-negative bacteria, no longer a no-go
Diana Gutiérrez, Yves Briers
Current Opinion in Biotechnology.2021; 68: 15. CrossRef
The Advantages and Challenges of Using Endolysins in a Clinical Setting
Ellen Murray, Lorraine A. Draper, R. Paul Ross, Colin Hill
Viruses.2021; 13(4): 680. CrossRef
The strategy of biopreservation of meat product against MRSA using lytic domain of lysin from Staphylococcus aureus bacteriophage
Jiai Yan, Ruijin Yang, Shuhuai Yu, Wei Zhao
Food Bioscience.2021; 41: 100967. CrossRef
Phage vB_PaeS-PAJD-1 Rescues Murine Mastitis Infected With Multidrug-Resistant Pseudomonas aeruginosa
Zhaofei Wang, Yibing Xue, Ya Gao, Mengting Guo, Yuanping Liu, Xinwei Zou, Yuqiang Cheng, Jingjiao Ma, Hengan Wang, Jianhe Sun, Yaxian Yan
Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef
Opportunities for broadening the application of cell wall lytic enzymes
Amala Bhagwat, Monica Mixon, Cynthia H. Collins, Jonathan S. Dordick
Applied Microbiology and Biotechnology.2020; 104(21): 9019. CrossRef
Gram-Negative Bacterial Lysins
Chandrabali Ghose, Chad W. Euler
Antibiotics.2020; 9(2): 74. CrossRef
Bacteriophage-derived endolysins to target gram-negative bacteria
Wing Ching Bianca Lai, Xi Chen, Marco Kai Yuen Ho, Jiang Xia, Sharon Shui Yee Leung
International Journal of Pharmaceutics.2020; 589: 119833. CrossRef
Bacteriophages and Lysins as Possible Alternatives to Treat Antibiotic-Resistant Urinary Tract Infections
Trinidad de Miguel, José Luis R. Rama, Carmen Sieiro, Sandra Sánchez, Tomas G. Villa
Antibiotics.2020; 9(8): 466. CrossRef
Managing urinary tract infections through phage therapy: a novel approach
Shikha Malik, Parveen Kaur Sidhu, J.S. Rana, Kiran Nehra
Folia Microbiologica.2020; 65(2): 217. CrossRef
Endolysins as emerging alternative therapeutic agents to counter drug-resistant infections
Vijay Singh Gondil, Kusum Harjai, Sanjay Chhibber
International Journal of Antimicrobial Agents.2020; 55(2): 105844. CrossRef
External lysis of Escherichia coli by a bacteriophage endolysin modified with hydrophobic amino acids
Guangmou Yan, Rui Yang, Kejia Fan, Hanlin Dong, Chencheng Gao, Shuang Wang, Ling Yu, Zhe Cheng, Liancheng Lei
AMB Express.2019;[Epub] CrossRef
Phage Lysins for Fighting Bacterial Respiratory Infections: A New Generation of Antimicrobials
Roberto Vázquez, Ernesto García, Pedro García
Frontiers in Immunology.2018;[Epub] CrossRef
Synthetic biology of modular endolysins
Hans Gerstmans, Bjorn Criel, Yves Briers
Biotechnology Advances.2018; 36(3): 624. CrossRef
Isolation and identification of Salmonella pullorum bacteriophage YSP2 and its use as a therapy for chicken diarrhea
Kunyuan Tie, Yuyu Yuan, Shiqing Yan, Xi Yu, Qiuyang Zhang, Huihui Xu, Yang Zhang, Jingmin Gu, Changjiang Sun, Liancheng Lei, Wenyu Han, Xin Feng
Virus Genes.2018; 54(3): 446. CrossRef
Engineering of Phage-Derived Lytic Enzymes: Improving Their Potential as Antimicrobials
Carlos São-José
Antibiotics.2018; 7(2): 29. CrossRef
Expression of a Peptidoglycan Hydrolase from Lytic Bacteriophages Atu_ph02 and Atu_ph03 Triggers Lysis of Agrobacterium tumefaciens
Hedieh Attai, Jeanette Rimbey, George P. Smith, Pamela J. B. Brown, M. Julia Pettinari
Applied and Environmental Microbiology.2017;[Epub] CrossRef

Research Support, Non-U.S. Gov'ts

Antimicrobial Effects of Herbal Extracts on Streptococcus mutans and Normal Oral Streptococci: Sung-Hoon Lee; J. Microbiol. 2013;51(4):484-489. Published online August 30, 2013; DOI: https://doi.org/10.1007/s12275-013-3312-5

38 View
0 Download
18 Scopus

Abstract: Streptococcus mutans is associated with dental caries. A cariogenic biofilm, in particular, has been studied extensively for its role in the formation of dental caries. Herbal extracts such as Cudrania tricuspidata, Sophora flavescens, Ginkgo biloba, and Betula Schmidtii have been used as a folk remedy for treating diseases. The purpose of this study was to evaluate and compare the antibacterial activity of herbal extracts against normal oral streptococci, planktonic and biofilm of S. mutans. Streptococcus gordonii, Streptococcus oralis, Streptococcus salivarius, Streptococcus sanguinis, and S. mutans were cultivated with brain heart infusion broth and susceptibility assay for the herbal extracts was performed according to the protocol of Clinical and Laboratory Standard Institute. Also, S. mutans biofilm was formed on a polystyrene 12-well plate and 8-well chamber glass slip using BHI broth containing 2% sucrose and 1% mannose after conditioning the plate and the glass slip with unstimulated saliva. The biofilm was treated with the herbal extracts in various concentrations and inoculated on Mitis-Salivarius bacitracin agar plate for enumeration of viable S. mutans by counting colony forming units. Planktonic S. mutans showed susceptibility to all of the extracts and S. mutans biofilm exhibited the highest level of sensitivity for the extracts of S. flavescens. The normal oral streptococci exhibited a weak susceptibility in comparison to S. mutans. S. oralis, however, was resistant to all of the extracts. In conclusion, the extract of S. flavescens may be a potential candidate for prevention and management of dental caries.

Copper as an Antimicrobial Agent against Opportunistic Pathogenic and Multidrug Resistant Enterobacter Bacteria: Wen-Xiao Tian , Shi Yu , Muhammad Ibrahim , Abdul Wareth Almonaofy , Liu He , Qiu Hui , Zhu Bo , Bin Li , Guan-lin Xie; J. Microbiol. 2012;50(4):586-593. Published online July 21, 2012; DOI: https://doi.org/10.1007/s12275-012-2067-8

39 View
0 Download
44 Scopus

Abstract: Infections by Enterobacter species are common and are multidrug resistant. The use of bactericidal surface materials such as copper has lately gained attention as an effective antimicrobial agent due to its deadly effects on bacteria, yeast, and viruses. The aim of the current study was to assess the antibacterial activity of copper surfaces against Enterobacter species. The antibacterial activity of copper surfaces was tested by overlying 5×106 CFU/ml suspensions of representative Enterobacter strains and comparing bacterial survival counts on copper surfaces at room temperature. Iron, stainless steel, and polyvinylchloride (PVC) were used as controls. The mechanisms responsible for bacterial killing on copper surfaces were investigated by a mutagenicity assay of the D-cycloserin (cyclA gene), single cell gel electrophoresis, a staining technique, and inductively coupled plasma mass spectroscopy. Copper yielded a significant decrease in the viable bacterial counts at 2 h exposure and a highly significant decrease at 4 h. Loss of cell integrity and a significantly higher influx of copper into bacterial cells exposed to copper surfaces, as compared to those exposed to the controls, were documented. There was no increase in mutation rate and DNA damage indicating that copper contributes to bacterial killing by adversely affecting cellular structure without directly targeting the genomic DNA. These findings suggest that copper’s antibacterial activity against Enterobacter species could be utilized in health care facilities and in food processing plants to reduce the bioburden, which would increase protection for susceptible members of the community.

NOTE] Antibiotic Resistance and Probiotic Properties of Dominant Lactic Microflora from Tungrymbai, an Ethnic Fermented Soybean Food of India: Sharmila Thokchom , Santa Ram Joshi; J. Microbiol. 2012;50(3):535-539. Published online June 30, 2012; DOI: https://doi.org/10.1007/s12275-012-1409-x

27 View
0 Download
15 Scopus

Abstract: The present investigation was conducted to assess lactic acid bacteria present in traditionally fermented food of ethnic tribes in India for probiotic properties, antibacterial activity, and antibiotic tolerance behavior. Enterococcus sp., Lactobacillus sp., and Lactococcus sp. showed antibacterial activity against Bacillus cereus MTCC 430, Staphylococcus aureus subsp. aureus MTCC 740, and Salmonella enterica ser. paratyphi A MTCC 735. Lactococcus sp. and Lactobacillus sp. could tolerate acidic conditions (pH 2) and high bile salt concentration (4000 ppm). The lactic microflora were found to be sensitive to most common antibiotics, except for cloxacillin (5 μg), cephalexin (30 μg), and cephalothin (30 μg).

Journal Article

Assessment of Resistomycin, as an Anticancer Compound Isolated and Characterized from Streptomyces aurantiacus AAA5: Rajendran Vijayabharathi , Per Bruheim , Trygve Andreassen , Duraisamy Senthil Raja , Palanisamy Bruntha Devi , Sathyaseelan Sathyabama , Venkatesan Brindha Priyadarisini; J. Microbiol. 2011;49(6):920-926. Published online December 28, 2011; DOI: https://doi.org/10.1007/s12275-011-1260-5

51 View
0 Download
34 Crossref

Abstract

A new actinomycete strain, isolated from humus soils in the Western Ghats, was found to be an efficient pigment producer. The strain, designated AAA5, was identified as a putative Streptomyces aurantiacus strain based on cultural properties, morphology, carbon source utilization, and analysis of the 16S rRNA gene. The strain produced a reddish-brown pigmented compound during the secondary metabolites phase. A yellow compound was derived from the extracted pigment and was identified as the quinone-related antibiotic resistomycin based on ultraviolet–visible spectrophotometry, fourier transform infrared spectroscopy, liquid chromatography and mass spectroscopy, and nuclear magnetic resonance analyses. The AAA5 strain was found to produce large quantities of resistomycin (52.5 mg/L). It showed potent cytotoxic activity against cell lines viz. HepG2 (hepatic carcinoma) and HeLa (cervical carcinoma) in vitro, with growth inhibition (GI50) of 0.006 and 0.005 μg/ml, respectively. The strain also exhibited broad antimicrobial activities against both Gram-positive and Gram-negative bacteria. Therefore, AAA5 may have great potential as an industrial resistomycin-producing strain.

Citations

Citations to this article as recorded by

Streptomyces tagetis sp. nov., a chromomycin producing bacteria isolated from the roots of Tagetes patula
Geeta Chhetri, Myeong Ji Kim, Inhyup Kim, Duc V. H. Tran, Young-Woo Kim, Hyun Woo Kim, Taegun Seo
Frontiers in Microbiology.2024;[Epub] CrossRef
Physico-chemical properties of Priestia endophytica UCM B-5715 fluorescent pigments
М. Kharkhota, М. Kharchuk, А. Kharchuk, G. Grabova, Yu Noskov, R. Linnik, А. Makeiev, L. Avdieieva
Biochemical and Biophysical Research Communications.2024; 741: 151040. CrossRef
Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells
Atikul Islam, Yu-Chun Chang, Xiao-Chi Chen, Chia-Wei Weng, Chien-Yu Chen, Che-Wei Wang, Mu-Kuan Chen, Alexander S Tikhomirov, Andrey E Shchekotikhin, Pin Ju Chueh
eLife.2024;[Epub] CrossRef
Streptomyces Paradigm in Anticancer Therapy: A State-of-the Art Review
Yashendra Sethi, Vidhi Vora, Onyekachi Emmanuel Anyagwa, Nafisa Turabi, Maya Abdelwahab, Oroshay Kaiwan, Hitesh Chopra, Mohamed Shah Attia, Galal Yahya, Talha Bin Emran, Inderbir Padda
Current Cancer Therapy Reviews.2024; 20(4): 386. CrossRef
Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents
Eileena F. Giurini, Aishvarya Godla, Kajal H. Gupta
Cancer Gene Therapy.2024; 31(2): 187. CrossRef
Exploration of the Bioactivity of Pigmented Extracts from Streptomyces Strains Isolated Along the Banks of the Guaviare and Arauca Rivers (Colombia)
Aixa A. Sarmiento-Tovar, Sara J. Prada-Rubio, Juliana Gonzalez-Ronseria, Ericsson Coy-Barrera, Luis Diaz
Fermentation.2024; 10(10): 529. CrossRef
Discovery of two new actinobacteria, Micromonospora palythoicola sp. nov. and Streptomyces poriticola sp. nov., isolated from marine invertebrates
Pawina Kanchanasin, Thanarat Salahong, Paranee Sripreechasak, Chanwit Suriyachadkun, Enjuro Harunari, Yasuhiro Igarashi, Somboon Tanasupawat, Supannikar Tawinwung, Sornkanok Vimolmangkang, Chatchai Chaotham, Wongsakorn Phongsopitanun
Scientific Reports.2024;[Epub] CrossRef
Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells
Atikul Islam, Yu-Chun Chang, Xiao-Chi Chen, Chia-Wei Weng, Chien-Yu Chen, Che-Wei Wang, Mu-Kuan Chen, Alexander S Tikhomirov, Andrey E Shchekotikhin, Pin Ju Chueh
eLife.2024;[Epub] CrossRef
Resistomycin Suppresses Prostate Cancer Cell Growth by Instigating Oxidative Stress, Mitochondrial Apoptosis, and Cell Cycle Arrest
Abeer S. Aloufi, Ola A. Habotta, Mohamed S. Abdelfattah, Marina N. Habib, Mohamed M. Omran, Sally A. Ali, Ahmed E. Abdel Moneim, Shereen M. Korany, Aisha M. Alrajhi
Molecules.2023; 28(23): 7871. CrossRef
Resistomycin Inhibits Wnt/β-Catenin Signaling to Induce the Apoptotic Death of Human Colorectal Cancer Cells
Yaoyao Zhu, E Zhang, Huan Gao, Chuangeng Shang, Mengxiong Yin, Mingtao Ma, Yu Liu, Xuanfeng Zhang, Xia Li
Marine Drugs.2023; 21(12): 622. CrossRef
Bioproduction and Characterization of Pigments from Streptomyces sp. Isolated from Marine Biotope
S. Nair, J. Abraham
Applied Biochemistry and Microbiology.2022; 58(6): 701. CrossRef
Exploring microbial bioactive molecules from Western Ghats, India
Zinal T. Vasava, Kruti J. Mistry, Pooja P. Patel, Anoop R. Markande
Acta Ecologica Sinica.2022; 42(6): 593. CrossRef
Streptomyces-Derived Bioactive Pigments: Ecofriendly Source of Bioactive Compounds
Aixa A. Sarmiento-Tovar, Laura Silva, Jeysson Sánchez-Suárez, Luis Diaz
Coatings.2022; 12(12): 1858. CrossRef
Fabrication and characterization of pigmented secondary metabolites bound liposomes with improved cytotoxic activity against prostate and hepatic cancer
Medhat W. Shafaa, Elsayed S. E. Hassan, Ahmed H. I. Faraag, Ehab Essawy, Mohamed S. Abdelfattah
International Nano Letters.2022; 12(4): 409. CrossRef
Chlororesistoflavins A and B, Chlorinated Benzopyrene Antibiotics Produced by the Marine-Derived Actinomycete Streptomyces sp. Strain EG32
Min Cheol Kim, Zhifei Li, Reiko Cullum, Tadeusz F. Molinski, Mennat Allah G. Eid, Ali M. S. Hebishy, Ahmed H. I. Faraag, Ahmed E. Abdel Moneim, Mohamed S. Abdelfattah, William Fenical
Journal of Natural Products.2022; 85(1): 270. CrossRef
Synergistic Effect of Biosynthesized Silver Nanoparticles and Natural Phenolic Compounds against Drug-Resistant Fish Pathogens and Their Cytotoxicity: An In Vitro Study
Ehab Essawy, Mohamed S. Abdelfattah, Mansour El-Matbouli, Mona Saleh
Marine Drugs.2021; 19(1): 22. CrossRef
Inhibitory and ameliorative effect of heliomycin derived from actinomycete on induced hepatocellular carcinoma in rats
Ahmed S. Alazzouni, Abdulla A. Mahmoud, Mohamed M. Omran, Ehab A. Essawy, Mohga S. Abdalla, Mohamed S. Abdelfattah
Naunyn-Schmiedeberg's Archives of Pharmacology.2021; 394(6): 1091. CrossRef
Water-Soluble Heliomycin Derivatives to Target i-Motif DNA
Alexander S. Tikhomirov, Mahmoud A. S. Abdelhamid, Georgy Y. Nadysev, George V. Zatonsky, Eugene E. Bykov, Pin Ju Chueh, Zoë A. E. Waller, Andrey E. Shchekotikhin
Journal of Natural Products.2021; 84(5): 1617. CrossRef
Resistomycin Induced Apoptosis and Cycle Arrest in Human Hepatocellular Carcinoma Cells by Activating p38 MAPK Pathway In Vitro and In Vivo
Zhuo Han, Xingming Zhao, E Zhang, Jiahui Ma, Hao Zhang, Jianjiang Li, Weidong Xie, Xia Li
Pharmaceuticals.2021; 14(10): 958. CrossRef
Marine Actinomycetes-Derived Secondary Metabolites Overcome TRAIL-Resistance via the Intrinsic Pathway through Downregulation of Survivin and XIAP
Mohammed I. Y. Elmallah, Sheron Cogo, Andrei A. Constantinescu, Selene Elifio-Esposito, Mohammed S. Abdelfattah, Olivier Micheau
Cells.2020; 9(8): 1760. CrossRef
Isolation of Resistomycin from a Terrestrial Actinomycete with TRAIL Resistance-overcoming Activity
Xuefeidan Liu, Midori A. Arai, Kazufumi Toume and Masami Ishibashi
Natural Product Communications.2018;[Epub] CrossRef
Heliomycin and tetracinomycin D: anthraquinone derivatives with histone deacetylase inhibitory activity from marine sponge-associated Streptomyces sp. SP9
Mohamed Saleh Abdelfattah, Mohammed Ismail Youssef Elmallah, Ahmed Hassan Ibrahim Faraag, Ali Mohamed Salah Hebishy, Neama Hassan Ali
3 Biotech.2018;[Epub] CrossRef
Profiling of red pigment produced by Streptomyces sp. JAR6 and its bioactivity
Jayanthi Abraham, Ritika Chauhan
3 Biotech.2018;[Epub] CrossRef
Streptomyces sp. strain SK68, isolated from peanut rhizosphere, promotes growth and alleviates salt stress in tomato (Solanum lycopersicum cv. Micro-Tom)
Karthiyaini Damodharan, Sasikumar Arunachalam Palaniyandi, Bao Le, Joo-Won Suh, Seung Hwan Yang
Journal of Microbiology.2018; 56(10): 753. CrossRef
A study of comparative modelling, simulation and molecular dynamics of CXCR3 receptor with lipid bilayer
Shanmugarajan Dhivya, Chinaga Suresh Kumar, Vijayakumar Bommuraj, Rethavathi Janarthanam, Meena Chandran, Talambedu Usha, Sushil Kumar Middha
Journal of Biomolecular Structure and Dynamics.2018; 36(9): 2361. CrossRef
Cytotoxicity of n-Butanol Extracts of Streptomyces Against Human Breast Cancer Cells
Maher Obeidat
International Journal of Pharmacology.2017; 13(8): 969. CrossRef
Streptomyces canalis sp. nov., an actinomycete isolated from an alkali-removing canal
Yu-Xuan Xie, Xiao-Xue Han, Xiao-Xia Luo, Zhan-Feng Xia, Chuan-Xing Wan, Li-Li Zhang
International Journal of Systematic and Evolutionary Microbiology.2016; 66(8): 3219. CrossRef
Optimization of an Anti Staphylococcus Antibiotic Produced by Tropical Soil Dwelling Streptomyces Parvulus
Sonashia Velho-Pereira
SSRN Electronic Journal.2016;[Epub] CrossRef
Using Molecular Networking for Microbial Secondary Metabolite Bioprospecting
Kevin Purves, Lynsey Macintyre, Debra Brennan, Guðmundur Hreggviðsson, Eva Kuttner, Margrét Ásgeirsdóttir, Louise Young, David Green, Ruangelie Edrada-Ebel, Katherine Duncan
Metabolites.2016; 6(1): 2. CrossRef
Antibacterial and anticancer activity of marineStreptomyces parvus: optimization and application
Hanan Abd-Elnaby, Gehan Abo-Elala, Usama Abdel-Raouf, Abeer Abd-elwahab, Moaz Hamed
Biotechnology & Biotechnological Equipment.2016; 30(1): 180. CrossRef
Antitumor compounds from Streptomyces sp. KML-2, isolated from Khewra salt mines, Pakistan
Usman Aftab, David L. Zechel, Imran Sajid
Biological Research.2015;[Epub] CrossRef
Phylum-Specific Regulation of Resistomycin Production in a Streptomyces sp. via Microbial Coculture
Skylar Carlson, Urszula Tanouye, Sesselja Omarsdottir, Brian T. Murphy
Journal of Natural Products.2015; 78(3): 381. CrossRef
Eliciting antibiotics active against the ESKAPE pathogens in a collection of actinomycetes isolated from mountain soils
Hua Zhu, Jasper Swierstra, Changsheng Wu, Geneviève Girard, Young Hae Choi, Willem van Wamel, Stephanie K. Sandiford, Gilles P. van Wezel
Microbiology.2014; 160(8): 1714. CrossRef
Actinomycetes from Western Ghats of Tamil Nadu with its antimicrobial properties
Arasu M Valan, S Ignacimuthu, P Agastian
Asian Pacific Journal of Tropical Biomedicine.2012; 2(2): S830. CrossRef

Research Support, Non-U.S. Gov'ts

Inhibitory Effect of the Essential Oil from Chamaecyparis obtusa on the Growth of Food-Borne Pathogens: Mi-Jin Park , Won-Sil Choi , Ha-Young Kang , Ki-Seob Gwak , Geun-Shik Lee , Eui-Bae Jeung , In-Gyu Choi; J. Microbiol. 2010;48(4):496-501. Published online August 20, 2010; DOI: https://doi.org/10.1007/s12275-010-9327-2

56 View
0 Download
16 Crossref

Abstract

In this study, the antibacterial activity of essential oil from Chamaecyparis obtusa (Sieb. et Zucc) leaves and twigs was investigated. The test strains were Klebsiella pneumoniae, Listeria monocytogenes, Salmonella typhimurium, Staphylococcus aureus, Escherichia coli, Legionella pneumophila, and Methicilline-resistant Staphylococcus aureus. Antibacterial activity was estimated by measuring bacterial growth inhibition. Histopathological examination was also performed. C. obtusa oil distinctly inhibited the growth of all test strains and exhibited the strongest antibacterial activity against L. monocytogenes. It was chromatographically divided into several fractions. The fractions were further tested against antibacterial activity and their chemical compositions were analyzed. The fraction containing terpinen-4-ol (TA) showed high antibacterial activity toward all strains tested. Tests with authentic samples showed that TA played a major role in the antibacterial activity of C. obtusa oil, and in a mice test, the oil actively minimized inflammation by S. aureus.

Citations

Citations to this article as recorded by

The Precious Potential of the Sacred Tree Chamaecyparis obtusa (Siebold & Zucc.) Endl. as a Source of Secondary Metabolites with Broad Biological Applications
Karol Maksymilian Górski, Tomasz Kowalczyk, Laurent Picot, Patricia Rijo, Mansour Ghorbanpour, Przemysław Sitarek
International Journal of Molecular Sciences.2024; 25(5): 2723. CrossRef
Phytochemical-Based Nanoantioxidants Stabilized with Polyvinylpyrrolidone for Enhanced Antibacterial, Antioxidant, and Anti-Inflammatory Activities
Hyeryeon Oh, Jin Sil Lee, Hyojung Park, Panmo Son, Byoung Seung Jeon, Sang Soo Lee, Daekyung Sung, Jong-Min Lim, Won Il Choi
Antioxidants.2024; 13(9): 1056. CrossRef
Cell Extracts Derived from Cypress and Cedar Show Antiviral Activity against Enveloped Viruses
Takashi Furukawa, Ayumu Inagaki, Takeshi Hatta, Suzuha Moroishi, Katsuki Kawanishi, Yuki Itoh, Shotaro Maehana, Mohan Amarasiri, Kazunari Sei
Microorganisms.2024; 12(9): 1813. CrossRef
Antibacterial and virucidal activity of 28 extracts from plants endemic to Korea against Bacillus cereus, Staphylococcus aureus, and murine norovirus
Hyun-Joo Chang, Ji Hye Han, Nari Lee, Sung-Wook Choi
Journal of Applied Biological Chemistry.2023;[Epub] CrossRef
Preparation of Green Anti-Staphylococcus aureus Inclusion Complexes Containing Hinoki Essential Oil
Peifu Kong, Kotchaporn Thangunpai, Ainun Zulfikar, Shunsuke Masuo, Junichi Peter Abe, Toshiharu Enomae
Foods.2023; 12(16): 3104. CrossRef
Terpinen-4-ol, the Main Bioactive Component of Tea Tree Oil, as an Innovative Antimicrobial Agent against Legionella pneumophila
Francesca Mondello, Stefano Fontana, Maria Scaturro, Antonietta Girolamo, Marisa Colone, Annarita Stringaro, Maura Di Vito, Maria Luisa Ricci
Pathogens.2022; 11(6): 682. CrossRef
Impact of Hinoki Cypress Wood on Diversity of Microflora: A Case Study from Owase City Hall
Daisuke Tanaka, Daisuke Uei, Jun Matsui, Masahiro Matsunaga, Masaaki Morimoto, Fumito Maruyama
Diversity.2021; 13(10): 473. CrossRef
Potential Role of Plant Extracts and Phytochemicals Against Foodborne Pathogens
Farhat Ullah, Muhammad Ayaz, Abdul Sadiq, Farman Ullah, Ishtiaq Hussain, Muhammad Shahid, Zhanibek Yessimbekov, Anjana Adhikari-Devkota, Hari Prasad Devkota
Applied Sciences.2020; 10(13): 4597. CrossRef
In Vivo and In Vitro Study on the Efficacy of Terpinen-4-ol in Dextran Sulfate Sodium-Induced Mice Experimental Colitis
Zecai Zhang, Peng Shen, Xiaojie Lu, Yanxin Li, Jiuxi Liu, Bo Liu, Yunhe Fu, Yongguo Cao, Naisheng Zhang
Frontiers in Immunology.2017;[Epub] CrossRef
In Vivo Study of the Efficacy of the Essential Oil of Zanthoxylum bungeanum Pericarp in Dextran Sulfate Sodium-Induced Murine Experimental Colitis
Zecai Zhang, Peng Shen, Jiuxi Liu, Cong Gu, Xiaojie Lu, Yanxin Li, Yongguo Cao, Bo Liu, Yunhe Fu, Naisheng Zhang
Journal of Agricultural and Food Chemistry.2017; 65(16): 3311. CrossRef
Inhibition of litter decomposition of two emergent macrophytes by addition of aromatic plant powder
Ya-jun Xie, Yong-hong Xie, Hua-yun Xiao, Zheng-miao Deng, Ying Pan, Bai-han Pan, Jia-yu Hu
Scientific Reports.2017;[Epub] CrossRef
Activity of Six Essential Oils Extracted from Tunisian Plants against Legionella pneumophila
Naouel Chaftar, Marion Girardot, Nathalie Quellard, Jérôme Labanowski, Tawfik Ghrairi, Khaled Hani, Jacques Frère, Christine Imbert
Chemistry & Biodiversity.2015; 12(10): 1565. CrossRef
Physiological effect of olfactory stimulation by Hinoki cypress (Chamaecyparis obtusa) leaf oil
Harumi Ikei, Chorong Song, Yoshifumi Miyazaki
Journal of Physiological Anthropology.2015;[Epub] CrossRef
Melaleuca alternifolia Concentrate Inhibits in Vitro Entry of Influenza Virus into Host Cells
Xinghua Li, Songwei Duan, Cordia Chu, Jun Xu, Gucheng Zeng, Alfred Lam, Junmei Zhou, Yue Yin, Danyun Fang, Maxwell Reynolds, Huaiyu Gu, Lifang Jiang
Molecules.2013; 18(8): 9550. CrossRef
Antifungal and Antibacterial Activity of the Essential Oil of Chamaecyparis Lawsoniana from Spain
Jesús Palá-Paúl, Jaime Usano-Alemany, Elena Granda, Ana-Cristina Soria
Natural Product Communications.2012;[Epub] CrossRef
Antimicrobial Effect of Various Chopping Boards against Food-borne Bacteria
Ji-Young Kim, Hyoung-Jae Lee, Jeong-Yong Cho, Hyun-Cheol Lim, Gyeong-Cheol Choi, Du-Woon Kim, Keun-Hyung Park, Jae-Hak Moon
Korean Journal of Food Science and Technology.2012; 44(1): 114. CrossRef

Note] Antibacterial Activity of Recombinant hCAP18/LL37 Protein Secreted from Pichia pastoris: Soon-ja Kim , Renshu Quan , Sung-Jin Lee , Hak-Kyo Lee , Joong-Kook Choi; J. Microbiol. 2009;47(3):358-362. Published online June 26, 2009; DOI: https://doi.org/10.1007/s12275-009-0131-9

30 View
0 Download
17 Scopus

Abstract: Human antimicrobial peptide CAP18/LL37 (hCAP18/LL37) was expressed in Pichia pastoris and its antibacterial activity was tested against pathogenic bacteria. The full length ORF of hCAP18/LL37 was cloned into the pPICZαA vector followed by integration into the genomic AOX1 gene of P. pastoris. Agar diffusion assay demonstrated that the different hCAP18/LL37 transformants showed various antibacterial activities against Staphylococcus aureus, Micrococcus luteus, and Salmonella gastroenteritis. The secreted form of hCAP18/LL37 exhibited its maximum activity after 72 h incubation with 2% methanol in MM media, not in BMM. This result suggests that the yeast secreted expression system can be used as a production tool of antimicrobial peptides for industrial or pharmaceutical application.

Journal Article

Inhibitory Effect of Methyl Gallate and Gallic Acid on Oral Bacteria: Mi-Sun Kang , Jong-Suk Oh , In-Chol Kang , Suk-Jin Hong , Choong-Ho Choi; J. Microbiol. 2008;46(6):744-750. Published online December 24, 2008; DOI: https://doi.org/10.1007/s12275-008-0235-7

38 View
0 Download
204 Crossref

Abstract

This study examined the ability of methyl gallate (MG) and gallic acid (GA), the main compounds of gallotannins in Galla Rhois, to inhibit the proliferation of oral bacterial and the in vitro formation of Streptococcus mutans biofilms. The antimicrobial activities of these compounds were evaluated in vitro using the broth microdilution method and a beaker-wire test. Both MG and GA had inhibitory effects on the growth of cariogenic (MIC<8 mg/ml) and periodontopathic bacteria (MIC=1 mg/ml). Moreover, these compounds significantly inhibited the in vitro formation of S. mutans biofilms (MG, 1 mg/ml; GA, 4 mg/ml; P<0.05). MG was more effective in inhibiting bacterial growth and the formation of S. mutans biofilm than GA. In conclusion, MG and GA can inhibit the growth of oral pathogens and S. mutans biofilm formation, and may be used to prevent the formation of oral biofilms.

Citations

Citations to this article as recorded by

Antibacterial activity of gallic acid and methyl gallate against emerging non-fermenting bacilli
Orlando Flores-Maldonado, Jorge Dávila-Aviña, Gloria M. González, Miguel A. Becerril-García, Ana L. Ríos-López
Folia Microbiologica.2025; 70(1): 127. CrossRef
Bioactive compounds from Actinidia arguta fruit as a new strategy to fight glioblastoma
Catarina Macedo, Paulo C. Costa, Francisca Rodrigues
Food Research International.2024; 175: 113770. CrossRef
Antibacterial efficacy of copper-based metal–organic frameworks against Escherichia coli and Lactobacillus
Sandy Elmehrath, Khansa Ahsan, Nayla Munawar, Ahmed Alzamly, Ha L. Nguyen, Yaser Greish
RSC Advances.2024; 14(22): 15821. CrossRef
Potential therapeutic agents of Bombyx mori silk cocoon extracts from agricultural product for inhibition of skin pathogenic bacteria and free radicals
Thida Kaewkod, Puangphaka Kumseewai, Sureeporn Suriyaprom, Varachaya Intachaisri, Nitsanat Cheepchirasuk, Yingmanee Tragoolpua
PeerJ.2024; 12: e17490. CrossRef
Gallic acid: design of a pyrogallol-containing hydrogel and its biomedical applications
Wu Weian, Ye Yunxin, Wang Ziyan, Jiang Qianzhou, Guo Lvhua
Biomaterials Science.2024; 12(6): 1405. CrossRef
Methyl gallate attenuates virulence and decreases antibiotic resistance in extensively drug-resistant Pseudomonas aeruginosa
Orlando Flores-Maldonado, Cristina I. Lezcano-Domínguez, Jorge Dávila-Aviña, Gloria M. González, Ana L. Ríos-López
Microbial Pathogenesis.2024; 194: 106830. CrossRef
Antimicrobial Effect of Lippia citriodora Extract in Combination with Gallic Acid or Octyl Gallate on Bacteria from Meat
Javier Rúa, Javier Sanz-Gómez, Sheila Maestro, Irma Caro, María Rosario García-Armesto
Foods.2024; 13(11): 1643. CrossRef
Methyl gallate isolated from partridge tea (Mallotus oblongifolius (Miq.) Müll.Arg.) inhibits the biofilms and virulence factors of Burkholderia thailandensis
Kai-Zhong Xu, Shi-Liang Xiang, Ying-Jie Wang, Bo Wang, Ai-Qun Jia
Journal of Ethnopharmacology.2024; 320: 117422. CrossRef
Ameliorating impaired cardiac function in myocardial infarction using exosome-loaded gallic-acid-containing polyurethane scaffolds
Ankita Das, Aman Nikhil, Parvaiz Ahmad Shiekh, Babita Yadav, Kumaravelu Jagavelu, Ashok Kumar
Bioactive Materials.2024; 33: 324. CrossRef
Anti-Malassezia globosa (MYA-4889, ATCC) activity of Thai propolis from the stingless bee Geniotrigona thoracica
Kawisara Konsila, Wanchai Assavalapsakul, Preecha Phuwapraisirisan, Chanpen Chanchao
Heliyon.2024; 10(8): e29421. CrossRef
Polyphenols and Their Nanoformulations as Potential Antibiofilm Agents Against Multidrug-Resistant Pathogens
Modawy EM Elkhalifa, Muhammad Ashraf, Alshebli Ahmed, Assad Usman, Alashary AE Hamdoon, Mohammed A Elawad, Meshari G Almalki, Osama F Mosa, Laziz N Niyazov, Muhammad Ayaz
Future Microbiology.2024; 19(3): 255. CrossRef
Chemical aspects of polyphenol-protein interactions and their antibacterial activity
Sanusi Shamsudeen Nassarawa, Gulzar Ahmad Nayik, S. Dutta Gupta, Franklin Ore Areche, Yash D. Jagdale, Mohammad Javed Ansari, Hassan A. Hemeg, Ammar AL-Farga, Saqer S. Alotaibi
Critical Reviews in Food Science and Nutrition.2023; 63(28): 9482. CrossRef
Efficacy of Elaeagnus umbellata leaves on prevention of cadmium-induced toxicity in HepG2 cells
Jae-Yeul Lee, Seun-Ah Yang, Won-Bin Bae
Korean Journal of Food Preservation.2023; 30(5): 797. CrossRef
Trewia nudiflora Linn, a Medicinal Plant: Allelopathic Potential and Characterization of Bioactive Compounds from Its Leaf Extracts
Mst. Rokeya Khatun, Shunya Tojo, Toshiaki Teruya, Hisashi Kato-Noguchi
Horticulturae.2023; 9(8): 897. CrossRef
Alkyl Gallates as Potential Antibiofilm Agents: A Review
Mahmoud Rayan, Saleh Abu Lafi, Mizied Falah, Tomas Kacergius, Agne Kirkliauskiene, Vika Gabe, Anwar Rayan
Molecules.2023; 28(4): 1751. CrossRef
Application of the herbal chemical marker ranking system (Herb MaRS) to the standardization of herbal raw materials: a case study
Bruhan Kaggwa, Godwin Anywar, Edson Ireeta Munanura, Raphael Wangalwa, Henry Kyeyune, Hedmon Okella, Fadhiru Pakoyo Kamba, Ogwang Patrick Engeu
BMC Complementary Medicine and Therapies.2023;[Epub] CrossRef
Simultaneous isoquercitin and gallic acid production of Aspergillus niger on Triphala byproduct under solid state fermentation in packed-bed bioreactor
Pattarabhorn Pakaweerachat, Worasaung Klinthong, Kazuhisa Ohtaguchi, Teerin Chysirichote
AIMS Agriculture and Food.2023; 8(2): 359. CrossRef
Antioxidant and antibacterial activity of Apis laboriosa honey against Salmonella enterica serovar Typhimurium
Weihua Tan, Yuanyuan Tian, Qingya Zhang, Siwei Miao, Wenrong Wu, Xiaoqing Miao, Haiou Kuang, Wenchao Yang
Frontiers in Nutrition.2023;[Epub] CrossRef
New Palladium(II) Complexes Containing Methyl Gallate and Octyl Gallate: Effect against Mycobacterium tuberculosis and Campylobacter jejuni
Raphael Tristão Cruvinel Silva, Micaela Guidotti-Takeuchi, Jéssica Laura Miranda Peixoto, Fernanda Manaia Demarqui, Ananda Paula Mori, Carolyne Ferreira Dumont, Gabriella Rayane Aparecida Ferreira, Gabriele de Menezes Pereira, Daise Aparecida Rossi, Pedro
Molecules.2023; 28(9): 3887. CrossRef
Methyl gallate: Review of pharmacological activity
Huaguo Liang, Qingsong Huang, Li Zou, Peng Wei, Jiazheng Lu, Yongli Zhang
Pharmacological Research.2023; 194: 106849. CrossRef
Assessing the Potential of Gallic Acid and Methyl Gallate to Enhance the Efficacy of β-Lactam Antibiotics against Methicillin-Resistant Staphylococcus aureus by Targeting β-Lactamase: In Silico and In Vitro Studies
Pimsumon Jiamboonsri, Chatchakorn Eurtivong, Sompit Wanwong
Antibiotics.2023; 12(11): 1622. CrossRef
Drug-Repurposing Screening Identifies a Gallic Acid Binding Site on SARS-CoV-2 Non-structural Protein 7
Yushu Gu, Miaomiao Liu, Bart L. Staker, Garry W. Buchko, Ronald J. Quinn
ACS Pharmacology & Translational Science.2023; 6(4): 578. CrossRef
Inhibition of Pseudomonas aeruginosa quorum sensing by methyl gallate from Mangifera indica
Nourhan G. Naga, Ahmed A. Zaki, Dalia E. El-Badan, Heba S. Rateb, Khaled M. Ghanem, Mona I. Shaaban
Scientific Reports.2023;[Epub] CrossRef
Polyphenolic natural products as photosensitizers for antimicrobial photodynamic therapy: recent advances and future prospects
Xiaoyun Wang, Lian Wang, Reza Fekrazad, Lu Zhang, Xian Jiang, Gu He, Xiang Wen
Frontiers in Immunology.2023;[Epub] CrossRef
Influence of Gallic Acid-Containing Mouth Spray on Dental Health and Oral Microbiota of Healthy Dogs: A Pilot Study
Nichaphat Thongma, Bhagavathi Sundaram Sivamaruthi, Muruganantham Bharathi, Chawin Tansrisook, Sartjin Peerajan, Kittidaj Tanongpitchayes, Natcha Chawnan, Subramanian Rashmi, Kriangkrai Thongkorn, Chaiyavat Chaiyasut
Veterinary Sciences.2023; 10(7): 424. CrossRef
Effects of Secondary Metabolites of Rice on Brown Planthopper and Its Symbionts
Ziyuan Deng, Chengling Lai, Jun Zhang, Fan Sun, Danting Li, Peiying Hao, Xuping Shentu, Kun Pang, Xiaoping Yu
International Journal of Molecular Sciences.2023; 25(1): 386. CrossRef
Pyrogallol impairs staphylococcal biofilm formation via induction of bacterial oxidative stress
Katharina H C Roese, Christina Torlone, Lauren A Cooper, Lee Esposito, Amy M Deveau, Ursula S R Röse, Kristin M Burkholder
Journal of Applied Microbiology.2023;[Epub] CrossRef
Influence of Gallic Acid-Containing Mouth Spray on Dental Health and Oral Microbiota of Healthy Cats—A Pilot Study
Chaiyavat Chaiyasut, Bhagavathi Sundaram Sivamaruthi, Muruganantham Bharathi, Chawin Tansrisook, Sartjin Peerajan, Khontaros Chaiyasut, Suchanat Khongtan, Kittidaj Tanongpitchayes, Nichaphat Thongma, Natcha Chawnan, Kriangkrai Thongkorn
Veterinary Sciences.2022; 9(7): 313. CrossRef
Gallic Acid Reactive Extraction with and without 1-Octanol as Phase Modifier: Experimental and Modeling
Alexandra Cristina Blaga, Elena Niculina Dragoi, Raluca Elena Munteanu, Dan Cascaval, Anca Irina Galaction
Fermentation.2022; 8(11): 633. CrossRef
Determination of time dependent antibacterial activities of curcumin, carvacrol and styrax liquidus on Salmonella Enteritidis
Erhan KEYVAN, Hidayet TUTUN, Hatice Ahu KAHRAMAN, Erdi ŞEN, Ahu DEMİRTAŞ, Soner DÖNMEZ, Ali Özhan AKYÜZ
Ankara Üniversitesi Veteriner Fakültesi Dergisi.2022; 69(4): 355. CrossRef
Experimental Glass Ionomer Cement Containing Gallic acid: Antibacterial Effect and Fluoride Release an in vitro Study
Saher M. Elsharkawy, Yasser F. Gomaa, Reem Gamal
Open Access Macedonian Journal of Medical Sciences.2022; 10(D): 131. CrossRef
Nutraceutical Profile of “Carosello” (Cucumis melo L.) Grown in an Out-of-Season Cycle under LEDs
Onofrio Davide Palmitessa, Miriana Durante, Annalisa Somma, Giovanni Mita, Massimiliano D’Imperio, Francesco Serio, Pietro Santamaria
Antioxidants.2022; 11(4): 777. CrossRef
Antibacterial Fractions from Erodium cicutarium Exposed—Clinical Strains of Staphylococcus aureus in Focus
Vanja Ljoljić Bilić, Uroš M. Gašić, Dušanka Milojković-Opsenica, Hrvoje Rimac, Jadranka Vuković Rodriguez, Josipa Vlainić, Diana Brlek-Gorski, Ivan Kosalec
Antibiotics.2022; 11(4): 492. CrossRef
Corchorus olitorius L. (Jute) leaf and seed extracts exerted high antibacterial activity against food and plant pathogenic bacteria
Özlem Darcansoy İşeri, Didem Aksoy Körpe, Feride Iffet Sahin, Evren Cabi, Mehmet Haberal
The EuroBiotech Journal.2022; 6(3): 105. CrossRef
Antibacterial Activity of Crocus sativus L. Petals Extracts against Foodborne Pathogenic and Spoilage Microorganisms, with a Special Focus on Clostridia
Sara Primavilla, Cinzia Pagano, Rossana Roila, Raffaella Branciari, David Ranucci, Andrea Valiani, Maurizio Ricci, Luana Perioli
Life.2022; 13(1): 60. CrossRef
Screen-printed electrode modified by Au/NH2-MIL-125(Ti) composite for electrochemical sensing performance of gallic acid in green tea and urine samples
K.V. Kavya, Stella Vargheese, Dhanaprabhu Pattappan, R.T. Rajendra Kumar, Yuvaraj Haldorai
Chemical Physics Letters.2022; 807: 140074. CrossRef
Discovery of a Novel Inhibitor Structure of Mycobacterium tuberculosis Isocitrate Lyase
Changyuan Duan, Qihua Jiang, Xue Jiang, Hongwei Zeng, Qiaomin Wu, Yang Yu, Xiaolan Yang
Molecules.2022; 27(8): 2447. CrossRef
New Perspectives on the Sustainable Employment of Chestnut Shells as Active Ingredient against Oral Mucositis: A First Screening
Ana Sofia Ferreira, Ana Margarida Silva, Diana Pinto, Manuela M. Moreira, Ricardo Ferraz, Jaroslava Švarc-Gajić, Paulo C. Costa, Cristina Delerue-Matos, Francisca Rodrigues
International Journal of Molecular Sciences.2022; 23(23): 14956. CrossRef
Gallic Acid Leads to Cell Death of Candida Albicans by the Apoptosis Mechanism
Ito Liberato, Leticia A Lino, Juan K D Souza, João B A Neto, Livia G A V Sá, Vitória P F Cabral, Cecília R Silva, Bruno C Cavalcanti, Manoel O Moraes, Valder N Freire, Hélio V N Júnior, Claudia R Andrade
Future Microbiology.2022; 17(8): 599. CrossRef
Influence of Green Tea Added to Cherry Wine on Phenolic Content, Antioxidant Activity and Alpha-Glucosidase Inhibition during an In Vitro Gastrointestinal Digestion
Małgorzata Lasik-Kurdyś, Małgorzata Gumienna, Barbara Górna, Noranizan Mohd Adzahan
Foods.2022; 11(20): 3298. CrossRef
Cytotoxic Effect of Puya chilensis Collected in Central Chile
César Echeverria-Echeverria, Aly Valderrama-Villarroel, Marcelo Ortega, Rodrigo A. Contreras, Gustavo E. Zúñiga, Leonor Alvarado-Soto, Rodrigo Ramírez-Tagle
Natural Product Communications.2022;[Epub] CrossRef
Microwave-assisted functionalization of graphene oxide with amino acid behaviour on the chemical constituents and specific molecular pathways of pearl millet grains under saline conditions
Noura E. Mahmoud, A.H. Hassan, Reda M. Abdelhameed
Plant Nano Biology.2022; 2: 100020. CrossRef
Effect of phenolic compounds and cold shock on survival and virulence of Escherichia coli pathotypes
Ana L. Ríos‐López, Norma Heredia, Santos García, José Á. Merino‐Mascorro, Luisa Y. Solís‐Soto, Jorge E. Dávila‐Aviña
Journal of Food Safety.2022;[Epub] CrossRef
Tailored silver nanoparticles capped with gallic acid and its potential toxicity via ROS mediated pathway against osteosarcoma cells
Shahnaz Majeed, Mohammed Danish, Norul Aini Zakariya, Rokiah Hashim, Mohammed Tahir Ansari, Sreenivas Patro Sisinthy
Materials Today Communications.2022; 32: 103844. CrossRef
Effects of antibacterial peptide-producing Bacillus subtilis, gallic acid, and cellulase on fermentation quality and bacterial community of whole-plant corn silage
Zhiheng Zhang, Yuqin Wang, Saiqiao Wang, Lu Zhao, Binglei Zhang, Wanhang Jia, Zhenhan Zhai, Lingping Zhao, Yuanxiao Li
Frontiers in Microbiology.2022;[Epub] CrossRef
On the mechanism behind enhanced antibacterial activity of alkyl gallate esters against foodborne pathogens and its application in Chinese icefish preservation
Yu-gang Shi, Run-run Zhang, Chen-min Zhu, Xian-rui Liang, Rammile Ettelaie, Lai Jiang, Shan Lin
Food Microbiology.2021; 99: 103817. CrossRef
Antimicrobial and antioxidant potential of a standardized Ayurvedic formulation explains its clinical efficacy as gargles in post-radiotherapy oral cancer patients
Sandeep Chavan, Sushama Bhuvad, Bhagyashri Kumbhlakar, Jyoti Auti, Tanhaji Walunj, Shridevi Pathak, Rahul Tanpure, Shweta Gujar, Jagdish Shinde, Arvind Kulkarni, Vidya Gupta, Vineeta Deshmukh, Sadanand Sardeshmukh
Journal of Herbal Medicine.2021; 30: 100510. CrossRef
Anticariogenic activities of Libidibia ferrea, gallic acid and ethyl gallate against Streptococcus mutans in biofilm model
Manuela Ribeiro Passos, Rafael Silva Almeida, Brenda Oliveira Lima, Jeisa Zielle de Souza Rodrigues, Nayara Silva de Macêdo Neres, Louise Soares Pita, Patrick D'Orleans Farias Marinho, Iago Almeida Santos, Jamile Pinheiro da Silva, Milena Cardoso Oliveira
Journal of Ethnopharmacology.2021; 274: 114059. CrossRef
Calcium‐Based Metal–Organic Frameworks and Their Potential Applications
Shikai Xian, Yuhan Lin, Hao Wang, Jing Li
Small.2021;[Epub] CrossRef
Mixed biofilms of pathogenic Candida-bacteria: regulation mechanisms and treatment strategies
Fazlurrahman Khan, Nilushi Indika Bamunuarachchi, Dung Thuy Nguyen Pham, Nazia Tabassum, Mohd Sajjad Ahmad Khan, Young-Mog Kim
Critical Reviews in Microbiology.2021; 47(6): 699. CrossRef
Green Approach in Synthesis of Bio-Inspired Materials
Anamarija Stanković, Martina Medvidović-Kosanović, Jasminka Kontrec, Branka Njegić Džakula
Crystals.2021; 11(10): 1243. CrossRef
Calcium Oxalate and Gallic Acid: Structural Characterization and Process Optimization toward Obtaining High Contents of Calcium Oxalate Monohydrate and Dihydrate
Silvija Šafranko, Sara Goman, Dominik Goman, Stela Jokić, Ida Delač Marion, Nives Matijaković Mlinarić, Atiđa Selmani, Martina Medvidović-Kosanović, Anamarija Stanković
Crystals.2021; 11(8): 954. CrossRef
Methyl gallate, gallic acid-derived compound, inhibit cell proliferation through increasing ROS production and apoptosis in hepatocellular carcinoma cells
Chien-Yu Huang, Yu-Jia Chang, Po-Li Wei, Chin-Sheng Hung, Weu Wang, Irina V. Lebedeva
PLOS ONE.2021; 16(3): e0248521. CrossRef
Galla Chinensis, a Traditional Chinese Medicine: Comprehensive review of botany, traditional uses, chemical composition, pharmacology and toxicology
Yuan-yuan Ren, Xiao-rui Zhang, Ting-na Li, Yi-jia Zeng, Jin Wang, Qin-wan Huang
Journal of Ethnopharmacology.2021; 278: 114247. CrossRef
Effects of Gallic Acid on Fermentation Parameters, Protein Fraction, and Bacterial Community of Whole Plant Soybean Silage
Cheng Wang, Mingyang Zheng, Shuo Wu, Xuan Zou, Xiaoyang Chen, Liangfa Ge, Qing Zhang
Frontiers in Microbiology.2021;[Epub] CrossRef
In vitro antibacterial activity of Loxostylis alata extracts and isolated compounds against Salmonella species
Dorcas A. Gado, Muna Ali Abdalla, Aroke S. Ahmed, Balungile Madikizela, Sanah M. Nkadimeng, Marthie M. Ehlers, Lyndy J. McGaw
BMC Complementary Medicine and Therapies.2021;[Epub] CrossRef
Impact of Foliar Application of Amino Acids on Total Phenols, Phenolic Acids Content of Different Mints Varieties under the Field Condition
Živilė Tarasevičienė, Aloyzas Velička, Aurelija Paulauskienė
Plants.2021; 10(3): 599. CrossRef
Influence of Gallic Acid and Thai Culinary Essential Oils on Antibacterial Activity of Nisin against Streptococcus mutans
Pimsumon Jiamboonsri, Pimpikar Kanchanadumkerng, Mohd Esa Norhaizan
Advances in Pharmacological and Pharmaceutical Sciences.2021; 2021: 1. CrossRef
Chinese gallnut (Galla chinensis) against Vibrio parahaemolyticus: In vitro activity and the use of medicated bath method to treat infected mud crab Scylla paramamosain
Qingyang Wu, Yang Jiang, Enzhu Chen, Changkao Mu, Khor Waiho
Aquaculture.2021; 539: 736632. CrossRef
HPLC-PDA-ESI-MS/MS Profiling and Anti-Biofilm Potential of Eucalyptussideroxylon Flowers
Mona M. Okba, Riham A. El-Shiekh, Mohammed Abu-Elghait, Mansour Sobeh, Rehab M. S. Ashour
Antibiotics.2021; 10(7): 761. CrossRef
Combating Biofilm by Targeting Its Formation and Dispersal Using Gallic Acid against Single and Multispecies Bacteria Causing Dental Plaque
Aqel Albutti, Muhammad Shoaib Gul, Muhammad Faisal Siddiqui, Farhana Maqbool, Fazal Adnan, Ihsan Ullah, Ziaur Rahman, Sadia Qayyum, Muhammad Ajmal Shah, Muhammad Salman
Pathogens.2021; 10(11): 1486. CrossRef
Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation
Yu-gang Shi, Run-run Zhang, Chen-min Zhu, Ming-feng Xu, Qing Gu, Rammile Ettelaie, Shan Lin, Yi-fan Wang, Xin-yi Leng
Food Chemistry.2021; 346: 128949. CrossRef
Chromatographic and Spectrophotometric Determination of Some Phenolic Compounds in Tridax procumbens Linn Stem
Akinshola Olabamiji Akinola, Funmilayo Enitan Adelowo
Chemistry Africa.2021; 4(1): 103. CrossRef
Bacterial ClpP Protease Is a Potential Target for Methyl Gallate
Dehong Zheng, Yanan Xu, Gaoqing Yuan, Xiaogang Wu, Qiqin Li
Frontiers in Microbiology.2021;[Epub] CrossRef
A coaxially structured trilayered gallic acid-based antioxidant vascular graft for treating coronary artery disease
Ankita Das, Parvaiz Ahmad Shiekh, Ashok Kumar
European Polymer Journal.2021; 143: 110203. CrossRef
Efficacy of germination and probiotic fermentation on underutilized cereal and millet grains
Savita Budhwar, Kashika Sethi, Manali Chakraborty
Food Production, Processing and Nutrition.2020;[Epub] CrossRef
4-Ethoxybenzoic acid inhibits Staphylococcus aureus biofilm formation and potentiates biofilm sensitivity to vancomycin
Mariya Campbell, Chih-Yun Cho, Andrew Ho, Jye-Yu Huang, Brooke Martin, Eric S. Gilbert
International Journal of Antimicrobial Agents.2020; 56(3): 106086. CrossRef
Potential effects of Psidium sp., Mangifera sp., Mentha sp. and its mixture (PEM) in reducing bacterial populations in biofilms, adherence and acid production of S. sanguinis and S. mutans
Zaleha Shafiei, Zubaidah Haji Abdul Rahim, Koshy Philip, Nalina Thurairajah, Hashim Yaacob
Archives of Oral Biology.2020; 109: 104554. CrossRef
The effect of polyphenol-containing solutions on in situ biofilm formation on enamel and dentin
Qingping Xi, Wiebke Hoth-Hannig, Shuli Deng, Xiaoting Jin, Baiping Fu, Matthias Hannig
Journal of Dentistry.2020; 102: 103482. CrossRef
Pharmacological Research Progress on Antimicrobial Infection of Gallic Acid
娇尹
Advances in Clinical Medicine.2020; 10(12): 2940. CrossRef
Anti-oxidant, anti-inflammatory, and anti-bacterial effects of extracts from Elaeagnus umbellata leaves obtained using different extract conditions
Ha-Rin Kang, Jong-Kang Jung, Se-Ho Park, Jae-Yeul Lee, Seun-Ah Yang
Korean Journal of Food Preservation.2020; 27(3): 374. CrossRef
Comparative effects of nisin and monensin on pure cultures of rumen bacteria
Ahu DEMİRTAŞ
Veteriner Hekimler Derneği Dergisi.2020; 91(1): 1. CrossRef
Effects of dietary gallic acid on growth performance, diarrhea incidence, intestinal morphology, plasma antioxidant indices, and immune response in weaned piglets
L. Cai, Y.P. Li, Z.X. Wei, X.L. Li, X.R. Jiang
Animal Feed Science and Technology.2020; 261: 114391. CrossRef
Residues from the Brazilian pepper tree (Schinus terebinthifolia Raddi) processing industry: Chemical profile and antimicrobial activity of extracts against hospital bacteria
Rodrigo Borges de Araujo Gomes, Erica Santana de Souza, Nataly Senna Gerhardt Barraqui, Cristina Luz Tosta, Ana Paula Ferreira Nunes, Ricardo Pinto Schuenck, Fabiana Gomes Ruas, José Aires Ventura, Paulo Roberto Filgueiras, Ricardo Machado Kuster
Industrial Crops and Products.2020; 143: 111430. CrossRef
Can an entomopathogenic nematode serve, as proxy for strongyles, in assessing the anthelmintic effects of phenolic compounds?
Serge Yan Landau, Velayudhan Satheeja Santhi, Itamar Glazer, Liora Salame, Hussein Muklada, Manal Haj-Zaroubi, Safaa Awwad, Alex Markovics, Hassan Azaizeh
Experimental Parasitology.2020; 209: 107811. CrossRef
Polyphenols of Honeybee Origin with Applications in Dental Medicine
Carmen Curuțiu, Lia Mara Dițu, Alexandru Mihai Grumezescu, Alina Maria Holban
Antibiotics.2020; 9(12): 856. CrossRef
Polyphenols Attenuate Highly-Glycosylated Haemoglobin-Induced Damage in Human Peritoneal Mesothelial Cells
Carolina Sánchez-Rodríguez, Concepción Peiró, Leocadio Rodríguez-Mañas, Julián Nevado
Antioxidants.2020; 9(7): 572. CrossRef
IN VITRO ANTIMICROBIAL ACTIVITY OF NATURAL SUBSTANCES CONVENIENT FOR USE IN ANIMAL BREEDING INSTEAD OF ANTIBIOTICS
Rudolf Kukla, Jaroslava Mazurova, Ilona Krovakova, Eva Slehova, Radek Sleha, Miroslav Rozkot, Lubomir Opletal
Military Medical Science Letters.2020; 89(1): 2. CrossRef
In vitro activities of Acacia nilotica (L.) Delile bark fractions against Oral Bacteria, Glucosyltransferase and as antioxidant
Ali Mahmoud Muddathir, Ebtihal Abdalla M. Mohieldin, Tohru Mitsunaga
BMC Complementary Medicine and Therapies.2020;[Epub] CrossRef
Epigallocatechin gallate and gallic acid affect colonization of abiotic surfaces by oral bacteria
Yi Wang, Antonia T.W. Lam
Archives of Oral Biology.2020; 120: 104922. CrossRef
Evaluation of the pharmacokinetic-pharmacodynamic integration of marbofloxacin in combination with methyl gallate against Salmonella Typhimurium in rats
Biruk Tesfaye Birhanu, Eon-Bee Lee, Seung-Chun Park, Praveen Rishi
PLOS ONE.2020; 15(6): e0234211. CrossRef
Nickel‐Based Metal‐Organic Framework/Crosslinked Tubular Poly(3,4‐ethylenedioxythiophene) Composite as an Electrocatalyst for the Detection of Gallic Acid and Tinidazole
Haixu Wang, Xiaogeng Feng, Xiangjie Bo, Ming Zhou, Liping Guo
ChemElectroChem.2020; 7(19): 4031. CrossRef
Anticariogenic activity of Nelumbo nucifera leaf extract in oral healthcare
Haeng-Eun Lee, Man-Seok Han, Seoul-Hee Nam, Jungsoo Han
Technology and Health Care.2019; 27(5): 487. CrossRef
Optimization of antibacterial extract from lacquer tree (Rhus verniciflua Stokes) using response surface methodology and its efficacy in controlling edwardsiellosis of olive flounder (Paralichthys olivaceus)
Jae-Woong Lim, Su-Mi Shin, Sung-Ju Jung, Mi Kyeong Lee, So Young Kang
Aquaculture.2019; 502: 40. CrossRef
Inactivation of Alpha-2-Macroglobulin by Photo-Illuminated Gallic Acid
Tooba Siddiqui, Mohammad Khalid Zia, Syed Saqib Ali, Haseeb Ahsan, Fahim Halim Khan
Journal of Fluorescence.2019; 29(4): 969. CrossRef
The Modern Use of an Ancient Plant: Exploring the Antioxidant and Nutraceutical Potential of the Maltese Mushroom (Cynomorium Coccineum L.)
Paolo Zucca, Sidonie Bellot, Antonio Rescigno
Antioxidants.2019; 8(8): 289. CrossRef
Gallic acid‐loaded electrospun cellulose acetate nanofibers as potential wound dressing materials
Patcharaporn Wutticharoenmongkol, Pornchita Hannirojram, Pimchanok Nuthong
Polymers for Advanced Technologies.2019; 30(4): 1135. CrossRef
Interaction of Bovine Serum Albumin with Propyl Gallate and Methyl Gallate Investigated by Fluorescence Spectroscopy
Seong‐June Lee, Han‐Gook Cho, Byeong‐Seo Cheong
Bulletin of the Korean Chemical Society.2019; 40(4): 344. CrossRef
Metal nanoparticles synthesis through natural phenolic acids
Seyed Mohammad Amini, Abolfazl Akbari
IET Nanobiotechnology.2019; 13(8): 771. CrossRef
Reshaped as polyester-based nanoparticles, gallic acid inhibits platelet aggregation, reactive oxygen species production and multi-resistant Gram-positive bacteria with an efficiency never obtained
Silvana Alfei, Maria Grazia Signorello, Anna Schito, Silvia Catena, Federica Turrini
Nanoscale Advances.2019; 1(10): 4148. CrossRef
Persulfated flavonoids accelerated re-endothelialization and improved blood compatibility for vascular medical implants
Tarek M. Bedair, Hanan M. Bedair, Kyoung-Won Ko, Wooram Park, Yoon Ki Joung, Dong Keun Han
Colloids and Surfaces B: Biointerfaces.2019; 181: 174. CrossRef
Galla chinensisextracts and calcium induce remineralization and antibacterial effects of enamel in aStreptococcus mutansbiofilm model
Eun-Jeong Kim, Bo-Hyoung Jin
Journal of Korean Academy of Oral Health.2018; 42(3): 90. CrossRef
Transcriptome analysis reveals GA induced apoptosis in HCT116 human colon cancer cells through calcium and p53 signal pathways
Chen Yang, Xiaoyu Xie, Hu Tang, Xuyan Dong, Xiaodong Zhang, Fenghong Huang
RSC Advances.2018; 8(22): 12449. CrossRef
Antimicrobial and Cytotoxic Activity of Dihydrobenzofuran Neolignans
Murilo J. Fukui, Herbert J. Dias, Marcela E. Severiano, Maria G. M. de Souza, Pollyanna F. de Oliveira, Sérgio R. Ambrósio, Carlos H. G. Martins, Denise C. Tavares, Antônio E. M. Crotti
ChemistrySelect.2018; 3(6): 1836. CrossRef
In Vitro Anthelmintic Activity of Methanolic Extract from Caesalpinia coriaria J. Willd Fruits against Haemonchus contortus Eggs and Infective Larvae
X. De Jesús-Martínez, A. Olmedo-Juárez, J. Olivares-Pérez, A. Zamilpa, P. Mendoza de Gives, M. E. López-Arellano, S. Rojas-Hernández, A. Villa-Mancera, L. M. Camacho-Díaz, M. Cipriano-Salazar
BioMed Research International.2018; 2018: 1. CrossRef
Inhibiting foodborne pathogens Vibrio parahaemolyticus and Listeria monocytogenes using extracts from traditional medicine: Chinese gallnut, pomegranate peel, Baikal skullcap root and forsythia fruit
Jian Wu, Katheryn M. Goodrich, Joseph D. Eifert, Michael L. Jahncke, Sean F. O’Keefe, Gregory E. Welbaum, Andrew P. Neilson
Open Agriculture.2018; 3(1): 163. CrossRef
Bioactivities of Phenolics by Focusing on Suppression of Chronic Diseases: A Review
Fereidoon Shahidi, JuDong Yeo
International Journal of Molecular Sciences.2018; 19(6): 1573. CrossRef
Effects of gallic acid on signaling kinases in murine macrophages and immune modulation against Brucella abortus 544 infection in mice
Alisha Wehdnesday Bernardo Reyes, Lauren Togonon Arayan, Huynh Tan Hop, Tran Xuan Ngoc Huy, Son Hai Vu, WonGi Min, Hu Jang Lee, Suk Kim
Microbial Pathogenesis.2018; 119: 255. CrossRef
Evaluation of phytotoxic activity of leaf and stem extracts and identification of a phytotoxic substance from Caesalpinia mimosoides Lamk.
Sutjaritpan Boonmee, Arihiro Iwasaki, Kiyotake Suenaga, Hisashi Kato-Noguchi
Theoretical and Experimental Plant Physiology.2018; 30(2): 129. CrossRef
Production of phenolic compounds and biosugars from flower resources via several extraction processes
Ly Thi Phi Trinh, Yong-Soo Choi, Hyeun-Jong Bae
Industrial Crops and Products.2018; 125: 261. CrossRef
Neuroprotective effects of paeoniflorin in neurodegenerative diseases of the central nervous system
Azadeh Manayi, Sahar Omidpanah, Davide Barreca, Silvana Ficarra, Maria Daglia, Seyed Fazel Nabavi, Seyed Mohammad Nabavi
Phytochemistry Reviews.2017; 16(6): 1173. CrossRef
The specific anti-biofilm effect of gallic acid on Staphylococcus aureus by regulating the expression of the ica operon
Meihui Liu, Xiaoxia Wu, Jianke Li, Liu Liu, Runguang Zhang, Dongyan Shao, Xiaodan Du
Food Control.2017; 73: 613. CrossRef
Inhibitory capacity of Rhus coriaria L. extract and its major component methyl gallate on Streptococcus mutans biofilm formation by optical profilometry: Potential applications for oral health
Tomas Kacergius, Saleh Abu-Lafi, Agne Kirkliauskiene, Vika Gabe, Azmi Adawi, Mahmoud Rayan, Mutaz Qutob, Rimantas Stukas, Algirdas Utkus, Mouhammad Zeidan, Anwar Rayan
Molecular Medicine Reports.2017; 16(1): 949. CrossRef
α-Farnesene and ocimene induce metabolite changes by volatile signaling in neighboring tea ( Camellia sinensis ) plants
Lanting Zeng, Yinyin Liao, Jianlong Li, Ying Zhou, Jinchi Tang, Fang Dong, Ziyin Yang
Plant Science.2017; 264: 29. CrossRef
Antimicrobial effect ofPrunus mumeextracts against cariogenic bacteria
Jung-Sun Lee, Ki-Ho Chung
Journal of Korean Academy of Oral Health.2017; 41(1): 65. CrossRef
Marsdenia tenacissima extract suppresses tumor growth and angiogenesis in A20 mouse lymphoma
Xingbin Dai, Yanhua Ji, Pengjun Jiang, Xuemei Sun
Oncology Letters.2017; 13(5): 2897. CrossRef
Gallic acid inhibits the growth of calf pulmonary arterial endothelial cells through cell death and glutathione depletion
Woo Hyun Park
Molecular Medicine Reports.2017; 16(5): 7805. CrossRef
Protective effect of Gallic acid on doxorubicin-induced testicular and epididymal toxicity
M.J. Olusoji, O. M. Oyeyemi, E. R. Asenuga, T. O. Omobowale, O. L. Ajayi, A. A. Oyagbemi
Andrologia.2017; 49(4): e12635. CrossRef
Derivatives of alkyl gallate triphenylphosphonium exhibit antitumor activity in a syngeneic murine model of mammary adenocarcinoma
Liliana Peredo-Silva, Sebastián Fuentes-Retamal, Cristian Sandoval-Acuña, Mario Pavani, Juan D. Maya, Vicente Castro-Castillo, Matías Madrid-Rojas, Solange Rebolledo, Ulrike Kemmerling, Eduardo Parra, Jorge Ferreira
Toxicology and Applied Pharmacology.2017; 329: 334. CrossRef
Gallic acid induces G1 phase arrest and apoptosis of triple-negative breast cancer cell MDA-MB-231 via p38 mitogen-activated protein kinase/p21/p27 axis
Hsiang-Lin Lee, Chun-Shiang Lin, Shao-Hsuan Kao, Ming-Chih Chou
Anti-Cancer Drugs.2017; 28(10): 1150. CrossRef
Gallic acid induces HeLa cell death via increasing GSH depletion rather than ROS levels
Woo Hyun Park
Oncology Reports.2017; 37(2): 1277. CrossRef
Octyl gallate, a food additive with potential beneficial properties to treat Helicobacter pylori infection
Vanessa Gonçalves Wolf, Cibele Bonacorsi, Maria Stella Gonçalves Raddi, Luiz Marcos da Fonseca, Valdecir Farias Ximenes
Food & Function.2017; 8(7): 2500. CrossRef
The Effect of Pelargonium endlicherianum Fenzl. root extracts on formation of nanoparticles and their antimicrobial activities
Gökçe Şeker Karatoprak, Gamze Aydin, Berrak Altinsoy, Cevahir Altinkaynak, Müberra Koşar, Ismail Ocsoy
Enzyme and Microbial Technology.2017; 97: 21. CrossRef
Crystal structure dependent in vitro antioxidant activity of biocompatible calcium gallate MOFs
Tania Hidalgo, Lucy Cooper, Martin Gorman, Tamara Lozano-Fernández, Rosana Simón-Vázquez, Georges Mouchaham, Jérome Marrot, Nathalie Guillou, Christian Serre, Pierre Fertey, África González-Fernández, Thomas Devic, Patricia Horcajada
Journal of Materials Chemistry B.2017; 5(15): 2813. CrossRef
Fluorescein isothiocyanate‐dyed mesoporous silica nanoparticles for tracking antioxidant delivery
Ladan Rashidi, Fariba Ganji, Ebrahim Vasheghani‐Farahani
IET Nanobiotechnology.2017; 11(4): 454. CrossRef
Recent advances to accelerate re-endothelialization for vascular stents
Tarek M Bedair, Mahmoud A ElNaggar, Yoon Ki Joung, Dong Keun Han
Journal of Tissue Engineering.2017;[Epub] CrossRef
On mechanism behind UV-A light enhanced antibacterial activity of gallic acid and propyl gallate against Escherichia coli O157:H7
Qingyang Wang, Erick Falcao de Oliveira, Solmaz Alborzi, Luis J. Bastarrachea, Rohan V. Tikekar
Scientific Reports.2017;[Epub] CrossRef
Biofilms as “Connectors” for Oral and Systems Medicine: A New Opportunity for Biomarkers, Molecular Targets, and Bacterial Eradication
Herman O. Sintim, Ulvi Kahraman Gürsoy
OMICS: A Journal of Integrative Biology.2016; 20(1): 3. CrossRef
Insoluble-Bound Phenolics in Food
Fereidoon Shahidi, JuDong Yeo
Molecules.2016; 21(9): 1216. CrossRef
Use of organic acids for prevention and removal of Bacillus subtilis biofilms on food contact surfaces
Meltem Yesilcimen Akbas, Seyda Cag
Food Science and Technology International.2016; 22(7): 587. CrossRef
Gallic acid as a selective anticancer agent that induces apoptosis in SMMC-7721 human hepatocellular carcinoma cells
GUOJUN SUN, SHUQIN ZHANG, YANRU XIE, ZIYU ZHANG, WENJING ZHAO
Oncology Letters.2016; 11(1): 150. CrossRef
Gallic acid induces apoptosis in EGFR-mutant non-small cell lung cancers by accelerating EGFR turnover
Boas Nam, Jin Kyung Rho, Dong-Myung Shin, Jaekyoung Son
Bioorganic & Medicinal Chemistry Letters.2016; 26(19): 4571. CrossRef
Improving succinic acid production by Actinobacillus succinogenes from raw industrial carob pods
Margarida Carvalho, Christophe Roca, Maria A.M. Reis
Bioresource Technology.2016; 218: 491. CrossRef
Skin penetration and antioxidant effect of cosmeto-textiles with gallic acid
C. Alonso, M. Martí, C. Barba, M. Lis, L. Rubio, L. Coderch
Journal of Photochemistry and Photobiology B: Biology.2016; 156: 50. CrossRef
Complexation and molecular modeling studies of europium(III)–gallic acid–amino acid complexes
Mohamed Taha, Imran Khan, João A.P. Coutinho
Journal of Inorganic Biochemistry.2016; 157: 25. CrossRef
Galla chinensis Compounds Remineralize Enamel Caries Lesions in a Rat Model
Tie-Ting Zhang, Hui-Jing Guo, Xue-Jun Liu, Jin-Pu Chu, Xue-Dong Zhou
Caries Research.2016; 50(2): 159. CrossRef
Single-molecule interaction force measurements of catechol analog monomers and synthesis of adhesive polymer using the results
Shougo Kinugawa, Siqian Wang, Shu Taira, Akihiko Tsuge, Daisaku Kaneko
Polymer Journal.2016; 48(6): 715. CrossRef
Antioxidant activities of novel galloyl phytosterols evaluated by human erythrocytes with the aid of confocal microscopy imaging
Songbai Liu, Huiying Hu, Cheng Li
Journal of Functional Foods.2016; 22: 224. CrossRef
Effects of aluminum oxide (Al2O3) nanoparticles on ECG, myocardial inflammatory cytokines, redox state, and connexin 43 and lipid profile in rats: possible cardioprotective effect of gallic acid
El-Hussainy M.A. El-Hussainy, Abdelaziz M. Hussein, Azza Abdel-Aziz, Ibrahim El-Mehasseb
Canadian Journal of Physiology and Pharmacology.2016; 94(8): 868. CrossRef
Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors
Kapil Upadhyaya, Hamidullah Hamidullah, Kartikey Singh, Ashutosh Arun, Mahendra Shukla, Neetika Srivastava, Raghib Ashraf, Abhisheak Sharma, Rohit Mahar, Sanjeev K. Shukla, Jayanta Sarkar, Ravishankar Ramachandran, Jawahar Lal, Rituraj Konwar, Rama Pati T
Organic & Biomolecular Chemistry.2016; 14(4): 1338. CrossRef
Molecular Mechanisms of Inhibition of Streptococcus Species by Phytochemicals
Soheila Abachi, Song Lee, H. Rupasinghe
Molecules.2016; 21(2): 215. CrossRef
Gallic acid grafting effect on delivery performance and antiglaucoma efficacy of antioxidant-functionalized intracameral pilocarpine carriers
Shih-Feng Chou, Li-Jyuan Luo, Jui-Yang Lai
Acta Biomaterialia.2016; 38: 116. CrossRef
Plant Natural Products Targeting Bacterial Virulence Factors
Laura Nunes Silva, Karine Rigon Zimmer, Alexandre José Macedo, Danielle Silva Trentin
Chemical Reviews.2016; 116(16): 9162. CrossRef
Antibiofilm Activity of Plant Polyphenols
Lívia Slobodníková, Silvia Fialová, Katarína Rendeková, Ján Kováč, Pavel Mučaji
Molecules.2016; 21(12): 1717. CrossRef
Methyl gallate limits infection in mice challenged with Brucella abortus while enhancing the inflammatory response
A.W.B. Reyes, D.G. Kim, H.L.T. Simborio, H.T. Hop, L.T. Arayan, W. Min, J.J. Lee, H.H. Chang, S. Kim
Journal of Applied Microbiology.2016; 120(3): 552. CrossRef
Identification and partial purification of antibacterial compounds againstStreptococcus mutansfromGalla Rhois
Ae-Ri Shin, Seung-Ho Ohk, Choong-Ho Choi, Suk-Jin Hong
Journal of Korean Academy of Oral Health.2016; 40(1): 3. CrossRef
Co-Metabolic Degradation of β-Cypermethrin and 3-Phenoxybenzoic Acid by Co-Culture of Bacillus licheniformis B-1 and Aspergillus oryzae M-4
Jiayuan Zhao, Yuanlong Chi, Yingchao Xu, Dongying Jia, Kai Yao, Pankaj Kumar Arora
PLOS ONE.2016; 11(11): e0166796. CrossRef
Green synthesis of gold and silver nanoparticles using gallic acid: catalytic activity and conversion yield toward the 4-nitrophenol reduction reaction
Jisu Park, Song-Hyun Cha, Seonho Cho, Youmie Park
Journal of Nanoparticle Research.2016;[Epub] CrossRef
Characterization of the bioactive constituents of Nymphaea alba rhizomes and evaluation of anti-biofilm as well as antioxidant and cytotoxic properties
Omar Bakr Riham, Wasfi Reham, Swilam Noha, Ezz Sallam Ibrahim
Journal of Medicinal Plants Research.2016; 10(26): 390. CrossRef
Selected dietary (poly)phenols inhibit periodontal pathogen growth and biofilm formation
Muhammad Shahzad, Emma Millhouse, Shauna Culshaw, Christine A. Edwards, Gordon Ramage, Emilie Combet
Food & Function.2015; 6(3): 719. CrossRef
Commercial Lawsonia inermis L. dried leaves and processed powder: Phytochemical composition, antioxidant, antibacterial, and allelopathic activities
Karima Dhaouadi, Walid Meliti, Sana Dallali, Manel Belkhir, Saloua Ouerghemmi, Houcine Sebei, Sami Fattouch
Industrial Crops and Products.2015; 77: 544. CrossRef
Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties
Laura Marín, Elisa M. Miguélez, Claudio J. Villar, Felipe Lombó
BioMed Research International.2015; 2015: 1. CrossRef
Use of natural substances for boar semen decontamination
J. Mazurova, R. Kukla, M. Rozkot, A. Lustykova, E. Slehova, R. Sleha, J. Lipensky, L. Opletal
Veterinární medicína.2015; 60(5): 235. CrossRef
Green synthesis of gallic acid-coated silver nanoparticles with high antimicrobial activity and low cytotoxicity to normal cells
Dan Li, Zuojia Liu, Ye Yuan, Yawen Liu, Fenglan Niu
Process Biochemistry.2015; 50(3): 357. CrossRef
Dietary Polyphenols in Prevention and Treatment of Prostate Cancer
Rahul Lall, Deeba Syed, Vaqar Adhami, Mohammad Khan, Hasan Mukhtar
International Journal of Molecular Sciences.2015; 16(2): 3350. CrossRef
Anti-carious Effects ofGalla chinensis: A Systematic Review
Tieting Zhang, Jinpu Chu, Xuedong Zhou
Phytotherapy Research.2015; 29(12): 1837. CrossRef
Optimization of metronidazole sustained-release films using D-optimal design
Jomjai Peerapattana, Teeraphat Ngamsupsiri, Nopadol Cheucharoenvasuchai, Charnnarong Saikaew
International Journal of Pharmaceutics.2015; 484(1-2): 1. CrossRef
Isolation and characterization of gallic acid and methyl gallate from the seed coats of Givotia rottleriformis Griff. and their anti-proliferative effect on human epidermoid carcinoma A431 cells
Samuel Kamatham, Naresh Kumar, Padmaja Gudipalli
Toxicology Reports.2015; 2: 520. CrossRef
Synthesis, Antiproliferative Activity and Molecular Properties Predictions of Galloyl Derivatives
Marciane Maximo da Silva, Marina Comin, Thiago Santos Duarte, Mary Foglio, João De Carvalho, Maria Do Carmo Vieira, Anelise Nazari Formagio
Molecules.2015; 20(4): 5360. CrossRef
Molecular adaptation of Lactobacillus plantarum WCFS1 to gallic acid revealed by genome-scale transcriptomic signature and physiological analysis
Inés Reverón, Blanca de las Rivas, Ruth Matesanz, Rosario Muñoz, Félix López de Felipe
Microbial Cell Factories.2015;[Epub] CrossRef
Inhibition of Gallic Acid on the Growth and Biofilm Formation of Escherichia coli and Streptococcus mutans
Dongyan Shao, Jing Li, Ji Li, Ruihua Tang, Liu Liu, Junling Shi, Qingsheng Huang, Hui Yang
Journal of Food Science.2015;[Epub] CrossRef
Phenolic Compounds from Liquidambar formosana Fruits as Monoamine Oxidase Inhibitors
Zhong-duo Yang, Ji-bei Liang, Wei-Wei Xue, Jie Sheng, Yin Shi, Xiao-Jun Yao, Jin Ren, Lian Liu
Chemistry of Natural Compounds.2014; 50(6): 1118. CrossRef
Design and straightforward synthesis of novel galloyl phytosterols with excellent antioxidant activity
Yuanqing Fu, Yan Zhang, Huiying Hu, Ying Chen, Rong Wang, Duo Li, Songbai Liu
Food Chemistry.2014; 163: 171. CrossRef
Polyphenol-rich extract of Nelumbo nucifera leaves inhibits alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and anti-inflammation in C57BL/6J mice
Chang-Chieh Tang, Wea-Lung Lin, Yi-Ju Lee, Yu-Chi Tang, Chau-Jong Wang
Food & Function.2014; 5(4): 678. CrossRef
Isolation and characterization of antimicrobial compounds from Terminalia phanerophlebia Engl. & Diels leaf extracts
B. Madikizela, M.A. Aderogba, J.F. Finnie, J. Van Staden
Journal of Ethnopharmacology.2014; 156: 228. CrossRef
Sucrose supplementation during traditional carob syrup processing affected its chemical characteristics and biological activities
Karima Dhaouadi, Manel Belkhir, Ismail Akinocho, Faten Raboudi, David Pamies, Enrique Barrajón, Carmen Estevan, Sami Fattouch
LWT - Food Science and Technology.2014; 57(1): 1. CrossRef
Antimicrobial Activity of Antrodia camphorata Extracts against Oral Bacteria
Hsiu-Man Lien, Chin-Jui Tseng, Chao-Lu Huang, Yu-Ting Lin, Chia-Chang Chen, Ya-Yun Lai, Yuan-Soon Ho
PLoS ONE.2014; 9(8): e105286. CrossRef
Inhibitory effect of the carnosine-gallic acid synthetic peptide on MMP-2 and MMP-9 in human fibrosarcoma HT1080 cells
Sung-Rae Kim, Tae-Kil Eom, Hee-Guk Byun
Journal of Peptide Science.2014; 20(9): 716. CrossRef
Topical application of Gallic acid suppresses the 7,12-DMBA/Croton oil induced two-step skin carcinogenesis by modulating anti-oxidants and MMP-2/MMP-9 in Swiss albino mice
Vimala Subramanian, Balaji Venkatesan, Anusha Tumala, Elangovan Vellaichamy
Food and Chemical Toxicology.2014; 66: 44. CrossRef
Gallic Acid Tailoring Surface Functionalities of Plasma-Polymerized Allylamine-Coated 316L SS to Selectively Direct Vascular Endothelial and Smooth Muscle Cell Fate for Enhanced Endothelialization
Zhilu Yang, Kaiqin Xiong, Pengkai Qi, Ying Yang, Qiufen Tu, Jin Wang, Nan Huang
ACS Applied Materials & Interfaces.2014; 6(4): 2647. CrossRef
Antibacterial mechanisms of methyl gallate against Ralstonia solanacearum
Wan-Wan Fan, Gao-Qing Yuan, Qi-Qin Li, Wei Lin
Australasian Plant Pathology.2014; 43(1): 1. CrossRef
Antiadherent activity of Schinus terebinthifolius and Croton urucurana extracts on in vitro biofilm formation of Candida albicans and Streptococcus mutans
Dicler S.V. Barbieri, Fabiana Tonial, Patricia V.A. Lopez, Beatriz H.L.N. Sales Maia, Germana D. Santos, Marina O. Ribas, Chirlei Glienke, Vania A. Vicente
Archives of Oral Biology.2014; 59(9): 887. CrossRef
Antibacterial and Antidiarrheal Activities of Plant Products against Enterotoxinogenic Escherichia coli
J. Dubreuil
Toxins.2013; 5(11): 2009. CrossRef
Anti-Depressant Like Effect of Methyl Gallate Isolated fromAcer barbinervein Mice
Jin-Koo Lee
The Korean Journal of Physiology & Pharmacology.2013; 17(5): 441. CrossRef
Gallic acid provokes DNA damage and suppresses DNA repair gene expression in human prostate cancer PC‐3 cells
Kuo‐Ching Liu, Heng‐Chien Ho, An‐Cheng Huang, Bin‐Chuan Ji, Hui‐Yi Lin, Fu‐Shin Chueh, Jai‐Sing Yang, Chi‐Cheng Lu, Jo‐Hua Chiang, Menghsiao Meng, Jing‐Gung Chung
Environmental Toxicology.2013; 28(10): 579. CrossRef
Antibacterial Effects of Galla Rhois Extract against Streptococcus suis Infection in Mice
Chun-Nam Cha, Eun-Ah Yu, Eun-Kee Park, Hyunju Choi, Suk Kim, Hu Jang Lee
Journal of Food Hygiene and Safety.2013; 28(2): 95. CrossRef
Effect of Gallotannins Derived from Sedum takesimense on Tomato Bacterial Wilt
Thuy Thu Vu, Jin-Cheol Kim, Yong Ho Choi, Gyung Ja Choi, Kyoung Soo Jang, Tae Ho Choi, Tae Mi Yoon, Seon-Woo Lee
Plant Disease.2013; 97(12): 1593. CrossRef
Catechin-incorporated dental copolymers inhibit growth of Streptococcus mutans
Alexandra Mankovskaia, Celine M. Levesque, Anuradha Prakki
Journal of Applied Oral Science.2013; 21(2): 203. CrossRef
MAPK inhibitors augment gallic acid-induced A549 lung cancer cell death through the enhancement of glutathione depletion
WOO HYUN PARK, SUHN HEE KIM
Oncology Reports.2013; 30(1): 513. CrossRef
Biomimetic Formation of Pd and Au-Pd Nanocomposites and their Catalytic Applications
Nazmul H. Sarker, Stacey N. Barnaby, Aaron P. Dowdell, Nako Nakatsuka, Ipsita A. Banerjee
Soft Materials.2013; 11(4): 403. CrossRef
Construction of Polyfunctional Coatings Assisted by Gallic Acid to Facilitate Co-Immobilization of Diverse Biomolecules
Zhilu Yang, Ying Yang, Wei Yan, Qiufen Tu, Jin Wang, Nan Huang
ACS Applied Materials & Interfaces.2013; 5(21): 10495. CrossRef
Antitumor activity of methyl gallate by inhibition of focal adhesion formation and Akt phosphorylation in glioma cells
Sang-Hyun Lee, Jin Kyu Kim, Dae Won Kim, Hyun Sook Hwang, Won Sik Eum, Jinseu Park, Kyu Hyung Han, Joa Sub Oh, Soo Young Choi
Biochimica et Biophysica Acta (BBA) - General Subjects.2013; 1830(8): 4017. CrossRef
Antimetastatic activity and low systemic toxicity of tetradecyl gallate in a preclinical melanoma mouse model
Claudriana Locatelli, Deborah Regina Carvalho, Alessandra Mascarello, Clarissa Amorin Silva de Cordova, Rosendo Augusto Yunes, Ricardo Jose Nunes, Celso Pilati, Tânia Beatriz Creczynski-Pasa
Investigational New Drugs.2012; 30(3): 870. CrossRef
Chemical composition of Galla chinensis extract and the effect of its main component(s) on the prevention of enamel demineralization in vitro
Xue-Lian Huang, Ming-Dong Liu, Ji-Yao Li, Xue-Dong Zhou, Jacob M ten Cate
International Journal of Oral Science.2012; 4(3): 146. CrossRef
Anticoccidial effect of supplemental dietaryGalla Rhoisagainst infection withEimeria tenellain chickens
Jin Ju Lee, Dong Hyeok Kim, Jeong Ju Lim, Dae Geun Kim, Wongi Min, Gon Sup Kim, Hu Jang Lee, Man Hee Rhee, Hyun Park, Sam Churl Kim, Hong Hee Chang, Suk Kim
Avian Pathology.2012; 41(4): 403. CrossRef
In Vitro Antibacterial Activity of Galls ofQuercus infectoriaOlivier against Oral Pathogens
Dayang Fredalina Basri, Liy Si Tan, Zaleha Shafiei, Noraziah Mohamad Zin
Evidence-Based Complementary and Alternative Medicine.2012; 2012: 1. CrossRef
Involvement of reactive oxygen species and glutathione in gallic acid-induced human umbilical vein endothelial cell death
WOO HYUN PARK, SUHN HEE KIM
Oncology Reports.2012; 28(2): 695. CrossRef
Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways
Ching-Lung Liao, Kuang-Chi Lai, An-Cheng Huang, Jai-Sing Yang, Jen-Jyh Lin, Shin-Hwar Wu, W. Gibson Wood, Jaung-Geng Lin, Jing-Gung Chung
Food and Chemical Toxicology.2012; 50(5): 1734. CrossRef
Gallic acid downregulates matrix metalloproteinase‐2 (MMP‐2) and MMP‐9 in human leukemia cells with expressed Bcr/Abl
Ying‐Jung Chen, Long‐Sen Chang
Molecular Nutrition & Food Research.2012; 56(9): 1398. CrossRef
New hybrid materials based on layered double hydroxides and antioxidant compounds. Preparation, characterization and release kinetic studies
Mihaela Silion, Doina Hritcu, Gabriela Lisa, Marcel Ionel Popa
Journal of Porous Materials.2012; 19(3): 267. CrossRef
The activity of ferulic and gallic acids in biofilm prevention and control of pathogenic bacteria
Anabela Borges, Maria J. Saavedra, Manuel Simões
Biofouling.2012; 28(7): 755. CrossRef
Biomimetic growth of gallic acid–ZnO hybrid assemblies and their applications
Nazmul H. Sarker, Stacey N. Barnaby, Karl R. Fath, Stephen H. Frayne, Nako Nakatsuka, Ipsita A. Banerjee
Journal of Nanoparticle Research.2012;[Epub] CrossRef
Inhibitory Effects of Chinese Medicinal Herbs on Plant-Pathogenic Bacteria and Identification of the Active Components from Gallnuts of Chinese Sumac
C. T. Feng, H. J. Su, C. T. Chen, W. C. Ho, Y. R. Tsou, L. L. Chern
Plant Disease.2012; 96(8): 1193. CrossRef
Effectiveness of egg yolk immunoglobulin (IgY) against periodontal disease-causing Fusobacterium nucleatum
F.X. Xu, Y.P. Xu, L.J. Jin, H. Liu, L.H. Wang, J.S. You, S.Y. Li, X.Y. Li
Journal of Applied Microbiology.2012; 113(4): 983. CrossRef
Enhancement of gallic acid-induced human pulmonary fibroblast cell death by N-acetyl cysteine and L-buthionine sulfoximine
Bo Ra You, Woo Hyun Park
Human & Experimental Toxicology.2011; 30(8): 992. CrossRef
The Effects of Mitogen-Activated Protein Kinase Inhibitors or Small Interfering RNAs on Gallic Acid-Induced HeLa Cell Death in Relation to Reactive Oxygen Species and Glutathione
Bo Ra You, Woo Hyun Park
Journal of Agricultural and Food Chemistry.2011; 59(2): 763. CrossRef
Surface modified dendrimers: Synthesis and characterization for cancer targeted drug delivery
Anupama Sharma, Surya Prakash Gautam, Arun Kumar Gupta
Bioorganic & Medicinal Chemistry.2011; 19(11): 3341. CrossRef
Identification and Quantification of Phenolic Compounds in Bambangan (Mangifera pajang Kort.) Peels and Their Free Radical Scavenging Activity
Fouad Abdulrahman Hassan, Amin Ismail, Azizah Abdulhamid, Azrina Azlan
Journal of Agricultural and Food Chemistry.2011; 59(17): 9102. CrossRef
Inhibition of Nitric Oxide Production by Ethyl Digallates Isolated from Galla Rhois in RAW 264.7 Macrophages
Pil-Hoon Park, Jin Hur, Dong-Sung Lee, Youn-Chul Kim, Gil-Saeng Jeong, Dong-Hwan Sohn
Biomolecules and Therapeutics.2011; 19(4): 419. CrossRef
Gallic acid-induced lung cancer cell death is accompanied by ROS increase and glutathione depletion
Bo Ra You, Sung Zoo Kim, Suhn Hee Kim, Woo Hyun Park
Molecular and Cellular Biochemistry.2011; 357(1-2): 295. CrossRef
Concentration of phenolic compounds in aqueous mate (Ilex paraguariensis A. St. Hil) extract through nanofiltration
Aureanna Nairne Negrão Murakami, Renata Dias de Mello Castanho Amboni, Elane Schwinden Prudêncio, Edna Regina Amante, Laura de Moraes Zanotta, Marcelo Maraschin, José Carlos Cunha Petrus, Reinaldo Francisco Teófilo
LWT - Food Science and Technology.2011; 44(10): 2211. CrossRef
Effect ofWeissella cibariaonFusobacterium nucleatum-induced Interleukin-6 and Interleukin-8 Production in KB Cells
Mi-Sun Kang, Hoi-Soon Lim, Seon-Mi Kim, Hyun-Chul Lee, Jong-Suk Oh
Journal of Bacteriology and Virology.2011; 41(1): 9. CrossRef
Gallic Acid Induces G2/M Phase Arrest of Breast Cancer Cell MCF-7 through Stabilization of p27Kip1 Attributed to Disruption of p27Kip1/Skp2 Complex
Jeng-Dong Hsu, Shao-Hsuan Kao, Ting-Tsz Ou, Yu-Jen Chen, Yi-Ju Li, Chau-Jong Wang
Journal of Agricultural and Food Chemistry.2011; 59(5): 1996. CrossRef
Gallic acid–induced human pulmonary fibroblast cell death is accompanied by increases in ROS level and GSH depletion
Bo Ra You, Woo Hyun Park
Drug and Chemical Toxicology.2011; 34(1): 38. CrossRef
Anticancer property of gallic acid in A549, a human lung adenocarcinoma cell line, and possible mechanisms
Dharmendra K. Maurya, Nivedita Nandakumar, Thomas Paul Asir Devasagayam
Journal of Clinical Biochemistry and Nutrition.2010; 48(1): 85. CrossRef
Cistaceae aqueous extracts containing ellagitannins show antioxidant and antimicrobial capacity, and cytotoxic activity against human cancer cells
Enrique Barrajón-Catalán, Salvador Fernández-Arroyo, Domingo Saura, Emilio Guillén, Alberto Fernández-Gutiérrez, Antonio Segura-Carretero, Vicente Micol
Food and Chemical Toxicology.2010; 48(8-9): 2273. CrossRef
Gallic acid inhibits the growth of HeLa cervical cancer cells via apoptosis and/or necrosis
Bo Ra You, Hwa Jin Moon, Yong Hwan Han, Woo Hyun Park
Food and Chemical Toxicology.2010; 48(5): 1334. CrossRef
Heme oxygenase-1 mediated protective effect of methyl gallate on cadmium-induced cytotoxicity in cultured mouse mesangial cells
Seok Ho Cha, Chang Kook Suh
Molecular & Cellular Toxicology.2010; 6(2): 127. CrossRef
Inhibitory Effect of Gallic Acid and Its Esters on 2,2′-Azobis(2-amidinopropane)hydrochloride (AAPH)-Induced Hemolysis and Depletion of Intracellular Glutathione in Erythrocytes
Valdecir F. Ximenes, Mariana G. Lopes, Maicon Segalla Petrônio, Luis Octavio Regasini, Dulce H. Siqueira Silva, Luiz M. da Fonseca
Journal of Agricultural and Food Chemistry.2010; 58(9): 5355. CrossRef
Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase
Bo Ra You, Woo Hyun Park
Toxicology in Vitro.2010; 24(5): 1356. CrossRef
Rhus chinensisandGalla Chinensis– folklore to modern evidence: review
Odilon Djakpo, Weirong Yao
Phytotherapy Research.2010; 24(12): 1739. CrossRef
Effects of methyl gallate and gallic acid on the production of inflammatory mediators interleukin-6 and interleukin-8 by oral epithelial cells stimulated with Fusobacterium nucleatum
Mi-Sun Kang, Hee-Sook Jang, Jong-Suk Oh, Kyu-Ho Yang, Nam-Ki Choi, Hoi-Soon Lim, Seon-Mi Kim
The Journal of Microbiology.2009; 47(6): 760. CrossRef
Gallic Acid, an Active Constituent of Grape Seed Extract, Exhibits Anti-proliferative, Pro-apoptotic and Anti-tumorigenic Effects Against Prostate Carcinoma Xenograft Growth in Nude Mice
Manjinder Kaur, Balaiya Velmurugan, Subapriya Rajamanickam, Rajesh Agarwal, Chapla Agarwal
Pharmaceutical Research.2009; 26(9): 2133. CrossRef
Comparative pharmacokinetic study of paeoniflorin after oral administration of pure paeoniflorin, extract of Cortex Moutan and Shuang-Dan prescription to rats
Hao Wu, Zhenyu Zhu, Guoqing Zhang, Liang Zhao, Hai Zhang, Dongliang Zhu, Yifeng Chai
Journal of Ethnopharmacology.2009; 125(3): 444. CrossRef

Research Support, Non-U.S. Gov't

Protective Effect of Polygoni Cuspidati Radix and Emodin on Vibrio vulnificus Cytotoxicity and Infection: Jong Ro Kim , Dool-Ri Oh , Mi Hye Cha , Byoung Sik Pyo , Joon Haeng Rhee , Hyon E. Choy , Won Keun Oh , Young Ran Kim; J. Microbiol. 2008;46(6):737-743. Published online December 24, 2008; DOI: https://doi.org/10.1007/s12275-008-0232-x

30 View
0 Download
36 Scopus

Abstract: Vibrio vulnificus, a good model organism of bacterial septicemia, causes fatal septicemia manifesting a fulminating course and a high mortality rate within days. In order to identify new natural substances preventing V. vulnificus infection, a plant library was screened for inhibiting cytotoxicity to host cells by using Trypan blue staining and LDH assay. We found that Polygoni Cuspidati Radix potently suppressed the acute death of HeLa and RAW264.7 cells in a dose dependent manner. Further studies revealed that Polygoni Cuspidati Radix inhibited V. vulnificus growth and survival in HI broth and seawater, respectively. We confirmed that Polygoni Cuspidati Radix contained high level of emodin by thin layer chromatography (TLC). Emodin showed direct antibacterial activity against V. vulnificus. In addition, emodin prevented the morphologic damages and acute death of HeLa cells caused from V. vulnificus. The safety of Polygoni Cuspidati Radix and emodin to host cells was confirmed by MTT assay. Polygoni Cuspidati Radix and emodin protected mice from V. vulnificus infection.

Journal Article

Synergistic Antibacterial Effect between Silybin and N,N’-Dicyclohexylcarbodiimide in Clinical Pseudomonas aeruginosa Isolates: Hyun Jun Jung , Dong Gun Lee; J. Microbiol. 2008;46(4):462-467. Published online August 31, 2008; DOI: https://doi.org/10.1007/s12275-008-0138-7

33 View
0 Download
21 Scopus

Abstract: Silybin is a composition of the silymarin group as a hepatoprotective agent, and it exhibits various biological activities, including an antibacterial activity. In this study, the effects of a combination of silybin with N,N′-dicyclohexylcarbodiimide (DCCD) against clinical isolates of Pseudomonas aeruginosa were investigated. In the results of susceptibility assay, silybin showed more potent antibacterial activity in methicilin-resistant Staphylococcus aureus (MRSA) than in P. aeruginosa, but DCCD significantly increased the antibacterial activity of silybin in P. aeruginosa. The antibacterial activity of silybin was affected by the strong action of multidrug-resistant pumps rather than by a permeable disruption of lipopolysaccharide and silybin showed a remarkable synergistic activity in combination with some antibiotic agents against drug-resistant bacteria. Therefore, silybin has a potential as a combination therapeutic agent for treatment of infectious diseases by multidrug-resistant bacteria.

First
Prev
Page of 2
Next
Last

Search